JPWO2021072372A5 - - Google Patents
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- Publication number
- JPWO2021072372A5 JPWO2021072372A5 JP2022521217A JP2022521217A JPWO2021072372A5 JP WO2021072372 A5 JPWO2021072372 A5 JP WO2021072372A5 JP 2022521217 A JP2022521217 A JP 2022521217A JP 2022521217 A JP2022521217 A JP 2022521217A JP WO2021072372 A5 JPWO2021072372 A5 JP WO2021072372A5
- Authority
- JP
- Japan
- Prior art keywords
- disease
- nucleic acid
- acid construct
- type
- alpha
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025167212A JP2026021331A (ja) | 2019-10-10 | 2025-10-03 | バリアントｉｇｆ２構築体 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962913677P | 2019-10-10 | 2019-10-10 | |
| US62/913,677 | 2019-10-10 | ||
| US201962929054P | 2019-10-31 | 2019-10-31 | |
| US62/929,054 | 2019-10-31 | ||
| PCT/US2020/055251 WO2021072372A1 (en) | 2019-10-10 | 2020-10-12 | Variant igf2 constructs |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025167212A Division JP2026021331A (ja) | 2019-10-10 | 2025-10-03 | バリアントｉｇｆ２構築体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022552254A JP2022552254A (ja) | 2022-12-15 |
| JP2022552254A5 JP2022552254A5 (https=) | 2023-10-20 |
| JPWO2021072372A5 true JPWO2021072372A5 (https=) | 2023-10-20 |
Family
ID=75438187
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022521217A Pending JP2022552254A (ja) | 2019-10-10 | 2020-10-12 | バリアントｉｇｆ２構築体 |
| JP2025167212A Pending JP2026021331A (ja) | 2019-10-10 | 2025-10-03 | バリアントｉｇｆ２構築体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025167212A Pending JP2026021331A (ja) | 2019-10-10 | 2025-10-03 | バリアントｉｇｆ２構築体 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20240091321A1 (https=) |
| EP (1) | EP4041284A4 (https=) |
| JP (2) | JP2022552254A (https=) |
| KR (1) | KR20220077921A (https=) |
| CN (1) | CN115087458A (https=) |
| AU (2) | AU2020361703A1 (https=) |
| BR (1) | BR112022006842A2 (https=) |
| CA (1) | CA3154189A1 (https=) |
| IL (1) | IL292065A (https=) |
| MX (1) | MX2022004345A (https=) |
| TW (1) | TW202128740A (https=) |
| WO (1) | WO2021072372A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20210005154A (ko) * | 2018-04-30 | 2021-01-13 | 아미쿠스 세라퓨틱스, 인코포레이티드 | 유전자 요법 작제물 및 사용 방법 |
| JP2023512423A (ja) | 2019-12-24 | 2023-03-27 | ジュベナ・セラピューティクス・インコーポレイテッド | 再生性ポリペプチドおよびその使用 |
| KR20230128001A (ko) | 2020-12-01 | 2023-09-01 | 더 트러스티스 오브 더 유니버시티 오브 펜실베니아 | 엔젤만 증후군의 치료를 위한 조성물 및 이의 용도 |
| KR20240029031A (ko) | 2021-06-21 | 2024-03-05 | 쥬베나 테라퓨틱스, 인크. | 재생 폴리펩티드 및 이의 용도 |
| US20240279360A1 (en) | 2021-06-23 | 2024-08-22 | Lycia Therapeutics, Inc. | Bifunctional compounds containing igf-2 polypeptides |
| AU2023303015A1 (en) * | 2022-07-06 | 2025-01-23 | Research Institute At Nationwide Children's Hospital | Adeno-associated virus delivery of cln1 polynucleotide |
| WO2024151982A1 (en) * | 2023-01-13 | 2024-07-18 | Amicus Therapeutics, Inc. | Gene therapy constructs for the treatment of pompe disease |
| WO2024196947A2 (en) * | 2023-03-20 | 2024-09-26 | Spark Therapeutics, Inc. | Ppt1 gene therapy |
| US20240360431A1 (en) * | 2023-04-30 | 2024-10-31 | Sichuan Real&Best Biotech Co., Ltd. | Engineered alpha-galactosidase a (a-gal a) peptides and functional variants thereof and associated methods of treating fabry disease |
