JPWO2021095874A1 - - Google Patents

Info

Publication number
JPWO2021095874A1
JPWO2021095874A1 JP2021556191A JP2021556191A JPWO2021095874A1 JP WO2021095874 A1 JPWO2021095874 A1 JP WO2021095874A1 JP 2021556191 A JP2021556191 A JP 2021556191A JP 2021556191 A JP2021556191 A JP 2021556191A JP WO2021095874 A1 JPWO2021095874 A1 JP WO2021095874A1
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021556191A
Other versions
JPWO2021095874A5 (ja
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of JPWO2021095874A1 publication Critical patent/JPWO2021095874A1/ja
Publication of JPWO2021095874A5 publication Critical patent/JPWO2021095874A5/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Saccharide Compounds (AREA)
JP2021556191A 2019-11-13 2020-11-13 Pending JPWO2021095874A1 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2019205625 2019-11-13
PCT/JP2020/042505 WO2021095874A1 (ja) 2019-11-13 2020-11-13 オリゴ核酸化合物の製造方法

Publications (2)

Publication Number Publication Date
JPWO2021095874A1 true JPWO2021095874A1 (ja) 2021-05-20
JPWO2021095874A5 JPWO2021095874A5 (ja) 2023-11-16

Family

ID=75913043

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021556191A Pending JPWO2021095874A1 (ja) 2019-11-13 2020-11-13

Country Status (7)

Country Link
US (1) US20230018780A1 (ja)
EP (1) EP4059944A4 (ja)
JP (1) JPWO2021095874A1 (ja)
KR (1) KR20220098217A (ja)
CN (1) CN114981281A (ja)
CA (1) CA3161586A1 (ja)
WO (1) WO2021095874A1 (ja)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022230954A1 (ja) * 2021-04-28 2022-11-03 日本新薬株式会社 オリゴ核酸化合物の製造方法
WO2023127918A1 (ja) * 2021-12-27 2023-07-06 日本新薬株式会社 オリゴ核酸化合物の製造方法

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2130844A5 (ja) 1971-03-23 1972-11-10 Commissariat Energie Atomique
JPS5668388A (en) 1979-11-10 1981-06-09 Norin Suisansyo Shokuhin Sogo Kenkyusho Production of cell body of spirulina algae
JP3398378B2 (ja) 1989-12-20 2003-04-21 アンチビラルス・インコーポレイテツド リン含有キラルインターサブユニットリンケージを有する非電荷モルホリノ―基体ポリマー
US6313301B1 (en) 1997-08-13 2001-11-06 Takeda Chemical Industries, Ltd. Thienopyridine derivatives, their intermediates and production thereof
JPH1180185A (ja) * 1997-09-05 1999-03-26 Res Dev Corp Of Japan オリゴヌクレオチドの化学合成法
US6274725B1 (en) * 1998-06-02 2001-08-14 Isis Pharmaceuticals, Inc. Activators for oligonucleotide synthesis
DE60202681T2 (de) * 2001-07-12 2006-01-12 Santaris Pharma A/S Verfahren zur herstellung des lna phosphoramidite
CA2487036C (en) 2002-06-13 2008-10-28 Rhodia, Inc. Process of making phosphordiamidite compounds
US8067571B2 (en) * 2005-07-13 2011-11-29 Avi Biopharma, Inc. Antibacterial antisense oligonucleotide and method
JP2010527945A (ja) * 2007-05-22 2010-08-19 ギリンデュス アクチェンゲゼルシャフト オリゴヌクレオチドの合成
KR100886139B1 (ko) 2007-11-13 2009-02-27 주식회사 삼천리제약 올리고뉴클레오타이드의 제조방법
MX2010004955A (es) 2007-11-15 2010-06-30 Avi Biopharma Inc Metodo de sintesis de oligomeros de morfolina.
JP5548852B2 (ja) 2009-05-29 2014-07-16 国立大学法人東京農工大学 疎水性基結合ヌクレオシド、疎水性基結合ヌクレオシド溶液、及び疎水性基結合オリゴヌクレオチド合成方法
JP5831455B2 (ja) 2010-09-30 2015-12-09 日本新薬株式会社 モルホリノ核酸誘導体
EP2711370B1 (en) 2011-05-17 2018-01-03 Ajinomoto Co., Inc. Method for producing oligonucleotides
US9278987B2 (en) 2011-11-18 2016-03-08 Sarepta Therapeutics, Inc. Functionally-modified oligonucleotides and subunits thereof
US10066228B2 (en) 2011-11-30 2018-09-04 Sarepta Therapeutics, Inc. Oligonucleotides for treating expanded repeat diseases
JP6237237B2 (ja) 2012-02-17 2017-11-29 味の素株式会社 塩基部保護オリゴヌクレオチド
CN104918949B (zh) 2012-11-14 2017-10-10 武田药品工业株式会社 核酸的液相合成方法
EP3015467A4 (en) * 2013-05-24 2016-11-02 Ajinomoto Kk PROCESS FOR THE PRODUCTION OF MORPHOLINO-OLIGONUCLEOTIDE
EP3208277A4 (en) * 2014-10-14 2018-06-13 Ajinomoto Co., Inc. Morpholino oligonucleotide manufacturing method
DK3266792T3 (da) 2015-03-04 2021-02-01 Jitsubo Co Ltd Fremgangsmåde til peptidsyntese
CA3099778A1 (en) * 2018-05-10 2019-11-14 Nippon Shinyaku Co., Ltd. Method for preparing oligonucleic acid compound

Also Published As

Publication number Publication date
EP4059944A4 (en) 2024-04-10
CN114981281A (zh) 2022-08-30
CA3161586A1 (en) 2021-05-20
EP4059944A1 (en) 2022-09-21
US20230018780A1 (en) 2023-01-19
WO2021095874A1 (ja) 2021-05-20
KR20220098217A (ko) 2022-07-11

Similar Documents

Publication Publication Date Title
BR112019017762A2 (ja)
BR112021017339A2 (ja)
BR112021013854A2 (ja)
BR112021018450A2 (ja)
BR112019016141A2 (ja)
BR112019016142A2 (ja)
BR112019016138A2 (ja)
AU2020104490A5 (ja)
BR112021008711A2 (ja)
BR112021018452A2 (ja)
BR112021017234A2 (ja)
BR112021017355A2 (ja)
BR112021017703A2 (ja)
BR112021017173A2 (ja)
BR112021018584A2 (ja)
BR112021017083A2 (ja)
BR112021017637A2 (ja)
BR112021015080A2 (ja)
BR112021012348A2 (ja)
BR112021018250A2 (ja)
BR112021013944A2 (ja)
BR112021013128A2 (ja)
BR112021018484A2 (ja)
BR112021017983A2 (ja)
BR112021016205A2 (ja)

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20231108

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20231108