JP2024536859A - 解糖経路からグルコース代謝産物を再誘導するトランス代謝分子と組み合わせたキメラ受容体ポリペプチド及びその治療的使用 - Google Patents

解糖経路からグルコース代謝産物を再誘導するトランス代謝分子と組み合わせたキメラ受容体ポリペプチド及びその治療的使用 Download PDF

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JP2024536859A
JP2024536859A JP2024518776A JP2024518776A JP2024536859A JP 2024536859 A JP2024536859 A JP 2024536859A JP 2024518776 A JP2024518776 A JP 2024518776A JP 2024518776 A JP2024518776 A JP 2024518776A JP 2024536859 A JP2024536859 A JP 2024536859A
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chimeric receptor
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マクギネス キャスリーン
エッテンバーグ セス
バロン ルーク
フレイ マイケル
ウィルソン チャールズ
モーツ グレゴリー
バドゥリ サムヤブラタ
ジェンセン エイミー
カイパー エミリー
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ソティオ バイオテック インコーポレイティド
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JP2024518776A 2021-09-27 2022-09-27 解糖経路からグルコース代謝産物を再誘導するトランス代謝分子と組み合わせたキメラ受容体ポリペプチド及びその治療的使用 Pending JP2024536859A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163248629P 2021-09-27 2021-09-27
US63/248,629 2021-09-27
US202263399324P 2022-08-19 2022-08-19
US63/399,324 2022-08-19
PCT/US2022/077103 WO2023049933A1 (en) 2021-09-27 2022-09-27 Chimeric receptor polypeptides in combination with trans metabolism molecules that re-direct glucose metabolites out of the glycolysis pathway and therapeutic uses thereof

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JP2024536859A true JP2024536859A (ja) 2024-10-08
JPWO2023049933A5 JPWO2023049933A5 (https=) 2025-10-06
JP2024536859A5 JP2024536859A5 (https=) 2025-10-06

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US (1) US20240390495A1 (https=)
EP (1) EP4408982A1 (https=)
JP (1) JP2024536859A (https=)
KR (1) KR20240069799A (https=)
AU (1) AU2022349103A1 (https=)
CA (1) CA3232833A1 (https=)
IL (1) IL311712A (https=)
MX (1) MX2024004009A (https=)
WO (1) WO2023049933A1 (https=)

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KR20210045418A (ko) * 2018-08-14 2021-04-26 소티오, 엘엘씨 크렙스 사이클을 조정하는 트랜스 대사 분자와 조합된 키메라 항원 수용체 폴리펩타이드 및 이의 치료적 용도
WO2024040207A1 (en) 2022-08-19 2024-02-22 Sotio Biotech Inc. Genetically engineered natural killer (nk) cells with chimeric receptor polypeptides in combination with trans metabolism molecules and therapeutic uses thereof
US20260053924A1 (en) 2022-08-19 2026-02-26 Sotio Biotech Inc. Genetically engineered immune cells with chimeric receptor polypeptides in combination with multiple trans metabolism molecules and therapeutic uses thereof
EP4694916A1 (en) 2023-04-14 2026-02-18 SOTIO Biotech Inc. Engineered immune cells for treating cancer in combination with il-2/il-15 receptor ?? agonists
WO2024215987A1 (en) 2023-04-14 2024-10-17 Sotio Biotech Inc. IMMUNE CELLS FOR TREATING CANCER IN COMBINATION WITH IL-15/IL-15Rα CONJUGATES
TW202521564A (zh) * 2023-08-14 2025-06-01 美商英特利亞醫療公司 用於基於細胞之療法的ｃｄ７０ ｃａｒ－ｔ組合物及方法

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