JPWO2020225577A5 - - Google Patents
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- Publication number
- JPWO2020225577A5 JPWO2020225577A5 JP2021566259A JP2021566259A JPWO2020225577A5 JP WO2020225577 A5 JPWO2020225577 A5 JP WO2020225577A5 JP 2021566259 A JP2021566259 A JP 2021566259A JP 2021566259 A JP2021566259 A JP 2021566259A JP WO2020225577 A5 JPWO2020225577 A5 JP WO2020225577A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- referred
- cysteine residues
- amino acids
- peptide ligand
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962845473P | 2019-05-09 | 2019-05-09 | |
| US62/845,473 | 2019-05-09 | ||
| PCT/GB2020/051144 WO2020225577A1 (en) | 2019-05-09 | 2020-05-11 | Bicyclic peptide ligands specific for ox40 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022532134A JP2022532134A (ja) | 2022-07-13 |
| JPWO2020225577A5 true JPWO2020225577A5 (hr) | 2023-05-17 |
Family
ID=70847426
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021566259A Pending JP2022532134A (ja) | 2019-05-09 | 2020-05-11 | Ｏｘ４０に特異的な二環式ペプチドリガンド |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US11613560B2 (hr) |
| EP (1) | EP3965827A1 (hr) |
| JP (1) | JP2022532134A (hr) |
| KR (1) | KR20220007098A (hr) |
| CN (1) | CN113811541A (hr) |
| AU (1) | AU2020269506A1 (hr) |
| BR (1) | BR112021022315A2 (hr) |
| CA (1) | CA3137095A1 (hr) |
| IL (1) | IL287881A (hr) |
| MX (1) | MX2021013669A (hr) |
| SG (1) | SG11202111606TA (hr) |
| WO (1) | WO2020225577A1 (hr) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019025811A1 (en) | 2017-08-04 | 2019-02-07 | Bicycletx Limited | SPECIFIC BICYCLIC PEPTIDE LIGANDS OF CD137 |
| TWI825046B (zh) | 2017-12-19 | 2023-12-11 | 英商拜西可泰克斯有限公司 | Epha2特用之雙環胜肽配位基 |
| GB201810316D0 (en) | 2018-06-22 | 2018-08-08 | Bicyclerd Ltd | Peptide ligands for binding to EphA2 |
| US11180531B2 (en) | 2018-06-22 | 2021-11-23 | Bicycletx Limited | Bicyclic peptide ligands specific for Nectin-4 |
| JP2022532134A (ja) | 2019-05-09 | 2022-07-13 | バイスクルテクス・リミテッド | Ｏｘ４０に特異的な二環式ペプチドリガンド |
| TW202118770A (zh) | 2019-07-30 | 2021-05-16 | 英商拜西可泰克斯有限公司 | 異質雙環肽複合物 |
| EP4038096A1 (en) | 2019-10-03 | 2022-08-10 | BicycleTX Limited | Heterotandem bicyclic peptide complexes |
| US20240197897A1 (en) * | 2021-01-08 | 2024-06-20 | Bicycle TX Limited | Heterotandem bicyclic peptide complexes |
| AU2022356942A1 (en) * | 2021-09-29 | 2024-05-09 | Conjustar (Zhuhai) Biologics Co., Ltd. | Tricyclic polypeptide conjugated drug and use thereof |
| CN114933638B (zh) * | 2022-05-12 | 2024-07-26 | 厦门大学 | 特异性靶向cd28的多元环肽配体框架 |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6927203B1 (en) | 1999-08-17 | 2005-08-09 | Purdue Research Foundation | Treatment of metastatic disease |
| EP1452868A2 (en) | 2003-02-27 | 2004-09-01 | Pepscan Systems B.V. | Method for selecting a candidate drug compound |
| ES2383191T3 (es) | 2008-02-05 | 2012-06-19 | Medical Research Council | Métodos y composiciones |
| GB0913775D0 (en) | 2009-08-06 | 2009-09-16 | Medical Res Council | Multispecific peptides |
| WO2012057624A1 (en) | 2010-10-25 | 2012-05-03 | Pepscan Systems B.V. | Novel bicyclic peptide mimetics |
| ES2740358T3 (es) * | 2012-02-06 | 2020-02-05 | Providence Health & Services Oregon | Método de supervisión del tratamiento del cáncer con agonistas de OX40 |
| EP2999483B1 (en) | 2013-05-23 | 2018-10-31 | Ohio State Innovation Foundation | Chemical synthesis and screening of bicyclic peptide libraries |
