JPWO2019241442A5 - - Google Patents
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- JPWO2019241442A5 JPWO2019241442A5 JP2020569024A JP2020569024A JPWO2019241442A5 JP WO2019241442 A5 JPWO2019241442 A5 JP WO2019241442A5 JP 2020569024 A JP2020569024 A JP 2020569024A JP 2020569024 A JP2020569024 A JP 2020569024A JP WO2019241442 A5 JPWO2019241442 A5 JP WO2019241442A5
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- JP
- Japan
- Prior art keywords
- compound
- subject
- item
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- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 150000001875 compounds Chemical class 0.000 claims description 62
- 201000003895 major depressive disease Diseases 0.000 claims description 29
- 239000002775 capsule Substances 0.000 claims description 10
- 206010012378 Depression Diseases 0.000 claims description 9
- 230000003920 cognitive function Effects 0.000 claims description 8
- 201000009916 postpartum depression Diseases 0.000 claims description 7
- 206010054089 Depressive symptom Diseases 0.000 claims description 6
- 206010004939 Bipolar I disease Diseases 0.000 claims description 5
- 206010004938 Bipolar disease Diseases 0.000 claims description 5
- 206010057668 Cognitive disease Diseases 0.000 claims description 2
- 239000003814 drug Substances 0.000 claims description 2
- 239000000203 mixture Substances 0.000 claims 22
- 150000003839 salts Chemical class 0.000 claims 13
- 239000011780 sodium chloride Substances 0.000 claims 13
- 239000008194 pharmaceutical composition Substances 0.000 description 6
- 239000000463 material Substances 0.000 description 2
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023205211A JP2024028849A (ja) | 2018-06-12 | 2023-12-05 | １９－ノルｃ３，３－二置換ｃ２１－ｎ－ピラゾリルステロイドおよびその使用方法 |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862684155P | 2018-06-12 | 2018-06-12 | |
| US62/684,155 | 2018-06-12 | ||
| US201962789329P | 2019-01-07 | 2019-01-07 | |
| US62/789,329 | 2019-01-07 | ||
| US201962841645P | 2019-05-01 | 2019-05-01 | |
| US62/841,645 | 2019-05-01 | ||
| PCT/US2019/036848 WO2019241442A1 (en) | 2018-06-12 | 2019-06-12 | A 19-nor c3,3-disubstituted c21 -n-pyrazolyl steroid and methods of use thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023205211A Division JP2024028849A (ja) | 2018-06-12 | 2023-12-05 | １９－ノルｃ３，３－二置換ｃ２１－ｎ－ピラゾリルステロイドおよびその使用方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021527092A JP2021527092A (ja) | 2021-10-11 |
| JPWO2019241442A5 true JPWO2019241442A5 (ru) | 2022-06-16 |
Family
ID=67211854
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020569024A Pending JP2021527092A (ja) | 2018-06-12 | 2019-06-12 | １９−ノルｃ３，３−二置換ｃ２１−ｎ−ピラゾリルステロイドおよびその使用方法 |
| JP2023205211A Pending JP2024028849A (ja) | 2018-06-12 | 2023-12-05 | １９－ノルｃ３，３－二置換ｃ２１－ｎ－ピラゾリルステロイドおよびその使用方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023205211A Pending JP2024028849A (ja) | 2018-06-12 | 2023-12-05 | １９－ノルｃ３，３－二置換ｃ２１－ｎ－ピラゾリルステロイドおよびその使用方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US20210338692A1 (ru) |
| EP (1) | EP3806863A1 (ru) |
| JP (2) | JP2021527092A (ru) |
| KR (1) | KR20210021005A (ru) |
| CN (2) | CN112533611A (ru) |
| AU (1) | AU2019287491A1 (ru) |
| CA (1) | CA3103421A1 (ru) |
| IL (1) | IL279315A (ru) |
| MA (1) | MA52894A (ru) |
| MX (1) | MX2020013557A (ru) |
| SG (1) | SG11202012344RA (ru) |
| TW (1) | TW202005653A (ru) |
| WO (1) | WO2019241442A1 (ru) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112014018110B1 (pt) | 2012-01-23 | 2022-06-07 | Sage Therapeutics, Inc | Composições farmacêutica aquosas formuladas para administração parenteral e uso de alopregnanolona e sulfobutiléter-b-ciclodextrina |
