ZA202209759B - Engineered polypeptides derived from variable domain of adenovirus penton base - Google Patents

Engineered polypeptides derived from variable domain of adenovirus penton base

Info

Publication number
ZA202209759B
ZA202209759B ZA2022/09759A ZA202209759A ZA202209759B ZA 202209759 B ZA202209759 B ZA 202209759B ZA 2022/09759 A ZA2022/09759 A ZA 2022/09759A ZA 202209759 A ZA202209759 A ZA 202209759A ZA 202209759 B ZA202209759 B ZA 202209759B
Authority
ZA
South Africa
Prior art keywords
variable domain
polypeptides derived
engineered polypeptides
penton base
adenovirus penton
Prior art date
Application number
ZA2022/09759A
Other languages
English (en)
Inventor
Frédéric Garzoni
Original Assignee
Imophoron Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imophoron Ltd filed Critical Imophoron Ltd
Publication of ZA202209759B publication Critical patent/ZA202209759B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1055Protein x Protein interaction, e.g. two hybrid selection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/20Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/21Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/10011Adenoviridae
    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10322New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/10011Adenoviridae
    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10323Virus like particles [VLP]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/10011Adenoviridae
    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10333Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Microbiology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA2022/09759A 2020-02-05 2022-08-31 Engineered polypeptides derived from variable domain of adenovirus penton base ZA202209759B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP20155742 2020-02-05
EP20155982 2020-02-06
PCT/EP2021/052884 WO2021156489A1 (en) 2020-02-05 2021-02-05 Engineered polypeptides derived from variable domain of adenovirus penton base

Publications (1)

Publication Number Publication Date
ZA202209759B true ZA202209759B (en) 2023-07-26

Family

ID=74561908

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2022/09759A ZA202209759B (en) 2020-02-05 2022-08-31 Engineered polypeptides derived from variable domain of adenovirus penton base

Country Status (10)

Country Link
US (1) US20230101439A1 (https=)
EP (1) EP4100421A1 (https=)
JP (1) JP2023513512A (https=)
CN (1) CN115427431A (https=)
AU (1) AU2021216124A1 (https=)
BR (1) BR112022015461A2 (https=)
CA (1) CA3166852A1 (https=)
MX (1) MX2022009574A (https=)
WO (1) WO2021156489A1 (https=)
ZA (1) ZA202209759B (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024042100A1 (en) 2022-08-22 2024-02-29 Imophoron Limited Adenovirus penton-based virus-like particles

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4597188B2 (ja) 2004-03-09 2010-12-15 アイトゲネシシェ・テヒニーシェ・ホッホシューレ・チューリッヒ 多タンパク質適用のための新規発現ツール
JP2012519476A (ja) 2009-03-06 2012-08-30 ヨーロピアン モレキュラー バイオロジー ラボラトリー 多タンパク質複合体のクローニング及び発現のための核酸
PL222497B1 (pl) * 2009-06-26 2016-08-31 Inst Biochemii I Biofizyki Pan Wektorowa cząsteczka wirusopodobna, sposób jej wytwarzania, kompozycja farmaceutyczna oraz zastosowanie wektorowej cząsteczki wirusopodobnej
EP3436591B1 (en) 2016-03-31 2023-01-04 The European Molecular Biology Laboratory Adenoviral coat protein derived delivery vehicles
WO2019016756A1 (en) * 2017-07-21 2019-01-24 Glaxosmithkline Biologicals Sa ANTIGEN CONSTRUCTS OF CHIKUNGUNYA VIRUSES
SG11202100898UA (en) * 2018-07-31 2021-02-25 Imophoron Ltd Multimerizing polypeptides derived from jelly roll fold domain of adenovirus penton base

Also Published As

Publication number Publication date
US20230101439A1 (en) 2023-03-30
WO2021156489A1 (en) 2021-08-12
CN115427431A (zh) 2022-12-02
BR112022015461A2 (pt) 2022-10-11
EP4100421A1 (en) 2022-12-14
AU2021216124A1 (en) 2022-09-29
MX2022009574A (es) 2022-11-16
CA3166852A1 (en) 2021-08-12
JP2023513512A (ja) 2023-03-31

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