JPWO2022059775A1 - - Google Patents
Info
- Publication number
- JPWO2022059775A1 JPWO2022059775A1 JP2022550627A JP2022550627A JPWO2022059775A1 JP WO2022059775 A1 JPWO2022059775 A1 JP WO2022059775A1 JP 2022550627 A JP2022550627 A JP 2022550627A JP 2022550627 A JP2022550627 A JP 2022550627A JP WO2022059775 A1 JPWO2022059775 A1 JP WO2022059775A1
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
- A61K31/355—Tocopherols, e.g. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/665—Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7016—Disaccharides, e.g. lactose, lactulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/702—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7032—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a polyol, i.e. compounds having two or more free or esterified hydroxy groups, including the hydroxy group involved in the glycosidic linkage, e.g. monoglucosyldiacylglycerides, lactobionic acid, gangliosides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2020156459 | 2020-09-17 | ||
| PCT/JP2021/034285 WO2022059775A1 (ja) | 2020-09-17 | 2021-09-17 | オートファジー活性化剤 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPWO2022059775A1 true JPWO2022059775A1 (https=) | 2022-03-24 |
Family
ID=80776133
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022550627A Pending JPWO2022059775A1 (https=) | 2020-09-17 | 2021-09-17 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20230355646A1 (https=) |
| EP (1) | EP4215199A4 (https=) |
| JP (1) | JPWO2022059775A1 (https=) |
| KR (1) | KR20230054431A (https=) |
| CN (1) | CN116322705B (https=) |
| WO (1) | WO2022059775A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2022159546A (ja) * | 2022-08-22 | 2022-10-17 | 功 加治佐 | オートファジーとサーチュインとｉＰＳウイルス運び屋若返り不老不死薬１０ |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20040065864A (ko) * | 2003-01-16 | 2004-07-23 | 주식회사 엘지생활건강 | 피부알러지 완화 및 예방용 조성물 |
| WO2014181716A1 (ja) * | 2013-05-10 | 2014-11-13 | 昭和電工株式会社 | 糖化反応抑制剤 |
| JP2018058769A (ja) * | 2016-09-30 | 2018-04-12 | 小林製薬株式会社 | 医薬組成物 |
| JP2020125246A (ja) * | 2019-02-01 | 2020-08-20 | 花王株式会社 | 認知機能障害改善剤 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5944375A (ja) | 1982-09-06 | 1984-03-12 | Senjiyu Seiyaku Kk | α−トコフエロ−ルリン酸エステルの安定な水溶液 |
| US4654869A (en) | 1985-09-11 | 1987-03-31 | Itt Corporation | Information collecting and forwarding apparatus |
| JPH0649715B2 (ja) | 1987-02-10 | 1994-06-29 | 栗田工業株式会社 | 末端にイノシト−ル残基を結合したグルコオリゴ糖およびその製造方法 |
| JPH0730066B2 (ja) | 1988-03-09 | 1995-04-05 | 株式会社日本ハイポックス | アスコルビン酸誘導体及びアスコルビン酸誘導体からなる抗酸化剤 |
| JP2747001B2 (ja) | 1989-04-18 | 1998-05-06 | 昭和電工株式会社 | Ｌ―アスコルビン酸―２―リン酸エステル類の製造法 |
| JP2926412B2 (ja) | 1989-05-19 | 1999-07-28 | 株式会社林原生物化学研究所 | α―グリコシル―Ｌ―アスコルビン酸とその製造方法並びに用途 |
| JPH06298783A (ja) | 1993-03-31 | 1994-10-25 | Mitsui Toatsu Chem Inc | 新規なグリコシドの製造法 |
| JP2705512B2 (ja) | 1993-06-04 | 1998-01-28 | 昭和電工株式会社 | Ｌ−アスコルビン酸−２−リン酸エステルの製造方法 |
| JPH08134055A (ja) | 1994-11-08 | 1996-05-28 | Nippon High Potsukusu:Kk | ３−ｏ−置換アスコルビン酸の製造方法 |
| JPH0914705A (ja) | 1995-06-29 | 1997-01-17 | Hitachi Ltd | 流体移送装置 |
