|
CA2795349C
(en)
|
2010-04-15 |
2016-11-29 |
Seattle Genetics, Inc. |
Targeted pyrrolobenzodiazepine conjugates
|
|
IN2014DN06806A
(https=)
|
2012-02-10 |
2015-05-22 |
Univ Maryland |
|
|
US20130309223A1
(en)
|
2012-05-18 |
2013-11-21 |
Seattle Genetics, Inc. |
CD33 Antibodies And Use Of Same To Treat Cancer
|
|
ES2773710T3
(es)
|
2012-10-11 |
2020-07-14 |
Daiichi Sankyo Co Ltd |
Enlazadores para conjugados de anticuerpo - fármaco
|
|
US9695212B2
(en)
|
2012-12-13 |
2017-07-04 |
Aduro Biotech, Inc. |
Compositions comprising cyclic purine dinucleotides having defined stereochemistries and methods for their preparation and use
|
|
EP2934598B1
(en)
|
2012-12-19 |
2018-04-18 |
Board Of Regents, The University Of Texas System |
Pharmaceutical targeting of a mammalian cyclic di-nucleotide signaling pathway
|
|
ES2731681T3
(es)
|
2013-02-22 |
2019-11-18 |
Abbvie Stemcentrx Llc |
Conjugados de anticuerpo anti-DLL3 y PBD y usos de los mismos
|
|
US9840533B2
(en)
|
2013-04-29 |
2017-12-12 |
Memorial Sloan Kettering Cancer Center |
Compositions and methods for altering second messenger signaling
|
|
PE20160080A1
(es)
|
2013-05-18 |
2016-02-21 |
Aduro Biotech Inc |
Composiciones y metodos para activar la senalizacion que depende del estimulador del gen de interferon
|
|
WO2014189806A1
(en)
|
2013-05-18 |
2014-11-27 |
Aduro Biotech, Inc. |
Compositions and methods for inhibiting "stimulator of interferon gene" dependent signalling
|
|
KR20160047567A
(ko)
|
2013-08-28 |
2016-05-02 |
스템센트알엑스 인코포레이티드 |
조작된 항-dll3 접합체 및 사용 방법
|
|
WO2015052534A1
(en)
|
2013-10-11 |
2015-04-16 |
Spirogen Sàrl |
Pyrrolobenzodiazepine-antibody conjugates
|
|
GB201317982D0
(en)
|
2013-10-11 |
2013-11-27 |
Spirogen Sarl |
Pyrrolobenzodiazepines and conjugates thereof
|
|
GB201317981D0
(en)
|
2013-10-11 |
2013-11-27 |
Spirogen Sarl |
Pyrrolobenzodiazepines and conjugates thereof
|
|
WO2015074145A1
(en)
|
2013-11-22 |
2015-05-28 |
Brock University |
Use of fluorinated cyclic dinucleotides as oral vaccine adjuvants
|
|
KR102337414B1
(ko)
|
2013-12-16 |
2021-12-10 |
제넨테크, 인크. |
펩타이드 모방체 화합물 및 이의 항체-약물 컨쥬게이트
|
|
CR20160564A
(es)
|
2014-06-04 |
2017-01-20 |
Glaxosmithkline Ip Dev Ltd |
Dinucleótidos cíclicos como moduladores de sting
|
|
DE102014214408A1
(de)
|
2014-07-23 |
2016-01-28 |
Wacker Chemie Ag |
Härtbare Organopolysiloxanzusammensetzungen
|
|
BR102014018190B1
(pt)
|
2014-07-24 |
2020-10-20 |
Fabio Eduardo Sabonge Cunha |
suporte para placa de sinalização vertical
|
|
WO2016036804A1
(en)
|
2014-09-03 |
2016-03-10 |
Immunogen, Inc. |
Cytotoxic benzodiazepine derivatives
|
|
EP4530348A3
(en)
|
2014-12-15 |
2025-08-06 |
Basf Se |
Detergent composition comprising subtilase variants
|
|
EA035817B1
(ru)
|
2015-03-10 |
2020-08-14 |
Адуро Байотек, Инк. |
Композиции и способы для активации сигналинга, зависимого от "гена стимулятора интерферона"
|
|
SMT202000614T1
(it)
|
2015-06-29 |
2021-01-05 |
Immunogen Inc |
Coniugati di anticorpi ingegnerizzati con cisteina
|
|
JP6744738B2
(ja)
*
|
2015-06-29 |
2020-08-19 |
公益財団法人野口研究所 |
グライコシンターゼ
|
|
SG10202005460RA
(en)
|
2015-06-30 |
2020-07-29 |
Seattle Genetics Inc |
Anti-ntb-a antibodies and related compositions and methods
|
|
CN108026518B
(zh)
*
|
2015-07-16 |
2022-09-06 |
第一三共株式会社 |
新型endos突变型酶
|
|
