JPWO2022230912A5 - - Google Patents
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- Publication number
- JPWO2022230912A5 JPWO2022230912A5 JP2023517579A JP2023517579A JPWO2022230912A5 JP WO2022230912 A5 JPWO2022230912 A5 JP WO2022230912A5 JP 2023517579 A JP2023517579 A JP 2023517579A JP 2023517579 A JP2023517579 A JP 2023517579A JP WO2022230912 A5 JPWO2022230912 A5 JP WO2022230912A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- alkylene
- different
- cycloalkyl
- optionally substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021075905 | 2021-04-28 | ||
| PCT/JP2022/018994 WO2022230912A1 (ja) | 2021-04-28 | 2022-04-27 | 置換トリアジン化合物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPWO2022230912A1 JPWO2022230912A1 (https=) | 2022-11-03 |
| JPWO2022230912A5 true JPWO2022230912A5 (https=) | 2025-05-07 |
Family
ID=83848494
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023517579A Pending JPWO2022230912A1 (https=) | 2021-04-28 | 2022-04-27 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20240239758A1 (https=) |
| EP (1) | EP4345097A4 (https=) |
| JP (1) | JPWO2022230912A1 (https=) |
| KR (1) | KR20240004371A (https=) |
| CN (1) | CN117222626A (https=) |
| AU (1) | AU2022267160A1 (https=) |
| BR (1) | BR112023022451A2 (https=) |
| CA (1) | CA3218212A1 (https=) |
| MX (1) | MX2023012795A (https=) |
| TW (1) | TW202309000A (https=) |
| WO (1) | WO2022230912A1 (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11618751B1 (en) | 2022-03-25 | 2023-04-04 | Ventus Therapeutics U.S., Inc. | Pyrido-[3,4-d]pyridazine amine derivatives useful as NLRP3 derivatives |
| US11319319B1 (en) | 2021-04-07 | 2022-05-03 | Ventus Therapeutics U.S., Inc. | Compounds for inhibiting NLRP3 and uses thereof |
| KR20240019083A (ko) | 2021-06-04 | 2024-02-14 | 에프. 호프만-라 로슈 아게 | 트리아진 유도체 및 암 치료에서 이의 용도 |
| HRP20251513T1 (hr) | 2021-07-02 | 2026-01-02 | Astrazeneca Ab | Inhibitori inflamasoma nlrp3 |
| CN116102535A (zh) * | 2021-10-22 | 2023-05-12 | 索智生物科技（浙江）有限公司 | 一种含氮化合物、其制备方法及应用 |
| IL314025A (en) * | 2022-01-07 | 2024-08-01 | Transthera Sciences Nanjing Inc | Nlrp3 inflammasome inhibitor and uses thereof |
| US12331048B2 (en) | 2022-10-31 | 2025-06-17 | Ventus Therapeutics U.S., Inc. | Pyrido-[3,4-d]pyridazine amine derivatives useful as NLRP3 inhibitors |
| WO2024094150A1 (en) * | 2022-11-04 | 2024-05-10 | Insilico Medicine Ip Limited | Nlrp3 inflammasome inhibitors and uses thereof |
| WO2024094185A1 (zh) * | 2022-11-04 | 2024-05-10 | 药捷安康(南京)科技股份有限公司 | Nlrp3炎症小体抑制剂及其应用 |
| WO2024157953A1 (ja) * | 2023-01-24 | 2024-08-02 | 第一三共株式会社 | 置換ベンゼン化合物 |
| CN120435466A (zh) * | 2023-02-17 | 2025-08-05 | 成都赜灵生物医药科技有限公司 | 六元氮杂环类化合物及其用途 |
| KR20250158072A (ko) * | 2023-03-20 | 2025-11-05 | 인실리코 메디신 아이피 리미티드 | Nlrp3 인플라마좀 억제제 및 이의 용도 |
| WO2024193699A1 (zh) * | 2023-03-23 | 2024-09-26 | 成都赜灵生物医药科技有限公司 | 三嗪类化合物及其用途 |
| AU2024280075A1 (en) | 2023-06-02 | 2025-12-11 | Merck Sharp & Dohme Llc | 5,6-Unsaturated Bicyclic Heterocycles Useful as Inhibitors of Nod-Like Receptor Protein 3 |
| WO2025059069A1 (en) * | 2023-09-12 | 2025-03-20 | Zomagen Biosciences Ltd | Nlrp3 modulators |
| WO2025153532A1 (en) | 2024-01-16 | 2025-07-24 | NodThera Limited | Nlrp3 inhibitors and glp-1 agonists combination therapies |
| CN118440041B (zh) * | 2024-07-02 | 2024-09-27 | 苏州凯瑞医药科技有限公司 | 一种手性4-氨基-3-羟基四氢吡喃的制备方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9133123B2 (en) | 2010-04-23 | 2015-09-15 | Cytokinetics, Inc. | Certain amino-pyridines and amino-triazines, compositions thereof, and methods for their use |
| US11447460B2 (en) | 2016-04-18 | 2022-09-20 | Novartis Ag | Compounds and compositions for treating conditions associated with NLRP activity |
| EP3272739A1 (en) | 2016-07-20 | 2018-01-24 | NodThera Limited | Sulfonyl urea derivatives and their use in the control of interleukin-1 activity |
| NZ760129A (en) | 2017-07-07 | 2025-12-19 | Inflazome Ltd | Novel sulfonamide carboxamide compounds |
| EA202092001A1 (ru) | 2018-03-27 | 2021-01-29 | ПиТиСи ТЕРАПЬЮТИКС, ИНК. | Соединения для лечения болезни гентингтона |
| KR102925387B1 (ko) | 2019-02-04 | 2026-02-10 | 스카이호크 테라퓨틱스, 인코포레이티드 | 스플라이싱을 조절하는 방법 및 조성물 |
| UY38687A (es) | 2019-05-17 | 2023-05-15 | Novartis Ag | Inhibidores del inflamasoma nlrp3, composiciones, combinaciones de los mismos y métodos para su uso |
| AR121669A1 (es) | 2020-03-27 | 2022-06-29 | Astellas Pharma Inc | Compuesto de piridazina sustituida |
| KR20240019083A (ko) * | 2021-06-04 | 2024-02-14 | 에프. 호프만-라 로슈 아게 | 트리아진 유도체 및 암 치료에서 이의 용도 |
| CN116102535A (zh) * | 2021-10-22 | 2023-05-12 | 索智生物科技（浙江）有限公司 | 一种含氮化合物、其制备方法及应用 |
-
2022
- 2022-04-27 US US18/288,588 patent/US20240239758A1/en active Pending
- 2022-04-27 BR BR112023022451A patent/BR112023022451A2/pt unknown
- 2022-04-27 CA CA3218212A patent/CA3218212A1/en active Pending
- 2022-04-27 KR KR1020237036874A patent/KR20240004371A/ko active Pending
- 2022-04-27 EP EP22795825.3A patent/EP4345097A4/en active Pending
- 2022-04-27 WO PCT/JP2022/018994 patent/WO2022230912A1/ja not_active Ceased
- 2022-04-27 CN CN202280031504.2A patent/CN117222626A/zh active Pending
- 2022-04-27 TW TW111116038A patent/TW202309000A/zh unknown
- 2022-04-27 AU AU2022267160A patent/AU2022267160A1/en active Pending
- 2022-04-27 MX MX2023012795A patent/MX2023012795A/es unknown
- 2022-04-27 JP JP2023517579A patent/JPWO2022230912A1/ja active Pending
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