JPWO2021193954A1 - - Google Patents
Info
- Publication number
- JPWO2021193954A1 JPWO2021193954A1 JP2022510762A JP2022510762A JPWO2021193954A1 JP WO2021193954 A1 JPWO2021193954 A1 JP WO2021193954A1 JP 2022510762 A JP2022510762 A JP 2022510762A JP 2022510762 A JP2022510762 A JP 2022510762A JP WO2021193954 A1 JPWO2021193954 A1 JP WO2021193954A1
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/02—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/42—Separation; Purification; Stabilisation; Use of additives
- C07C51/43—Separation; Purification; Stabilisation; Use of additives by change of the physical state, e.g. crystallisation
- C07C51/44—Separation; Purification; Stabilisation; Use of additives by change of the physical state, e.g. crystallisation by distillation
- C07C51/46—Separation; Purification; Stabilisation; Use of additives by change of the physical state, e.g. crystallisation by distillation by azeotropic distillation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2020058880 | 2020-03-27 | ||
| JP2020058880 | 2020-03-27 | ||
| PCT/JP2021/013023 WO2021193954A1 (ja) | 2020-03-27 | 2021-03-26 | 核酸オリゴマーの製造方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPWO2021193954A1 true JPWO2021193954A1 (https=) | 2021-09-30 |
| JP7698631B2 JP7698631B2 (ja) | 2025-06-25 |
Family
ID=77892293
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022510762A Active JP7698631B2 (ja) | 2020-03-27 | 2021-03-26 | 核酸オリゴマーの製造方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US12522629B2 (https=) |
| EP (1) | EP4130018A4 (https=) |
| JP (1) | JP7698631B2 (https=) |
| KR (1) | KR20220160010A (https=) |
| CN (1) | CN115335387A (https=) |
| WO (1) | WO2021193954A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117980285A (zh) * | 2021-09-28 | 2024-05-03 | 住友化学株式会社 | 纯化二氯乙酸的制造方法 |
| CN116333007B (zh) * | 2021-12-23 | 2025-06-03 | 中国科学院化学研究所 | 一种基于点击化学的光响应性环形rna合成方法及其应用 |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012017919A1 (ja) * | 2010-08-03 | 2012-02-09 | 株式会社ボナック | 含窒素脂環式骨格を有する一本鎖核酸分子 |
| WO2013103146A1 (ja) * | 2012-01-07 | 2013-07-11 | 株式会社ボナック | アミノ酸骨格を有する一本鎖核酸分子 |
| WO2016158809A1 (ja) * | 2015-03-27 | 2016-10-06 | 株式会社ボナック | デリバリー機能と遺伝子発現制御能を有する一本鎖核酸分子 |
| WO2017131237A1 (ja) * | 2016-01-30 | 2017-08-03 | 株式会社ボナック | 人工単一ガイドｒｎａ及びその用途 |
| WO2019189722A1 (ja) * | 2018-03-30 | 2019-10-03 | 東レ株式会社 | ヘアピン型一本鎖ｒｎａ分子の製造方法 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7273933B1 (en) | 1998-02-26 | 2007-09-25 | Isis Pharmaceuticals, Inc. | Methods for synthesis of oligonucleotides |
| US6077709A (en) | 1998-09-29 | 2000-06-20 | Isis Pharmaceuticals Inc. | Antisense modulation of Survivin expression |
| US6887990B1 (en) | 1999-02-05 | 2005-05-03 | Amersham Biosciences Corp | Method for deprotecting oligonucleotides |
| US6261840B1 (en) | 2000-01-18 | 2001-07-17 | Isis Pharmaceuticals, Inc. | Antisense modulation of PTP1B expression |
| AU2005275801B2 (en) | 2004-08-26 | 2012-05-10 | Nippon Shinyaku Co., Ltd. | Phosphoramidite compound and method for producing oligo-RNA |
| ES2526295T5 (es) | 2006-10-18 | 2021-05-04 | Ionis Pharmaceuticals Inc | Compuestos antisentido |
| WO2011005595A2 (en) * | 2009-06-24 | 2011-01-13 | Alios Biopharma, Inc. | 2-5a analogs and their methods of use |
| EP2933333B1 (en) | 2010-07-08 | 2018-02-21 | Bonac Corporation | Single-strand nucleic acid molecule for controlling gene expression |
