JPWO2020168291A5 - - Google Patents
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- Publication number
- JPWO2020168291A5 JPWO2020168291A5 JP2021547336A JP2021547336A JPWO2020168291A5 JP WO2020168291 A5 JPWO2020168291 A5 JP WO2020168291A5 JP 2021547336 A JP2021547336 A JP 2021547336A JP 2021547336 A JP2021547336 A JP 2021547336A JP WO2020168291 A5 JPWO2020168291 A5 JP WO2020168291A5
- Authority
- JP
- Japan
- Prior art keywords
- ribonucleic acid
- sequence
- engineered
- engineered nuclease
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023146414A JP7502537B2 (ja) | 2019-02-14 | 2023-09-08 | Ｒｕｖｃドメインを有する酵素 |
| JP2024091759A JP2024133476A (ja) | 2019-02-14 | 2024-06-05 | Ｒｕｖｃドメインを有する酵素 |
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962805868P | 2019-02-14 | 2019-02-14 | |
| US201962805878P | 2019-02-14 | 2019-02-14 | |
| US201962805899P | 2019-02-14 | 2019-02-14 | |
| US62/805,878 | 2019-02-14 | ||
| US62/805,868 | 2019-02-14 | ||
| US62/805,899 | 2019-02-14 | ||
| US201962874414P | 2019-07-15 | 2019-07-15 | |
| US62/874,414 | 2019-07-15 | ||
| PCT/US2020/018432 WO2020168291A1 (en) | 2019-02-14 | 2020-02-14 | Enzymes with ruvc domains |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023146414A Division JP7502537B2 (ja) | 2019-02-14 | 2023-09-08 | Ｒｕｖｃドメインを有する酵素 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022520428A JP2022520428A (ja) | 2022-03-30 |
| JPWO2020168291A5 true JPWO2020168291A5 (https=) | 2023-02-21 |
| JP2022520428A5 JP2022520428A5 (https=) | 2023-02-21 |
Family
ID=72045639
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021547336A Ceased JP2022520428A (ja) | 2019-02-14 | 2020-02-14 | Ｒｕｖｃドメインを有する酵素 |
| JP2023146414A Active JP7502537B2 (ja) | 2019-02-14 | 2023-09-08 | Ｒｕｖｃドメインを有する酵素 |
| JP2024091759A Pending JP2024133476A (ja) | 2019-02-14 | 2024-06-05 | Ｒｕｖｃドメインを有する酵素 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023146414A Active JP7502537B2 (ja) | 2019-02-14 | 2023-09-08 | Ｒｕｖｃドメインを有する酵素 |
| JP2024091759A Pending JP2024133476A (ja) | 2019-02-14 | 2024-06-05 | Ｒｕｖｃドメインを有する酵素 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20240117330A1 (https=) |
| EP (1) | EP3924482A4 (https=) |
| JP (3) | JP2022520428A (https=) |
| KR (2) | KR102623312B1 (https=) |
| CN (2) | CN113728098A (https=) |
| AU (3) | AU2020223370B2 (https=) |
| CA (2) | CA3130135C (https=) |
| MX (2) | MX2021009886A (https=) |
| WO (1) | WO2020168291A1 (https=) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3204496A1 (en) | 2014-10-10 | 2017-08-16 | Editas Medicine, Inc. | Compositions and methods for promoting homology directed repair |
| EP3823633A4 (en) | 2018-06-29 | 2023-05-03 | Editas Medicine, Inc. | SYNTHETIC LEAD MOLECULES, COMPOSITIONS AND METHODS RELATED THERETO |
| US10913941B2 (en) | 2019-02-14 | 2021-02-09 | Metagenomi Ip Technologies, Llc | Enzymes with RuvC domains |
| AU2020223370B2 (en) * | 2019-02-14 | 2023-04-20 | Metagenomi Therapeutics, Inc. | Enzymes with RuvC domains |
| GB2594339B (en) * | 2020-02-14 | 2023-02-08 | Metagenomi Inc | Enzymes with RUVC domains |
| GB2617658B (en) | 2020-03-06 | 2024-04-17 | Metagenomi Inc | Class II, type V CRISPR systems |
| GB2608292B (en) * | 2020-03-31 | 2024-02-14 | Metagenomi Inc | Class II, type II CRISPR systems |
| EP4165177A4 (en) * | 2020-05-08 | 2024-08-28 | Metagenomi, Inc. | ENZYMES WITH RUVC DOMAINS |
| KR20230021657A (ko) * | 2020-05-08 | 2023-02-14 | 메타지노미, 인크. | Ruvc 도메인을 포함하는 효소 |
| CA3192224A1 (en) | 2020-09-11 | 2022-03-17 | Jyun-Liang LIN | Base editing enzymes |
| GB2700205B (en) * | 2020-09-11 | 2026-04-15 | Metagenomi Therapeutics Inc | Base editing enzymes |
| US20230383273A1 (en) * | 2020-10-21 | 2023-11-30 | Emendobio Inc. | Novel omni 56, 58, 65, 68, 71, 75, 78, and 84 crispr nucleases |
