JPWO2019221838A5 - - Google Patents
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- Publication number
- JPWO2019221838A5 JPWO2019221838A5 JP2020564455A JP2020564455A JPWO2019221838A5 JP WO2019221838 A5 JPWO2019221838 A5 JP WO2019221838A5 JP 2020564455 A JP2020564455 A JP 2020564455A JP 2020564455 A JP2020564455 A JP 2020564455A JP WO2019221838 A5 JPWO2019221838 A5 JP WO2019221838A5
- Authority
- JP
- Japan
- Prior art keywords
- cross
- linking agent
- weight
- monomer mixture
- water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003431 cross linking reagent Substances 0.000 claims 38
- 239000000178 monomer Substances 0.000 claims 32
- 239000000203 mixture Substances 0.000 claims 29
- 239000001257 hydrogen Substances 0.000 claims 11
- 229910052739 hydrogen Inorganic materials 0.000 claims 11
- -1 cyclic lactams Chemical class 0.000 claims 9
- 229910052760 oxygen Inorganic materials 0.000 claims 8
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 claims 6
- 125000000217 alkyl group Chemical group 0.000 claims 6
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 6
- 239000004971 Cross linker Substances 0.000 claims 5
- KPUWHANPEXNPJT-UHFFFAOYSA-N disiloxane Chemical class [SiH3]O[SiH3] KPUWHANPEXNPJT-UHFFFAOYSA-N 0.000 claims 5
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 5
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 5
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical group CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims 4
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims 4
- 150000002431 hydrogen Chemical class 0.000 claims 4
- CYRMSUTZVYGINF-UHFFFAOYSA-N trichlorofluoromethane Chemical compound FC(Cl)(Cl)Cl CYRMSUTZVYGINF-UHFFFAOYSA-N 0.000 claims 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 4
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims 3
- LYCAIKOWRPUZTN-UHFFFAOYSA-N ethylene glycol Natural products OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims 3
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 claims 3
- 238000000034 method Methods 0.000 claims 3
- 239000001301 oxygen Substances 0.000 claims 3
- 230000035699 permeability Effects 0.000 claims 3
- OCAAZRFBJBEVPS-UHFFFAOYSA-N prop-2-enyl carbamate Chemical compound NC(=O)OCC=C OCAAZRFBJBEVPS-UHFFFAOYSA-N 0.000 claims 3
- LVLANIHJQRZTPY-UHFFFAOYSA-N vinyl carbamate Chemical compound NC(=O)OC=C LVLANIHJQRZTPY-UHFFFAOYSA-N 0.000 claims 3
- BESKSSIEODQWBP-UHFFFAOYSA-N 3-tris(trimethylsilyloxy)silylpropyl 2-methylprop-2-enoate Chemical compound CC(=C)C(=O)OCCC[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C BESKSSIEODQWBP-UHFFFAOYSA-N 0.000 claims 2
- PIGFYZPCRLYGLF-UHFFFAOYSA-N Aluminum nitride Chemical group [Al]#N PIGFYZPCRLYGLF-UHFFFAOYSA-N 0.000 claims 2
- KXDHJXZQYSOELW-UHFFFAOYSA-N Carbamic acid Chemical group NC(O)=O KXDHJXZQYSOELW-UHFFFAOYSA-N 0.000 claims 2
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical group FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 claims 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 2
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 claims 2
- 239000007983 Tris buffer Substances 0.000 claims 2
