|
ATE78293T1
(de)
|
1983-05-27 |
1992-08-15 |
Texas A & M Univ Sys |
Verfahren zur herstellung eines rekombinanten baculovirus-expressionsvektors.
|
|
ZA848495B
(en)
|
1984-01-31 |
1985-09-25 |
Idaho Res Found |
Production of polypeptides in insect cells
|
|
US5449616A
(en)
|
1990-05-23 |
1995-09-12 |
University Of Iowa Research Foundation |
Nucleic acid encoding dystrophin-associated protein
|
|
US5173414A
(en)
|
1990-10-30 |
1992-12-22 |
Applied Immune Sciences, Inc. |
Production of recombinant adeno-associated virus vectors
|
|
AU7345394A
(en)
|
1993-07-23 |
1995-02-20 |
Unichema Chemie Bv |
Process for producing transparent soap material
|
|
ATE272123T1
(de)
|
1993-11-09 |
2004-08-15 |
Ohio Med College |
Stabile zellinie, die in der lage ist, das replikationsgen des adenoassoziertenvirus zu exprimieren
|
|
EP0733103B1
(en)
|
1993-11-09 |
2004-03-03 |
Targeted Genetics Corporation |
Generation of high titers of recombinant aav vectors
|
|
US5658785A
(en)
|
1994-06-06 |
1997-08-19 |
Children's Hospital, Inc. |
Adeno-associated virus materials and methods
|
|
US6204059B1
(en)
|
1994-06-30 |
2001-03-20 |
University Of Pittsburgh |
AAV capsid vehicles for molecular transfer
|
|
US5856152A
(en)
|
1994-10-28 |
1999-01-05 |
The Trustees Of The University Of Pennsylvania |
Hybrid adenovirus-AAV vector and methods of use therefor
|
|
EP0796339A1
(en)
|
1994-12-06 |
1997-09-24 |
Targeted Genetics Corporation |
Packaging cell lines for generation of high titers of recombinant aav vectors
|
|
FR2737730B1
(fr)
|
1995-08-10 |
1997-09-05 |
Pasteur Merieux Serums Vacc |
Procede de purification de virus par chromatographie
|
|
JPH11511326A
(ja)
|
1995-08-30 |
1999-10-05 |
ジエンザイム コーポレイション |
アデノウィルスおよびaavの精製
|
|
US6632670B1
(en)
|
1995-09-08 |
2003-10-14 |
Genzyme Corporation |
AAV vectors for gene therapy
|
|
US5672694A
(en)
|
1995-10-24 |
1997-09-30 |
University Of Iowa Research Foundation |
β-sarcoglycan nucleic acid sequence, and nucleic acid probes
|
|
US5910434A
(en)
|
1995-12-15 |
1999-06-08 |
Systemix, Inc. |
Method for obtaining retroviral packaging cell lines producing high transducing efficiency retroviral supernatant
|
|
ATE465267T1
(de)
|
1996-09-06 |
2010-05-15 |
Univ Pennsylvania |
Rekombinante aav zur herstellung eines medikaments für die gentherapie von muskelzellen
|
|
US5843078A
(en)
|
1997-07-01 |
1998-12-01 |
Sharkey; Hugh R. |
Radio frequency device for resurfacing skin and method
|
|
WO1999011764A2
(en)
|
1997-09-05 |
1999-03-11 |
Targeted Genetics Corporation |
Methods for generating high titer helper-free preparations of recombinant aav vectors
|
|
US6566118B1
(en)
|
1997-09-05 |
2003-05-20 |
Targeted Genetics Corporation |
Methods for generating high titer helper-free preparations of released recombinant AAV vectors
|
|
WO1999043360A1
(en)
|
1998-02-26 |
1999-09-02 |
The Trustees Of The University Of Pennsylvania |
Stable protection from dystrophic sarcolemmal degeneration and restoration of the sarcoglycan complex
|
|
US6262035B1
(en)
|
1998-10-01 |
2001-07-17 |
University Of Iowa Research Foundation |
Gene replacement therapy for muscular dystrophy
|
|
US6258595B1
(en)
|
1999-03-18 |
2001-07-10 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for helper-free production of recombinant adeno-associated viruses
