JPWO2016129512A1 - 酸化型グルタチオンを含む徐放性肥料 - Google Patents
酸化型グルタチオンを含む徐放性肥料 Download PDFInfo
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- JPWO2016129512A1 JPWO2016129512A1 JP2016574774A JP2016574774A JPWO2016129512A1 JP WO2016129512 A1 JPWO2016129512 A1 JP WO2016129512A1 JP 2016574774 A JP2016574774 A JP 2016574774A JP 2016574774 A JP2016574774 A JP 2016574774A JP WO2016129512 A1 JPWO2016129512 A1 JP WO2016129512A1
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- sustained
- plant
- release
- oxidized glutathione
- release fertilizer
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Abstract
Description
(1)GSSGと、放出制御剤とを含む、徐放性肥料。
(2)GSSGと、放出制御剤と、水又は水溶性溶媒である溶媒との混合物を形成する工程と、
前記混合物からGSSGと放出制御剤とを含む粒子を形成する工程と
を含む前記(1)の徐放性肥料の製造方法。
酸化型グルタチオン(GSSG)とは、還元型グルタチオン(GSH、N−(N−γ−L−グルタミル−L−システイニル)グリシン)の2分子がジスルフィド結合を介して結合して形成される物質である。酸化型グルタチオン(GSSG)のフリー体は次式で表される。
2.徐放性肥料
2.1.徐放性肥料の形態
本発明の徐放性肥料は、GSSGが固形基材中に分散していることで徐放化された徐放固形製剤、GSSGを含む製剤(前記徐放固形製剤であってもよい)が更に被覆層によりコーティングされた徐放コーティング製剤、GSSGを含む粒子が分散相として乳化分散した徐放エマルジョン製剤等の各種の徐放性製剤の形態であることができる。本発明の徐放性肥料は徐放固形製剤の形態であることが好ましい。本発明の徐放性肥料の徐放固形製剤の形態には、被覆層によりコーティングされた形態も包含される。
2.2.放出制御剤及びその他の成分
本発明において放出制御剤とはGSSGに徐放性を付与する作用を有する物質を指し、前記各種の徐放性製剤の形態に応じて適宜選択される。例えば、徐放固形製剤においては、固形基材の少なくとも1成分として放出制御剤を用いればよい。徐放コーティング製剤においては、被覆層を構成する少なくとも1成分として放出制御剤を用いればよい。徐放エマルジョン製剤においては、分散相に含まれる成分や、分散相と連続相との界面に含まれる成分、連続相に含まれる成分等のうちの少なくとも1成分として放出制御剤を用いればよい。
2.3.徐放性肥料の組成
本発明の徐放性肥料における各成分の組成は特に限定されないが、好ましい範囲としては、酸化型グルタチオンの含有量が徐放性肥料の全量に対して好ましくは0.000001質量%以上、より好ましくは0.005質量%以上、好ましくは20質量%以下、より好ましくは5質量%以下である。
酸化型グルタチオンを0.000001〜20質量%、
増粘剤及び/又は結合剤(好ましくは高分子化合物、より好ましくはカルボキシメチルセルロース又はその塩)を0.01〜20質量%、
吸着性担体(特に無機多孔質材)を60〜99.98質量%
含有する徐放性肥料であり、より好ましい実施形態は、
酸化型グルタチオンを0.005〜5質量%、
増粘剤及び/又は結合剤(好ましくは高分子化合物、より好ましくはカルボキシメチルセルロース又はその塩)を0.1〜10質量%、
吸着性担体(特に無機多孔質材)を80〜99質量%
含有する徐放性肥料である。
2.4.徐放性
本発明の徐放性肥料は以下の徐放特性を有することが更に好ましい。
3.製法
本発明の徐放性肥料の製造方法は特に限定されない。
GSSGと、放出制御剤と、水又は水溶性溶媒である溶媒との混合物を形成する混合工程と、
前記混合物からGSSGと放出制御剤とを含む粒子を形成する造粒工程と
を含む方法が挙げられる。
4.対象植物
