JP2021529559A5 - - Google Patents
Info
- Publication number
- JP2021529559A5 JP2021529559A5 JP2021522932A JP2021522932A JP2021529559A5 JP 2021529559 A5 JP2021529559 A5 JP 2021529559A5 JP 2021522932 A JP2021522932 A JP 2021522932A JP 2021522932 A JP2021522932 A JP 2021522932A JP 2021529559 A5 JP2021529559 A5 JP 2021529559A5
- Authority
- JP
- Japan
- Prior art keywords
- immune cell
- nucleotide sequence
- immune
- cancer
- polypeptide
- Prior art date
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024076738A JP2024102286A (ja) | 2018-07-03 | 2024-05-09 | グルコース輸入を向上させるトランス代謝分子と組み合わせたキメラ受容体及びその治療的使用 |
Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862693677P | 2018-07-03 | 2018-07-03 | |
| US201862693668P | 2018-07-03 | 2018-07-03 | |
| US62/693,677 | 2018-07-03 | ||
| US62/693,668 | 2018-07-03 | ||
| US201862713369P | 2018-08-01 | 2018-08-01 | |
| US62/713,369 | 2018-08-01 | ||
| US201862756698P | 2018-11-07 | 2018-11-07 | |
| US201862756664P | 2018-11-07 | 2018-11-07 | |
| US62/756,698 | 2018-11-07 | ||
| US62/756,664 | 2018-11-07 | ||
| PCT/US2019/040346 WO2020010110A1 (en) | 2018-07-03 | 2019-07-02 | Chimeric receptors in combination with trans metabolism molecules enhancing glucose import and therapeutic uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024076738A Division JP2024102286A (ja) | 2018-07-03 | 2024-05-09 | グルコース輸入を向上させるトランス代謝分子と組み合わせたキメラ受容体及びその治療的使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021529559A JP2021529559A (ja) | 2021-11-04 |
| JPWO2020010110A5 JPWO2020010110A5 (https=) | 2022-07-12 |
| JP2021529559A5 true JP2021529559A5 (https=) | 2022-07-12 |
Family
ID=69060204
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021522932A Pending JP2021529559A (ja) | 2018-07-03 | 2019-07-02 | グルコース輸入を向上させるトランス代謝分子と組み合わせたキメラ受容体及びその治療的使用 |
| JP2024076738A Pending JP2024102286A (ja) | 2018-07-03 | 2024-05-09 | グルコース輸入を向上させるトランス代謝分子と組み合わせたキメラ受容体及びその治療的使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024076738A Pending JP2024102286A (ja) | 2018-07-03 | 2024-05-09 | グルコース輸入を向上させるトランス代謝分子と組み合わせたキメラ受容体及びその治療的使用 |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP3817763B1 (https=) |
| JP (2) | JP2021529559A (https=) |
| KR (1) | KR20210030950A (https=) |
| CN (1) | CN112638402A (https=) |
| AU (1) | AU2019299439C1 (https=) |
| CA (1) | CA3104862A1 (https=) |
| IL (1) | IL279629A (https=) |
| WO (1) | WO2020010110A1 (https=) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020028656A1 (en) | 2018-08-01 | 2020-02-06 | Nantkwest, Inc. | A quadricistronic system comprising a homing receptor or a cytokine, and chimeric antigen receptor for genetic modification of immunotherapies |
| KR20210045418A (ko) | 2018-08-14 | 2021-04-26 | 소티오, 엘엘씨 | 크렙스 사이클을 조정하는 트랜스 대사 분자와 조합된 키메라 항원 수용체 폴리펩타이드 및 이의 치료적 용도 |
| EP4097219A4 (en) * | 2020-01-28 | 2023-10-11 | ImmunityBio, Inc. | Chimeric antigen receptor-modified nk-92 cells targeting egfr super-family receptors |
| US11230699B2 (en) | 2020-01-28 | 2022-01-25 | Immunitybio, Inc. | Chimeric antigen receptor-modified NK-92 cells targeting EGFR super-family receptors |
| US20230248824A1 (en) * | 2020-07-09 | 2023-08-10 | The Board of Trutees of the Leland Stanford Junior University | Immune cells with increased glycolytic flux |
| WO2022140361A1 (en) * | 2020-12-22 | 2022-06-30 | Ludwig Institute For Cancer Research Ltd | Genetically engineered lymphocytes for adoptive cell therapy |
| US20240108652A1 (en) * | 2021-02-18 | 2024-04-04 | University Of Florida Research Foundation, Incorporated | Enhancing metabolic fitness of t cells to treat cancer |
| WO2022226364A2 (en) * | 2021-04-23 | 2022-10-27 | Sorrento Therapeutics, Inc. | Dimeric antigen receptors (dars) that bind gd2 |