| WO2015195962A1 (en) | 2014-06-18 | 2015-12-23 | Sage Therapeutics, Inc. | Neuroactive steroids, compositions, and uses thereof |
| ME03749B (me) | 2014-11-27 | 2021-04-20 | Sage Therapeutics Inc | KOMPOZICIJE I POSTUPCIZA LEČENJE POREMEĆAJA CNS-a |
| EP3504189A1 (en) | 2016-08-23 | 2019-07-03 | Sage Therapeutics, Inc. | A crystalline 19-nor c3, 3-disubstituted c21-n-pyrazolyl steroid |
| KR20200096596A (ko) | 2017-12-08 | 2020-08-12 | 세이지 테라퓨틱스, 인크. | Cns 장애의 치료를 위한 중수소화 21 -[4-시아노-피라졸-1 -일]-19-노르-프레간-3. 알파-올-20-온 유도체 |
| US20230018765A1 (en) * | 2019-12-05 | 2023-01-19 | Sage Therapeutics, Inc. | A 19-nor c3,3-disubstituted c21-n-pyrazolyl steroid and methods of use thereof |
| JP2023519241A (ja) | 2020-03-25 | 2023-05-10 | セージ セラピューティクス， インコーポレイテッド | 呼吸器状態の処置のための薬剤の使用 |
| KR20230041049A (ko) * | 2020-07-20 | 2023-03-23 | 세이지 테라퓨틱스, 인크. | 19-노르 c3,3-이치환된 c21-n-피라졸릴 스테로이드의 제형 및 이의 사용 방법 |
| KR20230158033A (ko) * | 2021-03-17 | 2023-11-17 | 세이지 테라퓨틱스, 인크. | 주요 우울 장애의 치료를 위한 19-노르 c3,3-이치환된 c21-n-피라졸릴 스테로이드 |
| JP2024515830A (ja) * | 2021-04-29 | 2024-04-10 | セージ セラピューティクス， インコーポレイテッド | 母乳を出している女性における大うつ病性障害および産後うつ病の処置における使用のための神経活性ステロイド |
| MX2023012727A (es) * | 2021-04-29 | 2023-11-08 | Sage Therapeutics Inc | Esteroide c21 -n-pirazolilo disubstituido 19-nor c3,3 para uso en el tratamiento de principales trastorno depresivo y depresion posparto. |
| WO2023158668A1 (en) * | 2022-02-16 | 2023-08-24 | Sage Therapeutics, Inc. | Neuroactive steroids for treatment of cns-related disorders |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108440633B (zh) * | 2013-04-17 | 2021-07-13 | 萨奇治疗股份有限公司 | 19-去甲c3,3-二取代的c21-n-吡唑基类固醇及其使用方法 |
| JOP20200195A1 (ar) * | 2014-09-08 | 2017-06-16 | Sage Therapeutics Inc | سترويدات وتركيبات نشطة عصبياً، واستخداماتها |
| EP3206493B1 (en) * | 2014-10-16 | 2020-05-06 | Sage Therapeutics, Inc. | Compositions and methods for treating cns disorders |
| EP3426257A4 (en) * | 2016-03-08 | 2019-11-13 | Sage Therapeutics, Inc. | NEUROACTIVE STEROIDS, COMPOSITIONS AND USES THEREOF |
| EP3504189A1 (en) * | 2016-08-23 | 2019-07-03 | Sage Therapeutics, Inc. | A crystalline 19-nor c3, 3-disubstituted c21-n-pyrazolyl steroid |
| JP2020533310A (ja) * | 2017-09-07 | 2020-11-19 | セージ セラピューティクス， インコーポレイテッド | 神経刺激性ステロイドおよびそれらの使用方法 |
-
2019
- 2019-06-12 SG SG11202012344RA patent/SG11202012344RA/en unknown
- 2019-06-12 WO PCT/US2019/036848 patent/WO2019241442A1/en unknown
- 2019-06-12 TW TW108120367A patent/TW202005653A/zh unknown
- 2019-06-12 AU AU2019287491A patent/AU2019287491A1/en active Pending
- 2019-06-12 JP JP2020569024A patent/JP2021527092A/ja active Pending
- 2019-06-12 CN CN201980051843.5A patent/CN112533611A/zh active Pending
- 2019-06-12 MA MA052894A patent/MA52894A/fr unknown
- 2019-06-12 US US17/251,475 patent/US20210338692A1/en active Pending
- 2019-06-12 CA CA3103421A patent/CA3103421A1/en active Pending
- 2019-06-12 CN CN202410051762.8A patent/CN117959309A/zh active Pending
- 2019-06-12 MX MX2020013557A patent/MX2020013557A/es unknown
- 2019-06-12 EP EP19737327.7A patent/EP3806863A1/en active Pending
- 2019-06-12 KR KR1020217000726A patent/KR20210021005A/ko unknown
- 2019-12-05 US US16/704,800 patent/US20200113917A1/en not_active Abandoned
-
2020
- 2020-12-09 IL IL279315A patent/IL279315A/en unknown
-
2022
- 2022-06-17 US US17/843,031 patent/US20220323462A1/en active Pending
-
2023
- 2023-12-05 JP JP2023205211A patent/JP2024028849A/ja active Pending
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