| MX351566B (es) * | 2011-06-21 | 2017-10-19 | Akzo Nobel Chemicals Int Bv | Proceso para separar acido monocloroacetico y acido dicloroacetico mediante destilacion extractiva. |
| MX370398B (es) * | 2011-08-25 | 2019-12-11 | Bonac Corp | Compuesto de glicosido, metodo para producir tioeter, eter, metodo para producir eter, metodo para producir un compuesto de glicosido, metodo para producir acido nucleico. |
| AU2013266968B2 (en) | 2012-05-25 | 2017-06-29 | Emmanuelle CHARPENTIER | Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription |
| HUE051986T2 (hu) * | 2014-06-24 | 2021-04-28 | Janssen Biopharma Inc | Helyettesített nukleozidok, nukleotidek és analógjaik virális fertõzés kezelésére való alkalmazásra |
| CA2969619A1 (en) | 2014-12-03 | 2016-06-09 | Agilent Technologies, Inc. | Guide rna with chemical modifications |
| EP3328337B1 (en) | 2015-07-31 | 2022-08-17 | The Procter & Gamble Company | Package of absorbent articles utilizing a shaped nonwoven |
| JPWO2018182008A1 (ja) | 2017-03-31 | 2020-02-06 | 株式会社ボナック | 遺伝子発現制御機能を有する環状型核酸分子 |
| BR112020005230A2 (pt) | 2017-09-19 | 2020-09-24 | Alnylam Pharmaceuticals, Inc. | composições e métodos para o tratamento da amiloidose mediada por transtiretina (ttr) |
| US20210188895A1 (en) | 2017-10-13 | 2021-06-24 | Bonac Corporation | Single-stranded nucleic acid molecule, and production method therefor |
| KR102670605B1 (ko) | 2018-04-24 | 2024-05-29 | 스미또모 가가꾸 가부시끼가이샤 | 아미다이트 화합물 및 그 화합물을 사용한 폴리뉴클레오티드의 제조 방법 |
| US20220325309A1 (en) | 2019-08-08 | 2022-10-13 | Sumitomo Chemical Company, Limited | Method for producing nucleic acid molecule |
-
2021
- 2021-03-26 EP EP21774023.2A patent/EP4130018A4/en active Pending
- 2021-03-26 JP JP2022510762A patent/JP7698631B2/ja active Active
- 2021-03-26 CN CN202180023282.5A patent/CN115335387A/zh active Pending
- 2021-03-26 US US17/906,820 patent/US12522629B2/en active Active
- 2021-03-26 WO PCT/JP2021/013023 patent/WO2021193954A1/ja not_active Ceased
- 2021-03-26 KR KR1020227035118A patent/KR20220160010A/ko active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012017919A1 (ja) * | 2010-08-03 | 2012-02-09 | 株式会社ボナック | 含窒素脂環式骨格を有する一本鎖核酸分子 |
| WO2013103146A1 (ja) * | 2012-01-07 | 2013-07-11 | 株式会社ボナック | アミノ酸骨格を有する一本鎖核酸分子 |
| WO2016158809A1 (ja) * | 2015-03-27 | 2016-10-06 | 株式会社ボナック | デリバリー機能と遺伝子発現制御能を有する一本鎖核酸分子 |
| WO2017131237A1 (ja) * | 2016-01-30 | 2017-08-03 | 株式会社ボナック | 人工単一ガイドｒｎａ及びその用途 |
| WO2019189722A1 (ja) * | 2018-03-30 | 2019-10-03 | 東レ株式会社 | ヘアピン型一本鎖ｒｎａ分子の製造方法 |
Non-Patent Citations (3)
| Title |
|---|
| BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY, vol. 13, JPN6021022004, 2017, pages 1368 - 1387, ISSN: 0005525454 * |
| NUCLEIC ACIDS RESEARCH, vol. 24, JPN6021022002, 1996, pages 3048 - 3052, ISSN: 0005525452 * |
| NUCLEIC ACIDS RESEARCH, vol. 24, JPN6021022003, 1996, pages 3053 - 3058, ISSN: 0005525453 * |
Also Published As
| Publication number | Publication date |
|---|---|
| US20230167152A1 (en) | 2023-06-01 |
| EP4130018A1 (en) | 2023-02-08 |
| KR20220160010A (ko) | 2022-12-05 |
| CN115335387A (zh) | 2022-11-11 |
| WO2021193954A1 (ja) | 2021-09-30 |
| EP4130018A4 (en) | 2024-04-17 |
| US12522629B2 (en) | 2026-01-13 |
| JP7698631B2 (ja) | 2025-06-25 |
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