JP2023513512A - アデノウイルス ペントンベースの可変ドメイン由来の操作されたポリペプチド - Google Patents

アデノウイルス ペントンベースの可変ドメイン由来の操作されたポリペプチド Download PDF

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JP2023513512A
JP2023513512A JP2022547688A JP2022547688A JP2023513512A JP 2023513512 A JP2023513512 A JP 2023513512A JP 2022547688 A JP2022547688 A JP 2022547688A JP 2022547688 A JP2022547688 A JP 2022547688A JP 2023513512 A JP2023513512 A JP 2023513512A
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amino acid
polypeptide
fragment
present
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Japanese (ja)
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JP2023513512A5 (https=
JPWO2021156489A5 (https=
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ガルツォーニ、フレデリック
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イモフォロン リミテッド
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1055—Protein x Protein interaction, e.g. two hybrid selection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10323—Virus like particles [VLP]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10333—Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Microbiology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2022547688A 2020-02-05 2021-02-05 アデノウイルス ペントンベースの可変ドメイン由来の操作されたポリペプチド Pending JP2023513512A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP20155742 2020-02-05
EP20155742.8 2020-02-05
EP20155982 2020-02-06
EP20155982.0 2020-02-06
PCT/EP2021/052884 WO2021156489A1 (en) 2020-02-05 2021-02-05 Engineered polypeptides derived from variable domain of adenovirus penton base

Publications (3)

Publication Number Publication Date
JP2023513512A true JP2023513512A (ja) 2023-03-31
JP2023513512A5 JP2023513512A5 (https=) 2024-02-14
JPWO2021156489A5 JPWO2021156489A5 (https=) 2024-02-14

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ID=74561908

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JP2022547688A Pending JP2023513512A (ja) 2020-02-05 2021-02-05 アデノウイルス ペントンベースの可変ドメイン由来の操作されたポリペプチド

Country Status (10)

Country Link
US (1) US20230101439A1 (https=)
EP (1) EP4100421A1 (https=)
JP (1) JP2023513512A (https=)
CN (1) CN115427431A (https=)
AU (1) AU2021216124A1 (https=)
BR (1) BR112022015461A2 (https=)
CA (1) CA3166852A1 (https=)
MX (1) MX2022009574A (https=)
WO (1) WO2021156489A1 (https=)
ZA (1) ZA202209759B (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024042100A1 (en) 2022-08-22 2024-02-29 Imophoron Limited Adenovirus penton-based virus-like particles

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017167988A1 (en) * 2016-03-31 2017-10-05 The European Molecular Biology Laboratory Adenoviral coat protein derived delivery vehicles
WO2020025724A1 (en) * 2018-07-31 2020-02-06 Imophoron Ltd. Multimerizing polypeptides derived from jelly roll fold domain of adenovirus penton base

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4597188B2 (ja) 2004-03-09 2010-12-15 アイトゲネシシェ・テヒニーシェ・ホッホシューレ・チューリッヒ 多タンパク質適用のための新規発現ツール
JP2012519476A (ja) 2009-03-06 2012-08-30 ヨーロピアン モレキュラー バイオロジー ラボラトリー 多タンパク質複合体のクローニング及び発現のための核酸
PL222497B1 (pl) * 2009-06-26 2016-08-31 Inst Biochemii I Biofizyki Pan Wektorowa cząsteczka wirusopodobna, sposób jej wytwarzania, kompozycja farmaceutyczna oraz zastosowanie wektorowej cząsteczki wirusopodobnej
WO2019016756A1 (en) * 2017-07-21 2019-01-24 Glaxosmithkline Biologicals Sa ANTIGEN CONSTRUCTS OF CHIKUNGUNYA VIRUSES

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017167988A1 (en) * 2016-03-31 2017-10-05 The European Molecular Biology Laboratory Adenoviral coat protein derived delivery vehicles
WO2020025724A1 (en) * 2018-07-31 2020-02-06 Imophoron Ltd. Multimerizing polypeptides derived from jelly roll fold domain of adenovirus penton base

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
SZURGOT, I ET AL.: "Self-adjuvanting influenza candidate vaccine presenting epitopes for cell-mediated immunity on a pro", VACCINE, vol. 31, JPN6023035080, 2013, pages 4338 - 4346, ISSN: 0005572153 *

Also Published As

Publication number Publication date
US20230101439A1 (en) 2023-03-30
WO2021156489A1 (en) 2021-08-12
CN115427431A (zh) 2022-12-02
BR112022015461A2 (pt) 2022-10-11
ZA202209759B (en) 2023-07-26
EP4100421A1 (en) 2022-12-14
AU2021216124A1 (en) 2022-09-29
MX2022009574A (es) 2022-11-16
CA3166852A1 (en) 2021-08-12

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