JPWO2023003002A5 - - Google Patents
Info
- Publication number
- JPWO2023003002A5 JPWO2023003002A5 JP2023536766A JP2023536766A JPWO2023003002A5 JP WO2023003002 A5 JPWO2023003002 A5 JP WO2023003002A5 JP 2023536766 A JP2023536766 A JP 2023536766A JP 2023536766 A JP2023536766 A JP 2023536766A JP WO2023003002 A5 JPWO2023003002 A5 JP WO2023003002A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- different
- phenol
- amino
- pyridazin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021120560 | 2021-07-21 | ||
| PCT/JP2022/028138 WO2023003002A1 (ja) | 2021-07-21 | 2022-07-20 | 縮環ピリダジン化合物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPWO2023003002A1 JPWO2023003002A1 (https=) | 2023-01-26 |
| JPWO2023003002A5 true JPWO2023003002A5 (https=) | 2025-07-22 |
Family
ID=84980224
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023536766A Pending JPWO2023003002A1 (https=) | 2021-07-21 | 2022-07-20 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20250084092A1 (https=) |
| EP (1) | EP4375274A4 (https=) |
| JP (1) | JPWO2023003002A1 (https=) |
| KR (1) | KR20240059614A (https=) |
| CN (1) | CN118234711A (https=) |
| AU (1) | AU2022312986A1 (https=) |
| CA (1) | CA3226995A1 (https=) |
| IL (1) | IL310264A (https=) |
| MX (1) | MX2024000984A (https=) |
| TW (1) | TW202319055A (https=) |
| WO (1) | WO2023003002A1 (https=) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11618751B1 (en) | 2022-03-25 | 2023-04-04 | Ventus Therapeutics U.S., Inc. | Pyrido-[3,4-d]pyridazine amine derivatives useful as NLRP3 derivatives |
| US11319319B1 (en) | 2021-04-07 | 2022-05-03 | Ventus Therapeutics U.S., Inc. | Compounds for inhibiting NLRP3 and uses thereof |
| CR20240093A (es) | 2021-08-25 | 2024-05-23 | Ptc Therapeutics Inc | Inhibidores de NLRP3 |
| WO2023051761A1 (zh) * | 2021-09-30 | 2023-04-06 | 成都奥睿药业有限公司 | 一类取代杂芳酞嗪衍生物的药学用途及其制备方法 |
| WO2023066377A1 (zh) | 2021-10-22 | 2023-04-27 | 索智生物科技（浙江）有限公司 | 一种含氮化合物、其制备方法及应用 |
| WO2023088856A1 (en) | 2021-11-17 | 2023-05-25 | F. Hoffmann-La Roche Ag | Heterocyclic nlrp3 inhibitors |
| JP2025511199A (ja) * | 2022-03-31 | 2025-04-15 | ハンチョウ ハイライトゥル ファーマシューティカル カンパニー リミテッド | Ｎｌｒｐ３インフラマソーム阻害剤 |
| AR129012A1 (es) * | 2022-04-07 | 2024-07-03 | Takeda Pharmaceuticals Co | Derivados de piridazina fusionados |
| US20260015357A1 (en) * | 2022-07-01 | 2026-01-15 | Neumora Therapeutics, Inc. | Modulators of nlrp3 inflammasome and related products and methods |
| US12331048B2 (en) | 2022-10-31 | 2025-06-17 | Ventus Therapeutics U.S., Inc. | Pyrido-[3,4-d]pyridazine amine derivatives useful as NLRP3 inhibitors |
| WO2024109922A1 (zh) * | 2022-11-25 | 2024-05-30 | 成都赜灵生物医药科技有限公司 | 桥环并哒嗪类化合物及其用途 |
| KR20250135317A (ko) * | 2023-01-26 | 2025-09-12 | 다케다 야쿠힌 고교 가부시키가이샤 | 신경퇴행성 질환의 치료에 유용한 1-아미노-4-페닐프탈라진 유도체 |
| JP2026504419A (ja) | 2023-01-31 | 2026-02-05 | ヤンセン ファーマシューティカ エヌ．ベー． | Ｎｌｒｐ３阻害剤としての２－（ピリダジン－３－イル）－５－（トリフルオロメチル）フェノール |
| TW202448892A (zh) * | 2023-04-17 | 2024-12-16 | 大陸商上海拓界生物醫藥科技有限公司 | 稠合噠嗪類衍生物及其用途 |
| WO2025153532A1 (en) | 2024-01-16 | 2025-07-24 | NodThera Limited | Nlrp3 inhibitors and glp-1 agonists combination therapies |
