JPWO2020009747A5 - - Google Patents
Download PDFInfo
- Publication number
- JPWO2020009747A5 JPWO2020009747A5 JP2020573441A JP2020573441A JPWO2020009747A5 JP WO2020009747 A5 JPWO2020009747 A5 JP WO2020009747A5 JP 2020573441 A JP2020573441 A JP 2020573441A JP 2020573441 A JP2020573441 A JP 2020573441A JP WO2020009747 A5 JPWO2020009747 A5 JP WO2020009747A5
- Authority
- JP
- Japan
- Prior art keywords
- cross
- linking agent
- weight
- monomer mixture
- water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003431 cross linking reagent Substances 0.000 claims description 105
- 239000000203 mixture Substances 0.000 claims description 72
- 239000000178 monomer Substances 0.000 claims description 64
- 125000000217 alkyl group Chemical group 0.000 claims description 27
- 229920001400 block copolymer Polymers 0.000 claims description 24
- -1 C1- C12alkyl Chemical group 0.000 claims description 22
- 239000001257 hydrogen Substances 0.000 claims description 22
- 229910052739 hydrogen Inorganic materials 0.000 claims description 22
- 238000000034 method Methods 0.000 claims description 21
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 16
- 239000004971 Cross linker Substances 0.000 claims description 14
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims description 14
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 claims description 13
- 229910052760 oxygen Inorganic materials 0.000 claims description 13
- KPUWHANPEXNPJT-UHFFFAOYSA-N disiloxane Chemical class [SiH3]O[SiH3] KPUWHANPEXNPJT-UHFFFAOYSA-N 0.000 claims description 12
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 9
- LYCAIKOWRPUZTN-UHFFFAOYSA-N ethylene glycol Natural products OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims description 9
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 claims description 9
- 239000001301 oxygen Substances 0.000 claims description 9
- 230000035699 permeability Effects 0.000 claims description 9
- OCAAZRFBJBEVPS-UHFFFAOYSA-N prop-2-enyl carbamate Chemical compound NC(=O)OCC=C OCAAZRFBJBEVPS-UHFFFAOYSA-N 0.000 claims description 9
- LVLANIHJQRZTPY-UHFFFAOYSA-N vinyl carbamate Chemical compound NC(=O)OC=C LVLANIHJQRZTPY-UHFFFAOYSA-N 0.000 claims description 9
- 125000005353 silylalkyl group Chemical group 0.000 claims description 8
- 125000006710 (C2-C12) alkenyl group Chemical group 0.000 claims description 6
- 125000000262 haloalkenyl group Chemical group 0.000 claims description 6
- 125000001188 haloalkyl group Chemical group 0.000 claims description 6
- 125000000592 heterocycloalkyl group Chemical group 0.000 claims description 6
- 150000002431 hydrogen Chemical group 0.000 claims description 6
- 125000005647 linker group Chemical group 0.000 claims description 6
- WOBHKFSMXKNTIM-UHFFFAOYSA-N Hydroxyethyl methacrylate Chemical compound CC(=C)C(=O)OCCO WOBHKFSMXKNTIM-UHFFFAOYSA-N 0.000 claims description 5
- 239000003795 chemical substances by application Substances 0.000 claims description 5
- 239000002981 blocking agent Substances 0.000 claims description 4
