|
US4271164A
(en)
|
1979-04-16 |
1981-06-02 |
Warner-Lambert Company |
6-Substituted-arylpyrido[2,3-d]pyrimidin-7-amines and derivatives
|
|
GB9420168D0
(en)
|
1994-10-06 |
1994-11-23 |
Boots Co Plc |
Therapeutic agents
|
|
CA2290509A1
(en)
|
1997-07-01 |
1999-01-14 |
Warner-Lambert Company |
2-(4-bromo or 4-iodo phenylamino) benzoic acid derivatives and their use as mek inhibitors
|
|
NZ501276A
(en)
|
1997-07-01 |
2000-10-27 |
Warner Lambert Co |
4-bromo or 4-iodo phenylamino benzhydroxamic acid derivatives and their use as MEK inhibitors in treating proliferative disorders
|
|
JP2910748B2
(ja)
|
1997-11-12 |
1999-06-23 |
日本電気株式会社 |
異質同軸部材の端面の球状加工装置及びその方法
|
|
HUP0105092A3
(en)
|
1999-01-13 |
2003-12-29 |
Warner Lambert Co |
1-heterocycle substituted diarylamines and medicaments containing them
|
|
SG2013013339A
(en)
|
2002-03-13 |
2014-12-30 |
Array Biopharma Inc |
N3 alkylated benzimidazole derivatives as mek inhibitors
|
|
US20050202001A1
(en)
|
2002-04-24 |
2005-09-15 |
Han-Mo Koo |
Enhancement of human epidermal melanogenesis
|
|
CA2492112A1
(en)
|
2002-08-06 |
2004-02-19 |
F. Hoffmann-La Roche Ag |
6-alkoxy-pyrido-pyrimidines as p-38 map kinase inhibitors
|
|
CA2546353A1
(en)
|
2003-11-19 |
2005-06-09 |
Array Biopharma Inc. |
Bicyclic inhibitors of mek and methods of use thereof
|
|
WO2006078287A2
(en)
*
|
2004-05-06 |
2006-07-27 |
Plexxikon, Inc. |
Pde4b inhibitors and uses therefor
|
|
AU2005252110B2
(en)
|
2004-06-11 |
2008-09-04 |
Shionogi & Co., Ltd. |
5-amino-2,4,7-trioxo-3,4,7,8-tetrahydro-2H-pyrido[2,3-D] pyrimidine derivatives and related compounds for the treatment of cancer
|
|
US7674907B2
(en)
|
2004-07-23 |
2010-03-09 |
Amgen Inc. |
Furanopyridine derivatives and methods of use
|
|
MX2007004781A
(es)
|
2004-10-20 |
2007-05-11 |
Applied Research Systems |
Derivados de 3-arilamino piridina.
|
|
CN102206216B
(zh)
|
2005-06-22 |
2014-11-12 |
普莱希科公司 |
作为蛋白质激酶抑制剂的吡咯并[2,3-b]吡啶衍生物
|
|
HRP20110498T1
(hr)
|
2005-10-07 |
2011-08-31 |
Exelixis |
Azetidini kao inhibitori mek za liječenje proliferativnih bolesti
|
|
GB0601962D0
(en)
|
2006-01-31 |
2006-03-15 |
Ucb Sa |
Therapeutic agents
|
|
US7772233B2
(en)
|
2006-04-19 |
2010-08-10 |
Merck Serono, S.A. |
Arylamino N-heteroaryl compounds as MEK inhibitors
|
|
GB0616214D0
(en)
*
|
2006-08-15 |
2006-09-27 |
Ucb Sa |
Therapeutic Agents
|
|
CN101528231A
(zh)
*
|
2006-08-16 |
2009-09-09 |
埃克塞利希斯股份有限公司 |
在癌症的治疗中使用pi3k和mek调控剂
|
|
ES2528797T3
(es)
|
2006-08-21 |
2015-02-12 |
Genentech, Inc. |
Compuestos de aza-benzotiofenilo y métodos de uso
|
|
ES2376771T3
(es)
|
2006-08-21 |
2012-03-16 |
Genentech, Inc. |
Compuestos aza-benzofuranilo y métodos de utilización
|
|
RU2463038C2
(ru)
|
2006-10-17 |
2012-10-10 |
Нуво Рисерч Инк. |
Диклофенаковый гель
|
|
EP2089359A2
(en)
|
2006-10-31 |
2009-08-19 |
Takeda Pharmaceutical Company Limited |
Mapk/erk kinase inhibitors
|
|
EP2099796B1
(en)
|
2006-11-30 |
2011-06-01 |
Genentech, Inc. |
Aza-indolyl compounds and methods of use
|
|
CL2008001373A1
(es)
|
2007-05-11 |
2008-11-21 |
Bayer Schering Pharma Ag |
Compuestos derivados de fenilamino-benceno sustituidos; metodo de preparacion; composicion farmaceutica; kit farmceuticos; y uso de dichos compuestos en el tratamiento del cancer.