|
|
US6632800B1
(en)
|
1999-08-17 |
2003-10-14 |
Mayo Foundation For Medical Education And Research |
System for monitoring the expression of transgenes
|
|
JP4520569B2
(ja)
|
2000-02-18 |
2010-08-04 |
照彦 豊岡 |
拡張型心筋症の遺伝子治療剤
|
|
CA2406743A1
(en)
|
2000-04-28 |
2001-11-08 |
The Trustees Of The University Of Pennsylvania |
Recombinant aav vectors with aav5 capsids and aav5 vectors pseudotyped in heterologous capsids
|
|
AU2002248297A1
(en)
|
2001-01-05 |
2002-07-16 |
Children's Hospital, Inc. |
Aav2 vectors and methods
|
|
CA2455884C
(en)
|
2001-08-15 |
2015-09-22 |
Justin R. Fallon |
Treatment of muscular dystrophies and related disorders
|
|
US20040126762A1
(en)
|
2002-12-17 |
2004-07-01 |
Morris David W. |
Novel compositions and methods in cancer
|
|
ES2602352T3
(es)
|
2001-12-17 |
2017-02-20 |
The Trustees Of The University Of Pennsylvania |
Secuencias de serotipo 8 de virus adenoasociado (VAA), vectores que las contienen y usos de las mismas
|
|
WO2003074714A1
(en)
|
2002-03-05 |
2003-09-12 |
Stichting Voor De Technische Wetenschappen |
Baculovirus expression system
|
|
US7858367B2
(en)
|
2002-04-30 |
2010-12-28 |
Duke University |
Viral vectors and methods for producing and using the same
|
|
US20030225260A1
(en)
|
2002-04-30 |
2003-12-04 |
Snyder Richard O. |
Production of recombinant AAV virions
|
|
EP4170024A1
(en)
|
2004-06-01 |
2023-04-26 |
Genzyme Corporation |
Compositions and methods to prevent aav vector aggregation
|
|
US7972593B2
(en)
|
2004-06-10 |
2011-07-05 |
Saint Louis University |
Delivery of therapeutic agents to the bone
|
|
WO2006039218A2
(en)
|
2004-09-30 |
2006-04-13 |
The Trustees Of The University Of Pennsylvania |
Perfusion circuit and use therein in targeted delivery of macromolecules
|
|
JP2006121961A
(ja)
|
2004-10-28 |
2006-05-18 |
Univ Of Tokushima |
顎骨骨幹異形成症gddの原因遺伝子gdd1とその用途
|
|
US7883858B2
(en)
|
2005-01-27 |
2011-02-08 |
Institute For Systems Biology |
Methods for identifying and monitoring drug side effects
|
|
US7788045B2
(en)
|
2005-09-01 |
2010-08-31 |
Meditasks, Llc |
Systems and method for homeostatic blood states
|
|
CA2625403A1
(en)
|
2005-10-17 |
2007-04-26 |
Institute For System Biology |
Tissue-and serum-derived glycoproteins and methods of their use
|
|
WO2007049095A1
(en)
|
2005-10-25 |
2007-05-03 |
Cellectis |
Laglidadg homing endonuclease variants having mutations in two functional subdomains and use thereof
|
|
EP2018421B1
(en)
|
2006-04-28 |
2012-12-19 |
The Trustees of the University of Pennsylvania |
Scalable production method for aav
|
|
US20100120627A1
(en)
|
2006-08-02 |
2010-05-13 |
Abdelmajid Belouchi |
Genemap of the human genes associated with psoriasis
|
|
JP5244103B2
(ja)
|
2006-08-09 |
2013-07-24 |
ホームステッド クリニカル コーポレイション |
器官特異的蛋白質およびその使用方法
|
|
WO2008058273A2
(en)
|
2006-11-09 |
2008-05-15 |
The Johns Hopkins University |
Dedifferentiation of adult mammalian cardiomyocytes into cardiac stem cells
|
|
JP5575486B2
(ja)
|
2007-01-18 |
2014-08-20 |
ユニヴァーシティ オブ ミズーリー−コロンビア |
筋鞘にnNOSを回復させる合成ミニ/ミクロジストロフィン遺伝子
|
|
FR2919305B1
(fr)
|
2007-07-26 |
2009-09-18 |
Genethon Ass Loi De 1901 |
Vecteurs viraux adeno-associes pour l'expression de la dysferline.
