JP2024073531A5 - - Google Patents

Download PDF

Info

Publication number
JP2024073531A5
JP2024073531A5 JP2024038103A JP2024038103A JP2024073531A5 JP 2024073531 A5 JP2024073531 A5 JP 2024073531A5 JP 2024038103 A JP2024038103 A JP 2024038103A JP 2024038103 A JP2024038103 A JP 2024038103A JP 2024073531 A5 JP2024073531 A5 JP 2024073531A5
Authority
JP
Japan
Prior art keywords
nucleic acid
polypeptide
variable domain
pichia host
immunoglobulin single
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2024038103A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024073531A (ja
JP7849405B2 (ja
Filing date
Publication date
Priority claimed from PCT/EP2017/053034 external-priority patent/WO2017137579A1/en
Application filed filed Critical
Publication of JP2024073531A publication Critical patent/JP2024073531A/ja
Publication of JP2024073531A5 publication Critical patent/JP2024073531A5/ja
Application granted granted Critical
Publication of JP7849405B2 publication Critical patent/JP7849405B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2024038103A 2016-02-12 2024-03-12 免疫グロブリン単一可変ドメインの生成方法 Active JP7849405B2 (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201662294470P 2016-02-12 2016-02-12
US62/294,470 2016-02-12
PCT/EP2017/053034 WO2017137579A1 (en) 2016-02-12 2017-02-10 Method for the production of immunoglobulin single variable domains
JP2018542263A JP7540877B2 (ja) 2016-02-12 2017-02-10 免疫グロブリン単一可変ドメインの生成方法

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2018542263A Division JP7540877B2 (ja) 2016-02-12 2017-02-10 免疫グロブリン単一可変ドメインの生成方法

Publications (3)

Publication Number Publication Date
JP2024073531A JP2024073531A (ja) 2024-05-29
JP2024073531A5 true JP2024073531A5 (https=) 2024-11-11
JP7849405B2 JP7849405B2 (ja) 2026-04-21

Family

ID=58018106

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2018542263A Active JP7540877B2 (ja) 2016-02-12 2017-02-10 免疫グロブリン単一可変ドメインの生成方法
JP2024038103A Active JP7849405B2 (ja) 2016-02-12 2024-03-12 免疫グロブリン単一可変ドメインの生成方法

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2018542263A Active JP7540877B2 (ja) 2016-02-12 2017-02-10 免疫グロブリン単一可変ドメインの生成方法

Country Status (7)

