JPWO2024053578A1 - - Google Patents

Info

Publication number
JPWO2024053578A1
JPWO2024053578A1 JP2024545636A JP2024545636A JPWO2024053578A1 JP WO2024053578 A1 JPWO2024053578 A1 JP WO2024053578A1 JP 2024545636 A JP2024545636 A JP 2024545636A JP 2024545636 A JP2024545636 A JP 2024545636A JP WO2024053578 A1 JPWO2024053578 A1 JP WO2024053578A1
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024545636A
Other languages
Japanese (ja)
Other versions
JPWO2024053578A5 (https=
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of JPWO2024053578A1 publication Critical patent/JPWO2024053578A1/ja
Publication of JPWO2024053578A5 publication Critical patent/JPWO2024053578A5/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C07H1/06—Separation; Purification
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Saccharide Compounds (AREA)
JP2024545636A 2022-09-07 2023-09-01 Pending JPWO2024053578A1 (https=)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2022142150 2022-09-07
PCT/JP2023/032085 WO2024053578A1 (ja) 2022-09-07 2023-09-01 核酸の製造方法、不純物の除去方法及び不純物が少ない核酸

Publications (2)

Publication Number Publication Date
JPWO2024053578A1 true JPWO2024053578A1 (https=) 2024-03-14
JPWO2024053578A5 JPWO2024053578A5 (https=) 2025-05-14

Family

ID=90191003

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024545636A Pending JPWO2024053578A1 (https=) 2022-09-07 2023-09-01

Country Status (5)

Country Link
US (1) US20250361540A1 (https=)
EP (1) EP4585604A4 (https=)
JP (1) JPWO2024053578A1 (https=)
CN (1) CN119855824A (https=)
WO (1) WO2024053578A1 (https=)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6036493A (ja) * 1983-08-08 1985-02-25 Nippon Zeon Co Ltd 保護された核酸関連物質の分離法
JP2002536381A (ja) * 1999-02-05 2002-10-29 アマーシャム・ファルマシア・バイオテック・インコーポレーテッド オリゴヌクレオチドを脱保護するための方法
JP2014525254A (ja) * 2011-09-02 2014-09-29 グラクソ グループ リミテッド 混合物から目的のオリゴヌクレオチドを分離するためのプロセス
JP2019518759A (ja) * 2016-06-14 2019-07-04 バイオジェン・エムエイ・インコーポレイテッドＢｉｏｇｅｎ ＭＡ Ｉｎｃ． オリゴヌクレオチドの精製のための疎水性相互作用クロマトグラフィー
WO2021045141A1 (ja) * 2019-09-04 2021-03-11 神戸天然物化学株式会社 オリゴヌクレオチドの脱保護方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07227284A (ja) 1994-02-15 1995-08-29 Takaaki Oishi 合成ｄｎａの処理方法
CN1643145A (zh) 2002-03-21 2005-07-20 艾夫西亚生物科技公司 寡核苷酸及其类似物的纯化方法
AU2020301419B2 (en) 2019-06-25 2026-03-19 Amgen Inc. Purification methods for carbohydrate-linked oligonucleotides

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6036493A (ja) * 1983-08-08 1985-02-25 Nippon Zeon Co Ltd 保護された核酸関連物質の分離法
JP2002536381A (ja) * 1999-02-05 2002-10-29 アマーシャム・ファルマシア・バイオテック・インコーポレーテッド オリゴヌクレオチドを脱保護するための方法
JP2014525254A (ja) * 2011-09-02 2014-09-29 グラクソ グループ リミテッド 混合物から目的のオリゴヌクレオチドを分離するためのプロセス
JP2019518759A (ja) * 2016-06-14 2019-07-04 バイオジェン・エムエイ・インコーポレイテッドＢｉｏｇｅｎ ＭＡ Ｉｎｃ． オリゴヌクレオチドの精製のための疎水性相互作用クロマトグラフィー
WO2021045141A1 (ja) * 2019-09-04 2021-03-11 神戸天然物化学株式会社 オリゴヌクレオチドの脱保護方法

Also Published As

Publication number Publication date
CN119855824A (zh) 2025-04-18
EP4585604A1 (en) 2025-07-16
US20250361540A1 (en) 2025-11-27
WO2024053578A1 (ja) 2024-03-14
EP4585604A4 (en) 2026-04-08

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