- 238000006243 chemical reaction Methods 0.000 claims description 4
- 150000003951 lactams Chemical class 0.000 claims description 4
- KXDHJXZQYSOELW-UHFFFAOYSA-M Carbamate Chemical compound NC([O-])=O KXDHJXZQYSOELW-UHFFFAOYSA-M 0.000 claims description 3
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims description 3
- 125000000753 cycloalkyl group Chemical group 0.000 claims description 3
- FXPHJTKVWZVEGA-UHFFFAOYSA-N ethenyl hydrogen carbonate Chemical compound OC(=O)OC=C FXPHJTKVWZVEGA-UHFFFAOYSA-N 0.000 claims description 3
- ZFSLODLOARCGLH-UHFFFAOYSA-N isocyanuric acid Chemical compound OC1=NC(O)=NC(O)=N1 ZFSLODLOARCGLH-UHFFFAOYSA-N 0.000 claims description 3
- SNOOUWRIMMFWNE-UHFFFAOYSA-M sodium;6-[(3,4,5-trimethoxybenzoyl)amino]hexanoate Chemical compound [Na+].COC1=CC(C(=O)NCCCCCC([O-])=O)=CC(OC)=C1OC SNOOUWRIMMFWNE-UHFFFAOYSA-M 0.000 claims description 3
- GBXQPDCOMJJCMJ-UHFFFAOYSA-M trimethyl-[6-(trimethylazaniumyl)hexyl]azanium;bromide Chemical compound [Br-].C[N+](C)(C)CCCCCC[N+](C)(C)C GBXQPDCOMJJCMJ-UHFFFAOYSA-M 0.000 claims description 3
- 238000003809 water extraction Methods 0.000 claims description 3
- 238000001035 drying Methods 0.000 claims description 2
- 238000006116 polymerization reaction Methods 0.000 claims description 2
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical compound [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 description 8
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 6
- 238000001723 curing Methods 0.000 description 3
- 239000003085 diluting agent Substances 0.000 description 3
- JWYVGKFDLWWQJX-UHFFFAOYSA-N 1-ethenylazepan-2-one Chemical compound C=CN1CCCCCC1=O JWYVGKFDLWWQJX-UHFFFAOYSA-N 0.000 description 2
- PBGPBHYPCGDFEZ-UHFFFAOYSA-N 1-ethenylpiperidin-2-one Chemical compound C=CN1CCCCC1=O PBGPBHYPCGDFEZ-UHFFFAOYSA-N 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 description 2
- KGBXLFKZBHKPEV-UHFFFAOYSA-N boric acid Chemical class OB(O)O KGBXLFKZBHKPEV-UHFFFAOYSA-N 0.000 description 2
- 239000000017 hydrogel Substances 0.000 description 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 description 2
- 239000003732 agents acting on the eye Substances 0.000 description 1
- 238000011416 infrared curing Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 229940125702 ophthalmic agent Drugs 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 229920001187 thermosetting polymer Polymers 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862693746P | 2018-07-03 | 2018-07-03 | |
| US62/693,746 | 2018-07-03 | ||
| PCT/US2019/032819 WO2020009747A1 (en) | 2018-07-03 | 2019-05-17 | Water extractable ophthalmic devices |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2021529353A JP2021529353A (ja) | 2021-10-28 |
| JP2021529353A5 JP2021529353A5 (https=) | 2022-04-06 |
| JPWO2020009747A5 true JPWO2020009747A5 (https=) | 2022-04-06 |
| JP7368397B2 JP7368397B2 (ja) | 2023-10-24 |
Family
ID=66776887
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020573441A Active JP7368397B2 (ja) | 2018-07-03 | 2019-05-17 | 水抽出可能な眼科用デバイス |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US11022722B2 (https=) |