本発明の徐放性肥料を施用する対象植物は特に限定されず双子葉植物、単子葉植物等の種々の植物である。
5.施用方法
本発明の徐放性肥料を植物に施用する方法としては、本発明の徐放性肥料又は本発明の徐放性肥料から放出されたGSSGが植物の根、茎、葉などの植物体に接触することができる方法であれば特に限定されず、前記植物体に本発明の徐放性肥料が直接接するように施用してもよいし、前記植物体が定着した土壌等の栽培担体に本発明の徐放性肥料を施用してもよい。本発明の徐放性肥料は植物の根を囲む土壌等の栽培担体に対して施用した場合に、長期間にわたり安定してGSSGを植物の根に対して供給することができるため好ましい。しかし、上記の通り、本発明の徐放性肥料を植物に施用する方法は特に限定されない。
実施例1:酸化型グルタチオン徐放製剤(本発明品)の製造
1.原料組成
酸化型グルタチオン徐放製剤(本発明品という)の原料組成は以下の通りである。GSSGとしてはアンモニウム塩の形態のものを用いた。表1及び表2に示すGSSGの配合率は当該塩の形態での配合率である。
図1に示す操作フローに沿って粒子状の本発明品を調製した。
比較例1:酸化型グルタチオン非徐放製剤(比較品)の製造
1.原料組成
酸化型グルタチオン非徐放製剤(比較品という)の原料組成は以下の通りである。
図2に示す操作フローに沿って粒子状の比較品を調製した。
実施例2:酸化型グルタチオン徐放製剤からの酸化型グルタチオン溶出挙動の確認
1.試験方法
以下の手順で本発明品及び比較品の水中での酸化型グルタチオンの溶出性を評価した。
2.結果
結果を図3に示す。比較品は蒸留水との混合直後に全ての酸化型グルタチオンが溶出した。一方、本発明品では酸化型グルタチオンが徐々に水中に溶出されることが確認できた。
実施例3:酸化型グルタチオン徐放製剤の土壌中での安定性の確認
1.試験方法
本発明品及び比較品の、土壌中での安定性を以下の方法により確認した。
2.結果
各時点での酸化型グルタチオン残存率(%)を表3及び図4に示す。
実施例4:植物生長促進効果の確認
1.試験方法
以下の条件でコマツナ(タキイ種苗株式会社)の育苗を行った。比較品試験区及び本発明品試験区では、育苗試験開始時に、それぞれ1ポットあたりの酸化型グルタチオン量(フリー体としての換算量)が36mgとなるように、各3.7gの比較品又は本発明品を土壌中に添加し混和した。無処理試験区ではブランク試料として3.7gのクレーを育苗試験開始時に土壌中に添加し混和した。
期間:6週間
場所:植物栽培用インキュベーター
培土:タキイ製育苗培土、バーミキュライト
温度:20℃
光:115μmol m−2 s−1(10000lux)(明:12h/暗:12h)
試験区:無処理、比較品、本発明品
n数:3株/区
ポットサイズ(幅×奥行×高さ):7×7×5cm
6週間後に葉長及び地上部重量を測定した。
2.結果
結果を表4に示す。
実施例5:酸化型グルタチオン徐放製剤中含水量の保存安定性への影響確認
1.試験方法
以下の手順で本発明品の含水量が保存安定性に与える影響を評価した。
2.結果
結果を表5に示す。
実施例6:酸化型グルタチオン徐放製剤のpH安定性の確認
1.試験方法
以下の手順で本発明品のpH安定性を評価した。
2.結果
結果を表6に示す。
Claims (12)
- 酸化型グルタチオンと、放出制御剤とを含む、徐放性肥料。
- 放出制御剤が増粘剤、結合剤及び吸着性担体から選択される少なくとも1種である請求項1に記載の徐放性肥料。
- 放出制御剤が、カルボキシメチルセルロース又はその塩を含有する、請求項2に記載の徐放性肥料。
- 放出制御剤が、無機多孔質材を更に含有する、請求項3に記載の徐放性肥料。
- 酸化型グルタチオンを0.000001〜20質量%、
カルボキシメチルセルロース又はその塩を0.01〜20質量%、
無機多孔質材を60〜99.98質量%
含有する、請求項4に記載の徐放性肥料。 - 水中に添加し分散させたときのpHが2.0以上8.0未満である、請求項1〜5のいずれか1項に記載の徐放性肥料。
- 含水量が10質量%以下である、請求項1〜6のいずれか1項に記載の徐放性肥料。
- 酸化型グルタチオンとして、酸化型グルタチオンのアンモニウム塩、カルシウム塩又はマグネシウム塩を含有する、請求項1〜7のいずれか1項に記載の徐放性肥料。
- 酸化型グルタチオンが、放出制御剤を含む基材中に分散している、請求項1〜8のいずれか1項に記載の徐放性肥料。
- 酸化型グルタチオンと、放出制御剤と、水又は水溶性溶媒である溶媒との混合物を形成する工程と、