| WO2023049933A1 (en) | 2021-09-27 | 2023-03-30 | Sotio Biotech Inc. | Chimeric receptor polypeptides in combination with trans metabolism molecules that re-direct glucose metabolites out of the glycolysis pathway and therapeutic uses thereof |
| WO2023081455A2 (en) * | 2021-11-08 | 2023-05-11 | Memorial Sloan-Kettering Cancer Center | Immune cells expressing glucose transporter 5 (gluts) and compositions and methods including the same |
| US20250000906A1 (en) | 2021-11-16 | 2025-01-02 | Sotio Biotech Inc. | Treatment of myxoid/round cell liposarcoma patients |
| GB202118201D0 (en) | 2021-12-15 | 2022-01-26 | King S College London | Engineered immune cell |
| WO2023172916A2 (en) * | 2022-03-08 | 2023-09-14 | Synthekine, Inc. | Orthogonal gpc3 chimeric antigen receptor t cells |
| CN115678856A (zh) * | 2022-06-09 | 2023-02-03 | 郑州大学第一附属医院 | 一种肿瘤杀伤细胞及其应用 |
| US20260053924A1 (en) | 2022-08-19 | 2026-02-26 | Sotio Biotech Inc. | Genetically engineered immune cells with chimeric receptor polypeptides in combination with multiple trans metabolism molecules and therapeutic uses thereof |
| WO2024040207A1 (en) | 2022-08-19 | 2024-02-22 | Sotio Biotech Inc. | Genetically engineered natural killer (nk) cells with chimeric receptor polypeptides in combination with trans metabolism molecules and therapeutic uses thereof |
| EP4694916A1 (en) | 2023-04-14 | 2026-02-18 | SOTIO Biotech Inc. | Engineered immune cells for treating cancer in combination with il-2/il-15 receptor ?? agonists |
| WO2024215987A1 (en) | 2023-04-14 | 2024-10-17 | Sotio Biotech Inc. | IMMUNE CELLS FOR TREATING CANCER IN COMBINATION WITH IL-15/IL-15Rα CONJUGATES |
| TW202540408A (zh) * | 2024-01-09 | 2025-10-16 | 國立研究開發法人國立癌症研究中心 | 需要時葡萄糖攝取能力經強化之t細胞、細胞集團及含有此之醫藥組成物 |
| WO2025150522A1 (ja) * | 2024-01-09 | 2025-07-17 | 国立研究開発法人国立がん研究センター | サバイバーt細胞、サバイバーt細胞集団および医薬組成物 |
| JP7685726B1 (ja) * | 2024-01-09 | 2025-05-30 | 国立研究開発法人国立がん研究センター | サバイバーt細胞、サバイバーt細胞集団および医薬組成物 |
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|---|---|---|---|---|
| US4650764A (en) | 1983-04-12 | 1987-03-17 | Wisconsin Alumni Research Foundation | Helper cell |
| US4777127A (en) | 1985-09-30 | 1988-10-11 | Labsystems Oy | Human retrovirus-related products and methods of diagnosing and treating conditions associated with said retrovirus |
| GB8702816D0 (en) | 1987-02-07 | 1987-03-11 | Al Sumidaie A M K | Obtaining retrovirus-containing fraction |
| US5219740A (en) | 1987-02-13 | 1993-06-15 | Fred Hutchinson Cancer Research Center | Retroviral gene transfer into diploid fibroblasts for gene therapy |
| US4980289A (en) | 1987-04-27 | 1990-12-25 | Wisconsin Alumni Research Foundation | Promoter deficient retroviral vector |
| AP129A (en) | 1988-06-03 | 1991-04-17 | Smithkline Biologicals S A | Expression of retrovirus gag protein eukaryotic cells |
| US5124263A (en) | 1989-01-12 | 1992-06-23 | Wisconsin Alumni Research Foundation | Recombination resistant retroviral helper cell and products produced thereby |
| JP2752788B2 (ja) | 1989-01-23 | 1998-05-18 | カイロン コーポレイション | 感染および過剰増殖障害の為の組換え療法 |
| US5399346A (en) | 1989-06-14 | 1995-03-21 | The United States Of America As Represented By The Department Of Health And Human Services | Gene therapy |
| JP4041535B2 (ja) | 1989-08-18 | 2008-01-30 | オックスフォード バイオメディカ(ユーケー)リミテッド | 標的細胞にベクター構造体を運搬する組換レトロウィルス |
| US5585362A (en) | 1989-08-22 | 1996-12-17 | The Regents Of The University Of Michigan | Adenovirus vectors for gene therapy |
| JP3534749B2 (ja) | 1991-08-20 | 2004-06-07 | アメリカ合衆国 | アデノウイルスが介在する胃腸管への遺伝子の輸送 |
| WO1993010218A1 (en) | 1991-11-14 | 1993-05-27 | The United States Government As Represented By The Secretary Of The Department Of Health And Human Services | Vectors including foreign genes and negative selective markers |
| GB9125623D0 (en) | 1991-12-02 | 1992-01-29 | Dynal As | Cell modification |
