JPWO2021156489A5 - - Google Patents
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- Publication number
- JPWO2021156489A5 JPWO2021156489A5 JP2022547688A JP2022547688A JPWO2021156489A5 JP WO2021156489 A5 JPWO2021156489 A5 JP WO2021156489A5 JP 2022547688 A JP2022547688 A JP 2022547688A JP 2022547688 A JP2022547688 A JP 2022547688A JP WO2021156489 A5 JPWO2021156489 A5 JP WO2021156489A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- polypeptide
- amino acid
- fragment
- terminus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229920001184 polypeptide Polymers 0.000 claims 43
- 108090000765 processed proteins & peptides Proteins 0.000 claims 43
- 102000004196 processed proteins & peptides Human genes 0.000 claims 43
- 150000001413 amino acids Chemical class 0.000 claims 27
- 239000012634 fragment Substances 0.000 claims 23
- 229910052700 potassium Inorganic materials 0.000 claims 10
- 239000013598 vector Substances 0.000 claims 9
- 125000003275 alpha amino acid group Chemical group 0.000 claims 8
- 150000007523 nucleic acids Chemical class 0.000 claims 8
- 108700025771 adenovirus penton Proteins 0.000 claims 6
- 230000027455 binding Effects 0.000 claims 6
- 238000000034 method Methods 0.000 claims 6
- 229910052717 sulfur Inorganic materials 0.000 claims 6
- 210000004027 cell Anatomy 0.000 claims 5
- 238000012986 modification Methods 0.000 claims 5
- 230000004048 modification Effects 0.000 claims 5
- 239000008194 pharmaceutical composition Substances 0.000 claims 5
- 210000004671 cell-free system Anatomy 0.000 claims 4
- 229910052757 nitrogen Inorganic materials 0.000 claims 4
- 108020004707 nucleic acids Proteins 0.000 claims 4
- 102000039446 nucleic acids Human genes 0.000 claims 4
- 125000001433 C-terminal amino-acid group Chemical group 0.000 claims 3
- 125000001429 N-terminal alpha-amino-acid group Chemical group 0.000 claims 3
- 108010038807 Oligopeptides Proteins 0.000 claims 3
- 102000015636 Oligopeptides Human genes 0.000 claims 3
- 125000003636 chemical group Chemical group 0.000 claims 3
- 206010028980 Neoplasm Diseases 0.000 claims 2
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 2
- 101710173835 Penton protein Proteins 0.000 claims 2
- 108010003723 Single-Domain Antibodies Proteins 0.000 claims 2
- 239000000427 antigen Substances 0.000 claims 2
- 108091007433 antigens Proteins 0.000 claims 2
- 102000036639 antigens Human genes 0.000 claims 2
- 229910052739 hydrogen Inorganic materials 0.000 claims 2
- 230000009870 specific binding Effects 0.000 claims 2
- 239000000126 substance Substances 0.000 claims 2
- 108010032595 Antibody Binding Sites Proteins 0.000 claims 1
- 102000006306 Antigen Receptors Human genes 0.000 claims 1
- 108010083359 Antigen Receptors Proteins 0.000 claims 1
- 101710167800 Capsid assembly scaffolding protein Proteins 0.000 claims 1
- 208000035473 Communicable disease Diseases 0.000 claims 1
- 108060003951 Immunoglobulin Proteins 0.000 claims 1
- 108010021625 Immunoglobulin Fragments Proteins 0.000 claims 1
- 102000008394 Immunoglobulin Fragments Human genes 0.000 claims 1
- 101710130420 Probable capsid assembly scaffolding protein Proteins 0.000 claims 1
- 101710204410 Scaffold protein Proteins 0.000 claims 1
- 210000001744 T-lymphocyte Anatomy 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 229910052799 carbon Inorganic materials 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 230000037430 deletion Effects 0.000 claims 1
- 238000012217 deletion Methods 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 238000010494 dissociation reaction Methods 0.000 claims 1
- 230000005593 dissociations Effects 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 230000009977 dual effect Effects 0.000 claims 1
- 108020001507 fusion proteins Proteins 0.000 claims 1
- 102000037865 fusion proteins Human genes 0.000 claims 1
- 208000026278 immune system disease Diseases 0.000 claims 1
- 102000018358 immunoglobulin Human genes 0.000 claims 1
