|
US5516931A
(en)
|
1982-02-01 |
1996-05-14 |
Northeastern University |
Release tag compounds producing ketone signal groups
|
|
US4650750A
(en)
|
1982-02-01 |
1987-03-17 |
Giese Roger W |
Method of chemical analysis employing molecular release tag compounds
|
|
US5650270A
(en)
|
1982-02-01 |
1997-07-22 |
Northeastern University |
Molecular analytical release tags and their use in chemical analysis
|
|
US4709016A
(en)
|
1982-02-01 |
1987-11-24 |
Northeastern University |
Molecular analytical release tags and their use in chemical analysis
|
|
US5595756A
(en)
|
1993-12-22 |
1997-01-21 |
Inex Pharmaceuticals Corporation |
Liposomal compositions for enhanced retention of bioactive agents
|
|
US20020164788A1
(en)
|
1994-12-02 |
2002-11-07 |
The Wellcome Foundation Limited |
Humanized antibodies to CD38
|
|
US6326144B1
(en)
|
1998-09-18 |
2001-12-04 |
Massachusetts Institute Of Technology |
Biological applications of quantum dots
|
|
AU3468500A
(en)
|
1998-09-24 |
2000-06-05 |
Advanced Research And Technology Institute, Inc. |
Water-soluble luminescent quantum dots and biomolecular conjugates thereof and related compositions and methods of use
|
|
US6927203B1
(en)
*
|
1999-08-17 |
2005-08-09 |
Purdue Research Foundation |
Treatment of metastatic disease
|
|
TR200400105T4
(tr)
|
1999-12-10 |
2004-02-23 |
Prizer Products Inc. |
Pirrolo [2,3-d] pirimidin bileşikleri
|
|
US7071189B2
(en)
|
2001-04-27 |
2006-07-04 |
Zenyaku Kogyo Kabushiki Kaisha |
Heterocyclic compound and antitumor agent containing the same as active ingredient
|
|
TWI329105B
(en)
|
2002-02-01 |
2010-08-21 |
Rigel Pharmaceuticals Inc |
2,4-pyrimidinediamine compounds and their uses
|
|
AU2003217606C1
(en)
|
2002-02-21 |
2008-07-17 |
Institute Of Virology |
Soluble Form of Carbonic Anhydrase IX (s-CA IX), Assays to Detect s-CA IX, CA IXs Coexpression with HER-2/neu/c-erbB-2 and CA IX-Specific Monoclonal Antibodies to Non-Immunodominant Epitopes
|
|
BRPI0313733A8
(pt)
|
2002-08-14 |
2016-08-16 |
Atugen Ag |
Uso da proteína n beta cinase
|
|
EP1452868A2
(en)
|
2003-02-27 |
2004-09-01 |
Pepscan Systems B.V. |
Method for selecting a candidate drug compound
|
|
AU2004228668B2
(en)
|
2003-04-03 |
2011-10-27 |
Park Funding, Llc |
PI-3 kinase inhibitor prodrugs
|
|
WO2005007623A2
(en)
|
2003-07-03 |
2005-01-27 |
The Trustees Of The University Of Pennsylvania |
Inhibition of syk kinase expression
|
|
RS54056B1
(en)
|
2004-02-06 |
2015-10-30 |
Morphosys Ag |
ANTI-CD38 HUMAN ANTIBODIES AND THEIR USES
|
|
US7151047B2
(en)
|
2004-04-28 |
2006-12-19 |
Warren Chan |
Stable, water-soluble quantum dot, method of preparation and conjugates thereof
|
|
EP1761540B1
(en)
|
2004-05-13 |
2016-09-28 |
Icos Corporation |
Quinazolinones as inhibitors of human phosphatidylinositol 3-kinase delta