| WO2010119955A1 (ja) * | 2009-04-17 | 2010-10-21 | ロート製薬株式会社 | アドバンスド・グリケーション・エンド・プロダクツの蓄積による肌の老化の予防、抑制、又は改善剤 |
| JP5735254B2 (ja) * | 2009-10-22 | 2015-06-17 | 花王株式会社 | 経口紫外線抵抗性向上剤 |
| WO2013018779A1 (ja) | 2011-08-01 | 2013-02-07 | 株式会社林原 | α－グルコシルヘスペリジンの結晶とその用途 |
| JP6116869B2 (ja) * | 2012-01-17 | 2017-04-19 | 花王株式会社 | 経口紫外線抵抗性向上剤 |
| WO2016076310A1 (ja) | 2014-11-10 | 2016-05-19 | 昭和電工株式会社 | 保湿剤 |
| KR20170141705A (ko) | 2015-04-08 | 2017-12-26 | 바이오멘딕스, 엘엘씨 | 상처 치유를 조절하기 위한 제형 및 방법 |
| JP6740354B2 (ja) | 2015-10-05 | 2020-08-12 | ザ トラスティーズ オブ コロンビア ユニバーシティー イン ザ シティー オブ ニューヨーク | オートファジーの流れ及びホスホリパーゼｄ及びタウを含むタンパク質凝集体のクリアランスの活性化剤ならびにタンパク質症の治療方法 |
| JP7136765B2 (ja) | 2017-03-24 | 2022-09-13 | 株式会社林原 | オートファジー誘導剤とその用途 |
| CA3059461C (en) * | 2017-04-12 | 2023-08-15 | Glovia Company Limited | Composition for treatment and/or prevention of alzheimer's disease |
| CN111051519B (zh) | 2017-09-04 | 2024-04-26 | 株式会社力森诺科 | 肌醇衍生物的混合物 |
| CN110024706A (zh) | 2019-03-25 | 2019-07-19 | 嘉兴市顶升杯业有限公司 | 一种新型宠物碗 |
-
2021
- 2021-09-17 WO PCT/JP2021/034285 patent/WO2022059775A1/ja not_active Ceased
- 2021-09-17 KR KR1020237009525A patent/KR20230054431A/ko active Pending
- 2021-09-17 JP JP2022550627A patent/JPWO2022059775A1/ja active Pending
- 2021-09-17 CN CN202180071407.1A patent/CN116322705B/zh active Active
- 2021-09-17 EP EP21869457.8A patent/EP4215199A4/en not_active Withdrawn
- 2021-09-17 US US18/026,057 patent/US20230355646A1/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20040065864A (ko) * | 2003-01-16 | 2004-07-23 | 주식회사 엘지생활건강 | 피부알러지 완화 및 예방용 조성물 |
| WO2014181716A1 (ja) * | 2013-05-10 | 2014-11-13 | 昭和電工株式会社 | 糖化反応抑制剤 |
| JP2018058769A (ja) * | 2016-09-30 | 2018-04-12 | 小林製薬株式会社 | 医薬組成物 |
| JP2020125246A (ja) * | 2019-02-01 | 2020-08-20 | 花王株式会社 | 認知機能障害改善剤 |
Non-Patent Citations (4)
| Title |
|---|
| ALDONZA, M. B. D. ET AL.: "Suppression of MAPK Signaling and Reversal of mTOR-Dependent MDR1-Associated Multidrug Resistance by", PLOS ONE, vol. 10(6), JPN6021041542, 2015, pages 0127841 - 1, ISSN: 0005759836 * |
| RANJITHA, C. J. ET AL.: "Neuroprotective Effect of Hesperidin Methyl Chalcone against Aluminium Chloride Induced Alzheimer's", INTERNATIONAL JOURNAL OF PHARMACY & PHARMACEUTICAL RESEARCH, vol. 19(4), JPN6021041540, 30 November 2020 (2020-11-30), pages 114 - 136, ISSN: 0005759837 * |
| SAIPRASAD, G ET AL.: "Hesperidin induces apoptosis and triggers autophagic markers through inhibition of Aurora-A mediated", EUROPEAN JOURNAL OF CANCER, vol. 50, JPN6021041538, 2014, pages 2489 - 2507, ISSN: 0005759835 * |
| ZHU, B. ET AL.: "Autophagic activation may be involved in the mechanism of hesrperidin's therapeutic effects on cogni", JOURNAL OF THE NEUROLOGICAL SCIENCES, vol. 351, JPN6021041537, 2015, pages 202 - 203, ISSN: 0005759834 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN116322705B (zh) | 2025-10-10 |
| KR20230054431A (ko) | 2023-04-24 |
| WO2022059775A1 (ja) | 2022-03-24 |
| US20230355646A1 (en) | 2023-11-09 |
| EP4215199A4 (en) | 2024-10-09 |
| EP4215199A1 (en) | 2023-07-26 |
| CN116322705A (zh) | 2023-06-23 |
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