- 125000003342 alkenyl group Chemical group 0.000 claims 2
- 125000003118 aryl group Chemical group 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 claims 2
- 125000000753 cycloalkyl group Chemical group 0.000 claims 2
- 125000001033 ether group Chemical group 0.000 claims 2
- 239000011737 fluorine Chemical group 0.000 claims 2
- 229910052731 fluorine Inorganic materials 0.000 claims 2
- 125000000262 haloalkenyl group Chemical group 0.000 claims 2
- 125000001188 haloalkyl group Chemical group 0.000 claims 2
- 125000000592 heterocycloalkyl group Chemical group 0.000 claims 2
- 150000003951 lactams Chemical class 0.000 claims 2
- 125000005647 linker group Chemical group 0.000 claims 2
- 125000001181 organosilyl group Chemical group [SiH3]* 0.000 claims 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 2
- 229910052710 silicon Inorganic materials 0.000 claims 2
- 239000010703 silicon Substances 0.000 claims 2
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 claims 2
- JWYVGKFDLWWQJX-UHFFFAOYSA-N 1-ethenylazepan-2-one Chemical compound C=CN1CCCCCC1=O JWYVGKFDLWWQJX-UHFFFAOYSA-N 0.000 claims 1
- PBGPBHYPCGDFEZ-UHFFFAOYSA-N 1-ethenylpiperidin-2-one Chemical compound C=CN1CCCCC1=O PBGPBHYPCGDFEZ-UHFFFAOYSA-N 0.000 claims 1
- KXDHJXZQYSOELW-UHFFFAOYSA-M Carbamate Chemical compound NC([O-])=O KXDHJXZQYSOELW-UHFFFAOYSA-M 0.000 claims 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 claims 1
- WOBHKFSMXKNTIM-UHFFFAOYSA-N Hydroxyethyl methacrylate Chemical compound CC(=C)C(=O)OCCO WOBHKFSMXKNTIM-UHFFFAOYSA-N 0.000 claims 1
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 claims 1
- YPMNWQTVWVHXIQ-UHFFFAOYSA-N [methyl-bis(trimethylsilyloxy)silyl]methyl 2-methylprop-2-enoate Chemical compound CC(=C)C(=O)OC[Si](C)(O[Si](C)(C)C)O[Si](C)(C)C YPMNWQTVWVHXIQ-UHFFFAOYSA-N 0.000 claims 1
- 239000002981 blocking agent Substances 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 238000001035 drying Methods 0.000 claims 1
- FXPHJTKVWZVEGA-UHFFFAOYSA-N ethenyl hydrogen carbonate Chemical compound OC(=O)OC=C FXPHJTKVWZVEGA-UHFFFAOYSA-N 0.000 claims 1
- ILHMPZFVDISGNP-UHFFFAOYSA-N ethenyl n-[3-tris(trimethylsilyloxy)silylpropyl]carbamate Chemical compound C[Si](C)(C)O[Si](O[Si](C)(C)C)(O[Si](C)(C)C)CCCNC(=O)OC=C ILHMPZFVDISGNP-UHFFFAOYSA-N 0.000 claims 1
- 239000000017 hydrogel Substances 0.000 claims 1
- ZFSLODLOARCGLH-UHFFFAOYSA-N isocyanuric acid Chemical compound OC1=NC(O)=NC(O)=N1 ZFSLODLOARCGLH-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862671569P | 2018-05-15 | 2018-05-15 | |
| US62/671,569 | 2018-05-15 | ||
| PCT/US2019/025956 WO2019221838A1 (en) | 2018-05-15 | 2019-04-05 | Water extractable ophthalmic devices |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2021523419A JP2021523419A (ja) | 2021-09-02 |
| JP2021523419A5 JP2021523419A5 (https=) | 2022-02-21 |
| JPWO2019221838A5 true JPWO2019221838A5 (https=) | 2022-02-21 |
| JP7282105B2 JP7282105B2 (ja) | 2023-05-26 |
Family
ID=66248711
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020564455A Active JP7282105B2 (ja) | 2018-05-15 | 2019-04-05 | 水抽出可能な眼科用デバイス |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US11345773B2 (https=) |
| EP (1) | EP3794388A1 (https=) |
