JPWO2022125566A5 - - Google Patents

Info

Publication number

JPWO2022125566A5

JPWO2022125566A5 JP2023534636A JP2023534636A JPWO2022125566A5 JP WO2022125566 A5 JPWO2022125566 A5 JP WO2022125566A5 JP 2023534636 A JP2023534636 A JP 2023534636A JP 2023534636 A JP2023534636 A JP 2023534636A JP WO2022125566 A5 JPWO2022125566 A5 JP WO2022125566A5

Authority

JP

Japan

Prior art keywords

seq

amino acid

polypeptide

cdr1

cdr2

Prior art date

2024-12-12

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

Links

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• 108090000765 processed proteins & peptides Proteins 0.000 claims 35
• 229920001184 polypeptide Polymers 0.000 claims 34
• 102000004196 processed proteins & peptides Human genes 0.000 claims 34
• 125000003275 alpha amino acid group Chemical group 0.000 claims 10
• 108010047041 Complementarity Determining Regions Proteins 0.000 claims 8
• 125000000539 amino acid group Chemical group 0.000 claims 6
• 108010021625 Immunoglobulin Fragments Proteins 0.000 claims 4
• 102000008394 Immunoglobulin Fragments Human genes 0.000 claims 4
• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 3
• 239000000427 antigen Substances 0.000 claims 3
• 102000036639 antigens Human genes 0.000 claims 3
• 108091007433 antigens Proteins 0.000 claims 3
• 102000039446 nucleic acids Human genes 0.000 claims 3
• 108020004707 nucleic acids Proteins 0.000 claims 3
• 150000007523 nucleic acids Chemical class 0.000 claims 3
• 108010003723 Single-Domain Antibodies Proteins 0.000 claims 2
• 238000012986 modification Methods 0.000 claims 2
• 230000004048 modification Effects 0.000 claims 2
• 206010028980 Neoplasm Diseases 0.000 claims 1
• 108091005804 Peptidases Proteins 0.000 claims 1
• 239000004365 Protease Substances 0.000 claims 1
• 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 claims 1
• 239000012634 fragment Substances 0.000 claims 1
• 239000008194 pharmaceutical composition Substances 0.000 claims 1
• 239000000546 pharmaceutical excipient Substances 0.000 claims 1
• 239000000758 substrate Substances 0.000 claims 1