JPWO2020017620A5 - - Google Patents
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- Publication number
- JPWO2020017620A5 JPWO2020017620A5 JP2020531374A JP2020531374A JPWO2020017620A5 JP WO2020017620 A5 JPWO2020017620 A5 JP WO2020017620A5 JP 2020531374 A JP2020531374 A JP 2020531374A JP 2020531374 A JP2020531374 A JP 2020531374A JP WO2020017620 A5 JPWO2020017620 A5 JP WO2020017620A5
- Authority
- JP
- Japan
- Prior art keywords
- salt
- fatty acid
- acid derivative
- labeled fatty
- heart disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000003839 salts Chemical class 0.000 claims 16
- 235000014113 dietary fatty acids Nutrition 0.000 claims 13
- 229930195729 fatty acid Natural products 0.000 claims 13
- 239000000194 fatty acid Substances 0.000 claims 13
- 150000004665 fatty acids Chemical class 0.000 claims 13
- 208000019622 heart disease Diseases 0.000 claims 7
- 238000002059 diagnostic imaging Methods 0.000 claims 6
- 150000001875 compounds Chemical class 0.000 claims 5
- 208000031225 myocardial ischemia Diseases 0.000 claims 3
- 125000000217 alkyl group Chemical group 0.000 claims 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 2
- KZLMDUNDGBJYQB-AVGIDEFSSA-N 3-[(Z)-2-(18F)fluoranyltetradec-5-enyl]sulfanylpropanoic acid Chemical group [18F]C(CSCCC(=O)O)CC\C=C/CCCCCCCC KZLMDUNDGBJYQB-AVGIDEFSSA-N 0.000 claims 1
- XLHOLOJPVDSSDQ-AVGIDEFSSA-N 3-[(Z)-3-(18F)fluoranyltetradec-5-enyl]sulfanylpropanoic acid Chemical group [18F]C(CCSCCC(=O)O)C\C=C/CCCCCCCC XLHOLOJPVDSSDQ-AVGIDEFSSA-N 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- KRHYYFGTRYWZRS-BJUDXGSMSA-M fluorine-18(1-) Chemical compound [18F-] KRHYYFGTRYWZRS-BJUDXGSMSA-M 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2018136483 | 2018-07-20 | ||
| JP2018136483 | 2018-07-20 | ||
| PCT/JP2019/028380 WO2020017620A1 (ja) | 2018-07-20 | 2019-07-19 | 陽電子放出核種で標識された脂肪酸誘導体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JPWO2020017620A1 JPWO2020017620A1 (ja) | 2021-08-02 |
| JPWO2020017620A5 true JPWO2020017620A5 (https=) | 2022-06-20 |
| JP7375755B2 JP7375755B2 (ja) | 2023-11-08 |
Family
ID=69164918
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020531374A Active JP7375755B2 (ja) | 2018-07-20 | 2019-07-19 | 陽電子放出核種で標識された脂肪酸誘導体 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US12029797B2 (https=) |
| EP (1) | EP3825302B1 (https=) |
| JP (1) | JP7375755B2 (https=) |
| KR (1) | KR102718221B1 (https=) |
| CN (1) | CN112638868B (https=) |
| AU (1) | AU2019304781B2 (https=) |
| CA (1) | CA3106903A1 (https=) |
| ES (1) | ES3009015T3 (https=) |
| WO (1) | WO2020017620A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES3009015T3 (en) | 2018-07-20 | 2025-03-25 | Astellas Pharma Inc | Fatty acid derivative labeled with positron-emitting radionuclide |
| US20230065079A1 (en) * | 2020-01-17 | 2023-03-02 | Astellas Pharma Inc. | Fatty acid derivative labeled with positron-emitting radionuclide |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2828623C2 (de) | 1978-06-29 | 1983-11-17 | Kernforschungsanlage Jülich GmbH, 5170 Jülich | Mit radioaktivem Flour markierte C↓1↓↓6↓-bis C↓1↓↓8↓- Fettsäuren, ein Verfahren zu ihrer Herstellung sowie deren Verwendung |
| WO2000063216A1 (en) | 1999-04-19 | 2000-10-26 | Duke University | F-18-labeled thia fatty acids and methods of making and using the same |
| CA2522737C (en) * | 2003-04-17 | 2017-06-06 | The General Hospital Corporation | Method for monitoring blood flow and metabolic uptake in tissue with radiolabeled alkanoic acid |
| CN1217924C (zh) | 2003-10-17 | 2005-09-07 | 江苏省原子医学研究所 | 一种氟标记脂肪酸心肌代谢显像剂14(r,s)－氟[18f]－6－硫十七烷酸的纯化方法 |
| CA2760334A1 (en) | 2009-05-04 | 2010-11-11 | Washington University | Pet radiotracers for imaging fatty acid metabolism and storage |
| WO2014179341A1 (en) | 2013-04-29 | 2014-11-06 | Matinas Biopharma, Inc. | Treatment with omega-3 fatty acid compositions |
| WO2015023631A2 (en) | 2013-08-12 | 2015-02-19 | Carolyn Anderson | Fatty acid analogs and their use |
| CN105523977B (zh) | 2016-02-04 | 2017-05-24 | 河南中医学院 | [11c]‑巯甲基脂肪酸的制备方法与应用 |
| ES3009015T3 (en) | 2018-07-20 | 2025-03-25 | Astellas Pharma Inc | Fatty acid derivative labeled with positron-emitting radionuclide |
| US20230065079A1 (en) | 2020-01-17 | 2023-03-02 | Astellas Pharma Inc. | Fatty acid derivative labeled with positron-emitting radionuclide |
-
2019
- 2019-07-19 ES ES19837826T patent/ES3009015T3/es active Active
- 2019-07-19 KR KR1020217001389A patent/KR102718221B1/ko active Active
- 2019-07-19 JP JP2020531374A patent/JP7375755B2/ja active Active
- 2019-07-19 US US17/261,328 patent/US12029797B2/en active Active
- 2019-07-19 EP EP19837826.7A patent/EP3825302B1/en active Active
- 2019-07-19 CN CN201980048149.8A patent/CN112638868B/zh active Active
- 2019-07-19 CA CA3106903A patent/CA3106903A1/en active Pending
- 2019-07-19 AU AU2019304781A patent/AU2019304781B2/en active Active
- 2019-07-19 WO PCT/JP2019/028380 patent/WO2020017620A1/ja not_active Ceased
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