| RS59119B1 (sr) | 2014-05-21 | 2019-09-30 | Entrada Therapeutics Inc | Peptidi koji prodiru u ćelije i postupci za njihovo pravljenje i upotrebu |
| SI3215518T1 (sl) * | 2014-10-29 | 2021-08-31 | Bicyclerd Limited | Biciklični peptidni ligandi, značilni za MT1-MMP |
| US10682390B2 (en) * | 2015-07-16 | 2020-06-16 | Biokine Therapeutics Ltd. | Compositions and methods for treating cancer |
| MA45328A (fr) | 2016-04-01 | 2019-02-06 | Avidity Biosciences Llc | Compositions acide nucléique-polypeptide et utilisations de celles-ci |
| CA3021618A1 (en) | 2016-04-22 | 2017-10-26 | Alligator Bioscience Ab | Novel bispecific polypeptides against cd137 |
| GB201607827D0 (en) * | 2016-05-04 | 2016-06-15 | Bicycle Therapeutics Ltd | Bicyclic peptide-toxin conjugates specific for MT1-MMP |
| JP2020502238A (ja) | 2016-12-23 | 2020-01-23 | バイスクルアールディー・リミテッド | 新規連結構造を有するペプチド誘導体 |
| US11459394B2 (en) | 2017-02-24 | 2022-10-04 | Macrogenics, Inc. | Bispecific binding molecules that are capable of binding CD137 and tumor antigens, and uses thereof |
| WO2019025811A1 (en) | 2017-08-04 | 2019-02-07 | Bicycletx Limited | SPECIFIC BICYCLIC PEPTIDE LIGANDS OF CD137 |
| GB201721265D0 (en) | 2017-12-19 | 2018-01-31 | Bicyclerd Ltd | Bicyclic peptide ligands specific for EphA2 |
| TWI825046B (zh) | 2017-12-19 | 2023-12-11 | 英商拜西可泰克斯有限公司 | Epha2特用之雙環胜肽配位基 |
| MX2020008791A (es) | 2018-02-23 | 2021-01-08 | Bicycletx Ltd | Ligandos de peptidos biciclicos multimericos. |
| KR20200139236A (ko) | 2018-04-04 | 2020-12-11 | 바이사이클티엑스 리미티드 | 헤테로탠덤 비사이클릭 펩티드 복합체 |
| GB201810316D0 (en) | 2018-06-22 | 2018-08-08 | Bicyclerd Ltd | Peptide ligands for binding to EphA2 |
| US11180531B2 (en) | 2018-06-22 | 2021-11-23 | Bicycletx Limited | Bicyclic peptide ligands specific for Nectin-4 |
| JP2022512779A (ja) | 2018-10-23 | 2022-02-07 | バイスクルテクス・リミテッド | 二環式ペプチドリガンドおよびその使用 |
| WO2020128526A1 (en) | 2018-12-21 | 2020-06-25 | Bicycletx Limited | Bicyclic peptide ligands specific for pd-l1 |
| AU2020253990A1 (en) | 2019-04-02 | 2021-10-28 | Bicycletx Limited | Bicycle toxin conjugates and uses thereof |
| JP2022532134A (ja) | 2019-05-09 | 2022-07-13 | バイスクルテクス・リミテッド | Ｏｘ４０に特異的な二環式ペプチドリガンド |
| TW202118770A (zh) | 2019-07-30 | 2021-05-16 | 英商拜西可泰克斯有限公司 | 異質雙環肽複合物 |
| EP4038096A1 (en) | 2019-10-03 | 2022-08-10 | BicycleTX Limited | Heterotandem bicyclic peptide complexes |
| MX2022006001A (es) | 2019-11-27 | 2022-10-27 | Bicycletx Ltd | Ligandos de peptidos biciclicos especificos para el receptor 2 tipo a de efrina (epha2) y usos de los mismos. |
| IL298868A (en) | 2020-06-12 | 2023-02-01 | Bicycletx Ltd | Treatment of diseases characterized by overexpression of hepatocyte receptor A2 that produces erythropoietin (EPHA2) |
-
2020
- 2020-05-11 JP JP2021566259A patent/JP2022532134A/ja active Pending
- 2020-05-11 CN CN202080033959.9A patent/CN113811541A/zh active Pending
- 2020-05-11 WO PCT/GB2020/051144 patent/WO2020225577A1/en unknown
- 2020-05-11 AU AU2020269506A patent/AU2020269506A1/en not_active Abandoned
- 2020-05-11 SG SG11202111606TA patent/SG11202111606TA/en unknown
- 2020-05-11 EP EP20728128.8A patent/EP3965827A1/en active Pending
- 2020-05-11 MX MX2021013669A patent/MX2021013669A/es unknown
- 2020-05-11 CA CA3137095A patent/CA3137095A1/en active Pending
- 2020-05-11 BR BR112021022315A patent/BR112021022315A2/pt unknown
- 2020-05-11 KR KR1020217039675A patent/KR20220007098A/ko unknown
- 2020-05-11 US US16/872,097 patent/US11613560B2/en active Active
-
2021
- 2021-11-07 IL IL287881A patent/IL287881A/en unknown
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