JPWO2020209318A5 - - Google Patents
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- JPWO2020209318A5 JPWO2020209318A5 JP2021513692A JP2021513692A JPWO2020209318A5 JP WO2020209318 A5 JPWO2020209318 A5 JP WO2020209318A5 JP 2021513692 A JP2021513692 A JP 2021513692A JP 2021513692 A JP2021513692 A JP 2021513692A JP WO2020209318 A5 JPWO2020209318 A5 JP WO2020209318A5
- Authority
- JP
- Japan
- Prior art keywords
- domain
- amino acid
- residue
- igg antibody
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2019074738 | 2019-04-10 | ||
| JP2019074738 | 2019-04-10 | ||
| PCT/JP2020/015904 WO2020209318A1 (ja) | 2019-04-10 | 2020-04-09 | Ｆｃ領域改変抗体の精製方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JPWO2020209318A1 JPWO2020209318A1 (https=) | 2020-10-15 |
| JPWO2020209318A5 true JPWO2020209318A5 (https=) | 2023-03-29 |
| JP7583411B2 JP7583411B2 (ja) | 2024-11-14 |
Family
ID=72752051
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021513692A Active JP7583411B2 (ja) | 2019-04-10 | 2020-04-09 | Ｆｃ領域改変抗体の精製方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20220213140A1 (https=) |
| EP (1) | EP3954696A4 (https=) |
| JP (1) | JP7583411B2 (https=) |
| KR (1) | KR20210149779A (https=) |
| CN (1) | CN113906042A (https=) |
| AU (1) | AU2020273072B2 (https=) |
| BR (1) | BR112021020204A2 (https=) |
| CA (1) | CA3136398A1 (https=) |
| IL (1) | IL286982A (https=) |
| MX (1) | MX2021012251A (https=) |
| SG (1) | SG11202110986YA (https=) |
| TW (2) | TW202509054A (https=) |
| WO (1) | WO2020209318A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2892925T3 (es) | 2006-03-31 | 2022-02-07 | Chugai Pharmaceutical Co Ltd | Métodos para controlar la farmacocinética en sangre de anticuerpos |
| CN101874042B9 (zh) | 2007-09-26 | 2019-01-01 | 中外制药株式会社 | 利用cdr的氨基酸取代来改变抗体等电点的方法 |
| KR102057826B1 (ko) | 2008-04-11 | 2019-12-20 | 추가이 세이야쿠 가부시키가이샤 | 복수 분자의 항원에 반복 결합하는 항원 결합 분자 |
| TWI812066B (zh) | 2010-11-30 | 2023-08-11 | 日商中外製藥股份有限公司 | 具有鈣依存性的抗原結合能力之抗體 |
| KR101860280B1 (ko) | 2014-12-19 | 2018-05-21 | 추가이 세이야쿠 가부시키가이샤 | 항-마이오스타틴 항체, 변이체 Fc 영역을 함유하는 폴리펩타이드, 및 사용 방법 |
| CN114773470A (zh) | 2015-02-05 | 2022-07-22 | 中外制药株式会社 | 包含离子浓度依赖性的抗原结合结构域的抗体，fc区变体，il-8-结合抗体及其应用 |
| US11359009B2 (en) | 2015-12-25 | 2022-06-14 | Chugai Seiyaku Kabushiki Kaisha | Anti-myostatin antibodies and methods of use |
| TWI693940B (zh) | 2016-08-05 | 2020-05-21 | 日商中外製藥股份有限公司 | Ｉｌ-８相關疾病之治療用或預防用組成物 |
| CN115850408A (zh) * | 2022-09-01 | 2023-03-28 | 西安蓝晓科技新材料股份有限公司 | 一种多肽、融合型多聚体蛋白质及其用途 |
Family Cites Families (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
| EP0585287B1 (en) | 1990-07-10 | 1999-10-13 | Cambridge Antibody Technology Limited | Methods for producing members of specific binding pairs |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| ATE300615T1 (de) | 1990-08-29 | 2005-08-15 | Genpharm Int | Transgene mäuse fähig zur produktion heterologer antikörper |