| FR2688514A1 (fr) | 1992-03-16 | 1993-09-17 | Centre Nat Rech Scient | Adenovirus recombinants defectifs exprimant des cytokines et medicaments antitumoraux les contenant. |
| EP0650370A4 (en) | 1992-06-08 | 1995-11-22 | Univ California | METHODS AND COMPOSITIONS TARGETED ON SPECIFIC TISSUES. |
| CA2137361A1 (en) | 1992-06-10 | 1993-12-23 | W. French Anderson | Vector particles resistant to inactivation by human serum |
| GB2269175A (en) | 1992-07-31 | 1994-02-02 | Imperial College | Retroviral vectors |
| AU680459B2 (en) | 1992-12-03 | 1997-07-31 | Genzyme Corporation | Gene therapy for cystic fibrosis |
| ES2249761T3 (es) | 1993-06-24 | 2006-04-01 | Advec Inc. | Vectores de adenovirus para terapia genica. |
| CA2168202A1 (en) | 1993-07-30 | 1995-03-16 | Joseph Dougherty | Efficient gene transfer into primary lymphocytes |
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| US5756910A (en) | 1996-08-28 | 1998-05-26 | Burgett, Inc. | Method and apparatus for actuating solenoids in a player piano |
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| US7052906B1 (en) | 1999-04-16 | 2006-05-30 | Celltech R & D Limited | Synthetic transmembrane components |
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| PH12013501201A1 (en) | 2010-12-09 | 2013-07-29 | Univ Pennsylvania | Use of chimeric antigen receptor-modified t cells to treat cancer |
| WO2013040557A2 (en) | 2011-09-16 | 2013-03-21 | The Trustees Of The University Of Pennsylvania | Rna engineered t cells for the treatment of cancer |
| EP3057986B1 (en) | 2013-10-17 | 2017-12-27 | National University of Singapore | Chimeric receptor that triggers antibody-dependent cell cytotoxicity against multiple tumors |
| US10246505B2 (en) * | 2013-11-25 | 2019-04-02 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Chimeric antigen receptors to control HIV infection |
| US20180133252A9 (en) | 2014-09-09 | 2018-05-17 | Unum Therapeutics Inc. | Chimeric receptors and uses thereof in immune therapy |
| US11020429B2 (en) * | 2015-11-05 | 2021-06-01 | Juno Therapeutics, Inc. | Vectors and genetically engineered immune cells expressing metabolic pathway modulators and uses in adoptive cell therapy |
| EP3430036A4 (en) | 2016-03-18 | 2019-08-14 | Unum Therapeutics | MODIFIED CHIMERIC RECEPTORS AND USES IN IMMUNOTHERAPY |
| US11377637B2 (en) * | 2016-04-15 | 2022-07-05 | Memorial Sloan Kettering Cancer Center | Transgenic T cell and chimeric antigen receptor T cell compositions and related methods |
| CN105949324B (zh) * | 2016-06-30 | 2019-08-27 | 上海恒润达生生物科技有限公司 | 靶向gpc3的嵌合抗原受体及其用途 |
| EP4342978A3 (en) * | 2016-09-01 | 2024-07-03 | Chimera Bioengineering Inc. | Gold optimized car t-cells |
| EP4282969A3 (en) * | 2016-09-02 | 2024-01-31 | Lentigen Technology, Inc. | Compositions and methods for treating cancer with duocars |
| EP3523331A1 (en) * | 2016-10-07 | 2019-08-14 | Novartis AG | Chimeric antigen receptors for the treatment of cancer |
| AU2019336229A1 (en) * | 2018-09-07 | 2021-03-18 | Sotio, LLC | Chimeric receptor polypeptides in combination with trans metabolism molecules modulating intracellular lactate concentrations and therapeutic uses thereof |
-
2019
- 2019-07-02 CA CA3104862A patent/CA3104862A1/en active Pending
- 2019-07-02 EP EP19831325.6A patent/EP3817763B1/en active Active
- 2019-07-02 CN CN201980056724.9A patent/CN112638402A/zh active Pending
- 2019-07-02 JP JP2021522932A patent/JP2021529559A/ja active Pending
- 2019-07-02 AU AU2019299439A patent/AU2019299439C1/en active Active
- 2019-07-02 KR KR1020217003418A patent/KR20210030950A/ko not_active Ceased
- 2019-07-02 WO PCT/US2019/040346 patent/WO2020010110A1/en not_active Ceased
-
2020
- 2020-12-21 IL IL279629A patent/IL279629A/en unknown
-
2024
- 2024-05-09 JP JP2024076738A patent/JP2024102286A/ja active Pending
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