JPWO2019140188A5 - - Google Patents
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- JPWO2019140188A5 JPWO2019140188A5 JP2020538841A JP2020538841A JPWO2019140188A5 JP WO2019140188 A5 JPWO2019140188 A5 JP WO2019140188A5 JP 2020538841 A JP2020538841 A JP 2020538841A JP 2020538841 A JP2020538841 A JP 2020538841A JP WO2019140188 A5 JPWO2019140188 A5 JP WO2019140188A5
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- mmol
- compound
- disease
- aryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023143506A JP2023179445A (ja) | 2018-01-11 | 2023-09-05 | 疾患を治療するためのジヒドロセラミドデサチュラーゼ阻害剤 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862616253P | 2018-01-11 | 2018-01-11 | |
| US62/616,253 | 2018-01-11 | ||
| PCT/US2019/013193 WO2019140188A1 (en) | 2018-01-11 | 2019-01-11 | Inhibitors of dihydroceramide desaturase for treating disease |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023143506A Division JP2023179445A (ja) | 2018-01-11 | 2023-09-05 | 疾患を治療するためのジヒドロセラミドデサチュラーゼ阻害剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021510818A JP2021510818A (ja) | 2021-04-30 |
| JPWO2019140188A5 true JPWO2019140188A5 (es) | 2022-01-19 |
| JP7346425B2 JP7346425B2 (ja) | 2023-09-19 |
Family
ID=67219929
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020538841A Active JP7346425B2 (ja) | 2018-01-11 | 2019-01-11 | 疾患を治療するためのジヒドロセラミドデサチュラーゼ阻害剤 |
| JP2023143506A Pending JP2023179445A (ja) | 2018-01-11 | 2023-09-05 | 疾患を治療するためのジヒドロセラミドデサチュラーゼ阻害剤 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023143506A Pending JP2023179445A (ja) | 2018-01-11 | 2023-09-05 | 疾患を治療するためのジヒドロセラミドデサチュラーゼ阻害剤 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US11597715B2 (es) |
| EP (1) | EP3737361A4 (es) |
| JP (2) | JP7346425B2 (es) |
| KR (1) | KR20200119807A (es) |
| CN (1) | CN111787916B (es) |
| AU (1) | AU2019207887B2 (es) |
| CA (1) | CA3087729A1 (es) |
| WO (1) | WO2019140188A1 (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110099898B (zh) | 2016-10-24 | 2023-07-25 | 优曼尼蒂治疗公司 | 化合物及其用途 |
| US11135207B2 (en) * | 2016-12-13 | 2021-10-05 | Centaurus Therapeutics | Inhibitors of dihydroceramide desaturase for treating disease |
| EP3700934A4 (en) | 2017-10-24 | 2021-10-27 | Yumanity Therapeutics, Inc. | COMPOUNDS AND USES OF THESE COMPOUNDS |
| JP7346425B2 (ja) * | 2018-01-11 | 2023-09-19 | セントラス セラピューティクス | 疾患を治療するためのジヒドロセラミドデサチュラーゼ阻害剤 |
| CA3127791A1 (en) | 2019-01-24 | 2020-07-30 | Yumanity Therapeutics, Inc. | Compounds and uses thereof |
| US20230404972A1 (en) * | 2020-11-25 | 2023-12-21 | Lysosomal and Rare Disorders Research and Treatment Center, Inc. | Inhibition of caspase pathway as a treatment for lysosomal storage disorders |
| AU2022316995A1 (en) * | 2021-07-29 | 2024-03-14 | Shanghai Qilu Pharmaceutical Research And Development Centre Ltd. | Novel parp7 inhibitor and use thereof |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS62249945A (ja) | 1986-04-23 | 1987-10-30 | Fuji Photo Film Co Ltd | ハイドロキノン・モノエステル類の合成方法 |
| JP3476203B2 (ja) | 1997-02-24 | 2003-12-10 | ザイモジュネティックス インコーポレイテッド | カルシトニン擬似体 |
| FR2770131A1 (fr) | 1997-10-27 | 1999-04-30 | Union Pharma Scient Appl | Nouvelle association pharmaceutique a activite analgesique |
| US6375957B1 (en) * | 1997-12-22 | 2002-04-23 | Euro-Celtique, S.A. | Opioid agonist/opioid antagonist/acetaminophen combinations |
| US6894063B2 (en) | 2000-09-14 | 2005-05-17 | Schering Corporation | Substituted urea neuropeptide Y Y5 Receptor antagonists |
| ES2170030B1 (es) * | 2000-12-19 | 2003-11-16 | Consejo Superior Investigacion | Inhibidores de la dihidroceramida desaturasa. |
| AU2002355286B2 (en) | 2001-07-26 | 2005-10-13 | Schering Corporation | Substituted urea neuropeptide Y Y5 receptor antagonists |