| GB9022547D0 (en) | 1990-10-17 | 1990-11-28 | Wellcome Found | Purified immunoglobulin |
| EP0628639B1 (en) | 1991-04-25 | 1999-06-23 | Chugai Seiyaku Kabushiki Kaisha | Reconstituted human antibody against human interleukin 6 receptor |
| AU665025B2 (en) | 1991-09-23 | 1995-12-14 | Cambridge Antibody Technology Limited | Production of chimeric antibodies - a combinatorial approach |
| ES2341666T3 (es) | 1991-12-02 | 2010-06-24 | Medimmune Limited | Produccion de autoanticuerpos de repertorios de segmentos de anticue rpos expresados en la superficie de fagos. |
| CA2124967C (en) | 1991-12-17 | 2008-04-08 | Nils Lonberg | Transgenic non-human animals capable of producing heterologous antibodies |
| DE69333823T2 (de) | 1992-03-24 | 2006-05-04 | Cambridge Antibody Technology Ltd., Melbourn | Verfahren zur herstellung von gliedern von spezifischen bindungspaaren |
| NZ255101A (en) | 1992-07-24 | 1997-08-22 | Cell Genesys Inc | A yeast artificial chromosome (yac) vector containing an hprt minigene expressible in murine stem cells and genetically modified rodent therefor |
| CA2161351C (en) | 1993-04-26 | 2010-12-21 | Nils Lonberg | Transgenic non-human animals capable of producing heterologous antibodies |
| GB9313509D0 (en) | 1993-06-30 | 1993-08-11 | Medical Res Council | Chemisynthetic libraries |
| EP0731842A1 (en) | 1993-12-03 | 1996-09-18 | Medical Research Council | Recombinant binding proteins and peptides |
| CA2194907A1 (en) | 1994-07-13 | 1996-02-01 | Kouji Matsushima | Reshaped human antibody against human interleukin-8 |
| CA2219361C (en) | 1995-04-27 | 2012-02-28 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| EP0823941A4 (en) | 1995-04-28 | 2001-09-19 | Abgenix Inc | HUMAN ANTIBODIES DERIVED FROM IMMUNIZED XENO MOUSES |
| CN103172731A (zh) | 2004-07-15 | 2013-06-26 | 赞科股份有限公司 | 优化的Fc变体 |
| DK1817340T3 (da) | 2004-11-12 | 2012-08-13 | Xencor Inc | Fc-varianter med ændret binding til fcrn |
| CN103555733A (zh) | 2005-01-05 | 2014-02-05 | F-星生物技术研究与开发有限公司 | 分子中互补决定区以外的区域中工程改造了的具有结合特性的合成免疫球蛋白结构域 |
| WO2007097361A1 (ja) * | 2006-02-21 | 2007-08-30 | Protenova Co., Ltd. | イムノグロブリン親和性リガンド |
| JP4179517B2 (ja) | 2006-02-21 | 2008-11-12 | プロテノバ株式会社 | イムノグロブリン親和性リガンド |
| ES2892925T3 (es) | 2006-03-31 | 2022-02-07 | Chugai Pharmaceutical Co Ltd | Métodos para controlar la farmacocinética en sangre de anticuerpos |
| AU2008304748C1 (en) | 2007-09-26 | 2014-06-12 | Chugai Seiyaku Kabushiki Kaisha | Modified antibody constant region |
| RU2529951C2 (ru) | 2007-12-26 | 2014-10-10 | Ксенкор, Инк. | ВАРИАНТЫ Fc С ИЗМЕНЕННЫМ СВЯЗЫВАНИЕМ C FcRn |