| WO2022098681A2 (en) * | 2020-11-03 | 2022-05-12 | Caspr Biotech Corporation | Novel class 2 crispr-cas rna-guided endonucleases |
| WO2022159742A1 (en) * | 2021-01-22 | 2022-07-28 | Metagenomi, Inc | Novel engineered and chimeric nucleases |
| BR112023014719A2 (pt) * | 2021-01-22 | 2023-12-05 | Metagenomi Inc | Novas nucleases quiméricas e manipuladas |
| BR112023018948A2 (pt) * | 2021-03-19 | 2023-10-17 | Metagenomi Inc | Edição multiplex com enzimas cas |
| WO2022232638A2 (en) * | 2021-04-30 | 2022-11-03 | Metagenomi, Inc. | Enzymes with ruvc domains |
| CA3225082A1 (en) * | 2021-08-27 | 2023-03-02 | Brian C. Thomas | Enzymes with ruvc domains |
| AU2022380842A1 (en) | 2021-11-05 | 2024-05-23 | Metagenomi Therapeutics, Inc. | Base editing enzymes |
| MX2024006257A (es) | 2021-11-24 | 2024-07-29 | Metagenomi Inc | Sistemas de endonucleasas. |
| WO2023122663A2 (en) * | 2021-12-23 | 2023-06-29 | Mammoth Biosciences, Inc. | Effector proteins and methods of use |
| WO2023194359A1 (en) * | 2022-04-04 | 2023-10-12 | Alia Therapeutics Srl | Compositions and methods for treatment of usher syndrome type 2a |
| CN119923466A (zh) * | 2022-06-15 | 2025-05-02 | 比姆医疗股份有限公司 | 用于减少补体激活的组合物和方法 |
| US20260014279A1 (en) * | 2022-09-16 | 2026-01-15 | Alia Therapeutics Srl | Enqp type cas proteins and applications thereof |
| KR20250153814A (ko) * | 2023-03-01 | 2025-10-27 | 메타지노미, 인크. | Ruvc 도메인을 갖는 효소 |
| WO2025106934A1 (en) * | 2023-11-16 | 2025-05-22 | Metagenomi, Inc. | Enzymes with ruvc domains |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2894684A1 (en) * | 2012-12-12 | 2014-06-19 | The Broad Institute, Inc. | Engineering and optimization of improved crispr-cas systems, methods and enzyme compositions for sequence manipulation in eukaryotes |
| EP3303634B1 (en) * | 2015-06-03 | 2023-08-30 | The Regents of The University of California | Cas9 variants and methods of use thereof |
| WO2016205759A1 (en) * | 2015-06-18 | 2016-12-22 | The Broad Institute Inc. | Engineering and optimization of systems, methods, enzymes and guide scaffolds of cas9 orthologs and variants for sequence manipulation |
| US12431216B2 (en) * | 2016-08-17 | 2025-09-30 | Broad Institute, Inc. | Methods for identifying class 2 crispr-cas systems |
| KR20200124702A (ko) * | 2018-02-23 | 2020-11-03 | 파이어니어 하이 부렛드 인터내쇼날 인코포레이팃드 | 신규한 cas9 오르소로그 |
| AU2020223370B2 (en) | 2019-02-14 | 2023-04-20 | Metagenomi Therapeutics, Inc. | Enzymes with RuvC domains |
-
2020
- 2020-02-14 AU AU2020223370A patent/AU2020223370B2/en active Active
- 2020-02-14 WO PCT/US2020/018432 patent/WO2020168291A1/en not_active Ceased
- 2020-02-14 CN CN202080028787.6A patent/CN113728098A/zh active Pending
- 2020-02-14 KR KR1020217028874A patent/KR102623312B1/ko active Active
- 2020-02-14 CA CA3130135A patent/CA3130135C/en active Active
- 2020-02-14 JP JP2021547336A patent/JP2022520428A/ja not_active Ceased
- 2020-02-14 EP EP20756259.6A patent/EP3924482A4/en active Pending
- 2020-02-14 CA CA3241703A patent/CA3241703C/en active Active
- 2020-02-14 MX MX2021009886A patent/MX2021009886A/es unknown
- 2020-02-14 KR KR1020247000311A patent/KR20240007322A/ko active Pending
- 2020-02-14 CN CN202310441977.6A patent/CN116515797A/zh active Pending
-
2021
- 2021-08-16 MX MX2023006575A patent/MX2023006575A/es unknown
-
2023
- 2023-06-15 US US18/335,481 patent/US20240117330A1/en active Pending
- 2023-07-17 AU AU2023206079A patent/AU2023206079A1/en not_active Abandoned
- 2023-09-08 JP JP2023146414A patent/JP7502537B2/ja active Active
-
2024
- 2024-06-05 JP JP2024091759A patent/JP2024133476A/ja active Pending
-
2025
- 2025-12-11 AU AU2025279720A patent/AU2025279720A1/en active Pending
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