JPWO2023049933A5 - - Google Patents
Info
- Publication number
- JPWO2023049933A5 JPWO2023049933A5 JP2024518776A JP2024518776A JPWO2023049933A5 JP WO2023049933 A5 JPWO2023049933 A5 JP WO2023049933A5 JP 2024518776 A JP2024518776 A JP 2024518776A JP 2024518776 A JP2024518776 A JP 2024518776A JP WO2023049933 A5 JPWO2023049933 A5 JP WO2023049933A5
- Authority
- JP
- Japan
- Prior art keywords
- cell
- immune cell
- chimeric receptor
- cancer
- genetically engineered
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163248629P | 2021-09-27 | 2021-09-27 | |
| US63/248,629 | 2021-09-27 | ||
| US202263399324P | 2022-08-19 | 2022-08-19 | |
| US63/399,324 | 2022-08-19 | ||
| PCT/US2022/077103 WO2023049933A1 (en) | 2021-09-27 | 2022-09-27 | Chimeric receptor polypeptides in combination with trans metabolism molecules that re-direct glucose metabolites out of the glycolysis pathway and therapeutic uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2024536859A JP2024536859A (ja) | 2024-10-08 |
| JPWO2023049933A5 true JPWO2023049933A5 (https=) | 2025-10-06 |
| JP2024536859A5 JP2024536859A5 (https=) | 2025-10-06 |
Family
ID=83996759
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024518776A Pending JP2024536859A (ja) | 2021-09-27 | 2022-09-27 | 解糖経路からグルコース代謝産物を再誘導するトランス代謝分子と組み合わせたキメラ受容体ポリペプチド及びその治療的使用 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20240390495A1 (https=) |
| EP (1) | EP4408982A1 (https=) |
| JP (1) | JP2024536859A (https=) |
| KR (1) | KR20240069799A (https=) |
| AU (1) | AU2022349103A1 (https=) |
| CA (1) | CA3232833A1 (https=) |
| IL (1) | IL311712A (https=) |
| MX (1) | MX2024004009A (https=) |
| WO (1) | WO2023049933A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20210045418A (ko) * | 2018-08-14 | 2021-04-26 | 소티오, 엘엘씨 | 크렙스 사이클을 조정하는 트랜스 대사 분자와 조합된 키메라 항원 수용체 폴리펩타이드 및 이의 치료적 용도 |
| WO2024040207A1 (en) | 2022-08-19 | 2024-02-22 | Sotio Biotech Inc. | Genetically engineered natural killer (nk) cells with chimeric receptor polypeptides in combination with trans metabolism molecules and therapeutic uses thereof |
| US20260053924A1 (en) | 2022-08-19 | 2026-02-26 | Sotio Biotech Inc. | Genetically engineered immune cells with chimeric receptor polypeptides in combination with multiple trans metabolism molecules and therapeutic uses thereof |
| EP4694916A1 (en) | 2023-04-14 | 2026-02-18 | SOTIO Biotech Inc. | Engineered immune cells for treating cancer in combination with il-2/il-15 receptor ?? agonists |
| WO2024215987A1 (en) | 2023-04-14 | 2024-10-17 | Sotio Biotech Inc. | IMMUNE CELLS FOR TREATING CANCER IN COMBINATION WITH IL-15/IL-15Rα CONJUGATES |
| TW202521564A (zh) * | 2023-08-14 | 2025-06-01 | 美商英特利亞醫療公司 | 用於基於細胞之療法的ｃｄ７０ ｃａｒ－ｔ組合物及方法 |
Family Cites Families (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4650764A (en) | 1983-04-12 | 1987-03-17 | Wisconsin Alumni Research Foundation | Helper cell |
| US4777127A (en) | 1985-09-30 | 1988-10-11 | Labsystems Oy | Human retrovirus-related products and methods of diagnosing and treating conditions associated with said retrovirus |
| GB8702816D0 (en) | 1987-02-07 | 1987-03-11 | Al Sumidaie A M K | Obtaining retrovirus-containing fraction |
| US5219740A (en) | 1987-02-13 | 1993-06-15 | Fred Hutchinson Cancer Research Center | Retroviral gene transfer into diploid fibroblasts for gene therapy |
| US4980289A (en) | 1987-04-27 | 1990-12-25 | Wisconsin Alumni Research Foundation | Promoter deficient retroviral vector |
| AP129A (en) | 1988-06-03 | 1991-04-17 | Smithkline Biologicals S A | Expression of retrovirus gag protein eukaryotic cells |
| US5124263A (en) | 1989-01-12 | 1992-06-23 | Wisconsin Alumni Research Foundation | Recombination resistant retroviral helper cell and products produced thereby |
| JP2752788B2 (ja) | 1989-01-23 | 1998-05-18 | カイロン コーポレイション | 感染および過剰増殖障害の為の組換え療法 |
| US5399346A (en) | 1989-06-14 | 1995-03-21 | The United States Of America As Represented By The Department Of Health And Human Services | Gene therapy |
| JP4041535B2 (ja) | 1989-08-18 | 2008-01-30 | オックスフォード バイオメディカ（ユーケー）リミテッド | 標的細胞にベクター構造体を運搬する組換レトロウィルス |
| US5585362A (en) | 1989-08-22 | 1996-12-17 | The Regents Of The University Of Michigan | Adenovirus vectors for gene therapy |
