JPWO2019151062A1 - 液体クロマトグラフ - Google Patents
液体クロマトグラフ Download PDFInfo
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- JPWO2019151062A1 JPWO2019151062A1 JP2019569038A JP2019569038A JPWO2019151062A1 JP WO2019151062 A1 JPWO2019151062 A1 JP WO2019151062A1 JP 2019569038 A JP2019569038 A JP 2019569038A JP 2019569038 A JP2019569038 A JP 2019569038A JP WO2019151062 A1 JPWO2019151062 A1 JP WO2019151062A1
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- plunger
- solvent
- pressurizing chamber
- pump
- suction passage
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- 239000007788 liquid Substances 0.000 title claims abstract description 54
- 239000002904 solvent Substances 0.000 claims abstract description 53
- 238000007599 discharging Methods 0.000 abstract description 2
- 230000033001 locomotion Effects 0.000 description 8
- 238000000926 separation method Methods 0.000 description 7
- 239000003638 chemical reducing agent Substances 0.000 description 4
- 230000000694 effects Effects 0.000 description 2
- 239000010419 fine particle Substances 0.000 description 2
- 241000220317 Rosa Species 0.000 description 1
- 238000002835 absorbance Methods 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 238000004904 shortening Methods 0.000 description 1
- 238000011144 upstream manufacturing Methods 0.000 description 1
Images
Classifications
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B49/00—Control, e.g. of pump delivery, or pump pressure of, or safety measures for, machines, pumps, or pumping installations, not otherwise provided for, or of interest apart from, groups F04B1/00 - F04B47/00
- F04B49/12—Control, e.g. of pump delivery, or pump pressure of, or safety measures for, machines, pumps, or pumping installations, not otherwise provided for, or of interest apart from, groups F04B1/00 - F04B47/00 by varying the length of stroke of the working members
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B13/00—Pumps specially modified to deliver fixed or variable measured quantities
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B15/00—Pumps adapted to handle specific fluids, e.g. by selection of specific materials for pumps or pump parts
- F04B15/02—Pumps adapted to handle specific fluids, e.g. by selection of specific materials for pumps or pump parts the fluids being viscous or non-homogeneous
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B49/00—Control, e.g. of pump delivery, or pump pressure of, or safety measures for, machines, pumps, or pumping installations, not otherwise provided for, or of interest apart from, groups F04B1/00 - F04B47/00
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B49/00—Control, e.g. of pump delivery, or pump pressure of, or safety measures for, machines, pumps, or pumping installations, not otherwise provided for, or of interest apart from, groups F04B1/00 - F04B47/00
- F04B49/06—Control using electricity
- F04B49/065—Control using electricity and making use of computers
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B49/00—Control, e.g. of pump delivery, or pump pressure of, or safety measures for, machines, pumps, or pumping installations, not otherwise provided for, or of interest apart from, groups F04B1/00 - F04B47/00
- F04B49/20—Control, e.g. of pump delivery, or pump pressure of, or safety measures for, machines, pumps, or pumping installations, not otherwise provided for, or of interest apart from, groups F04B1/00 - F04B47/00 by changing the driving speed
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B53/00—Component parts, details or accessories not provided for in, or of interest apart from, groups F04B1/00 - F04B23/00 or F04B39/00 - F04B47/00
- F04B53/02—Packing the free space between cylinders and pistons
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B53/00—Component parts, details or accessories not provided for in, or of interest apart from, groups F04B1/00 - F04B23/00 or F04B39/00 - F04B47/00
- F04B53/14—Pistons, piston-rods or piston-rod connections
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/28—Control of physical parameters of the fluid carrier
- G01N30/32—Control of physical parameters of the fluid carrier of pressure or speed
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B17/00—Pumps characterised by combination with, or adaptation to, specific driving engines or motors
- F04B17/03—Pumps characterised by combination with, or adaptation to, specific driving engines or motors driven by electric motors
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B23/00—Pumping installations or systems
- F04B23/04—Combinations of two or more pumps
- F04B23/06—Combinations of two or more pumps the pumps being all of reciprocating positive-displacement type