| JP2006527212A (ja) | 2003-06-12 | 2006-11-30 | ノボ ノルディスク アクティーゼルスカブ | ホルモン感受性リパーゼの阻害剤として使用するための、置換ピペラジンカルバメート |
| CN1798735A (zh) | 2003-06-12 | 2006-07-05 | 诺沃挪第克公司 | 用作激素敏感性脂肪酶的抑制剂的1－芳基－4－(芳氧基羰基)－哌嗪衍生物 |
| US7129235B2 (en) | 2003-07-11 | 2006-10-31 | Abbott Laboratories | Amides useful for treating pain |
| EP1651638A1 (en) | 2003-08-08 | 2006-05-03 | Janssen Pharmaceutica N.V. | Pyridyl piperazinyl ureas |
| US7491720B2 (en) | 2004-10-29 | 2009-02-17 | Banyu Pharmaceutical Co., Ltd. | Aminopyridine derivatives having Aurora A selective inhibitory action |
| TW200633990A (en) | 2004-11-18 | 2006-10-01 | Takeda Pharmaceuticals Co | Amide compound |
| US8143257B2 (en) | 2004-11-23 | 2012-03-27 | Ptc Therapeutics, Inc. | Substituted phenols as active agents inhibiting VEGF production |
| US7598249B2 (en) | 2004-12-30 | 2009-10-06 | Janssen Pharmaceutica N.V. | Piperazinyl and piperidinyl ureas as modulators of fatty acid amide hydrolase |
| US7790726B2 (en) | 2005-08-16 | 2010-09-07 | Chemocentryx, Inc. | Monocyclic and bicyclic compounds and methods of use |
| WO2007149865A2 (en) | 2006-06-19 | 2007-12-27 | University Of Utah Research Foundation | Methods and compositions related to inhibition of ceramide synthesis |
| WO2008023720A1 (fr) | 2006-08-23 | 2008-02-28 | Astellas Pharma Inc. | COMPOSÉ D'URÉE OU SEL DUDIT COMPOSé |
| CA2711211A1 (en) * | 2008-01-03 | 2009-07-09 | Aft Pharmaceuticals Ltd. | Oral pharmaceutical suspension comprising paracetamol and ibuprofen |
| WO2010023512A1 (en) * | 2008-08-28 | 2010-03-04 | Matrix Laboratories Ltd. | Novel vanilloid receptor modulators, process for their preparation and pharmaceutical compositions containing them |
| FR2939135B1 (fr) * | 2008-12-02 | 2010-12-03 | Galderma Res & Dev | Nouveaux composes 4-(azacycloalkyl)-benzene-1,3-diol comme inhibiteurs de la tyrosinase, leur procede de preparation et leur utilisation en medecine humaine ainsi qu'en cosmetique |
| SG172974A1 (en) | 2009-01-28 | 2011-08-29 | Rigel Pharmaceuticals Inc | Carboxamide compounds and methods for using the same |
| JP2010195688A (ja) | 2009-02-23 | 2010-09-09 | Shionogi & Co Ltd | Ｎｐｙｙ５受容体拮抗作用を有するアミド及びウレア誘導体 |
| CA2785284A1 (en) | 2009-12-25 | 2011-06-30 | Tomoyuki Kamino | Novel aryl urea derivative |
| CN103172635B (zh) * | 2011-12-21 | 2016-04-27 | 上海医药工业研究院 | 哌嗪或哌啶类化合物、其盐、中间体、制备方法及应用 |
| WO2015038704A1 (en) * | 2013-09-11 | 2015-03-19 | The J. David Gladstone Institutes, A Testamentary Trust Established Under The Will Of J. David Gladstone | Compositions for preparing cardiomyocytes |
| BR112018076258A2 (pt) * | 2016-06-30 | 2019-03-26 | Basilea Pharm Int Ag | inibidores mitocondriais para o tratamento de distúrbios de proliferação |
| US11135207B2 (en) * | 2016-12-13 | 2021-10-05 | Centaurus Therapeutics | Inhibitors of dihydroceramide desaturase for treating disease |
| JP7346425B2 (ja) * | 2018-01-11 | 2023-09-19 | セントラス セラピューティクス | 疾患を治療するためのジヒドロセラミドデサチュラーゼ阻害剤 |
-
2019
- 2019-01-11 JP JP2020538841A patent/JP7346425B2/ja active Active
- 2019-01-11 WO PCT/US2019/013193 patent/WO2019140188A1/en unknown
- 2019-01-11 CA CA3087729A patent/CA3087729A1/en active Pending
- 2019-01-11 KR KR1020207023098A patent/KR20200119807A/ko not_active Application Discontinuation
- 2019-01-11 US US16/959,807 patent/US11597715B2/en active Active
- 2019-01-11 EP EP19738156.9A patent/EP3737361A4/en active Pending
- 2019-01-11 AU AU2019207887A patent/AU2019207887B2/en active Active
- 2019-01-11 CN CN201980015846.3A patent/CN111787916B/zh active Active
-
2023
- 2023-02-06 US US18/106,305 patent/US20230357187A1/en active Pending
- 2023-09-05 JP JP2023143506A patent/JP2023179445A/ja active Pending
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