| WO2026082103A1 (zh) * | 2024-10-16 | 2026-04-23 | 青岛博森泰科技有限公司 | 一种nlrp3抑制剂用于预防和/或治疗与体重增加相关的疾病或病症的用途 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006004589A2 (en) | 2004-05-08 | 2006-01-12 | Neurogen Corporation | 3-aryl-5,6-disubstituted pyridazines |
| WO2007130383A2 (en) * | 2006-04-28 | 2007-11-15 | Northwestern University | Compositions and treatments using pyridazine compounds and secretases |
| GB201309508D0 (en) | 2013-05-28 | 2013-07-10 | Redx Pharma Ltd | Compounds |
| GB201311953D0 (en) | 2013-07-03 | 2013-08-14 | Redx Pharma Ltd | Compounds |
| ES2940611T3 (es) | 2016-04-18 | 2023-05-09 | Novartis Ag | Compuestos y composiciones para el tratamiento de afecciones asociadas a la actividad de NLRP |
| EP3272739A1 (en) | 2016-07-20 | 2018-01-24 | NodThera Limited | Sulfonyl urea derivatives and their use in the control of interleukin-1 activity |
| US11465992B2 (en) | 2017-07-07 | 2022-10-11 | Inflazome Limited | Sulfonamide carboxamide compounds |
| AR119731A1 (es) | 2019-05-17 | 2022-01-05 | Novartis Ag | Inhibidores del inflamasoma nlrp3 |
| CA3155864A1 (en) | 2019-10-04 | 2021-04-08 | Vanderbilt University | Antagonists of the muscarinic acetylcholine receptor m4 |
| JP7356683B2 (ja) | 2020-01-31 | 2023-10-05 | 東京パワーテクノロジー株式会社 | ガスタービンの分解方法、組立方法、及び、治具 |
| CN115279739B (zh) | 2020-03-27 | 2025-07-22 | 尼科治疗有限公司 | 取代哒嗪化合物 |
| WO2022135567A1 (zh) * | 2020-12-25 | 2022-06-30 | 上海拓界生物医药科技有限公司 | 一类含哒嗪的化合物及其医药用途 |
| US11319319B1 (en) | 2021-04-07 | 2022-05-03 | Ventus Therapeutics U.S., Inc. | Compounds for inhibiting NLRP3 and uses thereof |
| CN115433163A (zh) * | 2021-06-05 | 2022-12-06 | 药捷安康(南京)科技股份有限公司 | Nlrp3炎症小体抑制剂及其应用 |
| EP4362946A4 (en) * | 2021-06-29 | 2025-05-21 | Zomagen Biosciences Ltd | Nlrp3 modulators |
| LT4363406T (lt) * | 2021-07-02 | 2025-12-29 | Astrazeneca Ab | Nlrp3 inflamasomų inhibitoriai |
| CR20240093A (es) * | 2021-08-25 | 2024-05-23 | Ptc Therapeutics Inc | Inhibidores de NLRP3 |
| WO2023051761A1 (zh) * | 2021-09-30 | 2023-04-06 | 成都奥睿药业有限公司 | 一类取代杂芳酞嗪衍生物的药学用途及其制备方法 |
| WO2023066377A1 (zh) * | 2021-10-22 | 2023-04-27 | 索智生物科技（浙江）有限公司 | 一种含氮化合物、其制备方法及应用 |
| AR129012A1 (es) * | 2022-04-07 | 2024-07-03 | Takeda Pharmaceuticals Co | Derivados de piridazina fusionados |
-
2022
- 2022-07-20 TW TW111127188A patent/TW202319055A/zh unknown
- 2022-07-20 US US18/580,746 patent/US20250084092A1/en active Pending
- 2022-07-20 MX MX2024000984A patent/MX2024000984A/es unknown
- 2022-07-20 IL IL310264A patent/IL310264A/en unknown
- 2022-07-20 CN CN202280061594.XA patent/CN118234711A/zh active Pending
- 2022-07-20 CA CA3226995A patent/CA3226995A1/en active Pending
- 2022-07-20 JP JP2023536766A patent/JPWO2023003002A1/ja active Pending
- 2022-07-20 AU AU2022312986A patent/AU2022312986A1/en active Pending
- 2022-07-20 WO PCT/JP2022/028138 patent/WO2023003002A1/ja not_active Ceased
- 2022-07-20 EP EP22845935.0A patent/EP4375274A4/en active Pending
- 2022-07-20 KR KR1020247005916A patent/KR20240059614A/ko active Pending
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