JPWO2023283546A5 - - Google Patents
Download PDFInfo
- Publication number
- JPWO2023283546A5 JPWO2023283546A5 JP2024500649A JP2024500649A JPWO2023283546A5 JP WO2023283546 A5 JPWO2023283546 A5 JP WO2023283546A5 JP 2024500649 A JP2024500649 A JP 2024500649A JP 2024500649 A JP2024500649 A JP 2024500649A JP WO2023283546 A5 JPWO2023283546 A5 JP WO2023283546A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- acid strand
- strand
- acid complex
- central region
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163218833P | 2021-07-06 | 2021-07-06 | |
| US63/218,833 | 2021-07-06 | ||
| PCT/US2022/073426 WO2023283546A1 (en) | 2021-07-06 | 2022-07-05 | Conditionally activatable nucleic acid complexes |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2024525646A JP2024525646A (ja) | 2024-07-12 |
| JP2024525646A5 JP2024525646A5 (https=) | 2025-07-14 |
| JPWO2023283546A5 true JPWO2023283546A5 (https=) | 2025-07-14 |
Family
ID=84802039
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024500649A Pending JP2024525646A (ja) | 2021-07-06 | 2022-07-05 | 条件付きで活性化可能な核酸複合体 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20250188453A1 (https=) |
| EP (1) | EP4367126A4 (https=) |
| JP (1) | JP2024525646A (https=) |
| KR (1) | KR20240095154A (https=) |
| CN (1) | CN118202048A (https=) |
| AU (1) | AU2022308051A1 (https=) |
| CA (1) | CA3224942A1 (https=) |
| IL (1) | IL309942A (https=) |
| WO (1) | WO2023283546A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019014656A1 (en) | 2017-07-14 | 2019-01-17 | Han Si Ping | METALLIC OLIGONUCLEOTIDE JONCTIONS FOR THE ADMINISTRATION OF THERAPEUTIC AGENTS |
| EP3665281A4 (en) | 2017-08-10 | 2021-05-05 | City of Hope | CONDITIONAL SIRNA AND ITS USE IN THE TREATMENT OF CARDIAC HYERTROPHY |
| CN113166750B (zh) | 2018-08-10 | 2025-02-18 | 希望之城 | 可编程的条件性sirna及其用途 |
| WO2026006174A1 (en) * | 2024-06-24 | 2026-01-02 | Arizona Board Of Regents On Behalf Of Arizona State University | Compositions and methods related to removal of transmembrane sensors |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8710199B2 (en) * | 2010-06-23 | 2014-04-29 | California Institute Of Technology | Signal activated molecular delivery |
| US9725715B2 (en) * | 2011-06-23 | 2017-08-08 | California Institute Of Technology | Signal activatable constructs and related components compositions methods and systems |
| WO2013142735A1 (en) * | 2012-03-21 | 2013-09-26 | California Institute Of Technology | Targeting domain and related signal activated molecular delivery |
| WO2019014656A1 (en) * | 2017-07-14 | 2019-01-17 | Han Si Ping | METALLIC OLIGONUCLEOTIDE JONCTIONS FOR THE ADMINISTRATION OF THERAPEUTIC AGENTS |
| WO2019033083A1 (en) * | 2017-08-10 | 2019-02-14 | City Of Hope | CONDITIONAL RNAIDS AND THEIR USES IN THE TREATMENT OF ACUTE MYELOID LEUKEMIA |
| EP3665281A4 (en) * | 2017-08-10 | 2021-05-05 | City of Hope | CONDITIONAL SIRNA AND ITS USE IN THE TREATMENT OF CARDIAC HYERTROPHY |
| CN113166750B (zh) * | 2018-08-10 | 2025-02-18 | 希望之城 | 可编程的条件性sirna及其用途 |
| US11834659B2 (en) * | 2019-09-26 | 2023-12-05 | Massachusetts Institute Of Technology | Trans-activated functional RNA by strand displacement and uses thereof |
-
2022
- 2022-07-05 EP EP22838543.1A patent/EP4367126A4/en active Pending
- 2022-07-05 KR KR1020247004151A patent/KR20240095154A/ko active Pending
- 2022-07-05 WO PCT/US2022/073426 patent/WO2023283546A1/en not_active Ceased
- 2022-07-05 IL IL309942A patent/IL309942A/en unknown
- 2022-07-05 US US18/575,443 patent/US20250188453A1/en active Pending
- 2022-07-05 JP JP2024500649A patent/JP2024525646A/ja active Pending
- 2022-07-05 CN CN202280060503.0A patent/CN118202048A/zh active Pending
- 2022-07-05 AU AU2022308051A patent/AU2022308051A1/en active Pending
- 2022-07-05 CA CA3224942A patent/CA3224942A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP7406793B2 (ja) | ２テイル自己デリバリー型ｓｉＲＮＡおよび関連方法 | |
| CN113748208A (zh) | 用于抑制中枢神经系统中的基因表达的组合物和方法 | |
| TW202024324A (zh) | 用於抑制17β-HSD第13型(HSD17B13)表現之RNAi藥劑、其組合物及使用方法 | |
| TW201922264A (zh) | 用於抑制類血管生成素蛋白-3(ANGPTL3)表現的RNAi藥劑及組合物及使用方法 | |
| US20060105975A1 (en) | Aptamer-mediated intracellular delivery of therapeutic oligonucleotides | |
| JP2018516091A5 (https=) | ||
| AU2021337595A1 (en) | DUX4 inhibitors and methods of use thereof | |
| KR20220069103A (ko) | 최소 플루오린 함량을 갖는 작은 간섭 rna의 화학적 변형 | |
| CN113286887A (zh) | 用于肌营养不良蛋白外显子跳跃的双特异性反义低聚核苷酸 | |
| JPWO2020190768A5 (https=) | ||
| KR20260007576A (ko) | 변형된 가이드 rna | |
| JPWO2020205605A5 (https=) | ||
| WO2025113592A1 (zh) | 一种抑制补体系统基因表达的rna抑制剂及其应用 | |
| CN112055598A (zh) | 用于抑制gys2表达的组合物和方法 | |
| JPWO2023283546A5 (https=) | ||
| JPWO2021119226A5 (https=) | ||
| JPWO2023283550A5 (https=) | ||
| JP2025542580A (ja) | 遺伝子サイレンシング技術としての、デオキシリボヌクレオチドが散在している短鎖二重鎖ｒｎａ、およびその使用 | |
| AU2019228448A1 (en) | Methods and compositions for treating bile duct paucity-associated conditions | |
| TW202309286A (zh) | 作為新穎基因靜默技術的非對稱短雙股ｄｎａ及其應用 | |
| JP2024520556A (ja) | 新規遺伝子サイレンシング技術としての短鎖二重鎖ｄｎａおよびその使用 | |
| WO2023168202A2 (en) | Certain dux4 inhibitors and methods of use thereof | |
| JP7208911B2 (ja) | 核酸分子発現の調節 | |
| TW202516004A (zh) | 調節ｊａｋ１表現之雙股寡核苷酸 | |
| WO2018014848A1 (zh) | 一种小rna抑制剂 |