JPWO2020180897A5 - - Google Patents
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- Publication number
- JPWO2020180897A5 JPWO2020180897A5 JP2021552130A JP2021552130A JPWO2020180897A5 JP WO2020180897 A5 JPWO2020180897 A5 JP WO2020180897A5 JP 2021552130 A JP2021552130 A JP 2021552130A JP 2021552130 A JP2021552130 A JP 2021552130A JP WO2020180897 A5 JPWO2020180897 A5 JP WO2020180897A5
- Authority
- JP
- Japan
- Prior art keywords
- oligonucleotide
- multimer
- subunits
- present
- subunit
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962813599P | 2019-03-04 | 2019-03-04 | |
| US62/813,599 | 2019-03-04 | ||
| US201962824771P | 2019-03-27 | 2019-03-27 | |
| US62/824,771 | 2019-03-27 | ||
| PCT/US2020/020845 WO2020180897A1 (en) | 2019-03-04 | 2020-03-03 | Multimeric oligonucleotides with enhanced bioactivity |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022523226A JP2022523226A (ja) | 2022-04-21 |
| JPWO2020180897A5 true JPWO2020180897A5 (https=) | 2023-02-15 |
| JP2022523226A5 JP2022523226A5 (https=) | 2023-02-15 |
Family
ID=72337000
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021552130A Pending JP2022523226A (ja) | 2019-03-04 | 2020-03-03 | 増強された生理活性を有する多量体オリゴヌクレオチド |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20230287406A1 (https=) |
| EP (1) | EP3935168A4 (https=) |
| JP (1) | JP2022523226A (https=) |
| CN (1) | CN113994004A (https=) |
| AU (1) | AU2020233375A1 (https=) |
| CA (1) | CA3132505A1 (https=) |
| IL (1) | IL286070A (https=) |
| WO (1) | WO2020180897A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3576752A4 (en) | 2017-02-06 | 2020-12-16 | Mpeg La, LLC | MULTIMERIC OLIGONUCLEOTIDES WITH REDUCED RENAL CLEARANCE |
| AU2021263932B2 (en) * | 2020-04-30 | 2025-07-03 | Mpeg La, L.L.C. | Multimeric oligonucleotides with divided strands |
| US20240318174A1 (en) * | 2021-02-08 | 2024-09-26 | Ractigen Therapeutics | Multi-Valent Oligonucleotide Agent and Methods of Use Thereof |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE356630T1 (de) * | 1998-04-03 | 2007-04-15 | Univ Iowa Res Found | Verfahren und produkte zur stimulierung des immunsystems mittels immunotherapeutischer oligonukleotide und zytokine |
| US8748405B2 (en) * | 2007-01-26 | 2014-06-10 | City Of Hope | Methods and compositions for the treatment of cancer or other diseases |
| US20080311040A1 (en) * | 2007-03-06 | 2008-12-18 | Flagship Ventures | METHODS AND COMPOSITIONS FOR IMPROVED THERAPEUTIC EFFECTS WITH siRNA |
| KR101141544B1 (ko) * | 2009-03-13 | 2012-05-03 | 한국과학기술원 | 에스아이알엔에이 다중 접합체 및 이의 제조방법 |
| HK1200484A1 (zh) * | 2011-09-14 | 2015-08-07 | Translate Bio Ma, Inc. | 多聚寡核苷酸化合物 |
| US9956294B2 (en) * | 2013-01-18 | 2018-05-01 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Targeted sensitization of non-del(5q) malignant cells |
| IL316159A (en) * | 2015-06-15 | 2024-12-01 | Mpeg La Llc | Defined Oligonucleotide Multimers and Methods for Manufacture Thereof |
| JP7073109B2 (ja) * | 2015-07-02 | 2022-05-23 | シティ・オブ・ホープ | ホスホロチオエート化オリゴデオキシヌクレオチドを含む化合物及び組成物、ならびにそれらの使用法 |
| EP3368671A1 (en) * | 2015-10-26 | 2018-09-05 | Translate Bio Ma, Inc. | Methods and compositions for increasing smn expression |
| WO2018030338A1 (ja) * | 2016-08-08 | 2018-02-15 | 浩文 山本 | アジュバント組成物 |
| EP3576752A4 (en) * | 2017-02-06 | 2020-12-16 | Mpeg La, LLC | MULTIMERIC OLIGONUCLEOTIDES WITH REDUCED RENAL CLEARANCE |
| JP2020522265A (ja) * | 2017-06-02 | 2020-07-30 | ウェイブ ライフ サイエンシズ リミテッドＷａｖｅ Ｌｉｆｅ Ｓｃｉｅｎｃｅｓ Ｌｔｄ． | オリゴヌクレオチド組成物及びその使用方法 |
-
2020
- 2020-03-03 CA CA3132505A patent/CA3132505A1/en active Pending
- 2020-03-03 WO PCT/US2020/020845 patent/WO2020180897A1/en not_active Ceased
- 2020-03-03 EP EP20766332.9A patent/EP3935168A4/en active Pending
- 2020-03-03 JP JP2021552130A patent/JP2022523226A/ja active Pending
- 2020-03-03 AU AU2020233375A patent/AU2020233375A1/en active Pending
- 2020-03-03 US US17/436,254 patent/US20230287406A1/en not_active Abandoned
- 2020-03-03 CN CN202080033528.2A patent/CN113994004A/zh active Pending
-
2021
- 2021-09-02 IL IL286070A patent/IL286070A/en unknown
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