JPWO2021193954A1 - - Google Patents

Info

Publication number
JPWO2021193954A1
JPWO2021193954A1 JP2022510762A JP2022510762A JPWO2021193954A1 JP WO2021193954 A1 JPWO2021193954 A1 JP WO2021193954A1 JP 2022510762 A JP2022510762 A JP 2022510762A JP 2022510762 A JP2022510762 A JP 2022510762A JP WO2021193954 A1 JPWO2021193954 A1 JP WO2021193954A1
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022510762A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of JPWO2021193954A1 publication Critical patent/JPWO2021193954A1/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/02—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C07C51/43—Separation; Purification; Stabilisation; Use of additives by change of the physical state, e.g. crystallisation
    • C07C51/44—Separation; Purification; Stabilisation; Use of additives by change of the physical state, e.g. crystallisation by distillation
    • C07C51/46—Separation; Purification; Stabilisation; Use of additives by change of the physical state, e.g. crystallisation by distillation by azeotropic distillation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Saccharide Compounds (AREA)
JP2022510762A 2020-03-27 2021-03-26 Pending JPWO2021193954A1 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2020058880 2020-03-27
PCT/JP2021/013023 WO2021193954A1 (ja) 2020-03-27 2021-03-26 核酸オリゴマーの製造方法

Publications (1)

Publication Number Publication Date
JPWO2021193954A1 true JPWO2021193954A1 (ja) 2021-09-30

Family

ID=77892293

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022510762A Pending JPWO2021193954A1 (ja) 2020-03-27 2021-03-26

Country Status (6)

Country Link
US (1) US20230167152A1 (ja)
EP (1) EP4130018A4 (ja)
JP (1) JPWO2021193954A1 (ja)
KR (1) KR20220160010A (ja)
CN (1) CN115335387A (ja)
WO (1) WO2021193954A1 (ja)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117980285A (zh) * 2021-09-28 2024-05-03 住友化学株式会社 纯化二氯乙酸的制造方法

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7273933B1 (en) * 1998-02-26 2007-09-25 Isis Pharmaceuticals, Inc. Methods for synthesis of oligonucleotides
US6077709A (en) 1998-09-29 2000-06-20 Isis Pharmaceuticals Inc. Antisense modulation of Survivin expression
EP1149109B1 (en) 1999-02-05 2009-09-16 Amersham Biosciences Corp. Method for deprotecting oligonucleotides
US6261840B1 (en) 2000-01-18 2001-07-17 Isis Pharmaceuticals, Inc. Antisense modulation of PTP1B expression
WO2006022323A1 (ja) 2004-08-26 2006-03-02 Nippon Shinyaku Co., Ltd. ホスホロアミダイト化合物及びオリゴｒｎａの製法
EP2092065B2 (en) 2006-10-18 2019-07-24 Ionis Pharmaceuticals, Inc. Antisense compounds
WO2011005595A2 (en) * 2009-06-24 2011-01-13 Alios Biopharma, Inc. 2-5a analogs and their methods of use
WO2012005368A1 (ja) 2010-07-08 2012-01-12 株式会社ボナック 遺伝子発現制御のための一本鎖核酸分子
US8691782B2 (en) 2010-08-03 2014-04-08 Bonac Corporation Single-stranded nucleic acid molecule having nitrogen-containing alicyclic skeleton
DK2674494T3 (en) * 2010-08-03 2015-02-23 Bonac Corp Single-stranded RNA molecule with a nitrogen-containing alicyclic skeleton
EP2749565B1 (en) 2011-08-25 2017-05-31 Bonac Corporation Nucleoside phosphoramidates for producing nucleic acids
ES2645996T3 (es) * 2012-01-07 2017-12-11 Bonac Corporation Molécula de ácido nucleico monocatenario que tiene una cadena principal de aminoácidos
DE202013012242U1 (de) 2012-05-25 2016-02-02 Emmanuelle Charpentier Zusammensetzungen für die durch RNA gesteuerte Modifikation einer Ziel-DNA und für die durch RNA gesteuerte Modulation der Transkription
EP3797782A1 (en) * 2014-06-24 2021-03-31 Janssen BioPharma, Inc. Substituted nucleosides, nucleotides and analogs thereof for use in the treatment of viral infections
JP7068821B2 (ja) 2014-12-03 2022-05-17 アジレント・テクノロジーズ・インク 化学修飾を有するガイドｒｎａ
ES2926369T3 (es) * 2015-03-27 2022-10-25 Bonac Corp Molécula de ácido nucleico monocatenario que tiene función de suministro y capacidad de control de la expresión génica
US11826230B2 (en) 2015-07-31 2023-11-28 The Procter & Gamble Company Package of absorbent articles utilizing a shaped nonwoven
CN109072224B (zh) * 2016-01-30 2022-07-15 株式会社博纳克 人工单导rna及其用途
US20200038427A1 (en) 2017-03-31 2020-02-06 Bonac Corporation Cyclic nucleic acid molecule having gene expression control function
KR20200089656A (ko) 2017-09-19 2020-07-27 알닐람 파마슈티칼스 인코포레이티드 트랜스타이레틴(ttr) 매개 아밀로이드증을 치료하기 위한 조성물 및 방법
WO2019074110A1 (ja) 2017-10-13 2019-04-18 株式会社ボナック 一本鎖核酸分子およびその製造方法
US11920131B2 (en) * 2018-03-30 2024-03-05 Toray Industries, Inc. Method of producing hairpin single-stranded RNA molecule
US11401296B2 (en) 2018-04-24 2022-08-02 Sumitomo Chemical Company, Limited Amidite compound and method for producing polynucleotide using said compound
JP6828219B1 (ja) * 2019-08-08 2021-02-10 住友化学株式会社 核酸分子の製造方法

Also Published As

Publication number Publication date
CN115335387A (zh) 2022-11-11
WO2021193954A1 (ja) 2021-09-30
US20230167152A1 (en) 2023-06-01
EP4130018A1 (en) 2023-02-08
EP4130018A4 (en) 2024-04-17
KR20220160010A (ko) 2022-12-05

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Legal Events

Date Code Title Description
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Effective date: 20231215