|
|
WO2008148034A1
(en)
*
|
2007-05-25 |
2008-12-04 |
Takeda Pharmaceutical Company Limited |
Mapk/erk kinase inhibitors
|
|
GB0714384D0
(en)
|
2007-07-23 |
2007-09-05 |
Ucb Pharma Sa |
theraputic agents
|
|
NZ586575A
(en)
|
2007-12-21 |
2012-03-30 |
Genentech Inc |
Azaindolizines and methods of use
|
|
GB0801080D0
(en)
|
2008-01-21 |
2008-02-27 |
Ucb Pharma Sa |
Therapeutic agents
|
|
GB0801081D0
(en)
|
2008-01-21 |
2008-02-27 |
Ucb Pharma Sa |
Therapeutic agents
|
|
WO2009093008A1
(en)
|
2008-01-21 |
2009-07-30 |
Ucb Pharma S.A. |
Thieno-pyridine derivatives as mek inhibitors
|
|
GB0811304D0
(en)
|
2008-06-19 |
2008-07-30 |
Ucb Pharma Sa |
Therapeutic agents
|
|
EP2440204B1
(en)
|
2009-06-12 |
2013-12-18 |
Bristol-Myers Squibb Company |
Nicotinamide compounds useful as kinase modulators
|
|
DE102010012594A1
(de)
|
2010-03-23 |
2011-09-29 |
Beiersdorf Ag |
Kosmetische oder dermatologische Zubereitungen mit einem Gehalt an einem oder mehreren Thiazolderivaten
|
|
WO2012040636A2
(en)
|
2010-09-24 |
2012-03-29 |
The Broad Institute, Inc. |
Compounds and methods for treating diseases mediated by protease activated receptors
|
|
MX341471B
(es)
|
2010-11-05 |
2016-08-22 |
Hoffmann La Roche |
Uso de compuestos farmaceuticos activos para el tratamiento de estados patologicos del sistema nervioso central.
|
|
WO2012099968A1
(en)
|
2011-01-19 |
2012-07-26 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for treating skin cancer associated diseases
|
|
GB201104267D0
(en)
|
2011-03-14 |
2011-04-27 |
Cancer Rec Tech Ltd |
Pyrrolopyridineamino derivatives
|
|
JP5931187B2
(ja)
|
2011-06-17 |
2016-06-08 |
シェンヤン・シノケム・アグロケミカルズ・アールアンドディー・カンパニーリミテッドＳｈｅｎｙａｎｇ Ｓｉｎｏｃｈｅｍ Ａｇｒｏｃｈｅｍｉｃａｌｓ Ｒ＆Ｄ Ｃｏ．， Ｌｔｄ． |
置換シアノアニリン化合物、その調製法及び使用
|
|
WO2014179785A1
(en)
|
2013-05-03 |
2014-11-06 |
Inscent, Inc. |
Improved honeybee repellents and uses thereof
|
|
US10835513B2
(en)
|
2013-06-28 |
2020-11-17 |
The Regents Of The University Of California |
Methods and treatments for the learning and memory deficits associated with Noonan syndrome
|
|
US9572828B2
(en)
|
2013-07-18 |
2017-02-21 |
The Board Of Regents Of The University Of Texas System |
Treatment for melanoma
|
|
CN105384754B
(zh)
|
2014-09-02 |
2018-04-20 |
上海科州药物研发有限公司 |
作为蛋白激酶抑制剂的杂环类化合物及其制备方法和用途
|
|
EP3383912A4
(en)
|
2015-11-30 |
2019-11-06 |
Ignyta, Inc. |
TOPICAL FORMULATIONS
|
|
EP3301094A1
(en)
|
2016-09-30 |
2018-04-04 |
Mutabilis |
Heterocyclic compounds and their use in preventing or treating bacterial infections
|
|
US11161845B2
(en)
|
2017-05-19 |
2021-11-02 |
Nflection Therapeutics, Inc. |
Pyrrolopyridine-aniline compounds for treatment of dermal disorders
|
|
MX2019013562A
(es)
|
2017-05-19 |
2020-08-03 |
Nflection Therapeutics Inc |
Compuestos de anilina heteroaromatica o fusionados para el tratamiento de trastornos dermicos.
|
|
WO2019139970A1
(en)
|
2018-01-09 |
2019-07-18 |
Duke University |
Topical administration of mek inhibiting agents for the treatment of skin disorders
|
|
EP3873528A4
(en)
|
2018-10-29 |
2022-08-10 |
The Johns Hopkins University |
Rasopathy treatment
|
|
MA55143A
(fr)
|
2018-11-20 |
2021-09-29 |
H Lee Moffitt Cancer Center & Res Institute Inc |
Composés aryl-aniline et hétéroaryl-aniline pour le traitement de cancers de la peau
|
|
US12466818B2
(en)
|
2018-11-20 |
2025-11-11 |
Nflection Therapeutics, Inc. |
Thienyl-aniline compounds for treatment of dermal disorders
|
|
WO2020106304A1
(en)
|
2018-11-20 |
2020-05-28 |
Nflection Therapeutics, Inc. |
Topical formulations
|
|
CN113473986B
(zh)
|
2018-11-20 |
2024-10-11 |
恩福莱克逊治疗有限公司 |
用于治疗皮肤疾病萘啶酮苯胺化合物
|
|
AU2019383311B2
(en)
|
2018-11-20 |
2024-12-05 |
Nflection Therapeutics, Inc. |
Cyanoaryl-aniline compounds for treatment of dermal disorders
|
|
WO2020106307A1
(en)
|
2018-11-20 |
2020-05-28 |
Nflection Therapeutics, Inc. |
Aryl-aniline and heteroaryl-aniline compounds for treatment of birthmarks
|
|
EP4216952A4
(en)
|
2020-09-24 |
2024-11-20 |
NFlection Therapeutics, Inc. |
TREATMENT OF COGNITIVE DYSFUNCTION WITH PYRROLOPYRIDINE-ANILINE COMPOUNDS
|
|
JP2024503892A
(ja)
|
2021-01-21 |
2024-01-29 |
エヌフレクション セラピューティクス インコーポレイテッド |
ピロロピリジン－アニリン化合物の結晶形
|
|
US20240228480A1
(en)
|
2021-01-21 |
2024-07-11 |
Nflection Therapeutics, Inc. |
Processes for preparing pyrrolopyridine-aniline compounds
|