JPWO2020209318A5 - - Google Patents
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- JPWO2020209318A5 JPWO2020209318A5 JP2021513692A JP2021513692A JPWO2020209318A5 JP WO2020209318 A5 JPWO2020209318 A5 JP WO2020209318A5 JP 2021513692 A JP2021513692 A JP 2021513692A JP 2021513692 A JP2021513692 A JP 2021513692A JP WO2020209318 A5 JPWO2020209318 A5 JP WO2020209318A5
- Authority
- JP
- Japan
- Prior art keywords
- domain
- amino acid
- residue
- igg antibody
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2019074738 | 2019-04-10 | ||
| JP2019074738 | 2019-04-10 | ||
| PCT/JP2020/015904 WO2020209318A1 (ja) | 2019-04-10 | 2020-04-09 | Ｆｃ領域改変抗体の精製方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JPWO2020209318A1 JPWO2020209318A1 (https=) | 2020-10-15 |
| JPWO2020209318A5 true JPWO2020209318A5 (https=) | 2023-03-29 |
| JP7583411B2 JP7583411B2 (ja) | 2024-11-14 |
Family
ID=72752051
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021513692A Active JP7583411B2 (ja) | 2019-04-10 | 2020-04-09 | Ｆｃ領域改変抗体の精製方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20220213140A1 (https=) |
| EP (1) | EP3954696A4 (https=) |
| JP (1) | JP7583411B2 (https=) |
| KR (1) | KR20210149779A (https=) |
| CN (1) | CN113906042A (https=) |
| AU (1) | AU2020273072B2 (https=) |
| BR (1) | BR112021020204A2 (https=) |
| CA (1) | CA3136398A1 (https=) |
| IL (1) | IL286982A (https=) |
| MX (1) | MX2021012251A (https=) |
| SG (1) | SG11202110986YA (https=) |
| TW (2) | TW202104244A (https=) |
| WO (1) | WO2020209318A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104761637B (zh) | 2006-03-31 | 2021-10-15 | 中外制药株式会社 | 调控抗体血液动力学的方法 |
| ES2595638T3 (es) | 2007-09-26 | 2017-01-02 | Chugai Seiyaku Kabushiki Kaisha | Método para modificar el punto isoeléctrico de un anticuerpo mediante la sustitución de aminoácidos en una CDR |
| KR102057826B1 (ko) | 2008-04-11 | 2019-12-20 | 추가이 세이야쿠 가부시키가이샤 | 복수 분자의 항원에 반복 결합하는 항원 결합 분자 |
| EP2647706B1 (en) | 2010-11-30 | 2023-05-17 | Chugai Seiyaku Kabushiki Kaisha | Antigen-binding molecule capable of binding to plurality of antigen molecules repeatedly |
| KR101860280B1 (ko) | 2014-12-19 | 2018-05-21 | 추가이 세이야쿠 가부시키가이샤 | 항-마이오스타틴 항체, 변이체 Fc 영역을 함유하는 폴리펩타이드, 및 사용 방법 |
| KR102605798B1 (ko) | 2015-02-05 | 2023-11-23 | 추가이 세이야쿠 가부시키가이샤 | 이온 농도 의존적 항원 결합 도메인을 포함하는 항체, Fc 영역 개변체, IL-8에 결합하는 항체, 및 그들의 사용 |
| WO2017110981A1 (en) | 2015-12-25 | 2017-06-29 | Chugai Seiyaku Kabushiki Kaisha | Anti-myostatin antibodies and methods of use |
| EP3494991A4 (en) | 2016-08-05 | 2020-07-29 | Chugai Seiyaku Kabushiki Kaisha | COMPOSITION FOR THE PROPHYLAXIS OR TREATMENT OF IL-8 RELATED DISEASES |
| CN115850408A (zh) * | 2022-09-01 | 2023-03-28 | 西安蓝晓科技新材料股份有限公司 | 一种多肽、融合型多聚体蛋白质及其用途 |
Family Cites Families (42)
| Publication number | Priority date | Publication date | Assignee | Title |