- 230000037431 insertion Effects 0.000 claims 1
- 238000003780 insertion Methods 0.000 claims 1
- 235000015110 jellies Nutrition 0.000 claims 1
- 239000008274 jelly Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 230000035772 mutation Effects 0.000 claims 1
- -1 not present) or N Chemical class 0.000 claims 1
- 239000002773 nucleotide Substances 0.000 claims 1
- 125000003729 nucleotide group Chemical group 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 229910052698 phosphorus Inorganic materials 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 238000000746 purification Methods 0.000 claims 1
- 238000006467 substitution reaction Methods 0.000 claims 1
- 239000003053 toxin Substances 0.000 claims 1
- 231100000765 toxin Toxicity 0.000 claims 1
- 108700012359 toxins Proteins 0.000 claims 1
- 231100000611 venom Toxicity 0.000 claims 1
- 239000002435 venom Substances 0.000 claims 1
- 210000001048 venom Anatomy 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP20155742 | 2020-02-05 | ||
| EP20155742.8 | 2020-02-05 | ||
| EP20155982 | 2020-02-06 | ||
| EP20155982.0 | 2020-02-06 | ||
| PCT/EP2021/052884 WO2021156489A1 (en) | 2020-02-05 | 2021-02-05 | Engineered polypeptides derived from variable domain of adenovirus penton base |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023513512A JP2023513512A (ja) | 2023-03-31 |
| JP2023513512A5 JP2023513512A5 (https=) | 2024-02-14 |
| JPWO2021156489A5 true JPWO2021156489A5 (https=) | 2024-02-14 |
Family
ID=74561908
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022547688A Pending JP2023513512A (ja) | 2020-02-05 | 2021-02-05 | アデノウイルス ペントンベースの可変ドメイン由来の操作されたポリペプチド |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20230101439A1 (https=) |
| EP (1) | EP4100421A1 (https=) |
| JP (1) | JP2023513512A (https=) |
| CN (1) | CN115427431A (https=) |
| AU (1) | AU2021216124A1 (https=) |
| BR (1) | BR112022015461A2 (https=) |
| CA (1) | CA3166852A1 (https=) |
| MX (1) | MX2022009574A (https=) |
| WO (1) | WO2021156489A1 (https=) |
| ZA (1) | ZA202209759B (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024042100A1 (en) | 2022-08-22 | 2024-02-29 | Imophoron Limited | Adenovirus penton-based virus-like particles |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4597188B2 (ja) | 2004-03-09 | 2010-12-15 | アイトゲネシシェ・テヒニーシェ・ホッホシューレ・チューリッヒ | 多タンパク質適用のための新規発現ツール |
| JP2012519476A (ja) | 2009-03-06 | 2012-08-30 | ヨーロピアン モレキュラー バイオロジー ラボラトリー | 多タンパク質複合体のクローニング及び発現のための核酸 |
| PL222497B1 (pl) * | 2009-06-26 | 2016-08-31 | Inst Biochemii I Biofizyki Pan | Wektorowa cząsteczka wirusopodobna, sposób jej wytwarzania, kompozycja farmaceutyczna oraz zastosowanie wektorowej cząsteczki wirusopodobnej |
| EP3436591B1 (en) | 2016-03-31 | 2023-01-04 | The European Molecular Biology Laboratory | Adenoviral coat protein derived delivery vehicles |
| WO2019016756A1 (en) * | 2017-07-21 | 2019-01-24 | Glaxosmithkline Biologicals Sa | ANTIGEN CONSTRUCTS OF CHIKUNGUNYA VIRUSES |
| SG11202100898UA (en) * | 2018-07-31 | 2021-02-25 | Imophoron Ltd | Multimerizing polypeptides derived from jelly roll fold domain of adenovirus penton base |
-
2021
- 2021-02-05 MX MX2022009574A patent/MX2022009574A/es unknown
- 2021-02-05 BR BR112022015461A patent/BR112022015461A2/pt not_active IP Right Cessation
- 2021-02-05 WO PCT/EP2021/052884 patent/WO2021156489A1/en not_active Ceased
- 2021-02-05 CA CA3166852A patent/CA3166852A1/en active Pending
- 2021-02-05 AU AU2021216124A patent/AU2021216124A1/en not_active Abandoned
- 2021-02-05 JP JP2022547688A patent/JP2023513512A/ja active Pending
- 2021-02-05 CN CN202180024156.1A patent/CN115427431A/zh active Pending
- 2021-02-05 US US17/797,941 patent/US20230101439A1/en active Pending
- 2021-02-05 EP EP21703917.1A patent/EP4100421A1/en not_active Withdrawn
-
2022
- 2022-08-31 ZA ZA2022/09759A patent/ZA202209759B/en unknown
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