JPWO2020018506A5 - - Google Patents

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JPWO2020018506A5
JPWO2020018506A5 JP2021501337A JP2021501337A JPWO2020018506A5 JP WO2020018506 A5 JPWO2020018506 A5 JP WO2020018506A5 JP 2021501337 A JP2021501337 A JP 2021501337A JP 2021501337 A JP2021501337 A JP 2021501337A JP WO2020018506 A5 JPWO2020018506 A5 JP WO2020018506A5
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JP
Japan
Prior art keywords
bacterial cell
steviol glycoside
glucose
ugt
expression
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JP2021501337A
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English (en)
Japanese (ja)
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JP7305087B2 (ja
JP2021530228A (ja
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Priority claimed from PCT/US2019/041957 external-priority patent/WO2020018506A2/en
Publication of JP2021530228A publication Critical patent/JP2021530228A/ja
Publication of JPWO2020018506A5 publication Critical patent/JPWO2020018506A5/ja
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JP2021501337A 2018-07-16 2019-07-16 全細胞生体内変換によるステビオールグリコシドの産生 Active JP7305087B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862698617P 2018-07-16 2018-07-16
US62/698,617 2018-07-16
PCT/US2019/041957 WO2020018506A2 (en) 2018-07-16 2019-07-16 Production of steviol glycosides through whole cell biotransformation

Publications (3)

Publication Number Publication Date
JP2021530228A JP2021530228A (ja) 2021-11-11
JPWO2020018506A5 true JPWO2020018506A5 (ko) 2022-07-26
JP7305087B2 JP7305087B2 (ja) 2023-07-10

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JP2021501337A Active JP7305087B2 (ja) 2018-07-16 2019-07-16 全細胞生体内変換によるステビオールグリコシドの産生

Country Status (12)

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US (2) US11230724B2 (ko)
EP (1) EP3824093A4 (ko)
JP (1) JP7305087B2 (ko)
KR (1) KR102532079B1 (ko)
CN (1) CN112867799A (ko)
AU (1) AU2019304965A1 (ko)
BR (1) BR112021000876A2 (ko)
CA (1) CA3106633A1 (ko)
IL (1) IL280151A (ko)
MX (1) MX2021000605A (ko)
SG (1) SG11202100450TA (ko)
WO (1) WO2020018506A2 (ko)

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EP3765627A4 (en) * 2018-03-12 2021-10-13 Conagen Inc. BIOSYNTHETIC PRODUCTION OF STEVIOL GLYCOSIDES REBAUDIOSIDE J AND REBAUDIOSIDE N
AU2019304965A1 (en) * 2018-07-16 2021-02-11 Manus Bio, Inc. Production of steviol glycosides through whole cell biotransformation
CN109295087B (zh) * 2018-11-09 2021-08-24 沈阳农业大学 一种表达制备udp-葡萄糖-己糖-1-磷酸尿苷酰转移酶的方法
CN109402152B (zh) * 2018-11-09 2021-08-13 沈阳农业大学 一种表达制备udp-葡萄糖-4-差向异构酶的方法
BR112021026306A2 (pt) * 2019-06-25 2022-09-06 Manus Bio Inc Enzima de glicosiltransferase dependente de uridina difosfato
CN110699373B (zh) * 2019-10-16 2023-05-26 中国药科大学 尿苷二磷酸葡萄糖高产菌株及其应用
CN111518825B (zh) * 2020-04-30 2022-10-11 浙江工业大学 一种多基因组合表达制备蛹虫草多糖的方法
US20230174993A1 (en) * 2020-05-13 2023-06-08 Ginkgo Bioworks, Inc. Biosynthesis of mogrosides
JP2024500432A (ja) * 2020-12-23 2024-01-09 サムヤン コーポレイション 糖転移酵素およびこれを用いたステビオール配糖体の製造方法
WO2023000243A1 (zh) * 2021-07-22 2023-01-26 深圳先进技术研究院 重组酵母生物转化生产葡萄糖的方法
KR20230098493A (ko) * 2021-12-24 2023-07-04 주식회사 삼양사 레바우디오사이드의 생산
CN114540396A (zh) * 2022-02-24 2022-05-27 天津大学 希瓦氏菌株中葡萄糖代谢通路的构建方法
CN114561310B (zh) * 2022-03-17 2022-12-02 江南大学 一种生产甜茶苷的酿酒酵母及其应用
WO2024121721A1 (en) * 2022-12-05 2024-06-13 Tate & Lyle Solutions Usa Llc Methods for obtaining steviol glycosides

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6586214B1 (en) * 1999-09-15 2003-07-01 Degussa Ag Method for increasing the metabolic flux through the pentose phosphate cycle in coryneform bacteria by regulation of the phosphoglucose isomerase (pgi gene)
CN105671108A (zh) * 2010-06-02 2016-06-15 沃维公司 甜菊糖苷的重组生产
EP3009508B1 (en) * 2011-08-08 2020-11-25 Evolva SA Recombinant production of steviol glycosides
CN110358795A (zh) 2012-05-22 2019-10-22 谱赛科有限责任公司 高纯度的甜菊醇糖苷
CN103397064B (zh) 2013-08-14 2015-04-15 苏州汉酶生物技术有限公司 一种酶法制备瑞鲍迪甙m的方法
WO2016073740A1 (en) 2014-11-05 2016-05-12 Manus Biosynthesis, Inc. Microbial production of steviol glycosides
EP3274448B1 (en) * 2015-03-23 2021-08-11 DSM IP Assets B.V. Udp-glycosyltransferases from solanum lycopersicum
KR101669041B1 (ko) 2015-03-31 2016-10-25 아주대학교산학협력단 스테비오사이드 생산능을 가지는 재조합 미생물 및 이를 이용한 스테비오사이드의 생산 방법
US20190169664A1 (en) 2016-05-06 2019-06-06 University Of Georgia Research Foundation, Inc. Microbial platform for production of glycosylated compounds
WO2018144679A2 (en) * 2017-02-03 2018-08-09 Codexis, Inc. Engineered glycosyltransferases and steviol glycoside glucosylation methods
AU2019304965A1 (en) * 2018-07-16 2021-02-11 Manus Bio, Inc. Production of steviol glycosides through whole cell biotransformation
BR112021026306A2 (pt) * 2019-06-25 2022-09-06 Manus Bio Inc Enzima de glicosiltransferase dependente de uridina difosfato

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