|
|
GB0715087D0
(en)
|
2007-08-03 |
2007-09-12 |
Summit Corp Plc |
Drug combinations for the treatment of duchenne muscular dystrophy
|
|
PT2203173E
(pt)
|
2007-10-26 |
2016-03-15 |
Academisch Ziekenhuis Leiden |
Resumo
|
|
US8236527B2
(en)
|
2008-03-14 |
2012-08-07 |
Humanzyme Limited |
Recombinant production of authentic human proteins using human cell expression systems
|
|
US20090280103A1
(en)
|
2008-04-04 |
2009-11-12 |
Martin Flueck |
Regulation of muscle repair
|
|
US8632764B2
(en)
|
2008-04-30 |
2014-01-21 |
University Of North Carolina At Chapel Hill |
Directed evolution and in vivo panning of virus vectors
|
|
US8236557B2
(en)
|
2008-05-28 |
2012-08-07 |
University Of Missouri-Columbia |
Hybrid-AAV vectors to deliver large gene expression cassette
|
|
US20100026655A1
(en)
|
2008-07-31 |
2010-02-04 |
Avago Technologies Ecbu Ip (Singapore) Pte. Ltd. |
Capacitive Touchscreen or Touchpad for Finger or Stylus
|
|
US8729041B2
(en)
|
2008-12-03 |
2014-05-20 |
The Johns Hopkins University |
Compositions and methods for treating hepatic neoplasia
|
|
US20110023139A1
(en)
|
2008-12-04 |
2011-01-27 |
Sigma-Aldrich Co. |
Genomic editing of genes involved in cardiovascular disease
|
|
US20100247495A1
(en)
|
2009-03-30 |
2010-09-30 |
Tom Ichim |
Treatment of Muscular Dystrophy
|
|
WO2011044138A1
(en)
|
2009-10-05 |
2011-04-14 |
Catabasis Pharmaceuticals, Inc. |
Lipoic acid acylated salicylate derivatives and their uses
|
|
KR101841752B1
(ko)
|
2009-11-03 |
2018-05-04 |
더 리전트 오브 더 유니버시티 오브 캘리포니아 |
저온 수용액 내에서 성장한 다중 표면들 상의 산화 아연 층들에 의해 커버되는 고휘도 발광 다이오드
|
|
FR2962041B1
(fr)
|
2010-07-01 |
2012-07-27 |
Genethon |
Inhibiteurs de la calpaine 3 pour le traitement de dystrophies musculaires et de cardiomyopathies
|
|
ES2990023T3
(es)
|
2011-07-25 |
2024-11-28 |
Nationwide Childrens Hospital Inc |
Productos de virus recombinantes y métodos para inhibición de la expresión de DUX4
|
|
WO2013075008A1
(en)
|
2011-11-16 |
2013-05-23 |
University Of Florida Research Foundation Inc. |
Aav dual vector systems for gene therapy
|
|
WO2013078316A1
(en)
|
2011-11-23 |
2013-05-30 |
Nationwide Children's Hospital, Inc. |
Recombinant adeno-associated virus delivery of alpha-sarcoglycan polynucleotides
|
|
BR112014020325A2
(pt)
|
2012-02-17 |
2017-08-08 |
Childrens Hospital Philadelphia |
composições de vetor do aav e métodos para a transferência de gene para as células, órgãos e tecidos
|
|
DE18200782T1
(de)
|
2012-04-02 |
2021-10-21 |
Modernatx, Inc. |
Modifizierte polynukleotide zur herstellung von proteinen im zusammenhang mit erkrankungen beim menschen
|
|
US9878056B2
(en)
|
2012-04-02 |
2018-01-30 |
Modernatx, Inc. |
Modified polynucleotides for the production of cosmetic proteins and peptides
|
|
DE102012007232B4
(de)
|
2012-04-07 |
2014-03-13 |
Susanne Weller |
Verfahren zur Herstellung von rotierenden elektrischen Maschinen
|
|
FI3597749T3
(fi)
|
2012-05-25 |
2023-10-09 |
Univ California |
Menetelmiä ja koostumuksia rna-ohjattua kohde-dna-modifikaatiota varten ja rna-ohjattua transkription modulaatiota varten
|
|
PT3421602T
(pt)
|
2012-09-06 |
2021-05-31 |
Univ Chicago |