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N2030/022—Column chromatography characterised by the kind of separation mechanism
- G01N2030/027—Liquid chromatography
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/28—Control of physical parameters of the fluid carrier
- G01N30/32—Control of physical parameters of the fluid carrier of pressure or speed
- G01N2030/326—Control of physical parameters of the fluid carrier of pressure or speed pumps
Landscapes
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- General Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Computer Hardware Design (AREA)
- Details Of Reciprocating Pumps (AREA)
- Reciprocating Pumps (AREA)
- Control Of Positive-Displacement Pumps (AREA)
Abstract
Description
本発明は上記した実施例に限定されるものではなく、様々な変形例が含まれることはいうまでもない。
2 第一のプランジャ
3 第二のプランジャ
4 逆止弁
5 逆止弁
10 第一の吸入通路
11 第二の吐出通路
12 第一の加圧室
13 第二の加圧室
21 下死点
22 上死点
23 液残り部
24 連結通路
50 コントローラ
53 インジェクタ
54 分離カラム
55 検出器
60 圧力センサ
61 シール
62 シール
63 ばね
71 軸受
72 軸受
81 電磁弁
82 電磁弁
91 合流部
100 液体クロマトグラフ
101 第一のプランジャポンプ
102 第二のプランジャポンプ
103 第一の吐出通路
104 第二の吸入通路
105 圧力センサ
106 モータドライバ
107 電磁弁ドライバ
111 第一のポンプヘッド
112 第二のポンプヘッド
121 加圧室12の内面付近
211 第一の電動モータ
212 第二の電動モータ
221 減速装置
222 減速装置
231 直動装置
232 直動装置
511 溶媒
512 溶媒
Claims (3)
- 溶媒を吸引し吐出する送液ポンプを備えた液体クロマトグラフであって、
前記送液ポンプは、
吸引通路、加圧室、吐出通路が内部に形成されたポンプヘッドと、
プランジャと、
前記加圧室を封止するシールと、
を備え、
前記プランジャの下死点が、前記吸引通路よりも前記加圧室の上端側に配置されている液体クロマトグラフ。 - 溶媒を吸引し吐出する送液ポンプを備えた液体クロマトグラフであって、
前記送液ポンプは、
吸引通路、加圧室、吐出通路が内部に形成されたポンプヘッドと、
プランジャと、
前記加圧室を封止するシールと、
を備え、
前記プランジャの下死点が、プランジャの上面と吸引通路の加圧室の下端側面とが略同一になるように配置されている
液体クロマトグラフ。 - 請求項1または2に記載の液体クロマトグラフであって、
前記送液ポンプが、前記プランジャの駆動速度または溶媒の物性に応じて、前記プランジャの下死点を前記吸引通路の位置に対して相対的に変更するコントローラを備えた
液体クロマトグラフ。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2018016919 | 2018-02-02 | ||
JP2018016919 | 2018-02-02 | ||
PCT/JP2019/001963 WO2019151062A1 (ja) | 2018-02-02 | 2019-01-23 | 液体クロマトグラフ |
Publications (1)
Publication Number | Publication Date |
---|---|
JPWO2019151062A1 true JPWO2019151062A1 (ja) | 2021-01-28 |
Family
ID=67479188
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2019569038A Pending JPWO2019151062A1 (ja) | 2018-02-02 | 2019-01-23 | 液体クロマトグラフ |
Country Status (4)
Country | Link |
---|---|
US (1) | US20210116427A1 (ja) |
EP (1) | EP3748161A4 (ja) |
JP (1) | JPWO2019151062A1 (ja) |
WO (1) | WO2019151062A1 (ja) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112343785B (zh) * | 2020-11-03 | 2023-02-21 | 上海齐耀动力技术有限公司 | 一种互为控制阀的双联液压驱动往复泵 |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH05149242A (ja) * | 1991-11-25 | 1993-06-15 | Shimadzu Corp | 液体クロマトグラフのプランジヤポンプ |
JP2004150402A (ja) * | 2002-11-01 | 2004-05-27 | Hitachi High-Technologies Corp | 液体クロマトグラフ用ポンプ |
JP2007113439A (ja) * | 2005-10-19 | 2007-05-10 | Hitachi High-Technologies Corp | ポンプ装置 |
WO2011090188A1 (ja) * | 2010-01-25 | 2011-07-28 | 株式会社日立ハイテクノロジーズ | 液体クロマトグラフ、および液体クロマトグラフ用送液装置 |
JP2014228499A (ja) * | 2013-05-27 | 2014-12-08 | 株式会社日立ハイテクノロジーズ | 液体クロマトグラフ |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3785207T2 (de) * | 1987-09-26 | 1993-07-15 | Hewlett Packard Gmbh | Pumpvorrichtung zur abgabe von fluessigkeit bei hohem druck. |
JP3903827B2 (ja) | 2002-04-02 | 2007-04-11 | 株式会社島津製作所 | 直列ダブルシリンジ型送液ポンプと液体クロマトグラフ |
EP1680669A1 (en) * | 2003-11-05 | 2006-07-19 | Agilent Technologies, Inc. | Chromatography system |
JP5020767B2 (ja) * | 2007-10-05 | 2012-09-05 | ヤンマー株式会社 | サプライポンプ |
JP4934647B2 (ja) * | 2008-08-04 | 2012-05-16 | 株式会社日立ハイテクノロジーズ | 液体クロマトグラフ用ポンプ |
JP5338196B2 (ja) | 2008-08-21 | 2013-11-13 | 株式会社島津製作所 | プランジャポンプ |
JP5624825B2 (ja) * | 2010-07-29 | 2014-11-12 | 株式会社日立ハイテクノロジーズ | 液体クロマトグラフ用ポンプ、および液体クロマトグラフ |
-
2019
- 2019-01-23 US US16/966,969 patent/US20210116427A1/en not_active Abandoned
- 2019-01-23 EP EP19747222.8A patent/EP3748161A4/en not_active Withdrawn
- 2019-01-23 WO PCT/JP2019/001963 patent/WO2019151062A1/ja unknown
- 2019-01-23 JP JP2019569038A patent/JPWO2019151062A1/ja active Pending
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH05149242A (ja) * | 1991-11-25 | 1993-06-15 | Shimadzu Corp | 液体クロマトグラフのプランジヤポンプ |
JP2004150402A (ja) * | 2002-11-01 | 2004-05-27 | Hitachi High-Technologies Corp | 液体クロマトグラフ用ポンプ |
JP2007113439A (ja) * | 2005-10-19 | 2007-05-10 | Hitachi High-Technologies Corp | ポンプ装置 |
WO2011090188A1 (ja) * | 2010-01-25 | 2011-07-28 | 株式会社日立ハイテクノロジーズ | 液体クロマトグラフ、および液体クロマトグラフ用送液装置 |
JP2014228499A (ja) * | 2013-05-27 | 2014-12-08 | 株式会社日立ハイテクノロジーズ | 液体クロマトグラフ |
Also Published As
Publication number | Publication date |
---|---|
EP3748161A1 (en) | 2020-12-09 |
US20210116427A1 (en) | 2021-04-22 |
EP3748161A4 (en) | 2021-07-28 |
WO2019151062A1 (ja) | 2019-08-08 |
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