|
|
CA2591948C
(en)
|
2005-01-19 |
2013-11-12 |
Rigel Pharmaceuticals, Inc. |
Prodrugs of 2,4-pyrimidinediamine compounds and their uses
|
|
NZ560504A
(en)
|
2005-01-24 |
2009-07-31 |
Pepscan Systems Bv |
Binding compounds, immunogenic compounds and peptidomimetics
|
|
GB0510390D0
(en)
|
2005-05-20 |
2005-06-29 |
Novartis Ag |
Organic compounds
|
|
US7402325B2
(en)
|
2005-07-28 |
2008-07-22 |
Phoenix Biotechnology, Inc. |
Supercritical carbon dioxide extract of pharmacologically active components from Nerium oleander
|
|
KR101504994B1
(ko)
|
2005-10-07 |
2015-03-23 |
엑셀리시스, 인코포레이티드 |
포스파티딜이노시톨 3-키나아제 억제제 및 이의 사용 방법
|
|
EP1951684B1
(en)
|
2005-11-01 |
2016-07-13 |
TargeGen, Inc. |
Bi-aryl meta-pyrimidine inhibitors of kinases
|
|
ES2611588T3
(es)
|
2005-12-13 |
2017-05-09 |
Incyte Holdings Corporation |
Pirrolo[2,3-b]piridinas y pirrolo[2,3-b]pirimidinas sustituidas con heteroarilo como inhibidores de quinasas Janus
|
|
JO2660B1
(en)
|
2006-01-20 |
2012-06-17 |
نوفارتيس ايه جي |
Pi-3 inhibitors and methods of use
|
|
PT2024372E
(pt)
|
2006-04-26 |
2010-09-16 |
Hoffmann La Roche |
Derivado de tieno[3,2-d]pirimidina útil como inibidor de pi3k
|
|
US7666392B2
(en)
|
2006-09-15 |
2010-02-23 |
Siemens Medical Solutions Usa, Inc. |
Click chemistry-derived cyclopeptide derivatives as imaging agents for integrins
|
|
CN102887900B
(zh)
|
2006-09-22 |
2015-04-29 |
药品循环公司 |
布鲁顿酪氨酸激酶的抑制剂
|
|
KR101737753B1
(ko)
|
2007-03-12 |
2017-05-18 |
와이엠 바이오사이언시즈 오스트레일리아 피티와이 엘티디 |
페닐 아미노 피리미딘 화합물 및 이의 용도
|
|
PE20090717A1
(es)
|
2007-05-18 |
2009-07-18 |
Smithkline Beecham Corp |
Derivados de quinolina como inhibidores de la pi3 quinasa
|
|
KR20100056438A
(ko)
|
2007-06-18 |
2010-05-27 |
메디뮨 엘엘씨 |
ＥｐｈＡ2 및 ＥｒｂＢ2를 발현하는 세포의 상승적 치료 방법
|
|
EP2653544A1
(en)
|
2008-02-05 |
2013-10-23 |
Bicycle Therapeutics Limited |
Methods and compositions
|
|
SG191660A1
(en)
|
2008-03-11 |
2013-07-31 |
Incyte Corp |
Azetidine and cyclobutane derivatives as jak inhibitors
|
|
US8338439B2
(en)
|
2008-06-27 |
2012-12-25 |
Celgene Avilomics Research, Inc. |
2,4-disubstituted pyrimidines useful as kinase inhibitors
|
|
GB0913775D0
(en)
|
2009-08-06 |
2009-09-16 |
Medical Res Council |
Multispecific peptides
|
|
GB0914110D0
(en)
|
2009-08-12 |
2009-09-16 |
Medical Res Council |
Peptide libraries
|
|
WO2012057624A1
(en)
|
2010-10-25 |
2012-05-03 |
Pepscan Systems B.V. |
Novel bicyclic peptide mimetics
|
|
GB201117428D0
(en)
|
2011-10-07 |
2011-11-23 |
Bicycle Therapeutics Ltd |
Structured polypeptides with sarcosine linkers
|
|
DK2764140T3
(en)
|
2011-10-07 |
2017-12-04 |
Bicyclerd Ltd |
MODULATION OF STRUCTURED POLYPEPTIME SPECIFICITY
|
|
KR101990341B1
(ko)
|
2013-03-12 |
2019-06-19 |
몰레큘러 템플레이츠, 인코퍼레이션. |
세포 내재화를 유도하기 위한 ｃｄ20-결합 면역독소 및 이의 사용 방법
|
|
US20140274759A1