| PL445164A1 (pl) * | 2023-06-07 | 2024-12-09 | Recepton Spółka Z Ograniczoną Odpowiedzialnością | Cząsteczki indukujące internalizację receptorów i białek zewnątrzkomórkowych |
| CN120025420A (zh) * | 2023-11-21 | 2025-05-23 | 深圳湾实验室 | 用于蛋白降解的构建体及其应用 |
| WO2025259950A1 (en) * | 2024-06-14 | 2025-12-18 | Cz Biohub Sf, Llc | Genetically encoded lysosome targeting chimeras for cell-mediated delivery |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE384736T1 (de) * | 2001-04-30 | 2008-02-15 | Zystor Therapeutics Inc | Subzelluläres targeting von therapeutischen proteinen |
| US7560424B2 (en) * | 2001-04-30 | 2009-07-14 | Zystor Therapeutics, Inc. | Targeted therapeutic proteins |
| CN1922313B (zh) * | 2004-02-10 | 2011-10-26 | 生物马林医药公司 | 酸性α-糖苷酶及其片段 |
| DK2241575T3 (en) * | 2005-01-07 | 2015-08-24 | Regeneron Pharma | IGF-1 fusion polypeptides and therapeutic uses thereof |
| LT2714752T (lt) * | 2011-05-27 | 2018-03-12 | Amicus Therapeutics, Inc. | Nukreipiančių peptidų kopuliavimo ant rekombinantinių lizosominių fermentų būdai, skirti lizosominio kaupimo ligų gydymo pagerinimui |
| WO2014082080A2 (en) * | 2012-11-26 | 2014-05-30 | Callidus Biopharma, Inc. | Methods for coupling targeting peptides onto recombinant lysosomal enzymes for improved treatments of lysosomal storage diseases |
| HUE039334T2 (hu) * | 2012-11-27 | 2018-12-28 | Biomarin Pharm Inc | Célzott terápiás lizoszómális enzim fúziós fehérjék és azok alkalmazásai |
| CN105189742A (zh) * | 2013-03-15 | 2015-12-23 | 阿米库斯治疗学公司 | 化学交联剂 |
| WO2016025523A1 (en) * | 2014-08-11 | 2016-02-18 | Shire Human Genetic Therapies, Inc. | Lysosomal targeting and uses thereof |
| EP3374504B1 (en) * | 2015-11-09 | 2025-03-19 | CureVac SE | Optimized nucleic acid molecules |
| AU2017315328A1 (en) * | 2016-08-24 | 2019-03-21 | Immunexpress Pty Ltd | Systemic inflammatory and pathogen biomarkers and uses therefor |
| KR20210005154A (ko) * | 2018-04-30 | 2021-01-13 | 아미쿠스 세라퓨틱스, 인코포레이티드 | 유전자 요법 작제물 및 사용 방법 |
| CN114127275A (zh) * | 2019-04-30 | 2022-03-01 | 宾夕法尼亚州大学信托人 | 可用于治疗庞贝病的组合物 |
-
2020
- 2020-10-12 CN CN202080081564.6A patent/CN115087458A/zh active Pending
- 2020-10-12 BR BR112022006842A patent/BR112022006842A2/pt not_active Application Discontinuation
- 2020-10-12 TW TW109135159A patent/TW202128740A/zh unknown
- 2020-10-12 EP EP20875073.7A patent/EP4041284A4/en active Pending
- 2020-10-12 KR KR1020227015116A patent/KR20220077921A/ko active Pending
- 2020-10-12 AU AU2020361703A patent/AU2020361703A1/en not_active Abandoned
- 2020-10-12 MX MX2022004345A patent/MX2022004345A/es unknown
- 2020-10-12 US US17/767,803 patent/US20240091321A1/en active Pending
- 2020-10-12 CA CA3154189A patent/CA3154189A1/en active Pending
- 2020-10-12 JP JP2022521217A patent/JP2022552254A/ja active Pending
- 2020-10-12 WO PCT/US2020/055251 patent/WO2021072372A1/en not_active Ceased
-
2022
- 2022-04-07 IL IL292065A patent/IL292065A/en unknown
-
2025
- 2025-02-01 AU AU2025200698A patent/AU2025200698A1/en active Pending
- 2025-10-03 JP JP2025167212A patent/JP2026021331A/ja active Pending
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