JPWO2021050649A5 - - Google Patents
Download PDFInfo
- Publication number
- JPWO2021050649A5 JPWO2021050649A5 JP2022515692A JP2022515692A JPWO2021050649A5 JP WO2021050649 A5 JPWO2021050649 A5 JP WO2021050649A5 JP 2022515692 A JP2022515692 A JP 2022515692A JP 2022515692 A JP2022515692 A JP 2022515692A JP WO2021050649 A5 JPWO2021050649 A5 JP WO2021050649A5
- Authority
- JP
- Japan
- Prior art keywords
- eye
- raav particles
- sequence
- unit dose
- administration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025077233A JP2025118798A (ja) | 2019-09-11 | 2025-05-07 | アフリベルセプトをコードするａａｖ２バリアントを使用して眼内血管新生疾患を処置する方法 |
Applications Claiming Priority (17)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962899070P | 2019-09-11 | 2019-09-11 | |
| US62/899,070 | 2019-09-11 | ||
| US201962913648P | 2019-10-10 | 2019-10-10 | |
| US62/913,648 | 2019-10-10 | ||
| USPCT/US2019/062066 | 2019-11-18 | ||
| PCT/US2019/062066 WO2021050094A1 (en) | 2019-09-11 | 2019-11-18 | Methods of treating ocular neovascular diseases using aav2 variants encoding aflibercept |
| US202062959784P | 2020-01-10 | 2020-01-10 | |
| US62/959,784 | 2020-01-10 | ||
| US202062971835P | 2020-02-07 | 2020-02-07 | |
| US62/971,835 | 2020-02-07 | ||
| US202063019190P | 2020-05-01 | 2020-05-01 | |
| US63/019,190 | 2020-05-01 | ||
| US202063030819P | 2020-05-27 | 2020-05-27 | |
| US63/030,819 | 2020-05-27 | ||
| US202063063203P | 2020-08-07 | 2020-08-07 | |
| US63/063,203 | 2020-08-07 | ||
| PCT/US2020/050079 WO2021050649A1 (en) | 2019-09-11 | 2020-09-10 | Methods of treating ocular neovascular diseases using aav2 variants encoding aflibercept |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025077233A Division JP2025118798A (ja) | 2019-09-11 | 2025-05-07 | アフリベルセプトをコードするａａｖ２バリアントを使用して眼内血管新生疾患を処置する方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022547541A JP2022547541A (ja) | 2022-11-14 |
| JP2022547541A5 JP2022547541A5 (https=) | 2023-08-24 |
| JPWO2021050649A5 true JPWO2021050649A5 (https=) | 2023-08-24 |
Family
ID=72644941
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022515692A Withdrawn JP2022547541A (ja) | 2019-09-11 | 2020-09-10 | アフリベルセプトをコードするａａｖ２バリアントを使用して眼内血管新生疾患を処置する方法 |
| JP2025077233A Pending JP2025118798A (ja) | 2019-09-11 | 2025-05-07 | アフリベルセプトをコードするａａｖ２バリアントを使用して眼内血管新生疾患を処置する方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025077233A Pending JP2025118798A (ja) | 2019-09-11 | 2025-05-07 | アフリベルセプトをコードするａａｖ２バリアントを使用して眼内血管新生疾患を処置する方法 |
Country Status (18)
| Country | Link |
|---|---|
| EP (2) | EP4027983B1 (https=) |
| JP (2) | JP2022547541A (https=) |
| KR (1) | KR20220062353A (https=) |
| CN (1) | CN114375195A (https=) |
| AU (1) | AU2020345915A1 (https=) |
| BR (1) | BR112022004027A2 (https=) |
| CA (1) | CA3148376A1 (https=) |
| DK (1) | DK4027983T3 (https=) |
| ES (1) | ES3063491T3 (https=) |
| FI (1) | FI4027983T3 (https=) |
| HR (1) | HRP20260137T1 (https=) |
| IL (1) | IL291182A (https=) |
| LT (1) | LT4027983T (https=) |
| MX (1) | MX2022002961A (https=) |
| PT (1) | PT4027983T (https=) |
| RS (1) | RS67774B1 (https=) |
| SM (1) | SMT202600070T1 (https=) |
| WO (1) | WO2021050649A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN118718181A (zh) | 2019-06-05 | 2024-10-01 | 里珍纳龙药品有限公司 | 用于精确剂量递送的装置及方法 |
| JP7842082B2 (ja) * | 2020-07-21 | 2026-04-07 | エフティージェン コーポレーション | 眼疾患を処置するための組成物および方法 |
| JP2024515459A (ja) | 2021-04-27 | 2024-04-10 | アドヴェラム バイオテクノロジーズ， インコーポレイテッド | アフリベルセプトをコードするａａｖ２バリアントを使用する眼疾患の治療方法 |
| MX2023014041A (es) * | 2021-05-28 | 2023-12-15 | Shanghai Regenelead Therapies Co Ltd | Virus adenoasociado recombinante que tiene una capsida variante y su aplicacion. |
| WO2023028457A1 (en) * | 2021-08-23 | 2023-03-02 | Duke University | Compositions for and methods of long-term integration of circuits using connexins |
| EP4479098A1 (en) * | 2022-02-16 | 2024-12-25 | Adverum Biotechnologies, Inc. | Method of reducing cst fluctuation in neovascular amd by a recombinant adeno-associated virus |
| USD1120314S1 (en) | 2022-11-30 | 2026-03-24 | Regeneron Pharmaceuticals, Inc. | Dose delivery device |
