JPWO2022226374A5 - - Google Patents
Info
- Publication number
- JPWO2022226374A5 JPWO2022226374A5 JP2023565273A JP2023565273A JPWO2022226374A5 JP WO2022226374 A5 JPWO2022226374 A5 JP WO2022226374A5 JP 2023565273 A JP2023565273 A JP 2023565273A JP 2023565273 A JP2023565273 A JP 2023565273A JP WO2022226374 A5 JPWO2022226374 A5 JP WO2022226374A5
- Authority
- JP
- Japan
- Prior art keywords
- aav
- acid sequence
- amino acid
- capsid
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163178965P | 2021-04-23 | 2021-04-23 | |
| US63/178,965 | 2021-04-23 | ||
| US202263299697P | 2022-01-14 | 2022-01-14 | |
| US63/299,697 | 2022-01-14 | ||
| PCT/US2022/026048 WO2022226374A1 (en) | 2021-04-23 | 2022-04-22 | Tissue-targeted modified aav capsids and methods of use thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2024514956A JP2024514956A (ja) | 2024-04-03 |
| JP2024514956A5 JP2024514956A5 (https=) | 2026-03-17 |
| JPWO2022226374A5 true JPWO2022226374A5 (https=) | 2026-03-17 |
Family
ID=81598018
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023565273A Pending JP2024514956A (ja) | 2021-04-23 | 2022-04-22 | 組織標的化された改変ａａｖカプシドおよびその使用方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20240197918A1 (https=) |
| EP (1) | EP4326868A1 (https=) |
| JP (1) | JP2024514956A (https=) |
| CA (1) | CA3216419A1 (https=) |
| WO (1) | WO2022226374A1 (https=) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20230159949A1 (en) * | 2020-07-22 | 2023-05-25 | The Broad Institute, Inc. | Engineered muscle targeting compositions |
| MX2024004217A (es) | 2021-10-08 | 2024-06-26 | Dyno Therapeutics Inc | Variantes de cápside y métodos de uso de estas. |
| EP4353737A1 (en) * | 2022-10-10 | 2024-04-17 | Universitätsklinikum Hamburg-Eppendorf | Fusion proteins comprising a cell surface marker specific vhh |
| TW202502803A (zh) | 2023-03-10 | 2025-01-16 | 美商戴諾治療公司 | 衣殼多肽及其使用方法 |
| CN118955652A (zh) * | 2023-05-15 | 2024-11-15 | 杭州新昶基因技术有限公司 | 腺相关病毒衣壳蛋白、包含其的腺相关病毒及应用 |
| WO2024238807A2 (en) * | 2023-05-16 | 2024-11-21 | Affinia Therapeutics Inc. | Recombinant aavs with improved tropism and specificity |
| TW202525832A (zh) | 2023-08-31 | 2025-07-01 | 美商戴諾治療公司 | 衣殼多肽及其使用方法(二) |
| WO2025137378A1 (en) * | 2023-12-20 | 2025-06-26 | Aavantibio, Inc. | Aav capsid engineering for cardiac and/or musculoskeletal gene therapy |
| WO2025133247A1 (en) * | 2023-12-21 | 2025-06-26 | Genethon | Methods for aav vector re-administration |
| TW202545971A (zh) | 2024-02-08 | 2025-12-01 | 美商戴諾治療公司 | 殼體多肽及其使用方法 |
| WO2025185625A1 (zh) * | 2024-03-04 | 2025-09-12 | 苏州新芽基因生物技术有限公司 | 特异性靶向人组织的多肽序列及其在构建递送载体中的应用 |
| WO2025230000A1 (ja) * | 2024-05-01 | 2025-11-06 | Ｊｃｒファーマ株式会社 | 修飾されたａａｖ粒子、その製造方法、関連する医薬及びその製造 |
| WO2026064444A1 (en) | 2024-09-18 | 2026-03-26 | Dyno Therapeutics, Inc. | Capsid polypeptides and methods of use thereof |
| WO2026064428A2 (en) | 2024-09-18 | 2026-03-26 | Dyno Therapeutics, Inc. | Capsid polypeptides and methods of use thereof |
| WO2026064442A2 (en) | 2024-09-18 | 2026-03-26 | Dyno Therapeutics, Inc. | Capsid polypeptides and methods of use thereof |
| WO2026069251A1 (en) * | 2024-09-30 | 2026-04-02 | Sarepta Therapeutics, Inc. | Adeno-associated virus capsid antibodies and fragments thereof |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2406743A1 (en) | 2000-04-28 | 2001-11-08 | The Trustees Of The University Of Pennsylvania | Recombinant aav vectors with aav5 capsids and aav5 vectors pseudotyped in heterologous capsids |
| CN101895633A (zh) | 2010-07-14 | 2010-11-24 | 中兴通讯股份有限公司 | 一种移动终端及其解锁方法 |
| WO2012068627A1 (en) | 2010-11-24 | 2012-05-31 | The University Of Western Australia | Peptides for the specific binding of rna targets |
| WO2012109570A1 (en) * | 2011-02-10 | 2012-08-16 | The University Of North Carolina At Chapel Hill | Viral vectors with modified transduction profiles and methods of making and using the same |
| WO2013058404A1 (ja) | 2011-10-21 | 2013-04-25 | 国立大学法人九州大学 | Pprモチーフを利用したrna結合性蛋白質の設計方法及びその利用 |
| US9434928B2 (en) | 2011-11-23 | 2016-09-06 | Nationwide Children's Hospital, Inc. | Recombinant adeno-associated virus delivery of alpha-sarcoglycan polynucleotides |
| US10330674B2 (en) | 2015-01-13 | 2019-06-25 | Massachusetts Institute Of Technology | Pumilio domain-based modular protein architecture for RNA binding |
| AU2020368539A1 (en) * | 2019-10-16 | 2022-04-28 | Massachusetts Institute Of Technology | Engineered muscle targeting compositions |
| AU2021264061A1 (en) * | 2020-05-01 | 2022-12-01 | Massachusetts Institute Of Technology | Engineered central nervous system compositions |
| TW202217003A (zh) * | 2020-07-22 | 2022-05-01 | 美商博得學院股份有限公司 | 經改造之肌肉靶向組合物 |
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2022
- 2022-04-22 CA CA3216419A patent/CA3216419A1/en active Pending
- 2022-04-22 EP EP22722646.1A patent/EP4326868A1/en active Pending
- 2022-04-22 WO PCT/US2022/026048 patent/WO2022226374A1/en not_active Ceased
- 2022-04-22 JP JP2023565273A patent/JP2024514956A/ja active Pending
- 2022-04-22 US US18/287,963 patent/US20240197918A1/en active Pending