JPWO2020050273A1 - グルタチオンの製造方法 - Google Patents

グルタチオンの製造方法 Download PDF

Info

Publication number
JPWO2020050273A1
JPWO2020050273A1 JP2020541239A JP2020541239A JPWO2020050273A1 JP WO2020050273 A1 JPWO2020050273 A1 JP WO2020050273A1 JP 2020541239 A JP2020541239 A JP 2020541239A JP 2020541239 A JP2020541239 A JP 2020541239A JP WO2020050273 A1 JPWO2020050273 A1 JP WO2020050273A1
Authority
JP
Japan
Prior art keywords
amino acid
glutathione
yeast
acid sequence
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2020541239A
Other languages
English (en)
Japanese (ja)
Inventor
裕一 岩本
裕一 岩本
晃 岩崎
晃 岩崎
祐章 加藤
祐章 加藤
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kaneka Corp
Original Assignee
Kaneka Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kaneka Corp filed Critical Kaneka Corp
Publication of JPWO2020050273A1 publication Critical patent/JPWO2020050273A1/ja
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2020541239A 2018-09-07 2019-09-03 グルタチオンの製造方法 Pending JPWO2020050273A1 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2018167655 2018-09-07
JP2018167655 2018-09-07
PCT/JP2019/034630 WO2020050273A1 (fr) 2018-09-07 2019-09-03 Procédé de production de glutathion

Publications (1)

Publication Number Publication Date
JPWO2020050273A1 true JPWO2020050273A1 (ja) 2021-08-30

Family

ID=69722364

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020541239A Pending JPWO2020050273A1 (ja) 2018-09-07 2019-09-03 グルタチオンの製造方法

Country Status (3)

Country Link
JP (1) JPWO2020050273A1 (fr)
CN (1) CN112639117A (fr)
WO (1) WO2020050273A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102354283B1 (ko) * 2020-04-03 2022-01-21 씨제이제일제당 주식회사 신규한 프로모터 및 이를 이용한 글루타치온 생산 방법
CN115747089A (zh) * 2022-07-06 2023-03-07 河南省巴饲福微生物技术研究院 一种生产谷胱甘肽的重组酿酒酵母菌及其构建方法

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01148181A (ja) * 1987-12-07 1989-06-09 Jgc Corp グルタチオンの菌体内蓄積法
JP2004180509A (ja) * 2002-11-29 2004-07-02 Kanegafuchi Chem Ind Co Ltd グルタチオン高含有酵母およびそれを培養して得られる食品又は医薬品、又は化粧品用素材
WO2011118807A1 (fr) * 2010-03-26 2011-09-29 アサヒビール株式会社 Procédé de culture de levure
JP2013169168A (ja) * 2012-02-20 2013-09-02 Kaneka Corp グルタチオンの製造方法
JP2014064472A (ja) * 2012-09-24 2014-04-17 Kaneka Corp グルタチオンの製造方法
KR20150071264A (ko) * 2013-12-18 2015-06-26 (주)푸른들이엠사료 글루타치온을 고발현하는 신규 균주 및 글루타치온 대량 생산 방법
WO2016140349A1 (fr) * 2015-03-04 2016-09-09 株式会社カネカ Procédé de production de glutathion

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01148181A (ja) * 1987-12-07 1989-06-09 Jgc Corp グルタチオンの菌体内蓄積法
JP2004180509A (ja) * 2002-11-29 2004-07-02 Kanegafuchi Chem Ind Co Ltd グルタチオン高含有酵母およびそれを培養して得られる食品又は医薬品、又は化粧品用素材
WO2011118807A1 (fr) * 2010-03-26 2011-09-29 アサヒビール株式会社 Procédé de culture de levure
JP2013169168A (ja) * 2012-02-20 2013-09-02 Kaneka Corp グルタチオンの製造方法
JP2014064472A (ja) * 2012-09-24 2014-04-17 Kaneka Corp グルタチオンの製造方法
KR20150071264A (ko) * 2013-12-18 2015-06-26 (주)푸른들이엠사료 글루타치온을 고발현하는 신규 균주 및 글루타치온 대량 생산 방법
WO2016140349A1 (fr) * 2015-03-04 2016-09-09 株式会社カネカ Procédé de production de glutathion

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CURRENT TRENDS IN BIOTECHNOLOGY AND PHARMACY, vol. 6, no. 2, JPN6019044612, 2012, pages 241 - 254, ISSN: 0005190598 *

Also Published As

Publication number Publication date
CN112639117A (zh) 2021-04-09
WO2020050273A1 (fr) 2020-03-12

Similar Documents

Publication Publication Date Title
JP5874286B2 (ja) γ−グルタミル化合物を含有する酵母エキスの製造方法及び当該方法に用いられる酵母
JP5857973B2 (ja) γ−Glu−X又はγ−Glu−X−Gly含有酵母エキス及びその製造方法
JP6799738B2 (ja) グルタチオンの製造方法
WO2009131179A1 (fr) Levure mutante et procédé de production de substances à l’aide de cette dernière
WO2013054447A1 (fr) Procédé de production de γ-glu-x-gly ou d'un sel de celui-ci, et glutathion synthase mutante
JPWO2020050273A1 (ja) グルタチオンの製造方法
JP6489014B2 (ja) Abu、γ−Glu−Abu、及び/又はγ−Glu−Abu−Glyを高含有する酵母
JPWO2009110624A1 (ja) γ−グルタミルシステイン生産酵母及び酵母エキスの製造法
JPWO2012046731A1 (ja) γ−Glu−Abuを含有する酵母及び酵母エキス、並びにそれらの製造方法
EP4219697A1 (fr) Variant de glutamate-cystéine ligase et procédé de production de glutathion l'utilisant
JP2005073638A (ja) キャンディダ・ユティリスのグルタチオン合成酵素をコードする遺伝子
JP2014064472A (ja) グルタチオンの製造方法
JP5998589B2 (ja) γ−Glu−Xを含有する酵母
WO2015111462A1 (fr) PROCÉDÉ DE PRODUCTION DE γ-Glu-Abu ET PROCÉDÉ DE PRODUCTION D'EXTRAIT DE LEVURE CONTENANT Γ-Glu-Abu
KR102605543B1 (ko) 메티오닌-생산 효모
JP2012125170A (ja) チオール化合物高生産微生物
JP5673669B2 (ja) 含硫化合物含量が増加した酵母、そのスクリーニング方法、及び培養方法
JP6020875B2 (ja) グルタチオンの製造方法
RU2821273C1 (ru) Вариант глутамат-цистеинлигазы и способ получения глутатиона с его использованием
JP2004113155A (ja) γ−グルタミルシステインの製造法
JP2016049074A (ja) γ−Glu−Abu及び/又はγ−Glu−Abu−Glyを高含有する酵母
JP2011103789A (ja) グルタチオン高生産酵母及びその利用
JP2004173503A (ja) γ−グルタミルシステイン合成酵素及びこれをコーディングする遺伝子

Legal Events

Date Code Title Description
A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20220725

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20230725

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20230920

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20231107

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20240423