| KR102057826B1 (ko) | 2008-04-11 | 2019-12-20 | 추가이 세이야쿠 가부시키가이샤 | 복수 분자의 항원에 반복 결합하는 항원 결합 분자 |
| JP5229888B2 (ja) * | 2008-09-30 | 2013-07-03 | 独立行政法人産業技術総合研究所 | 弱酸性域での易解離性を向上したプロテインａ変異型タンパク質及び抗体捕捉剤 |
| TWI667346B (zh) | 2010-03-30 | 2019-08-01 | 中外製藥股份有限公司 | 促進抗原消失之具有經修飾的FcRn親和力之抗體 |
| EP3029066B1 (en) | 2010-07-29 | 2019-02-20 | Xencor, Inc. | Antibodies with modified isoelectric points |
| TWI812066B (zh) | 2010-11-30 | 2023-08-11 | 日商中外製藥股份有限公司 | 具有鈣依存性的抗原結合能力之抗體 |
| WO2012132067A1 (ja) | 2011-03-30 | 2012-10-04 | 中外製薬株式会社 | 抗原結合分子の血漿中滞留性と免疫原性を改変する方法 |
| WO2012133349A1 (ja) * | 2011-03-25 | 2012-10-04 | 株式会社カネカ | アフィニティー分離マトリックス用タンパク質 |
| TW201817744A (zh) | 2011-09-30 | 2018-05-16 | 日商中外製藥股份有限公司 | 具有促進抗原清除之ＦｃＲｎ結合域的治療性抗原結合分子 |
| EP3680251A1 (en) | 2011-09-30 | 2020-07-15 | Chugai Seiyaku Kabushiki Kaisha | Antigen-binding molecules for promoting elimination of antigens |
| EP2857419B1 (en) | 2012-05-30 | 2021-01-13 | Chugai Seiyaku Kabushiki Kaisha | Antigen-binding molecule for eliminating aggregated antigens |
| EP3795215A1 (en) | 2012-05-30 | 2021-03-24 | Chugai Seiyaku Kabushiki Kaisha | Target tissue-specific antigen-binding molecule |
| US20160031985A1 (en) | 2013-03-15 | 2016-02-04 | Katherine S. Bowdish | Charge-engineered antibodies or compositions of penetration-enhanced targeting proteins and methods of use |
| JP6153801B2 (ja) | 2013-07-23 | 2017-06-28 | 旭化成ホームズ株式会社 | ノズル |
| WO2015034000A1 (ja) * | 2013-09-04 | 2015-03-12 | プロテノバ株式会社 | イムノグロブリン結合ドメイン多量体 |
| JP2015185254A (ja) | 2014-03-20 | 2015-10-22 | 日立マクセル株式会社 | 非水電解質二次電池 |
| KR101860280B1 (ko) * | 2014-12-19 | 2018-05-21 | 추가이 세이야쿠 가부시키가이샤 | 항-마이오스타틴 항체, 변이체 Fc 영역을 함유하는 폴리펩타이드, 및 사용 방법 |
| TWI605057B (zh) * | 2015-12-18 | 2017-11-11 | 中外製藥股份有限公司 | 抗肌抑素抗體、含變異ｆｃ區之多肽及使用方法 |
-
2020
- 2020-04-09 JP JP2021513692A patent/JP7583411B2/ja active Active
- 2020-04-09 EP EP20787324.1A patent/EP3954696A4/en active Pending
- 2020-04-09 US US17/602,196 patent/US20220213140A1/en active Pending
- 2020-04-09 TW TW113143764A patent/TW202509054A/zh unknown
- 2020-04-09 KR KR1020217035897A patent/KR20210149779A/ko active Pending
- 2020-04-09 CN CN202080034720.3A patent/CN113906042A/zh active Pending
- 2020-04-09 WO PCT/JP2020/015904 patent/WO2020209318A1/ja not_active Ceased
- 2020-04-09 AU AU2020273072A patent/AU2020273072B2/en active Active
- 2020-04-09 TW TW109111941A patent/TW202104244A/zh unknown
- 2020-04-09 CA CA3136398A patent/CA3136398A1/en active Pending
- 2020-04-09 MX MX2021012251A patent/MX2021012251A/es unknown
- 2020-04-09 SG SG11202110986YA patent/SG11202110986YA/en unknown
- 2020-04-09 BR BR112021020204A patent/BR112021020204A2/pt unknown
-
2021
- 2021-10-05 IL IL286982A patent/IL286982A/en unknown
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