Polinucleótidos antisenso para induzir o salto de exão e métodos de tratamentos de distrofias
|
|
WO2014037526A1
(en)
|
2012-09-07 |
2014-03-13 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
In vitro genetic diagnostic of inherited neuromuscular disorders
|
|
EP2900821B1
(en)
|
2012-09-25 |
2020-04-01 |
Genzyme Corporation |
Peptide-linked morpholino antisense oligonucleotides for treatment of myotonic dystrophy
|
|
US9624282B2
(en)
|
2012-11-26 |
2017-04-18 |
The Curators Of The University Of Missouri |
Microdystrophin peptides and methods for treating muscular dystrophy using the same
|
|
PT2784162E
(pt)
|
2012-12-12 |
2015-08-27 |
Broad Inst Inc |
Engenharia de sistemas, métodos e composições guia otimizadas para a manipulação de sequências
|
|
KR20150105956A
(ko)
|
2012-12-12 |
2015-09-18 |
더 브로드 인스티튜트, 인코퍼레이티드 |
서열 조작 및 치료적 적용을 위한 시스템, 방법 및 조성물의 전달, 유전자 조작 및 최적화
|
|
EP4234696A3
(en)
|
2012-12-12 |
2023-09-06 |
The Broad Institute Inc. |
Crispr-cas component systems, methods and compositions for sequence manipulation
|
|
FR3004463A1
(fr)
*
|
2013-04-11 |
2014-10-17 |
Genethon |
Systeme d'expression pour une therapie genique selective
|
|
CN105492611A
(zh)
|
2013-06-17 |
2016-04-13 |
布罗德研究所有限公司 |
用于序列操纵的优化的crispr-cas双切口酶系统、方法以及组合物
|
|
ITTO20130669A1
(it)
|
2013-08-05 |
2015-02-06 |
Consiglio Nazionale Ricerche |
Vettore adeno-associato ricombinante muscolo-specifico e suo impiego nel trattamento di patologie muscolari
|
|
TW201536329A
(zh)
|
2013-08-09 |
2015-10-01 |
Isis Pharmaceuticals Inc |
用於調節失養性肌強直蛋白質激酶(dmpk)表現之化合物及方法
|
|
JP2015092462A
(ja)
|
2013-09-30 |
2015-05-14 |
Tdk株式会社 |
正極及びそれを用いたリチウムイオン二次電池
|
|
HUE037179T2
(hu)
|
2013-10-08 |
2018-08-28 |
Ystem S R L |
Gyógyászati kompozíciók izom-rendellenességek kezelésére
|
|
US9850497B2
(en)
|
2013-11-04 |
2017-12-26 |
Regents Of The University Of Minnesota |
Gene targeting methods and tools
|
|
EP3079726B1
(en)
|
2013-12-12 |
2018-12-05 |
The Broad Institute, Inc. |
Delivery, use and therapeutic applications of the crispr-cas systems and compositions for targeting disorders and diseases using particle delivery components
|
|
CA2936726C
(en)
|
2014-01-21 |
2024-04-30 |
Vrije Universiteit Brussel |
Muscle-specific nucleic acid regulatory elements and methods and use thereof
|
|
WO2015141521A1
(ja)
|
2014-03-21 |
2015-09-24 |
株式会社日立国際電気 |
基板処理装置、半導体装置の製造方法及び記録媒体
|
|
DE102014207498A1
(de)
|
2014-04-17 |
2015-10-22 |
Universitätsklinikum Hamburg-Eppendorf |
Viraler Vektor für den zielgerichteten Gentransfer in Gehirn und Rückenmark
|
|
EP2960336A1
(en)
|
2014-06-27 |
2015-12-30 |
Genethon |
Efficient systemic treatment of dystrophic muscle pathologies
|
|
JP6197169B2
(ja)
|
2014-09-29 |
2017-09-20 |
東芝メモリ株式会社 |
半導体装置の製造方法
|
|
AU2016206518B2
(en)
|
2015-01-16 |
2020-03-05 |
University Of Washington |
Novel micro-dystrophins and related methods of use
|
|
KR102877920B1
(ko)
*
|
2015-11-16 |
2025-10-30 |
더 리서치 인스티튜트 앳 네이션와이드 칠드런스 하스피탈 |
티틴-기반 근증 및 다른 티틴성병증의 치료를 위한 물질 및 방법
|
|
WO2017165859A1
(en)
|
2016-03-24 |
2017-09-28 |
Research Institute At Nationwide Children's Hospital |
Modified viral capsid proteins
|
|
HUE066442T2
(hu)
|