| EP (1) | EP3818401B1 (https=) |
| JP (1) | JP7368397B2 (https=) |
| KR (1) | KR102749934B1 (https=) |
| CN (1) | CN112513681B (https=) |
| CA (1) | CA3104247A1 (https=) |
| ES (1) | ES3005558T3 (https=) |
| WO (1) | WO2020009747A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2726602A1 (es) * | 2018-04-06 | 2019-10-08 | Consejo Superior Investigacion | Hidrogeles basados en vinil-caprolactama |
| TWI685545B (zh) * | 2018-11-30 | 2020-02-21 | 晶碩光學股份有限公司 | 矽水膠組成物、矽水膠鏡片、以及矽水膠鏡片的製造方法 |
| MX2022011568A (es) * | 2020-03-19 | 2022-10-18 | Alcon Inc | Materiales de insercion de siloxano con alto indice de refraccion para lentes de contacto embebidas. |
| KR20220124925A (ko) | 2021-03-04 | 2022-09-14 | 엘지전자 주식회사 | 냉장고 |
| TWI865184B (zh) * | 2023-01-09 | 2024-12-01 | 視陽光學股份有限公司 | 用於隱形眼鏡的組成物與隱形眼鏡 |
Family Cites Families (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL285986A (https=) | 1961-12-27 | |||
| NL128305C (https=) | 1963-09-11 | |||
| US4113224A (en) | 1975-04-08 | 1978-09-12 | Bausch & Lomb Incorporated | Apparatus for forming optical lenses |
| US4197266A (en) | 1974-05-06 | 1980-04-08 | Bausch & Lomb Incorporated | Method for forming optical lenses |
| US4208506A (en) | 1977-07-25 | 1980-06-17 | Bausch & Lomb Incorporated | Polyparaffinsiloxane shaped article for use in biomedical applications |
| US4228269A (en) * | 1978-06-08 | 1980-10-14 | Wesley-Jessen Inc. | Contact lenses of high gas permeability |
| US4195030A (en) | 1979-01-10 | 1980-03-25 | Bausch & Lomb Incorporated | Preparation of monomeric organosilicon esters |
| US4355147A (en) | 1981-02-26 | 1982-10-19 | Bausch & Lomb Incorporated | Polysiloxane with polycyclic modifier composition and biomedical devices |
| US4327203A (en) | 1981-02-26 | 1982-04-27 | Bausch & Lomb Incorporated | Polysiloxane with cycloalkyl modifier composition and biomedical devices |
| US4555732A (en) | 1984-03-22 | 1985-11-26 | Xerox Corporation | Image sensor correction system |
| US4910277A (en) | 1988-02-09 | 1990-03-20 | Bambury Ronald E | Hydrophilic oxygen permeable polymers |
| US5070215A (en) | 1989-05-02 | 1991-12-03 | Bausch & Lomb Incorporated | Novel vinyl carbonate and vinyl carbamate contact lens material monomers |
| US5271875A (en) | 1991-09-12 | 1993-12-21 | Bausch & Lomb Incorporated | Method for molding lenses |
| US5310779A (en) * | 1991-11-05 | 1994-05-10 | Bausch & Lomb Incorporated | UV curable crosslinking agents useful in copolymerization |
| US6020445A (en) | 1997-10-09 | 2000-02-01 | Johnson & Johnson Vision Products, Inc. | Silicone hydrogel polymers |
| US5998498A (en) * | 1998-03-02 | 1999-12-07 | Johnson & Johnson Vision Products, Inc. | Soft contact lenses |
| JPH11249084A (ja) * | 1998-03-06 | 1999-09-17 | Kuraray Co Ltd | 眼用レンズ材料およびその製造方法 |
| US6244707B1 (en) * | 1998-07-21 | 2001-06-12 | Wesley Jessen Corporation | UV blocking lenses and material containing benzotriazoles and benzophenones |