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| GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
| WO1996033735A1 (en) | 1995-04-27 | 1996-10-31 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| DK0585287T3 (da) | 1990-07-10 | 2000-04-17 | Cambridge Antibody Tech | Fremgangsmåde til fremstilling af specifikke bindingsparelementer |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| ATE158021T1 (de) | 1990-08-29 | 1997-09-15 | Genpharm Int | Produktion und nützung nicht-menschliche transgentiere zur produktion heterologe antikörper |
| WO1993012227A1 (en) | 1991-12-17 | 1993-06-24 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| GB9022547D0 (en) | 1990-10-17 | 1990-11-28 | Wellcome Found | Purified immunoglobulin |
| US5795965A (en) | 1991-04-25 | 1998-08-18 | Chugai Seiyaku Kabushiki Kaisha | Reshaped human to human interleukin-6 receptor |
| EP0605522B1 (en) | 1991-09-23 | 1999-06-23 | Medical Research Council | Methods for the production of humanized antibodies |
| PT1024191E (pt) | 1991-12-02 | 2008-12-22 | Medical Res Council | Produção de auto-anticorpos a partir de reportórios de segmentos de anticorpo e exibidos em fagos |
| CA2131151A1 (en) | 1992-03-24 | 1994-09-30 | Kevin S. Johnson | Methods for producing members of specific binding pairs |
| ES2301158T3 (es) | 1992-07-24 | 2008-06-16 | Amgen Fremont Inc. | Produccion de anticuerpos xenogenicos. |
| JPH08509612A (ja) | 1993-04-26 | 1996-10-15 | ジェンファーム インターナショナル インコーポレイテッド | 異種抗体を産生することができるトランスジェニック非ヒト動物 |
| GB9313509D0 (en) | 1993-06-30 | 1993-08-11 | Medical Res Council | Chemisynthetic libraries |
| WO1995015388A1 (en) | 1993-12-03 | 1995-06-08 | Medical Research Council | Recombinant binding proteins and peptides |
| DE69535243T2 (de) | 1994-07-13 | 2007-05-10 | Chugai Seiyaku K.K. | Gegen menschliches interleukin-8 gerichteter, rekonstituierter menschlicher antikörper |
| WO1996034096A1 (en) | 1995-04-28 | 1996-10-31 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| EP2471813B1 (en) | 2004-07-15 | 2014-12-31 | Xencor, Inc. | Optimized Fc variants |
| AU2005304624B2 (en) | 2004-11-12 | 2010-10-07 | Xencor, Inc. | Fc variants with altered binding to FcRn |
| EP1699826B1 (en) | 2005-01-05 | 2009-03-11 | f-star Biotechnologische Forschungs- und Entwicklungsges.m.b.H. | Synthetic immunoglobulin domains with binding properties engineered in regions of the molecule different from the complementarity determining regions |
| JP4179517B2 (ja) * | 2006-02-21 | 2008-11-12 | プロテノバ株式会社 | イムノグロブリン親和性リガンド |
| WO2007097361A1 (ja) * | 2006-02-21 | 2007-08-30 | Protenova Co., Ltd. | イムノグロブリン親和性リガンド |
| CN104761637B (zh) | 2006-03-31 | 2021-10-15 | 中外制药株式会社 | 调控抗体血液动力学的方法 |
| KR101680906B1 (ko) | 2007-09-26 | 2016-11-30 | 추가이 세이야쿠 가부시키가이샤 | 항체 정상영역 개변체 |
| HRP20150279T1 (hr) | 2007-12-26 | 2015-05-08 | Xencor, Inc. | Fc inaäśice s promijenjenim vezanjem na fcrn |
