JP2022523226A5 - - Google Patents

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Publication number
JP2022523226A5
JP2022523226A5 JP2021552130A JP2021552130A JP2022523226A5 JP 2022523226 A5 JP2022523226 A5 JP 2022523226A5 JP 2021552130 A JP2021552130 A JP 2021552130A JP 2021552130 A JP2021552130 A JP 2021552130A JP 2022523226 A5 JP2022523226 A5 JP 2022523226A5
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JP
Japan
Application number
JP2021552130A
Other languages
Japanese (ja)
Other versions
JPWO2020180897A5 (https=
JP2022523226A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/020845 external-priority patent/WO2020180897A1/en
Publication of JP2022523226A publication Critical patent/JP2022523226A/ja
Publication of JPWO2020180897A5 publication Critical patent/JPWO2020180897A5/ja
Publication of JP2022523226A5 publication Critical patent/JP2022523226A5/ja
Pending legal-status Critical Current

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JP2021552130A 2019-03-04 2020-03-03 増強された生理活性を有する多量体オリゴヌクレオチド Pending JP2022523226A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962813599P 2019-03-04 2019-03-04
US62/813,599 2019-03-04
US201962824771P 2019-03-27 2019-03-27
US62/824,771 2019-03-27
PCT/US2020/020845 WO2020180897A1 (en) 2019-03-04 2020-03-03 Multimeric oligonucleotides with enhanced bioactivity

Publications (3)

Publication Number Publication Date
JP2022523226A JP2022523226A (ja) 2022-04-21
JPWO2020180897A5 JPWO2020180897A5 (https=) 2023-02-15
JP2022523226A5 true JP2022523226A5 (https=) 2023-02-15

Family

ID=72337000

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021552130A Pending JP2022523226A (ja) 2019-03-04 2020-03-03 増強された生理活性を有する多量体オリゴヌクレオチド

Country Status (8)

Country Link
US (1) US20230287406A1 (https=)
EP (1) EP3935168A4 (https=)
JP (1) JP2022523226A (https=)
CN (1) CN113994004A (https=)
AU (1) AU2020233375A1 (https=)
CA (1) CA3132505A1 (https=)
IL (1) IL286070A (https=)
WO (1) WO2020180897A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3576752A4 (en) 2017-02-06 2020-12-16 Mpeg La, LLC MULTIMERIC OLIGONUCLEOTIDES WITH REDUCED RENAL CLEARANCE
AU2021263932B2 (en) * 2020-04-30 2025-07-03 Mpeg La, L.L.C. Multimeric oligonucleotides with divided strands
US20240318174A1 (en) * 2021-02-08 2024-09-26 Ractigen Therapeutics Multi-Valent Oligonucleotide Agent and Methods of Use Thereof

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE356630T1 (de) * 1998-04-03 2007-04-15 Univ Iowa Res Found Verfahren und produkte zur stimulierung des immunsystems mittels immunotherapeutischer oligonukleotide und zytokine
US8748405B2 (en) * 2007-01-26 2014-06-10 City Of Hope Methods and compositions for the treatment of cancer or other diseases
US20080311040A1 (en) * 2007-03-06 2008-12-18 Flagship Ventures METHODS AND COMPOSITIONS FOR IMPROVED THERAPEUTIC EFFECTS WITH siRNA
KR101141544B1 (ko) * 2009-03-13 2012-05-03 한국과학기술원 에스아이알엔에이 다중 접합체 및 이의 제조방법
HK1200484A1 (zh) * 2011-09-14 2015-08-07 Translate Bio Ma, Inc. 多聚寡核苷酸化合物
US9956294B2 (en) * 2013-01-18 2018-05-01 H. Lee Moffitt Cancer Center And Research Institute, Inc. Targeted sensitization of non-del(5q) malignant cells
IL316159A (en) * 2015-06-15 2024-12-01 Mpeg La Llc Defined Oligonucleotide Multimers and Methods for Manufacture Thereof
JP7073109B2 (ja) * 2015-07-02 2022-05-23 シティ・オブ・ホープ ホスホロチオエート化オリゴデオキシヌクレオチドを含む化合物及び組成物、ならびにそれらの使用法
EP3368671A1 (en) * 2015-10-26 2018-09-05 Translate Bio Ma, Inc. Methods and compositions for increasing smn expression
WO2018030338A1 (ja) * 2016-08-08 2018-02-15 浩文 山本 アジュバント組成物
EP3576752A4 (en) * 2017-02-06 2020-12-16 Mpeg La, LLC MULTIMERIC OLIGONUCLEOTIDES WITH REDUCED RENAL CLEARANCE
JP2020522265A (ja) * 2017-06-02 2020-07-30 ウェイブ ライフ サイエンシズ リミテッドWave Life Sciences Ltd. オリゴヌクレオチド組成物及びその使用方法

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