JPWO2022020616A5 - - Google Patents
Download PDFInfo
- Publication number
- JPWO2022020616A5 JPWO2022020616A5 JP2023504171A JP2023504171A JPWO2022020616A5 JP WO2022020616 A5 JPWO2022020616 A5 JP WO2022020616A5 JP 2023504171 A JP2023504171 A JP 2023504171A JP 2023504171 A JP2023504171 A JP 2023504171A JP WO2022020616 A5 JPWO2022020616 A5 JP WO2022020616A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- mutation
- aav
- viral
- disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063055265P | 2020-07-22 | 2020-07-22 | |
| US63/055,265 | 2020-07-22 | ||
| US202063107394P | 2020-10-29 | 2020-10-29 | |
| US63/107,394 | 2020-10-29 | ||
| US202163183038P | 2021-05-02 | 2021-05-02 | |
| US63/183,038 | 2021-05-02 | ||
| PCT/US2021/042812 WO2022020616A1 (en) | 2020-07-22 | 2021-07-22 | Engineered muscle targeting compositions |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023534999A JP2023534999A (ja) | 2023-08-15 |
| JP2023534999A5 JP2023534999A5 (https=) | 2024-07-26 |
| JPWO2022020616A5 true JPWO2022020616A5 (https=) | 2024-07-26 |
Family
ID=79728337
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023504171A Pending JP2023534999A (ja) | 2020-07-22 | 2021-07-22 | 操作された筋肉標的化組成物 |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP4185702A4 (https=) |
| JP (1) | JP2023534999A (https=) |
| KR (1) | KR20230053591A (https=) |
| CN (1) | CN116194153A (https=) |
| AU (1) | AU2021314256A1 (https=) |
| BR (1) | BR112023000909A2 (https=) |
| CA (1) | CA3183530A1 (https=) |
| CL (2) | CL2023000204A1 (https=) |
| CO (1) | CO2023000866A2 (https=) |
| IL (1) | IL299431A (https=) |
| MX (1) | MX2023000998A (https=) |
| TW (1) | TW202217003A (https=) |
| WO (1) | WO2022020616A1 (https=) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL297391A (en) | 2020-04-20 | 2022-12-01 | Tenaya Therapeutics Inc | An adeno-associated virus with an engineered capsid |
| WO2022173847A2 (en) * | 2021-02-09 | 2022-08-18 | Affinia Therapeutics Inc. | Recombinant aavs with improved tropism and specificity |
| CA3216419A1 (en) * | 2021-04-23 | 2022-10-27 | Greg NACHTRAB | Tissue-targeted modified aav capsids and methods of use thereof |
| US20250090688A1 (en) * | 2021-08-05 | 2025-03-20 | The Broad Institute, Inc. | Engineered muscle targeting compositions |
| CN118202060A (zh) | 2021-10-05 | 2024-06-14 | 再生生物股份有限公司 | 用于重组aav生产的组合物和方法 |
| WO2023060113A1 (en) | 2021-10-05 | 2023-04-13 | Regenxbio Inc. | Compositions and methods for recombinant aav production |
| MX2024004217A (es) | 2021-10-08 | 2024-06-26 | Dyno Therapeutics Inc | Variantes de cápside y métodos de uso de estas. |
| US20250249052A1 (en) * | 2022-04-07 | 2025-08-07 | Kate Therapeutics, Inc. | Compositions and methods for muscle disorders |
| WO2023198828A1 (en) * | 2022-04-13 | 2023-10-19 | Universitat Autònoma De Barcelona | Treatment of neuromuscular diseases via gene therapy that expresses klotho protein |
| EP4707399A2 (en) * | 2022-06-10 | 2026-03-11 | Généthon | Peptide-modified aav capsid with enhanced muscle transduction efficiency |
| KR20250135916A (ko) * | 2022-12-17 | 2025-09-15 | 더 트러스티스 오브 더 유니버시티 오브 펜실베니아 | 심장 및 골격근 특이적 표적화 모티프를 갖는 재조합 aav 돌연변이체 벡터 및 이를 포함하는 조성물 |
| TW202502803A (zh) | 2023-03-10 | 2025-01-16 | 美商戴諾治療公司 | 衣殼多肽及其使用方法 |
| EP4680741A2 (en) | 2023-03-15 | 2026-01-21 | RegenxBio Inc. | Exon skipping gene therapy constructs, vectors and uses thereof |
| TW202525832A (zh) | 2023-08-31 | 2025-07-01 | 美商戴諾治療公司 | 衣殼多肽及其使用方法(二) |
| WO2025090858A1 (en) * | 2023-10-27 | 2025-05-01 | Biogen Ma Inc. | Methods for identifying aav capsid variants with desired characteristics |
| TW202545971A (zh) | 2024-02-08 | 2025-12-01 | 美商戴諾治療公司 | 殼體多肽及其使用方法 |
| US20250276095A1 (en) | 2024-03-04 | 2025-09-04 | Kate Therapeutics, Inc. | Adeno-associated virus compositions for the treatment of duchenne muscular dystrophy |