| JP (1) | JP7282105B2 (https=) |
| KR (1) | KR102759003B1 (https=) |
| CN (1) | CN112352170B (https=) |
| CA (1) | CA3097124A1 (https=) |
| WO (1) | WO2019221838A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2726602A1 (es) * | 2018-04-06 | 2019-10-08 | Consejo Superior Investigacion | Hidrogeles basados en vinil-caprolactama |
| WO2020009747A1 (en) * | 2018-07-03 | 2020-01-09 | Bausch & Lomb Incorporated | Water extractable ophthalmic devices |
| TWI685545B (zh) | 2018-11-30 | 2020-02-21 | 晶碩光學股份有限公司 | 矽水膠組成物、矽水膠鏡片、以及矽水膠鏡片的製造方法 |
Family Cites Families (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL285986A (https=) | 1961-12-27 | |||
| NL128305C (https=) | 1963-09-11 | |||
| GB1430077A (en) * | 1972-07-31 | 1976-03-31 | Ici Ltd | Silicone elastomers |
| US4113224A (en) | 1975-04-08 | 1978-09-12 | Bausch & Lomb Incorporated | Apparatus for forming optical lenses |
| US4197266A (en) | 1974-05-06 | 1980-04-08 | Bausch & Lomb Incorporated | Method for forming optical lenses |
| US4555732A (en) | 1984-03-22 | 1985-11-26 | Xerox Corporation | Image sensor correction system |
| JPH0670159B2 (ja) * | 1986-02-12 | 1994-09-07 | 大日本インキ化学工業株式会社 | 硬化性樹脂組成物 |
| US4910277A (en) | 1988-02-09 | 1990-03-20 | Bambury Ronald E | Hydrophilic oxygen permeable polymers |
| US5070215A (en) | 1989-05-02 | 1991-12-03 | Bausch & Lomb Incorporated | Novel vinyl carbonate and vinyl carbamate contact lens material monomers |
| US5271875A (en) | 1991-09-12 | 1993-12-21 | Bausch & Lomb Incorporated | Method for molding lenses |
| US5310779A (en) * | 1991-11-05 | 1994-05-10 | Bausch & Lomb Incorporated | UV curable crosslinking agents useful in copolymerization |
| MY108731A (en) * | 1992-04-16 | 1996-11-30 | Akzo Nv | Aqueous coating compositions |
| US6020445A (en) | 1997-10-09 | 2000-02-01 | Johnson & Johnson Vision Products, Inc. | Silicone hydrogel polymers |
| US5998498A (en) | 1998-03-02 | 1999-12-07 | Johnson & Johnson Vision Products, Inc. | Soft contact lenses |
| ES2389811T3 (es) * | 2000-06-28 | 2012-10-31 | Prana Biotechnology Limited | Oligómeros de amiloide beta para uso en el tratamiento, el alivio o la prevención de la enfermedad de Alzheimer |
| AU2001297967B2 (en) * | 2001-04-27 | 2006-01-05 | Bausch & Lomb Incorporated | Iris pattern recognition and alignment |
| JP4059051B2 (ja) * | 2002-06-14 | 2008-03-12 | Ｊｓｒ株式会社 | 環状オレフィン系共重合体およびその製造方法 |
| JP2008020918A (ja) * | 2006-06-15 | 2008-01-31 | Coopervision Internatl Holding Co Lp | 湿潤性シリコーンヒドロゲルコンタクトレンズ及び関連組成物及び方法 |
| US8231218B2 (en) | 2006-06-15 | 2012-07-31 | Coopervision International Holding Company, Lp | Wettable silicone hydrogel contact lenses and related compositions and methods |
| GB0623299D0 (en) | 2006-11-22 | 2007-01-03 | Sauflon Cl Ltd | Contact lens |
| EP3424965B1 (en) * | 2007-07-10 | 2020-05-13 | Bausch & Lomb Incorporated | Crosslink agents and its use |
| US8053489B2 (en) | 2007-07-20 | 2011-11-08 | Bausch & Lomb Incorporated | Crosslink agents and dual radical cure polymer |
| US7994356B2 (en) | 2009-07-09 | 2011-08-09 | Bausch & Lomb Incorporated | Mono ethylenically unsaturated polycarbosiloxane monomers |
