JPWO2021070494A5 - - Google Patents

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JPWO2021070494A5
JPWO2021070494A5 JP2021550425A JP2021550425A JPWO2021070494A5 JP WO2021070494 A5 JPWO2021070494 A5 JP WO2021070494A5 JP 2021550425 A JP2021550425 A JP 2021550425A JP 2021550425 A JP2021550425 A JP 2021550425A JP WO2021070494 A5 JPWO2021070494 A5 JP WO2021070494A5
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pmm
butyl
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JPWO2021070494A1 (https=
JP7640461B2 (ja
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JP2021550425A 2019-10-11 2020-08-25 核酸オリゴマーの製造方法 Active JP7640461B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2019187930 2019-10-11
JP2019187930 2019-10-11
PCT/JP2020/032020 WO2021070494A1 (ja) 2019-10-11 2020-08-25 核酸オリゴマーの製造方法

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JPWO2021070494A1 JPWO2021070494A1 (https=) 2021-04-15
JPWO2021070494A5 true JPWO2021070494A5 (https=) 2023-08-04
JP7640461B2 JP7640461B2 (ja) 2025-03-05

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JP2021550425A Active JP7640461B2 (ja) 2019-10-11 2020-08-25 核酸オリゴマーの製造方法

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US (1) US12509483B2 (https=)
EP (1) EP4043473A4 (https=)
JP (1) JP7640461B2 (https=)
KR (1) KR20220079832A (https=)
CN (1) CN114502566B (https=)
WO (1) WO2021070494A1 (https=)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20230312635A1 (en) * 2020-01-29 2023-10-05 Sumitomo Chemical Company, Limited Method for producing nucleic acid oligomer
JP7719788B2 (ja) * 2020-09-24 2025-08-06 住友化学株式会社 核酸オリゴマーの製造方法
CN118460647B (zh) * 2024-07-10 2025-01-28 凯莱英医药集团(天津)股份有限公司 一种Patisiran的制备方法
WO2026048956A1 (ja) * 2024-08-29 2026-03-05 住友化学株式会社 核酸オリゴマーの製造方法
WO2026071145A1 (ja) * 2024-09-30 2026-04-02 住友化学株式会社 核酸オリゴマーの製造方法

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US6077709A (en) 1998-09-29 2000-06-20 Isis Pharmaceuticals Inc. Antisense modulation of Survivin expression
DK1149109T3 (da) 1999-02-05 2010-01-11 Ge Healthcare Bio Sciences Fremgangsmåde til afbeskyttelse af oligonukleotider
US6261840B1 (en) 2000-01-18 2001-07-17 Isis Pharmaceuticals, Inc. Antisense modulation of PTP1B expression
WO2005007825A2 (en) * 2003-07-12 2005-01-27 Isis Pharmaceuticals, Inc. Modulation of aminopeptidase n expression
ES2386709T3 (es) 2004-08-26 2012-08-27 Nippon Shinyaku Co., Ltd. Compuesto de fosforamidita y método para producir un oligo-ARN
US8158775B2 (en) 2006-02-27 2012-04-17 Nippon Shinyaku Co., Ltd. Method for detaching protecting group on nucleic acid
WO2008049085A1 (en) 2006-10-18 2008-04-24 Isis Pharmaceuticals, Inc. Antisense compounds
EP2479182B8 (en) * 2009-09-16 2016-07-13 Wave Life Sciences Japan, Inc. Novel protecting group for synthesizing rna and derivative thereof
HUE037500T2 (hu) 2010-07-08 2018-08-28 Bonac Corp Egyszálú nukleinsav molekula a génexpresszió szabályozására
ES2527660T3 (es) 2010-08-03 2015-01-28 Bonac Corporation Molécula de ARN monocatenario que tiene esqueleto alicíclico que contiene nitrógeno
WO2013027843A1 (ja) 2011-08-25 2013-02-28 株式会社ボナック 配糖体化合物、チオエーテルの製造方法、エーテル、エーテルの製造方法、配糖体化合物の製造方法、核酸の製造方法
EP3241902B1 (en) 2012-05-25 2018-02-28 The Regents of The University of California Methods and compositions for rna-directed target dna modification and for rna-directed modulation of transcription
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KR102670605B1 (ko) 2018-04-24 2024-05-29 스미또모 가가꾸 가부시끼가이샤 아미다이트 화합물 및 그 화합물을 사용한 폴리뉴클레오티드의 제조 방법
JP7207682B2 (ja) 2018-04-26 2023-01-18 株式会社サンセイアールアンドディ 遊技機
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JP7719788B2 (ja) * 2020-09-24 2025-08-06 住友化学株式会社 核酸オリゴマーの製造方法

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