| JP3534749B2 (ja) | 1991-08-20 | 2004-06-07 | アメリカ合衆国 | アデノウイルスが介在する胃腸管への遺伝子の輸送 |
| WO1993010218A1 (en) | 1991-11-14 | 1993-05-27 | The United States Government As Represented By The Secretary Of The Department Of Health And Human Services | Vectors including foreign genes and negative selective markers |
| GB9125623D0 (en) | 1991-12-02 | 1992-01-29 | Dynal As | Cell modification |
| FR2688514A1 (fr) | 1992-03-16 | 1993-09-17 | Centre Nat Rech Scient | Adenovirus recombinants defectifs exprimant des cytokines et medicaments antitumoraux les contenant. |
| EP0650370A4 (en) | 1992-06-08 | 1995-11-22 | Univ California | METHODS AND COMPOSITIONS TARGETED ON SPECIFIC TISSUES. |
| CA2137361A1 (en) | 1992-06-10 | 1993-12-23 | W. French Anderson | Vector particles resistant to inactivation by human serum |
| GB2269175A (en) | 1992-07-31 | 1994-02-02 | Imperial College | Retroviral vectors |
| AU680459B2 (en) | 1992-12-03 | 1997-07-31 | Genzyme Corporation | Gene therapy for cystic fibrosis |
| ES2249761T3 (es) | 1993-06-24 | 2006-04-01 | Advec Inc. | Vectores de adenovirus para terapia genica. |
| CA2168202A1 (en) | 1993-07-30 | 1995-03-16 | Joseph Dougherty | Efficient gene transfer into primary lymphocytes |
| EP1637608B1 (en) | 1993-10-25 | 2009-07-22 | CANJI, Inc. | Recombinant adenoviral vector and methods of use |
| US5756910A (en) | 1996-08-28 | 1998-05-26 | Burgett, Inc. | Method and apparatus for actuating solenoids in a player piano |
| ES2278399T3 (es) | 1996-11-20 | 2007-08-01 | Introgen Therapeutics, Inc. | Metodo mejorado para la produccion y purificacion de vectores adenovirales. |
| GB9809951D0 (en) | 1998-05-08 | 1998-07-08 | Univ Cambridge Tech | Binding molecules |
| EP1135495A2 (en) | 1998-12-01 | 2001-09-26 | Genentech, Inc. | Secreted amd transmembrane polypeptides and nucleic acids encoding the same |
| US7052906B1 (en) | 1999-04-16 | 2006-05-30 | Celltech R & D Limited | Synthetic transmembrane components |
| US7435596B2 (en) | 2004-11-04 | 2008-10-14 | St. Jude Children's Research Hospital, Inc. | Modified cell line and method for expansion of NK cell |
| CA2748314C (en) | 2009-02-03 | 2018-10-02 | Amunix Operating Inc. | Extended recombinant polypeptides and compositions comprising same |
| PH12013501201A1 (en) | 2010-12-09 | 2013-07-29 | Univ Pennsylvania | Use of chimeric antigen receptor-modified t cells to treat cancer |
| WO2013040557A2 (en) | 2011-09-16 | 2013-03-21 | The Trustees Of The University Of Pennsylvania | Rna engineered t cells for the treatment of cancer |
| EP3057986B1 (en) | 2013-10-17 | 2017-12-27 | National University of Singapore | Chimeric receptor that triggers antibody-dependent cell cytotoxicity against multiple tumors |
| US20180133252A9 (en) | 2014-09-09 | 2018-05-17 | Unum Therapeutics Inc. | Chimeric receptors and uses thereof in immune therapy |
| EP3430036A4 (en) | 2016-03-18 | 2019-08-14 | Unum Therapeutics | MODIFIED CHIMERIC RECEPTORS AND USES IN IMMUNOTHERAPY |
| EP3573660A4 (en) | 2017-01-30 | 2021-01-06 | Unum Therapeutics Inc. | IMPROVED ANTIBODY T-LYMPHOCYTE RECEPTOR CONSTRUCTIONS AND THEIR THERAPEUTIC USES |
| CA3104862A1 (en) | 2018-07-03 | 2020-01-09 | Sotio, LLC | Chimeric receptors in combination with trans metabolism molecules enhancing glucose import and therapeutic uses thereof |
| KR20210045418A (ko) | 2018-08-14 | 2021-04-26 | 소티오, 엘엘씨 | 크렙스 사이클을 조정하는 트랜스 대사 분자와 조합된 키메라 항원 수용체 폴리펩타이드 및 이의 치료적 용도 |
-
2022
- 2022-09-27 WO PCT/US2022/077103 patent/WO2023049933A1/en not_active Ceased
- 2022-09-27 CA CA3232833A patent/CA3232833A1/en active Pending
- 2022-09-27 MX MX2024004009A patent/MX2024004009A/es unknown
- 2022-09-27 US US18/695,383 patent/US20240390495A1/en active Pending
- 2022-09-27 JP JP2024518776A patent/JP2024536859A/ja active Pending
- 2022-09-27 AU AU2022349103A patent/AU2022349103A1/en active Pending
- 2022-09-27 IL IL311712A patent/IL311712A/en unknown
- 2022-09-27 EP EP22797213.0A patent/EP4408982A1/en active Pending
- 2022-09-27 KR KR1020247013967A patent/KR20240069799A/ko active Pending
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