| US6861123B2 (en) * | 2000-12-01 | 2005-03-01 | Johnson & Johnson Vision Care, Inc. | Silicone hydrogel contact lens |
| AU2001297967B2 (en) * | 2001-04-27 | 2006-01-05 | Bausch & Lomb Incorporated | Iris pattern recognition and alignment |
| US8153344B2 (en) * | 2004-07-16 | 2012-04-10 | Ppg Industries Ohio, Inc. | Methods for producing photosensitive microparticles, aqueous compositions thereof and articles prepared therewith |
| MX2007007804A (es) | 2004-12-29 | 2007-09-14 | Bausch & Lomb | Prepolimeros de polisiloxano para dispositivos biomedicos. |
| BRPI0615146B1 (pt) * | 2005-08-09 | 2018-04-03 | Coopervision International Holding Company, Lp | Composições e métodos para a produção de lentes de contato de silicone hidrogel |
| JP2008020918A (ja) | 2006-06-15 | 2008-01-31 | Coopervision Internatl Holding Co Lp | 湿潤性シリコーンヒドロゲルコンタクトレンズ及び関連組成物及び方法 |
| EP3424965B1 (en) * | 2007-07-10 | 2020-05-13 | Bausch & Lomb Incorporated | Crosslink agents and its use |
| US8138290B2 (en) * | 2008-01-25 | 2012-03-20 | Bausch & Lomb Incorporated | High water content ophthalmic devices |
| CN101482625B (zh) * | 2009-02-13 | 2010-09-29 | 广州科甫眼镜有限公司 | 含透明质酸钠的软性亲水接触镜及其制备方法 |
| US20100315588A1 (en) * | 2009-06-16 | 2010-12-16 | Bausch & Lomb Incorporated | Biomedical devices |
| US9039174B2 (en) | 2009-07-09 | 2015-05-26 | Bausch & Lomb Incorporated | Ethylenically unsaturated polymerizable groups comprising polycarbosiloxane monomers |
| PL2452212T3 (pl) * | 2009-07-09 | 2015-08-31 | Bausch & Lomb | Monoetylenowo nienasycone zdolne do polimeryzacji grupy zawierające monomery polikarboksylanów |
| US7915323B2 (en) | 2009-07-09 | 2011-03-29 | Bausch & Lamb Incorporated | Mono ethylenically unsaturated polycarbosiloxane monomers |
| US8672475B2 (en) * | 2009-10-01 | 2014-03-18 | Coopervision International Holding Company, LLC | Silicone hydrogel contact lenses and methods of making silicone hydrogel contact lenses |
| KR101528997B1 (ko) * | 2011-02-28 | 2015-06-15 | 쿠퍼비젼 인터내셔날 홀딩 캄파니, 엘피 | 치수 안정한 실리콘 히드로겔 콘택트 렌즈 |
| HUE051241T2 (hu) * | 2011-02-28 | 2021-03-01 | Coopervision Int Ltd | Szilikon hidrogél kontaktlencsék |
| WO2012128752A1 (en) * | 2011-03-21 | 2012-09-27 | Momentive Performance Materials Inc. | Siloxane monomers containing hydrolysis resistance carbosiloxane linkage, process for their preparation and thin films containing the same for contact lens application |
| US20120283381A1 (en) * | 2011-05-04 | 2012-11-08 | Ryuta Tamiya | Macroinitiator containing hydrophobic segment |
| US9156934B2 (en) * | 2011-12-23 | 2015-10-13 | Johnson & Johnson Vision Care, Inc. | Silicone hydrogels comprising n-vinyl amides and hydroxyalkyl (meth)acrylates or (meth)acrylamides |
| US8937111B2 (en) * | 2011-12-23 | 2015-01-20 | Johnson & Johnson Vision Care, Inc. | Silicone hydrogels comprising desirable water content and oxygen permeability |
| US8967799B2 (en) | 2012-12-20 | 2015-03-03 | Bausch & Lomb Incorporated | Method of preparing water extractable silicon-containing biomedical devices |
