JPWO2021011903A5 - - Google Patents

Download PDF

Info

Publication number
JPWO2021011903A5
JPWO2021011903A5 JP2022503450A JP2022503450A JPWO2021011903A5 JP WO2021011903 A5 JPWO2021011903 A5 JP WO2021011903A5 JP 2022503450 A JP2022503450 A JP 2022503450A JP 2022503450 A JP2022503450 A JP 2022503450A JP WO2021011903 A5 JPWO2021011903 A5 JP WO2021011903A5
Authority
JP
Japan
Prior art keywords
sequence
seq
fragment
antibody
light chain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022503450A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022541275A (ja
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/042627 external-priority patent/WO2021011903A1/en
Publication of JP2022541275A publication Critical patent/JP2022541275A/ja
Publication of JPWO2021011903A5 publication Critical patent/JPWO2021011903A5/ja
Pending legal-status Critical Current

Links

JP2022503450A 2019-07-17 2020-07-17 H因子増強性抗体及びその使用 Pending JP2022541275A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962875309P 2019-07-17 2019-07-17
US62/875,309 2019-07-17
PCT/US2020/042627 WO2021011903A1 (en) 2019-07-17 2020-07-17 Factor h potentiating antibodies and uses thereof

Publications (2)

Publication Number Publication Date
JP2022541275A JP2022541275A (ja) 2022-09-22
JPWO2021011903A5 true JPWO2021011903A5 (es) 2023-07-19

Family

ID=74211270

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022503450A Pending JP2022541275A (ja) 2019-07-17 2020-07-17 H因子増強性抗体及びその使用

Country Status (13)

Country Link
US (1) US11820814B2 (es)
EP (1) EP3999073A4 (es)
JP (1) JP2022541275A (es)
KR (1) KR20220057530A (es)
CN (1) CN114828886A (es)
AR (1) AR122286A1 (es)
AU (1) AU2020313981A1 (es)
BR (1) BR112022000739A2 (es)
CA (1) CA3147638A1 (es)
IL (1) IL289812A (es)
MX (1) MX2022000725A (es)
TW (1) TW202110893A (es)
WO (1) WO2021011903A1 (es)

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5530101A (en) * 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
WO2003080672A1 (en) 2002-03-22 2003-10-02 Aprogen, Inc. Humanized antibody and process for preparing same
US20090004183A1 (en) 2004-07-23 2009-01-01 Taylor Ronald P Compositions and Methods for Regulating the Alternative Pathway of Complement
KR20170002684A (ko) 2005-11-04 2017-01-06 제넨테크, 인크. 안질환 치료를 위한 보체 경로 억제제의 용도
FR2894145B1 (fr) 2005-12-07 2008-10-17 Lab Francais Du Fractionnement Utilisation de facteur h du complement a titre de medicament
KR20150029002A (ko) 2007-06-07 2015-03-17 제넨테크, 인크. 보체-관련 장애의 예방 및 치료를 위한 C3b 항체 및 방법
GB0819633D0 (en) 2008-10-25 2008-12-03 Isis Innovation Composition
JP2013508287A (ja) 2009-10-14 2013-03-07 ヤンセン バイオテツク,インコーポレーテツド 抗体を親和性成熟する方法
CA2780221A1 (en) 2009-11-04 2011-05-12 Fabrus Llc Methods for affinity maturation-based antibody optimization
US9295713B2 (en) 2010-09-15 2016-03-29 Celldex Therapeutics, Inc. Treatment of chronic nephropathies using soluble complement receptor type I (sCR1)
WO2013078223A1 (en) * 2011-11-23 2013-05-30 Children's Hospital & Research Center Oakland Anti-factor h binding protein antibodies and methods of use thereof
US9926366B2 (en) 2012-10-04 2018-03-27 Novelmed Therapeutics, Inc. Methods of treating a hemolytic disorder comprising administering anti-properdin antibodies
GB201318170D0 (en) * 2013-10-14 2013-11-27 Univ Edinburgh Proteins with Diagnostic and Therapeutic Uses
EP3066132A2 (en) 2013-11-07 2016-09-14 Novo Nordisk A/S Novel methods and antibodies for treating coagulapathy
US10357554B2 (en) 2013-11-11 2019-07-23 The United States Of America, As Represented By The Secretary Of The Army AMA-1 epitopes, antibodies, compositions, and methods of making and using the same
CN107074939B (zh) 2014-08-20 2021-09-07 桑昆血液供给基金会 H因子增强抗体及其用途
BR112017003582B1 (pt) 2014-08-27 2024-01-09 Memorial Sloan Kettering Cancer Center Agente de anticorpo, uso do mesmo, composição farmacêutica e receptor de antígeno quimérico
WO2017114401A1 (zh) * 2015-12-31 2017-07-06 江苏匡亚生物医药科技有限公司 具有补体调节活性的重组补体因子h-免疫球蛋白融合蛋白及其制备方法与应用
CR20180529A (es) * 2016-04-04 2019-03-21 Bioverativ Usa Inc Anticuerpos anti-factor bb del complemento y usos de estos referencia cruzada
GB201608046D0 (en) * 2016-05-09 2016-06-22 Cambridge Entpr Ltd And Syndey Children S Hospitals Network Randwick And Westmead Incorporating The Treatment of complement-mediated disorders
US20190202878A1 (en) * 2016-06-28 2019-07-04 Universitat Ulm Complement inhibitors and uses thereof
US10865238B1 (en) * 2017-05-05 2020-12-15 Duke University Complement factor H antibodies
KR20200110688A (ko) * 2018-01-15 2020-09-24 스티흐팅 산퀸 불드포르지닝 인자 h 강화 항체 및 이의 사용

Similar Documents

Publication Publication Date Title
US20200172605A1 (en) Gene therapy for alzheimer's and other neurodegenerative diseases and conditions
US10875910B2 (en) Antibodies recognizing alpha-synuclein
JP2019527543A5 (es)
JP6342333B2 (ja) α−シヌクレインを認識するヒト化抗体
JP2010538608A5 (es)
JP2019527194A5 (es)
RU2009128064A (ru) Антитела к cd44
JP7410522B2 (ja) 抗fam19a5抗体のアデノ関連ウイルス(aav)伝達
JP2020536532A5 (es)
WO2014052693A2 (en) Veterinary composition and methods for non-surgical neutering and castration
JP2019511911A5 (es)
JP2023089191A5 (es)
JP2021510523A5 (es)
WO2020160337A1 (en) Systems for evolved adeno-associated viruses (aavs) for targeted delivery
CN113354730B (zh) 一种抗新型冠状病毒的单克隆抗体及其应用
EP3253792A1 (en) Anti-tau constructs
US20160355581A1 (en) Compositions and methods for treating amyloid plaque associated symptoms
RU2018131123A (ru) Антитела к tgf-бета2
CN110540590A (zh) 一种自免疫抑制物的开发和应用
BRPI0612734A2 (pt) anticorpo monoclonal, composição farmacêutica, métodos de promoção de brotamento axonal, e de produção de um anticorpo anti-nogo, e, uso de um anticorpo anti-nogo
JPWO2021011903A5 (es)
JP2019514343A5 (es)
JP2023522212A (ja) 治療用musk抗体
RU2380377C2 (ru) Nogo-A-СВЯЗЫВАЮЩИЕ МОЛЕКУЛЫ И ИХ ФАРМАЦЕВТИЧЕСКОЕ ПРИМЕНЕНИЕ
RU2022103907A (ru) Антитела, активирующие фактор н, и их применение