| WO2025026182A1 (zh) | 2023-08-01 | 2025-02-06 | 北京因诺惟康医药科技有限公司 | 融合多肽、包含其编码基因的表达盒、基因递送载体、药物组合物及用途 |
| KR20260004635A (ko) * | 2024-07-01 | 2026-01-09 | 삼성바이오에피스 주식회사 | 애플리버셉트를 암호화하는 코돈-최적화된 폴리뉴클레오티드를 포함하는 발현 카세트 및 이를 포함하는 rAAV 생산용 플라스미드 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2544136B2 (ja) * | 1986-05-23 | 1996-10-16 | 第一製薬株式会社 | 硫酸化多糖体ｄｓ４１５２を含有する血管新生抑制剤及び抗腫瘍剤 |
| TW201105363A (en) * | 2009-07-14 | 2011-02-16 | Univ Yamagata | Eye drop for macular edema treatment |
| HRP20171334T1 (hr) | 2011-04-22 | 2017-11-17 | The Regents Of The University Of California | Virioni adeno-povezanog virusa s kapsid varijantom i postupci njihove upotrebe |
| AU2014252808A1 (en) * | 2013-04-09 | 2015-11-12 | Cresset Biomolecular Discovery Ltd | The treatment of inflammatory disorders |
| DK3471780T3 (da) * | 2016-06-16 | 2020-11-23 | Adverum Biotechnologies Inc | Behandling af amd med aav2-variant med aflibercept |
| CN110546257B (zh) | 2017-03-17 | 2024-03-01 | 阿德夫拉姆生物技术股份有限公司 | 用于增强基因表达的组合物和方法 |
-
2020
- 2020-09-10 FI FIEP20780467.5T patent/FI4027983T3/fi active
- 2020-09-10 KR KR1020227011745A patent/KR20220062353A/ko active Pending
- 2020-09-10 AU AU2020345915A patent/AU2020345915A1/en active Pending
- 2020-09-10 DK DK20780467.5T patent/DK4027983T3/da active
- 2020-09-10 PT PT207804675T patent/PT4027983T/pt unknown
- 2020-09-10 RS RS20260196A patent/RS67774B1/sr unknown
- 2020-09-10 LT LTEPPCT/US2020/050079T patent/LT4027983T/lt unknown
- 2020-09-10 JP JP2022515692A patent/JP2022547541A/ja not_active Withdrawn
- 2020-09-10 MX MX2022002961A patent/MX2022002961A/es unknown
- 2020-09-10 SM SM20260070T patent/SMT202600070T1/it unknown
- 2020-09-10 WO PCT/US2020/050079 patent/WO2021050649A1/en not_active Ceased
- 2020-09-10 EP EP20780467.5A patent/EP4027983B1/en active Active
- 2020-09-10 BR BR112022004027A patent/BR112022004027A2/pt unknown
- 2020-09-10 ES ES20780467T patent/ES3063491T3/es active Active
- 2020-09-10 CA CA3148376A patent/CA3148376A1/en active Pending
- 2020-09-10 CN CN202080063266.4A patent/CN114375195A/zh active Pending
- 2020-09-10 EP EP25180005.8A patent/EP4696318A1/en active Pending
- 2020-09-10 HR HRP20260137TT patent/HRP20260137T1/hr unknown
-
2022
- 2022-03-08 IL IL291182A patent/IL291182A/en unknown
-
2025
- 2025-05-07 JP JP2025077233A patent/JP2025118798A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP7492556B2 (ja) | 滲出型加齢性黄斑変性の治療のための組成物 | |
| FI4027983T3 (fi) | Silmän neovaskulaaristen sairauksien hoito afliberseptiä koodaavilla aav2-varianteilla | |
| JP2021503914A5 (https=) | ||
| US20240108669A1 (en) | Adeno-associated virus vector pharmaceutical composition and methods | |
| RU2018142768A (ru) | Варианты капсидов аденоассоциированного вируса и способы их применения | |
| FI3717636T3 (fi) | Adenoassosioidun viruksen kapsidivariantteja ja käyttö angiogeneesin estämisessä | |
| US20110117189A1 (en) | Ophthalmic compositions for treating pathologies of the posterior segment of the eye | |
| CA3091250A1 (en) | Non-viral dna vectors and uses thereof for antibody and fusion protein production | |
| JP2021511030A5 (https=) | ||
| JPWO2021050649A5 (https=) | ||
| US20200297869A1 (en) | Sequential intravitreal administration of aav gene therapy to contralateral eyes | |
| US20220323587A1 (en) | Dissolvable films and methods of their use | |
| KR20230131246A (ko) | 파브리병을 치료하기 위한 조성물 및 방법 | |
| US20160324986A1 (en) | Compositions and methods for providing active telomerase to cells in vivo | |
| JPWO2022232790A5 (https=) | ||
| JPWO2023150566A5 (https=) | ||
| JPWO2023158990A5 (https=) | ||
| JP7766054B2 (ja) | 眼病態の処置のためのｄｎａ構造 | |
| JPWO2021041373A5 (https=) | ||
| Kirkner | Pipeline report: new entries continue to exceed exits | |
| Chan | Association for Research in Vision and Ophthalmology (ARVO) 2017 Annual Meeting. Baltimore, Maryland, USA-May 7-11, 2017 | |
| JPWO2020236352A5 (https=) | ||
| Toprak | ANTI-VEGF AND STEROID THERAPY IN DIABETIC RETINOPATHY | |
| JPWO2021069523A5 (https=) | ||
| RU2025139063A (ru) | Препараты аденоассоциированных вирусов |