| KR20140111064A (ko) * | 2013-02-27 | 2014-09-18 | 에스케이이노베이션 주식회사 | 광학필름 |
| US9389336B2 (en) * | 2013-08-02 | 2016-07-12 | Bausch & Lomb Incorporated | Hydrogel monomer mix containing added water |
| WO2015164630A1 (en) * | 2014-04-25 | 2015-10-29 | Novartis Ag | Carbosiloxane vinylic monomers |
| MY197430A (en) * | 2015-12-15 | 2023-06-17 | Alcon Inc | Hydrophilized polydiorganosiloxane vinylic crosslinkers and uses thereof |
| US10676575B2 (en) * | 2016-10-06 | 2020-06-09 | Johnson & Johnson Vision Care, Inc. | Tri-block prepolymers and their use in silicone hydrogels |
| KR102759003B1 (ko) * | 2018-05-15 | 2025-01-23 | 보오슈 앤드 롬 인코포레이팃드 | 수 추출 가능한 안과용 디바이스 |
-
2019
- 2019-05-17 WO PCT/US2019/032819 patent/WO2020009747A1/en not_active Ceased
- 2019-05-17 JP JP2020573441A patent/JP7368397B2/ja active Active
- 2019-05-17 CA CA3104247A patent/CA3104247A1/en active Pending
- 2019-05-17 CN CN201980044304.9A patent/CN112513681B/zh active Active
- 2019-05-17 KR KR1020217001437A patent/KR102749934B1/ko active Active
- 2019-05-17 US US16/415,281 patent/US11022722B2/en active Active
- 2019-05-17 EP EP19729122.2A patent/EP3818401B1/en active Active
- 2019-05-17 ES ES19729122T patent/ES3005558T3/es active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP4493745B2 (ja) | ソフトコンタクトレンズ | |
| JP7014185B2 (ja) | コンタクトレンズ用モノマー組成物、コンタクトレンズ用重合体及びその製造方法、並びにコンタクトレンズ及びその製造方法 | |
| EP0675910B1 (en) | Novel macromonomers | |
| AU2012358819B2 (en) | Silicone hydrogels comprising desirable water content and oxygen permeability | |
| CN101687960B (zh) | 交联剂及双基固化聚合物 | |
| AU2012358909B2 (en) | Silicone hydrogels comprising N-vinyl amides and hydroxyalkyl (meth)acrylates or (meth)acrylamides | |
| US5314961A (en) | Silicone-containing polymers, compositions and improved oxygen permeable hydrophilic contact lenses | |
| AU755824B2 (en) | Silicone hydrogel polymers | |
| US5371147A (en) | Silicone-containing acrylic star polymers, block copolymers and macromonomers | |
| JP2021529353A5 (https=) | ||
| CA2860222A1 (en) | Ionic silicone hydrogels | |
| WO2015001811A1 (ja) | 親水性表面を有するシリコーン含有共重合体成形品を作製する方法及び親水性表面を有するシリコーンハイドロゲルコンタクトレンズ | |
| CA2859963A1 (en) | Silicone hydrogels having a structure formed via controlled reaction kinetics | |
| AU2005226782A1 (en) | Wettable hydrogels comprising acyclic polyamides | |
| IE901384L (en) | Novel vinyl carbonate and vinyl carbamate contect lens¹material monomers | |
| CA2859929A1 (en) | Silicone hydrogels formed from zero diluent reactive mixtures | |
| AU2004256111B2 (en) | Silicone hydrogels having consistent concentrations of multi-functional polysiloxanes | |
| JP7551059B2 (ja) | コンタクトレンズ用モノマー組成物、コンタクトレンズ用重合体及びその製造方法、並びにコンタクトレンズ及びその製造方法 | |
| IE890602L (en) | Polymers | |
| JP6907845B2 (ja) | コンタクトレンズ用モノマー組成物、コンタクトレンズ用重合体及びその製造方法、並びにコンタクトレンズ及びその製造方法 | |
| JPWO2020009747A5 (https=) | ||
| CN116209702A (zh) | 隐形眼镜材料及隐形眼镜镜片 | |
| KR102794585B1 (ko) | 콘택트 렌즈용 모노머 조성물 및 콘택트 렌즈용 중합체, 그리고 콘택트 렌즈 및 그 제조 방법 | |
| CN117546077B (zh) | 隐形眼镜及该隐形眼镜的制造方法 | |
| KR102715262B1 (ko) | 우수한 물성을 가지는 실리콘 하이드로겔 렌즈 |