JPWO2020061478A5 - - Google Patents
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- JPWO2020061478A5 JPWO2020061478A5 JP2021515172A JP2021515172A JPWO2020061478A5 JP WO2020061478 A5 JPWO2020061478 A5 JP WO2020061478A5 JP 2021515172 A JP2021515172 A JP 2021515172A JP 2021515172 A JP2021515172 A JP 2021515172A JP WO2020061478 A5 JPWO2020061478 A5 JP WO2020061478A5
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- antibody
- elution buffer
- multispecific
- binding
- heavy chain
- Prior art date
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| CR20220578A (es) * | 2016-09-14 | 2023-01-17 | Teneobio Inc | Anticuerpos de unión a cd3 |
| JP7240335B2 (ja) | 2017-06-20 | 2023-03-15 | テネオワン， インコーポレイテッド | 抗ｂｃｍａ重鎖のみ抗体 |
| EA202091557A1 (ru) | 2017-12-22 | 2020-11-18 | Тенеобио, Инк. | Антитела, содержащие только тяжелые цепи, которые связываются с cd22 |
| PE20220575A1 (es) | 2019-06-14 | 2022-04-20 | Teneobio Inc | Anticuerpos multiespecificos de cadena pesada que se unen a cd22 y cd3 |
| IL297601A (en) * | 2020-04-29 | 2022-12-01 | Teneobio Inc | Multispecific heavy chain antibodies with modified heavy chain constant regions |
| CN114539417A (zh) * | 2020-11-26 | 2022-05-27 | 盛禾(中国)生物制药有限公司 | 一种有效去除双特异性抗体同源二聚体的层析纯化工艺 |
| CN117242095A (zh) * | 2021-04-23 | 2023-12-15 | 和铂医药(上海)有限责任公司 | 一种双特异性抗体的纯化方法 |
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| US4560655A (en) | 1982-12-16 | 1985-12-24 | Immunex Corporation | Serum-free cell culture medium and process for making same |
| US4657866A (en) | 1982-12-21 | 1987-04-14 | Sudhir Kumar | Serum-free, synthetic, completely chemically defined tissue culture media |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US4767704A (en) | 1983-10-07 | 1988-08-30 | Columbia University In The City Of New York | Protein-free culture medium |
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| IL85035A0 (en) | 1987-01-08 | 1988-06-30 | Int Genetic Eng | Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same |
| ATE135397T1 (de) | 1988-09-23 | 1996-03-15 | Cetus Oncology Corp | Zellenzuchtmedium für erhöhtes zellenwachstum, zur erhöhung der langlebigkeit und expression der produkte |
| US5122469A (en) | 1990-10-03 | 1992-06-16 | Genentech, Inc. | Method for culturing Chinese hamster ovary cells to improve production of recombinant proteins |
| EP0940468A1 (en) | 1991-06-14 | 1999-09-08 | Genentech, Inc. | Humanized antibody variable domain |
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| DE19836213A1 (de) * | 1998-08-11 | 2000-02-24 | Gerhard Harry Scholz | Verfahren zur Elution von Biomolekülen von Chromatographie-Materialien |
| US20040220388A1 (en) * | 2000-06-30 | 2004-11-04 | Nico Mertens | Novel heterodimeric fusion proteins |
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| JP2014515598A (ja) * | 2011-03-10 | 2014-07-03 | エイチシーオー アンティボディ， インク． | 二重特異性三鎖抗体様分子 |
| DK2825559T3 (da) * | 2012-03-13 | 2019-06-03 | Novimmune Sa | Letisolerbare bispecifikke antistoffer med nativt immunoglobulinformat |
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| EP3280444B1 (en) * | 2015-04-10 | 2024-05-08 | Adimab, LLC | Methods for purifying heterodimeric multispecific antibodies from parental homodimeric antibody species |
| CN107446044B (zh) * | 2016-05-30 | 2021-04-30 | 越海百奥药业(绍兴)有限公司 | 一种纯化抗体的方法及所用缓冲液 |
| US11312745B2 (en) * | 2016-07-22 | 2022-04-26 | Amgen Inc. | Methods of purifying Fc-containing proteins |
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-
2019
- 2019-09-20 KR KR1020217010141A patent/KR20210063354A/ko unknown
- 2019-09-20 MX MX2021003169A patent/MX2021003169A/es unknown
- 2019-09-20 AU AU2019343053A patent/AU2019343053A1/en active Pending
- 2019-09-20 SG SG11202102713TA patent/SG11202102713TA/en unknown
- 2019-09-20 CN CN201980066235.1A patent/CN112839959A/zh active Pending
- 2019-09-20 BR BR112021004680-1A patent/BR112021004680A2/pt unknown
- 2019-09-20 EP EP19787122.1A patent/EP3853253A2/en active Pending
- 2019-09-20 JP JP2021515172A patent/JP2022501357A/ja active Pending
- 2019-09-20 WO PCT/US2019/052199 patent/WO2020061478A2/en unknown
- 2019-09-20 CA CA3113057A patent/CA3113057A1/en active Pending
- 2019-09-20 US US17/278,268 patent/US20210355215A1/en active Pending
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2021
- 2021-03-16 IL IL281570A patent/IL281570A/en unknown
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