前記混合物から酸化型グルタチオンと放出制御剤とを含む粒子を形成する工程と
を含む方法により得られた、請求項1〜9のいずれか1項に記載の徐放性肥料。 - 30℃の温度条件において、徐放性肥料1.25gを蒸留水25mlに添加し静置するとき、当初の徐放性肥料中の酸化型グルタチオンの、酸化型グルタチオンフリー体として換算した合計質量をTとすると、水中に溶出した酸化型グルタチオンの、酸化型グルタチオンフリー体として換算した合計質量が、12時間後に0.60T以下であり、24時間後に0.80T以下であり、48時間後に0.90T以下であり、72時間後に0.95T以下である、請求項1〜10のいずれか1項に記載の徐放性肥料。
- 酸化型グルタチオンと、放出制御剤と、水又は水溶性溶媒である溶媒との混合物を形成する工程と、
前記混合物から酸化型グルタチオンと放出制御剤とを含む粒子を形成する工程と
を含む、請求項1〜11のいずれか1項に記載の徐放性肥料の製造方法。
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MA42314A (fr) * | 2015-07-03 | 2018-05-09 | Kaneka Corp | Composition d'engrais pour une application sur les feuilles et comprenant du glutathion oxydé et un constituant d'engrais |
CN108601798A (zh) | 2016-01-29 | 2018-09-28 | 小林光 | 固体制剂、固体制剂的制备方法及析氢方法 |
JP6592725B2 (ja) | 2016-08-23 | 2019-10-23 | 株式会社ボスケシリコン | 水素供給材及びその製造方法、並びに水素供給方法 |
EP3505491A4 (en) | 2016-08-23 | 2020-03-11 | Hikaru Kobayashi | COMPOUND, PRODUCTION METHOD THEREOF, AND HYDROGEN SUPPLY METHOD |
JP7023245B2 (ja) * | 2017-01-20 | 2022-02-21 | 株式会社カネカ | グルタチオンを含む粒状肥料 |
JP6902897B2 (ja) * | 2017-03-30 | 2021-07-14 | 株式会社カネカ | グルタチオン含有組成物の製造方法 |
KR101969430B1 (ko) * | 2017-10-19 | 2019-04-16 | 동아대학교 산학협력단 | 참치 부산물 및 마늘 껍질을 포함하는 서방성 고형화 아미노산 비료 및 이의 제조방법 |
JP6998253B2 (ja) * | 2018-03-28 | 2022-02-04 | 株式会社カネカ | ニンニク中のアリイン増量剤およびニンニクの栽培方法 |
WO2019189733A1 (ja) * | 2018-03-30 | 2019-10-03 | 株式会社カネカ | 酸化型グルタチオンを含む固体組成物及びその製造方法 |
CN108617653A (zh) * | 2018-05-07 | 2018-10-09 | 柯江波 | 基于滩涂淤泥的扦插繁殖用缓释抑菌剂及制备方法 |
CN108719335A (zh) * | 2018-05-07 | 2018-11-02 | 柯江波 | 用于蔬菜栽培基质处理的缓释抑菌剂及制备方法 |
US11203554B2 (en) * | 2018-12-07 | 2021-12-21 | Imerys Usa, Inc. | Anticaking agent for hygroscopic fertilizer |
JP7307026B2 (ja) | 2020-04-01 | 2023-07-11 | トヨタ自動車株式会社 | アーバスキュラー菌根菌の共生促進剤及び共生促進方法 |
CN111689811A (zh) * | 2020-06-29 | 2020-09-22 | 砀山县绿源生态肥料有限公司 | 一种缓释型促光合复混肥的制备方法 |
CN112159282A (zh) * | 2020-10-10 | 2021-01-01 | 湖北中烟工业有限责任公司 | 一种用于鄂西南烤烟的掺混控释肥及其制备方法和应用 |
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