Country Link
US (2) US10975141B2 (https=)
EP (1) EP3414268A1 (https=)
JP (2) JP7540877B2 (https=)
CN (1) CN108699151B (https=)
AU (2) AU2017216864B2 (https=)
CA (1) CA3014443A1 (https=)
WO (1) WO2017137579A1 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO2768984T3 (https=) * 2015-11-12 2018-06-09
JP7540877B2 (ja) 2016-02-12 2024-08-27 アブリンクス エン.ヴェー. 免疫グロブリン単一可変ドメインの生成方法
EP3778865A4 (en) 2018-03-26 2021-12-22 National University Corporation Kobe University NEW CELL AND PROCESS FOR THE PRODUCTION OF A PROTEIN OF INTEREST USING IT
IL293561A (en) 2019-12-06 2022-08-01 Ablynx Nv Polypeptides comprising immunoglobulin with one variable domain targeting TNFa and IL-23
CN110964113B (zh) * 2019-12-24 2021-09-03 北京纽安博生物技术有限公司 介导结合免疫球蛋白的单域抗体、由其构建的双功能抗体及其应用
JP7714233B2 (ja) * 2020-03-19 2025-07-29 国立大学法人神戸大学 内在性遺伝子の発現が増強された遺伝子組換え細胞の製造方法
CN115397868A (zh) * 2020-03-30 2022-11-25 埃博灵克斯股份有限公司 用于产生和纯化多价免疫球蛋白单可变域的方法
FR3120865B1 (fr) 2021-03-19 2025-02-28 Univ Toulouse 3 Paul Sabatier Molécule hybride comprenant un fragment Fc d’anticorps et au moins un peptide citrulliné dérivé de la fibrine, et ses utilisations
FR3120877B1 (fr) 2021-03-19 2025-03-14 Univ Toulouse 3 Paul Sabatier Cellule immunitaire comprenant un récepteur Fc à sa surface, et sur lequel est greffé une molécule hybride comprenant un fragment Fc d’anticorps et au moins un peptide citrulliné dérivé de la fibrine, et ses utilisations
FR3120866B1 (fr) 2021-03-19 2025-02-28 Univ Toulouse 3 Paul Sabatier Molécule hybride comprenant un peptide citrulliné dérivé de la fibrine et un anticorps ou fragment d’anticorps se liant à CD38 et/ou CD138, et ses utilisations
CN114920839B (zh) * 2022-06-17 2023-03-10 天津大学 特异性结合il-23的纳米抗体及其用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2007250735A1 (en) * 2006-05-16 2007-11-22 Daiichi Sankyo Company, Limited Method for high-level secretory production of protein
EP2285833B1 (en) 2008-05-16 2014-12-17 Ablynx N.V. AMINO ACID SEQUENCES DIRECTED AGAINST CXCR4 AND OTHER GPCRs AND COMPOUNDS COMPRISING THE SAME
AU2010243551B2 (en) 2009-04-30 2015-03-26 Ablynx Nv Method for the production of domain antibodies
US8440456B2 (en) * 2009-05-22 2013-05-14 Vib, Vzw Nucleic acids of Pichia pastoris and use thereof for recombinant production of proteins
WO2011161266A1 (en) 2010-06-25 2011-12-29 Ablynx Nv Improved immunoglobulin single variable domains and constructs thereof directed against cxcr4
CN103917560B (zh) * 2011-03-28 2017-05-24 埃博灵克斯股份有限公司 双特异性抗‑cxcr7免疫球蛋白单可变结构域
EP4707303A2 (en) 2014-05-16 2026-03-11 Ablynx NV Improved immunoglobulin variable domains
JP7540877B2 (ja) 2016-02-12 2024-08-27 アブリンクス エン.ヴェー. 免疫グロブリン単一可変ドメインの生成方法

Similar Documents

Publication Publication Date Title
JP2024073531A5 (https=)
CN104302665B (zh) 与新生儿Fc受体的结合增强的变体Fc多肽
TWI359028B (en) Bivalent, bispecific antibodies
JP2019531704A5 (https=)
CN114450406B (zh) 一种断裂型内含肽、使用其的重组多肽的制备方法
JP5738294B2 (ja) 抗vegfモノクローナル抗体およびその抗体を含む薬学的組成物
JP2009523459A5 (https=)
JP2012515556A5 (https=)
JP2020500510A5 (https=)
TW200932269A (en) Bivalent, bispecific antibodies
JP2025063183A5 (https=)
JP2022009816A5 (https=)
JP2023509390A5 (https=)
US12000839B2 (en) Methods for characterizing disulfide bonds
JP2024509910A5 (https=)
CN116964084A (zh) 双特异性抗体
TW202423965A (zh) 與新生兒fc受體的特定表位結合之多肽
WO2026012501A1 (zh) 一种抗ngf单克隆抗体及其应用
CN117683134B (zh) 一种抗sla i纳米抗体及应用
CN117343182A (zh) 抗人tigit抗体或其功能性片段及其应用
US20220380440A1 (en) Truncated multivalent multimers
JP2024521987A5 (https=)
Mala et al. Construction and sequencing analysis of scFv antibody fragment derived from monoclonal antibody against norfloxacin (Nor155)
CN121712805A (zh) Ch3结构域变体或包含该ch3结构域变体的双特异性抗体
EP4382166A1 (en) Anti-pd-l1 nanobody and use thereof