| CN118667855A (zh) * | 2024-05-31 | 2024-09-20 | 扬州大学 | 一种具有肌肉靶向性促进骨形成的噬菌体的构建方法及其应用 |
| WO2025250909A1 (en) | 2024-05-31 | 2025-12-04 | Sarepta Therapeutics, Inc. | Muscle-tropic recombinant aav |
| WO2026006341A1 (en) | 2024-06-24 | 2026-01-02 | Regenxbio Inc. | Microdystrophin gene therapy administration for treatment of dystrophinopathies |
| WO2026011009A1 (en) | 2024-07-02 | 2026-01-08 | Kate Therapeutics, Inc. | Compositions and methods for muscle disorders |
| WO2026030242A1 (en) | 2024-07-29 | 2026-02-05 | Kate Therapeutics, Inc. | Adeno-associated virus compositions for the treatment of facioscapulohumeral muscular dystrophy |
| WO2026030244A1 (en) | 2024-07-30 | 2026-02-05 | Kate Therapeutics, Inc. | Adeno-associated virus compositions for the treatment of limb girdle muscular dystrophy 2a |
| WO2026041758A1 (en) | 2024-08-22 | 2026-02-26 | Genethon | Modified aav capsid with enhanced transduction efficiency |
| WO2026050402A1 (en) | 2024-08-29 | 2026-03-05 | Kate Therapeutics, Inc. | Liver de-targeted muscle tropic capsids |
| WO2026064442A2 (en) | 2024-09-18 | 2026-03-26 | Dyno Therapeutics, Inc. | Capsid polypeptides and methods of use thereof |
| WO2026064739A1 (en) * | 2024-09-23 | 2026-03-26 | Carbon Biosciences, Inc. | Parvovirus compositions and related methods for gene therapy |
| WO2026069251A1 (en) * | 2024-09-30 | 2026-04-02 | Sarepta Therapeutics, Inc. | Adeno-associated virus capsid antibodies and fragments thereof |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2019258830B2 (en) * | 2018-04-27 | 2025-12-18 | Universität Heidelberg | Modified AAV capsid polypeptides for treatment of muscular diseases |
| US12397084B2 (en) * | 2018-07-23 | 2025-08-26 | Georgia Tech Research Corporation | Synthetic hydrogel carriers for muscle repair |
| WO2021050974A1 (en) * | 2019-09-12 | 2021-03-18 | The Broad Institute, Inc. | Engineered adeno-associated virus capsids |
-
2021
- 2021-07-22 TW TW110126971A patent/TW202217003A/zh unknown
- 2021-07-22 CN CN202180054063.3A patent/CN116194153A/zh active Pending
- 2021-07-22 AU AU2021314256A patent/AU2021314256A1/en active Pending
- 2021-07-22 CA CA3183530A patent/CA3183530A1/en active Pending
- 2021-07-22 IL IL299431A patent/IL299431A/en unknown
- 2021-07-22 BR BR112023000909A patent/BR112023000909A2/pt unknown
- 2021-07-22 KR KR1020237004484A patent/KR20230053591A/ko active Pending
- 2021-07-22 EP EP21846426.1A patent/EP4185702A4/en active Pending
- 2021-07-22 WO PCT/US2021/042812 patent/WO2022020616A1/en not_active Ceased
- 2021-07-22 JP JP2023504171A patent/JP2023534999A/ja active Pending
- 2021-07-22 MX MX2023000998A patent/MX2023000998A/es unknown
-
2023
- 2023-01-20 CL CL2023000204A patent/CL2023000204A1/es unknown
- 2023-01-26 CO CONC2023/0000866A patent/CO2023000866A2/es unknown
-
2024
- 2024-01-30 CL CL2024000275A patent/CL2024000275A1/es unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JPWO2022020616A5 (https=) | ||
| JPWO2021077000A5 (https=) | ||
| AU2026202070A1 (en) | Modified AAV capsid polypeptides for treatment of muscular diseases | |
| JP2024009857A5 (https=) | ||
| JP6174318B2 (ja) | アデノ随伴ウイルス構築物を含んでなるコンダクティング気道細胞を標的とするための組成物 | |
| JP2021106619A5 (https=) | ||
| JP2024095717A5 (https=) | ||
| JP2024099770A5 (https=) | ||
| JP2022500066A5 (https=) | ||
| JP2020528734A5 (https=) | ||
| JP2020522269A5 (https=) | ||
| JP2021512649A5 (https=) | ||
| JP2021534814A5 (https=) | ||
| JP2020519284A5 (https=) | ||
| JP2024041821A5 (https=) | ||
| JPWO2021222831A5 (https=) | ||
| JPWO2020214609A5 (https=) | ||
| JP2021534766A5 (https=) | ||
| JPWO2022226374A5 (https=) | ||
| JP2025516136A5 (https=) | ||
| JPWO2023060142A5 (https=) | ||
| JPWO2023015297A5 (https=) | ||
| JPWO2021163556A5 (https=) | ||
| JPWO2020069339A5 (https=) | ||
| JPWO2020028816A5 (https=) |