| KR102057826B1 (ko) | 2008-04-11 | 2019-12-20 | 추가이 세이야쿠 가부시키가이샤 | 복수 분자의 항원에 반복 결합하는 항원 결합 분자 |
| JP5229888B2 (ja) * | 2008-09-30 | 2013-07-03 | 独立行政法人産業技術総合研究所 | 弱酸性域での易解離性を向上したプロテインａ変異型タンパク質及び抗体捕捉剤 |
| TWI667257B (zh) | 2010-03-30 | 2019-08-01 | 中外製藥股份有限公司 | 促進抗原消失之具有經修飾的ＦｃＲｎ親和力之抗體 |
| AU2011283694B2 (en) | 2010-07-29 | 2017-04-13 | Xencor, Inc. | Antibodies with modified isoelectric points |
| EP2647706B1 (en) | 2010-11-30 | 2023-05-17 | Chugai Seiyaku Kabushiki Kaisha | Antigen-binding molecule capable of binding to plurality of antigen molecules repeatedly |
| WO2012132067A1 (ja) | 2011-03-30 | 2012-10-04 | 中外製薬株式会社 | 抗原結合分子の血漿中滞留性と免疫原性を改変する方法 |
| EP2690173B1 (en) * | 2011-03-25 | 2019-07-03 | Kaneka Corporation | Protein for affinity-separation matrix |
| TW201817744A (zh) | 2011-09-30 | 2018-05-16 | 日商中外製藥股份有限公司 | 具有促進抗原清除之ＦｃＲｎ結合域的治療性抗原結合分子 |
| RU2014117505A (ru) | 2011-09-30 | 2015-11-10 | Чугаи Сейяку Кабусики Кайся | Антигенсвязывающая молекула для ускорения удаления антигенов |
| EP2857419B1 (en) | 2012-05-30 | 2021-01-13 | Chugai Seiyaku Kabushiki Kaisha | Antigen-binding molecule for eliminating aggregated antigens |
| WO2013180200A1 (ja) | 2012-05-30 | 2013-12-05 | 中外製薬株式会社 | 標的組織特異的抗原結合分子 |
| WO2014145159A2 (en) | 2013-03-15 | 2014-09-18 | Permeon Biologics, Inc. | Charge-engineered antibodies or compositions of penetration-enhanced targeting proteins and methods of use |
| JP6153801B2 (ja) | 2013-07-23 | 2017-06-28 | 旭化成ホームズ株式会社 | ノズル |
| JP6456831B2 (ja) * | 2013-09-04 | 2019-01-23 | プロテノバ株式会社 | イムノグロブリン結合ドメイン多量体 |
| JP2015185254A (ja) | 2014-03-20 | 2015-10-22 | 日立マクセル株式会社 | 非水電解質二次電池 |
| KR101860280B1 (ko) * | 2014-12-19 | 2018-05-21 | 추가이 세이야쿠 가부시키가이샤 | 항-마이오스타틴 항체, 변이체 Fc 영역을 함유하는 폴리펩타이드, 및 사용 방법 |
| AR107078A1 (es) * | 2015-12-18 | 2018-03-21 | Chugai Pharmaceutical Co Ltd | Anticuerpo antimiostatina, polipéptidos que contienen regiones fc variantes así como métodos de uso |
-
2020
- 2020-04-09 US US17/602,196 patent/US20220213140A1/en active Pending
- 2020-04-09 BR BR112021020204A patent/BR112021020204A2/pt unknown
- 2020-04-09 EP EP20787324.1A patent/EP3954696A4/en active Pending
- 2020-04-09 TW TW109111941A patent/TW202104244A/zh unknown
- 2020-04-09 TW TW113143764A patent/TW202509054A/zh unknown
- 2020-04-09 KR KR1020217035897A patent/KR20210149779A/ko active Pending
- 2020-04-09 JP JP2021513692A patent/JP7583411B2/ja active Active
- 2020-04-09 AU AU2020273072A patent/AU2020273072B2/en active Active
- 2020-04-09 WO PCT/JP2020/015904 patent/WO2020209318A1/ja not_active Ceased
- 2020-04-09 SG SG11202110986YA patent/SG11202110986YA/en unknown
- 2020-04-09 CN CN202080034720.3A patent/CN113906042A/zh active Pending
- 2020-04-09 CA CA3136398A patent/CA3136398A1/en active Pending
- 2020-04-09 MX MX2021012251A patent/MX2021012251A/es unknown
-
2021
- 2021-10-05 IL IL286982A patent/IL286982A/en unknown
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