(en)
|
2013-03-15 |
2014-09-18 |
Bicycle Therapeutics Limited |
Modification of polypeptides
|
|
GB201306623D0
(en)
|
2013-04-11 |
2013-05-29 |
Bicycle Therapeutics Ltd |
Modulation of structured polypeptide specificity
|
|
WO2014190257A2
(en)
|
2013-05-23 |
2014-11-27 |
Ohio State Innovation Foundation |
Chemical synthesis and screening of bicyclic peptide libraries
|
|
WO2015063465A2
(en)
|
2013-10-28 |
2015-05-07 |
Bicycle Therapeutics Limited |
Novel polypeptides
|
|
CN106415269B
(zh)
|
2014-05-08 |
2020-11-27 |
贵州美鑫达医疗科技有限公司 |
直接免疫组织化学测定
|
|
HUE045872T2
(hu)
|
2014-05-21 |
2020-01-28 |
Entrada Therapeutics Inc |
Sejteket penetráló peptidek és ezek elõállítására és alkalmazására szolgáló eljárások
|
|
AU2015340300B2
(en)
|
2014-10-29 |
2019-12-05 |
Bicyclerd Limited |
Bicyclic peptide ligands specific for MT1-MMP
|
|
WO2016171242A1
(ja)
|
2015-04-24 |
2016-10-27 |
第一三共株式会社 |
Ｅｐｈａ２の検出
|
|
MX2017013892A
(es)
|
2015-04-28 |
2018-06-06 |
Ecole Polytechnique Fed Lausanne Epfl |
Inhibidores novedosos del factor xii activado por la enzima (fxiia).
|
|
EP3429630A1
(en)
|
2016-03-16 |
2019-01-23 |
Merrimack Pharmaceuticals, Inc. |
Nanoliposomal targeting of ephrin receptor a2 (epha2) and related diagnosticss
|
|
MA45328A
(fr)
|
2016-04-01 |
2019-02-06 |
Avidity Biosciences Llc |
Compositions acide nucléique-polypeptide et utilisations de celles-ci
|
|
WO2017182672A1
(en)
|
2016-04-22 |
2017-10-26 |
Alligator Bioscience Ab |
Novel bispecific polypeptides against cd137
|
|
GB201607827D0
(en)
|
2016-05-04 |
2016-06-15 |
Bicycle Therapeutics Ltd |
Bicyclic peptide-toxin conjugates specific for MT1-MMP
|
|
WO2018096365A1
(en)
|
2016-11-27 |
2018-05-31 |
Bicyclerd Limited |
Methods for treating cancer
|
|
US11730819B2
(en)
|
2016-12-23 |
2023-08-22 |
Bicycletx Limited |
Peptide derivatives having novel linkage structures
|
|
KR20230042153A
(ko)
|
2016-12-23 |
2023-03-27 |
바이사이클티엑스 리미티드 |
Ｍｔ１－ｍｍｐ에 대한 결합용 펩티드 리간드
|
|
WO2018127699A1
(en)
|
2017-01-06 |
2018-07-12 |
Bicyclerd Limited |
Compounds for treating cancer
|
|
US11459394B2
(en)
|
2017-02-24 |
2022-10-04 |
Macrogenics, Inc. |
Bispecific binding molecules that are capable of binding CD137 and tumor antigens, and uses thereof
|
|
GB201706477D0
(en)
|
2017-04-24 |
2017-06-07 |
Bicycle Therapeutics Ltd |
Modification of polypeptides
|
|
US10857196B2
(en)
|
2017-04-27 |
2020-12-08 |
Bicycletx Limited |
Bicyclic peptide ligands and uses thereof
|
|
JP7301757B2
(ja)
|
2017-06-26 |
2023-07-03 |
バイスクルアールディー・リミテッド |
検出可能部分を持つ二環式ペプチドリガンドおよびその使用
|
|
EP3661948B1
(en)
|
2017-08-04 |
2022-06-01 |
BicycleTx Limited |
Bicyclic peptide ligands specific for cd137
|
|
EP3668550A1
(en)
|
2017-08-14 |
2020-06-24 |
Bicyclerd Limited |
Bicyclic peptide ligand prr-a conjugates and uses thereof
|