GB201513607D0
(en)
|
2015-07-31 |
2015-09-16 |
Feingold Jay M |
Pyrrolobenzodiazepine-antibody conjugates
|
|
KR102222186B1
(ko)
|
2015-08-13 |
2021-03-03 |
머크 샤프 앤드 돔 코포레이션 |
Sting 효능제로서 시클릭 디-뉴클레오티드 화합물
|
|
JP2018534295A
(ja)
|
2015-10-28 |
2018-11-22 |
アドゥロ バイオテック,インク. |
「インターフェロン遺伝子刺激因子」依存性シグナル伝達を活性化するための組成物および方法
|
|
CN107849084B
(zh)
|
2015-12-03 |
2021-09-14 |
葛兰素史密斯克莱知识产权发展有限公司 |
作为sting调节剂的环状嘌呤二核苷酸
|
|
DE212016000029U1
(de)
|
2015-12-07 |
2017-07-30 |
Opi Vi - Ip Holdco Llc |
Zusammensetzungen von Antikörperkonstrukt-Agonist-Konjugaten
|
|
KR102789862B1
(ko)
|
2016-01-11 |
2025-04-03 |
인네이트 튜머 이뮤니티, 인코포레이티드 |
Sting 활성과 연관된 상태 예컨대 암의 치료를 위한 시클릭 디뉴클레오티드
|
|
WO2017124084A1
(en)
|
2016-01-15 |
2017-07-20 |
University Of Maryland, College Park |
Endo-s2 mutants as glycosynthases, method of making and use for glycoengineering of glycoproteins
|
|
NZ746112A
(en)
|
2016-03-18 |
2023-01-27 |
Immune Sensor Llc |
Cyclic di-nucleotide compounds and methods of use
|
|
JP2019510802A
(ja)
|
2016-04-07 |
2019-04-18 |
グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited |
タンパク質調節物質として有用な複素環アミド
|
|
PT3440076T
(pt)
|
2016-04-07 |
2022-07-29 |
Glaxosmithkline Ip Dev Ltd |
Amidas heterocíclicas úteis como modeladores de proteína
|
|
WO2018003983A1
(ja)
|
2016-07-01 |
2018-01-04 |
第一三共株式会社 |
hANP-Fc含有分子コンジュゲート
|
|
EP3507367A4
(en)
|
2016-07-05 |
2020-03-25 |
Aduro BioTech, Inc. |
CYCLIC DINUCLEOTID COMPOUNDS WITH INCLUDED NUCLEIC ACIDS AND USES THEREOF
|
|
IL264049B2
(en)
|
2016-07-06 |
2023-11-01 |
Sperovie Biosciences Inc |
Compounds, preparations and methods for treating the disease
|
|
WO2018039373A1
(en)
|
2016-08-24 |
2018-03-01 |
Cho Pharma Inc |
Endoglycosidase mutants for glycoprotein remodeling and methods of using it
|
|
US20190345191A1
(en)
|
2016-08-31 |
2019-11-14 |
Innate Tumor Immunity, Inc. |
Cyclic dinucleotide analogs for treating conditions associated with sting (stimulator of interferon genes) activity
|
|
US10537590B2
(en)
|
2016-09-30 |
2020-01-21 |
Boehringer Ingelheim International Gmbh |
Cyclic dinucleotide compounds
|
|
PT3523287T
(pt)
|
2016-10-04 |
2021-10-06 |
Merck Sharp & Dohme |
Compostos de benzo[b]tiofeno como agonistas de sting
|
|
US11001605B2
(en)
|
2016-10-07 |
2021-05-11 |
Biolog Life Science Institute Gmbh & Co. Kg |
Cyclic dinucleotides containing benzimidazole, method for the production of same, and use of same to activate stimulator of interferon genes (sting)-dependent signaling pathways
|
|
US11242593B2
(en)
|
2016-11-30 |
2022-02-08 |
Jfe Steel Corporation |
Steel for nitrocarburizing, and component
|
|
PE20210255A1
(es)
|
2016-12-01 |
2021-02-10 |
Takeda Pharmaceuticals Co |
Dinucleotido ciclico como agonistas de sting (estimulador de genes de interferon)
|
|
NZ762505A
(en)
*
|
2017-09-29 |
2026-03-27 |
Daiichi Sankyo Co Ltd |
Antibody-pyrrolobenzodiazepine derivative conjugate
|
|
TW202504930A
(zh)
*
|
2018-06-27 |
2025-02-01 |
台灣浩鼎生技股份有限公司 |
用於糖蛋白工程的糖苷合成酶變體及其使用方法
|
|
JP7510249B2
(ja)
|
2018-07-28 |
2024-07-03 |
公益財団法人野口研究所 |
複合型糖鎖を遊離する方法
|
|
EP3848054B1
(en)
*
|
2018-09-06 |
2025-01-29 |
Daiichi Sankyo Company, Limited |
Antibody-drug conjugates of cyclic dinucleotide derivatives
|
|
JP6732150B1
(ja)
|
2019-03-06 |
2020-07-29 |
東京インキ株式会社 |
熱ラミネート用スチレンフィルム用グラビア印刷インキ組成物
|