JP2025124718A5 - - Google Patents

Info

Publication number
JP2025124718A5
JP2025124718A5 JP2025084749A JP2025084749A JP2025124718A5 JP 2025124718 A5 JP2025124718 A5 JP 2025124718A5 JP 2025084749 A JP2025084749 A JP 2025084749A JP 2025084749 A JP2025084749 A JP 2025084749A JP 2025124718 A5 JP2025124718 A5 JP 2025124718A5
Authority
JP
Japan
Prior art keywords
kalbtg
recognition site
seq
modified antibody
antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2025084749A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025124718A (ja
Filing date
Publication date
Priority claimed from EP21217585.5A external-priority patent/EP4201956A1/en
Application filed filed Critical
Publication of JP2025124718A publication Critical patent/JP2025124718A/ja
Publication of JP2025124718A5 publication Critical patent/JP2025124718A5/ja
Pending legal-status Critical Current

Links

JP2025084749A 2021-12-23 2025-05-21 部位特異的抗体コンジュゲーション及びその使用 Pending JP2025124718A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP21217585.5 2021-12-23
EP21217585.5A EP4201956A1 (en) 2021-12-23 2021-12-23 Kutzneria albida (kalbtg) transglutaminase used for antibody conjugations
JP2022206731A JP7686613B2 (ja) 2021-12-23 2022-12-23 部位特異的抗体コンジュゲーション及びその使用

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2022206731A Division JP7686613B2 (ja) 2021-12-23 2022-12-23 部位特異的抗体コンジュゲーション及びその使用

Publications (2)

Publication Number Publication Date
JP2025124718A JP2025124718A (ja) 2025-08-26
JP2025124718A5 true JP2025124718A5 (https=) 2026-01-29

Family

ID=80119611

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2022206731A Active JP7686613B2 (ja) 2021-12-23 2022-12-23 部位特異的抗体コンジュゲーション及びその使用
JP2025084749A Pending JP2025124718A (ja) 2021-12-23 2025-05-21 部位特異的抗体コンジュゲーション及びその使用

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2022206731A Active JP7686613B2 (ja) 2021-12-23 2022-12-23 部位特異的抗体コンジュゲーション及びその使用

Country Status (14)

Country Link
US (1) US20230310641A1 (https=)
EP (2) EP4201956A1 (https=)
JP (2) JP7686613B2 (https=)
KR (1) KR20240118825A (https=)
CN (1) CN118434763A (https=)
AU (1) AU2022418204A1 (https=)
CA (1) CA3242447A1 (https=)
CL (1) CL2024001920A1 (https=)
CO (1) CO2024008389A2 (https=)
CR (1) CR20240256A (https=)
IL (1) IL313340A (https=)
MX (1) MX2024007648A (https=)
PE (1) PE20251186A1 (https=)
WO (1) WO2023118398A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025032071A1 (en) 2023-08-09 2025-02-13 F. Hoffmann-La Roche Ag Mono and multispecific anti-trem2 antibodies, methods and uses thereof
AU2024323186A1 (en) 2023-08-09 2026-01-15 F. Hoffmann-La Roche Ag Mono and multispecific anti-trem2 antibodies, methods and uses thereof
WO2025157804A1 (en) 2024-01-24 2025-07-31 F. Hoffmann-La Roche Ag Linkers for site-specific protein conjugation
WO2025215060A1 (en) 2024-04-11 2025-10-16 F. Hoffmann-La Roche Ag Antibodies that specifically bind modified oligonucleotides
WO2026037757A1 (en) * 2024-08-13 2026-02-19 F. Hoffmann-La Roche Ag Modified aav particles

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9676871B2 (en) * 2010-11-05 2017-06-13 Pfizer Inc. Engineered polypeptide conjugates and methods for making thereof using transglutaminase
US11054425B2 (en) * 2014-12-19 2021-07-06 Roche Sequencing Solutions, Inc. System and method for identification and characterization of transglutaminase species
ES2871624T3 (es) 2014-12-19 2021-10-29 Hoffmann La Roche Transglutaminasas microbianas, sustratos para las mismas y procedimientos para el uso de las mismas
KR102943992B1 (ko) 2015-12-15 2026-03-25 에프. 호프만-라 로슈 아게 트랜스글루타미나제 인식 부위를 갖는 fkbp 도메인
KR20210102334A (ko) * 2018-12-12 2021-08-19 브리스톨-마이어스 스큅 컴퍼니 트랜스글루타미나제 접합을 위해 변형된 항체, 그의 접합체, 및 방법 및 용도
BR112022017136A2 (pt) 2020-02-28 2022-10-11 Tallac Therapeutics Inc Conjugação mediada por transglutaminase

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