JPWO2022067233A5 - - Google Patents

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Publication number
JPWO2022067233A5
JPWO2022067233A5 JP2023519180A JP2023519180A JPWO2022067233A5 JP WO2022067233 A5 JPWO2022067233 A5 JP WO2022067233A5 JP 2023519180 A JP2023519180 A JP 2023519180A JP 2023519180 A JP2023519180 A JP 2023519180A JP WO2022067233 A5 JPWO2022067233 A5 JP WO2022067233A5
Authority
JP
Japan
Prior art keywords
polypeptide
igg
substitution
constant domain
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023519180A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023543262A5 (https=
JP2023543262A (ja
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/052338 external-priority patent/WO2022067233A2/en
Publication of JP2023543262A publication Critical patent/JP2023543262A/ja
Publication of JPWO2022067233A5 publication Critical patent/JPWO2022067233A5/ja
Publication of JP2023543262A5 publication Critical patent/JP2023543262A5/ja
Pending legal-status Critical Current

Links

JP2023519180A 2020-09-28 2021-09-28 イヌ科動物抗体バリアント Pending JP2023543262A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063084241P 2020-09-28 2020-09-28
US63/084,241 2020-09-28
PCT/US2021/052338 WO2022067233A2 (en) 2020-09-28 2021-09-28 Canine antibody variants

Publications (3)

Publication Number Publication Date
JP2023543262A JP2023543262A (ja) 2023-10-13
JPWO2022067233A5 true JPWO2022067233A5 (https=) 2024-09-27
JP2023543262A5 JP2023543262A5 (https=) 2024-09-27

Family

ID=78599123

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023519180A Pending JP2023543262A (ja) 2020-09-28 2021-09-28 イヌ科動物抗体バリアント

Country Status (16)

Country Link
EP (1) EP4217384A2 (https=)
JP (1) JP2023543262A (https=)
KR (1) KR20230079148A (https=)
CN (1) CN116438196A (https=)
AR (1) AR123636A1 (https=)
AU (1) AU2021349301A1 (https=)
BR (1) BR112023005393A2 (https=)
CA (1) CA3194936A1 (https=)
CL (2) CL2023000878A1 (https=)
CO (1) CO2023004102A2 (https=)
EC (1) ECSP23030271A (https=)
IL (1) IL301413A (https=)
MX (1) MX2023003624A (https=)
PE (1) PE20231374A1 (https=)
TW (1) TW202229337A (https=)
WO (1) WO2022067233A2 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115996949A (zh) * 2020-04-17 2023-04-21 硕腾服务有限责任公司 犬抗体变异体
KR20250026186A (ko) * 2022-06-21 2025-02-25 조에티스 서비시즈 엘엘씨 갯과 항체 돌연변이체
JP2026508096A (ja) 2023-01-20 2026-03-10 ゾエティス・サービシーズ・ユーケー・リミテッド 治療抗体

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8308235D0 (en) 1983-03-25 1983-05-05 Celltech Ltd Polypeptides
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US5807715A (en) 1984-08-27 1998-09-15 The Board Of Trustees Of The Leland Stanford Junior University Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin
GB8422238D0 (en) 1984-09-03 1984-10-10 Neuberger M S Chimeric proteins
US5225539A (en) 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
US6284471B1 (en) 1991-03-18 2001-09-04 New York University Medical Center Anti-TNFa antibodies and assays employing anti-TNFa antibodies
US5698762A (en) 1994-12-09 1997-12-16 Dauerman; Leonard Microwave-assisted pyrolysis of waste polyaromatic hydrocarbons
US20030031671A1 (en) 2001-08-01 2003-02-13 Sydney Welt Methods of treating colon cancer utilizing tumor-specific antibodies
KR20070057839A (ko) 2004-08-19 2007-06-07 제넨테크, 인크. 변경된 이펙터 기능을 갖는 폴리펩티드 변이체
DK1817340T3 (da) 2004-11-12 2012-08-13 Xencor Inc Fc-varianter med ændret binding til fcrn
US8367805B2 (en) 2004-11-12 2013-02-05 Xencor, Inc. Fc variants with altered binding to FcRn
US8546543B2 (en) 2004-11-12 2013-10-01 Xencor, Inc. Fc variants that extend antibody half-life
US9505829B2 (en) 2010-08-19 2016-11-29 Zoetis Belgium S.A. Anti-NGF antibodies and their use
US8790651B2 (en) 2011-07-21 2014-07-29 Zoetis Llc Interleukin-31 monoclonal antibody
EP2859018B1 (en) 2012-06-06 2021-09-22 Zoetis Services LLC Caninized anti-ngf antibodies and methods thereof
CN113194984A (zh) * 2018-10-18 2021-07-30 金德雷德生物科学股份有限公司 兽用的与新生儿Fc受体(FcRn)结合改变的Fc变体
EP3887397A1 (en) * 2018-11-28 2021-10-06 Bristol-Myers Squibb Company Antibodies comprising modified heavy constant regions
CN113227134A (zh) * 2018-12-05 2021-08-06 株式会社梅花治疗 抗体的Fc区变体
US11542333B2 (en) * 2019-01-03 2023-01-03 Invetx, Inc. Compositions for increasing half-life of a therapeutic agent in canines and methods of use
CN115996949A (zh) * 2020-04-17 2023-04-21 硕腾服务有限责任公司 犬抗体变异体

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