JPWO2024053578A5 - - Google Patents

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Publication number
JPWO2024053578A5
JPWO2024053578A5 JP2024545636A JP2024545636A JPWO2024053578A5 JP WO2024053578 A5 JPWO2024053578 A5 JP WO2024053578A5 JP 2024545636 A JP2024545636 A JP 2024545636A JP 2024545636 A JP2024545636 A JP 2024545636A JP WO2024053578 A5 JPWO2024053578 A5 JP WO2024053578A5
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JP
Japan
Prior art keywords
nucleic acid
nucleophile
protecting group
mass
deprotecting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024545636A
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English (en)
Japanese (ja)
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JPWO2024053578A1 (https=
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/JP2023/032085 external-priority patent/WO2024053578A1/ja
Publication of JPWO2024053578A1 publication Critical patent/JPWO2024053578A1/ja
Publication of JPWO2024053578A5 publication Critical patent/JPWO2024053578A5/ja
Pending legal-status Critical Current

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JP2024545636A 2022-09-07 2023-09-01 Pending JPWO2024053578A1 (https=)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2022142150 2022-09-07
PCT/JP2023/032085 WO2024053578A1 (ja) 2022-09-07 2023-09-01 核酸の製造方法、不純物の除去方法及び不純物が少ない核酸

Publications (2)

Publication Number Publication Date
JPWO2024053578A1 JPWO2024053578A1 (https=) 2024-03-14
JPWO2024053578A5 true JPWO2024053578A5 (https=) 2025-05-14

Family

ID=90191003

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024545636A Pending JPWO2024053578A1 (https=) 2022-09-07 2023-09-01

Country Status (5)

Country Link
US (1) US20250361540A1 (https=)
EP (1) EP4585604A4 (https=)
JP (1) JPWO2024053578A1 (https=)
CN (1) CN119855824A (https=)
WO (1) WO2024053578A1 (https=)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6036493A (ja) * 1983-08-08 1985-02-25 Nippon Zeon Co Ltd 保護された核酸関連物質の分離法
JPH07227284A (ja) 1994-02-15 1995-08-29 Takaaki Oishi 合成ｄｎａの処理方法
US6887990B1 (en) * 1999-02-05 2005-05-03 Amersham Biosciences Corp Method for deprotecting oligonucleotides
AU2003216830A1 (en) 2002-03-21 2003-10-08 Avecia Biotechnology Inc. Purification methods for oligonucleotides and their analogs
GB201115218D0 (en) 2011-09-02 2011-10-19 Glaxo Group Ltd Novel process
BR112018075667B1 (pt) 2016-06-14 2024-02-20 Biogen Ma, Inc Métodos para separar um oligonucleotídeo alvo de uma mistura contendo o oligonucleotídeo alvo e uma impureza relacionada com o produto
JP7720788B2 (ja) 2019-06-25 2025-08-08 アムジエン・インコーポレーテツド 炭水化物に連結されたオリゴヌクレオチドのための精製方法
JPWO2021045141A1 (https=) * 2019-09-04 2021-03-11

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