2016-04-15 |
2024-08-28 |
Res Institute At Nationwide |
ß-szarkoglikán és mikroRNS-29 adenoasszociáltvírus-vektorral történõ bejuttatása és izomdisztrófia kezelése
|
|
MA45477A
(fr)
|
2016-04-15 |
2019-02-20 |
Res Inst Nationwide Childrens Hospital |
Administration à vecteurs de virus adéno-associé de microarn-29 et micro-dystrophine pour traiter la dystrophie musculaire
|
|
AU2017248659B2
(en)
|
2016-04-15 |
2022-08-11 |
The Trustees Of The University Of Pennsylvania |
Gene therapy for treating hemophilia A
|
|
CA2971303A1
(en)
|
2016-06-21 |
2017-12-21 |
Bamboo Therapeutics, Inc. |
Optimized mini-dystrophin genes and expression cassettes and their use
|
|
WO2018170408A1
(en)
|
2017-03-17 |
2018-09-20 |
Research Institute At Nationwide Children's Hospital, Inc. |
Adeno-associated virus vector delivery of muscle specific micro-dystrophin to treat muscular dystrophy
|
|
JP7162021B2
(ja)
|
2017-03-17 |
2022-10-27 |
ニューカッスル ユニバーシティ |
筋ジストロフィーを治療するためのマイクロジストロフィン断片のアデノ随伴ウイルスベクター送達
|
|
US11534501B2
(en)
|
2017-10-18 |
2022-12-27 |
Research Institute At Nationwide Children's Hospital |
Adeno-associated virus vector delivery of muscle specific micro-dystrophin to treat muscular dystrophy
|
|
EP3697916A4
(en)
|
2017-10-20 |
2021-08-11 |
Research Institute at Nationwide Children's Hospital |
METHODS AND MATERIALS FOR NT-3 GENE THERAPY
|
|
TW201936201A
(zh)
|
2017-12-14 |
2019-09-16 |
美商堅固生物科技公司 |
基因之非病毒生產及遞送
|
|
SG11202006722RA
(en)
|
2018-01-31 |
2020-08-28 |
Res Inst Nationwide Childrens Hospital |
Gene therapy for limb-girdle muscular dystrophy type 2c
|
|
JP2021520196A
(ja)
|
2018-04-03 |
2021-08-19 |
ザ・キュレイターズ・オブ・ザ・ユニバーシティー・オブ・ミズーリThe Curators Of The University Of Missouri |
ジストロフィン異常症(dystrophinopathy)治療のためのヒンジ1および/または4の改変ジストロフィン
|
|
US12152242B2
(en)
|
2018-04-23 |
2024-11-26 |
The Curators Of The University Of Missouri |
CRISPR therapy
|
|
MY208145A
(en)
|
2018-06-18 |
2025-04-18 |
Res Inst Nationwide Childrens Hospital |
Adeno-associated virus vector delivery of muscle specific micro-dystrophin to treat muscular dystrophy
|
|
US20220031865A1
(en)
|
2018-12-12 |
2022-02-03 |
Solid Biosciences Inc. |
Combination therapy for treating muscular dystrophy
|
|
CA3131390A1
(en)
|
2019-02-26 |
2020-09-03 |
Research Institute Of Nationwide Children's Hospital |
Adeno-associated virus vector delivery of b-sarcoglycan and the treatment of muscular dystrophy
|
|
HRP20240505T1
(hr)
|
2019-08-21 |
2024-07-05 |
Research Institute At Nationwide Children's Hospital |
Dostava alfa-sarkoglikana vektorom povezanim s adenovirusom i liječenje mišićne distrofije
|
|
WO2021257595A1
(en)
|
2020-06-15 |
2021-12-23 |
Research Institute At Nationwide Children's Hospital |
Adeno-associated virus vector delivery for muscular dystrophies
|
|
MX2022016243A
(es)
|
2020-06-17 |
2023-03-08 |
Acceleron Pharma Inc |
Antagonistas de actrii-alk4 y métodos para el tratamiento contra insuficiencia cardíaca.
|
|
US20230390417A1
(en)
*
|
2022-06-02 |
2023-12-07 |
Research Institute At Nationwide Children's Hospital |
Recombinant Adeno-Associated Virus Products and Methods for Treating Limb Girdle Muscular Dystrophy 2A
|