|
US20200291096A1
(en)
|
2017-08-14 |
2020-09-17 |
Bicyclerd Limited |
Bicyclic peptide ligand sting conjugates and uses thereof
|
|
TWI825046B
(zh)
|
2017-12-19 |
2023-12-11 |
英商拜西可泰克斯有限公司 |
Epha2特用之雙環胜肽配位基
|
|
GB201721265D0
(en)
|
2017-12-19 |
2018-01-31 |
Bicyclerd Ltd |
Bicyclic peptide ligands specific for EphA2
|
|
WO2019136442A1
(en)
|
2018-01-08 |
2019-07-11 |
Kleo Pharmaceuticals, Inc. |
Cd16a binding agents and uses thereof
|
|
BR112020014576A2
(pt)
|
2018-02-23 |
2020-12-08 |
Bicycletx Limited |
Ligantes peptídicos bicíclicos multiméricos
|
|
US11453703B2
(en)
|
2018-04-04 |
2022-09-27 |
Bicycletx Limited |
Heterotandem bicyclic peptide complexes
|
|
CA3099308A1
(en)
|
2018-05-21 |
2019-11-28 |
Compass Therapeutics Llc |
Compositions and methods for enhancing the killing of target cells by nk cells
|
|
GB201810316D0
(en)
|
2018-06-22 |
2018-08-08 |
Bicyclerd Ltd |
Peptide ligands for binding to EphA2
|
|
GB201810325D0
(en)
|
2018-06-22 |
2018-08-08 |
Bicycletx Ltd |
Peptide ligands for binding to PSMA
|
|
US11180531B2
(en)
|
2018-06-22 |
2021-11-23 |
Bicycletx Limited |
Bicyclic peptide ligands specific for Nectin-4
|
|
US10919937B2
(en)
|
2018-10-23 |
2021-02-16 |
Bicycletx Limited |
Bicyclic peptide ligands and uses thereof
|
|
CN113507962A
(zh)
|
2018-12-13 |
2021-10-15 |
拜斯科技术开发有限公司 |
Mt1-mmp特异性的双环肽配体
|
|
GB201820325D0
(en)
|
2018-12-13 |
2019-01-30 |
Bicyclerd Ltd |
Bicyclic peptide ligands specific for psma
|
|
CA3120800A1
(en)
|
2018-12-17 |
2020-06-25 |
Revitope Limited |
Twin immune cell engager
|
|
JP2022514687A
(ja)
|
2018-12-21 |
2022-02-14 |
バイスクルアールディー・リミテッド |
Ｐｄ－ｌ１に特異的な二環式ペプチドリガンド
|
|
US20220306689A9
(en)
|
2018-12-21 |
2022-09-29 |
Bicycletx Limited |
Bicyclic peptide ligands specific for pd-l1
|
|
SG11202110828UA
(en)
|
2019-04-02 |
2021-10-28 |
Bicycletx Ltd |
Bicycle toxin conjugates and uses thereof
|
|
KR20220007098A
(ko)
|
2019-05-09 |
2022-01-18 |
바이사이클티엑스 리미티드 |
Ox40에 특이적인 이환식 펩티드 리간드
|
|
TW202110485A
(zh)
|
2019-07-30 |
2021-03-16 |
英商拜西可泰克斯有限公司 |
異質雙環肽複合物
|
|
JP2022544246A
(ja)
|
2019-08-13 |
2022-10-17 |
バイスクルテクス・リミテッド |
修飾された多量体二環式ペプチドリガンド
|
|
US11332500B2
(en)
|
2019-10-03 |
2022-05-17 |
Bicycletx Limited |
Heterotandem bicyclic peptide complexes
|
|
IL293200A
(en)
|
2019-11-27 |
2022-07-01 |
Bicycletx Ltd |
Bicyclic peptide ligands specific for epha2 and their use
|
|
CN115698720A
(zh)
|
2020-06-12 |
2023-02-03 |
拜斯科技术开发有限公司 |
特征在于促红细胞生成素产生肝细胞受体a2(epha2)的过表达的疾病的治疗
|
|
CA3186504A1
(en)
|
2020-08-17 |
2022-02-24 |
Stephen J. Blakemore |
Bicycle conjugates specific for nectin-4 and uses thereof
|
|
EP4274844A1
(en)
|
2021-01-08 |
2023-11-15 |
BicycleTx Limited |
Heterotandem bicyclic peptide complexes
|
|
JP2024502189A
(ja)
|
2021-01-11 |
2024-01-17 |
バイシクルティーエクス・リミテッド |
癌を処置する方法
|