| PL2452212T3 (pl) | 2009-07-09 | 2015-08-31 | Bausch & Lomb | Monoetylenowo nienasycone zdolne do polimeryzacji grupy zawierające monomery polikarboksylanów |
| US8827447B2 (en) * | 2009-07-09 | 2014-09-09 | Bausch & Lomb Incorporated | Mono ethylenically unsaturated polymerizable group containing polycarbosiloxane monomers |
| US9039174B2 (en) | 2009-07-09 | 2015-05-26 | Bausch & Lomb Incorporated | Ethylenically unsaturated polymerizable groups comprising polycarbosiloxane monomers |
| US7915323B2 (en) | 2009-07-09 | 2011-03-29 | Bausch & Lamb Incorporated | Mono ethylenically unsaturated polycarbosiloxane monomers |
| US8672475B2 (en) | 2009-10-01 | 2014-03-18 | Coopervision International Holding Company, LLC | Silicone hydrogel contact lenses and methods of making silicone hydrogel contact lenses |
| GB0917806D0 (en) | 2009-10-12 | 2009-11-25 | Sauflon Cl Ltd | Fluorinated silicone hydrogels |
| EP2386600B1 (de) * | 2010-04-15 | 2013-06-19 | LANXESS Deutschland GmbH | Isocyanatgruppen-enthaltende Vernetzer für Nitrilkautschuke |
| IN2014DN02047A (https=) * | 2011-10-03 | 2015-05-15 | Synthes Gmbh | |
| US8937111B2 (en) | 2011-12-23 | 2015-01-20 | Johnson & Johnson Vision Care, Inc. | Silicone hydrogels comprising desirable water content and oxygen permeability |
| US9156934B2 (en) | 2011-12-23 | 2015-10-13 | Johnson & Johnson Vision Care, Inc. | Silicone hydrogels comprising n-vinyl amides and hydroxyalkyl (meth)acrylates or (meth)acrylamides |
| US8937110B2 (en) | 2011-12-23 | 2015-01-20 | Johnson & Johnson Vision Care, Inc. | Silicone hydrogels having a structure formed via controlled reaction kinetics |
| US20130313733A1 (en) | 2012-05-25 | 2013-11-28 | Ivan Nunez | Method of making a fully polymerized uv blocking silicone hydrogel lens |
| EP2856218B9 (en) | 2012-05-25 | 2016-11-30 | Bausch & Lomb Incorporated | Fully polymerized uv blocking silicone hydrogel lens |
| US9075187B2 (en) | 2012-05-25 | 2015-07-07 | Bausch & Lomb Incorporated | Fully polymerized UV blocking silicone hydrogel lens |
| US8807745B2 (en) | 2012-05-25 | 2014-08-19 | Bausch & Lomb Incorporated | Fully polymerized UV blocking silicone hydrogel lens |
| US8967799B2 (en) | 2012-12-20 | 2015-03-03 | Bausch & Lomb Incorporated | Method of preparing water extractable silicon-containing biomedical devices |
| US20160001541A1 (en) * | 2014-07-03 | 2016-01-07 | Wacker Chemical Corporation | Preparation of Multilayer Structural Composites Prepared Using Consolidation Liners Of High Parting Force |
| JP6615349B2 (ja) * | 2015-12-15 | 2019-12-04 | ノバルティス アーゲー | 両親媒性分枝鎖状ポリジオルガノシロキサンマクロマー |
-
2019
- 2019-04-05 KR KR1020207036126A patent/KR102759003B1/ko active Active
- 2019-04-05 EP EP19718979.8A patent/EP3794388A1/en active Pending
- 2019-04-05 CA CA3097124A patent/CA3097124A1/en active Pending
- 2019-04-05 CN CN201980029402.5A patent/CN112352170B/zh active Active
- 2019-04-05 US US16/376,136 patent/US11345773B2/en active Active
- 2019-04-05 WO PCT/US2019/025956 patent/WO2019221838A1/en not_active Ceased
- 2019-04-05 JP JP2020564455A patent/JP7282105B2/ja active Active
-
2022
- 2022-04-26 US US17/729,181 patent/US11897985B2/en active Active
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