JPWO2010137705A1 - カプセル型医療装置 - Google Patents
カプセル型医療装置 Download PDFInfo
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- JPWO2010137705A1 JPWO2010137705A1 JP2010537175A JP2010537175A JPWO2010137705A1 JP WO2010137705 A1 JPWO2010137705 A1 JP WO2010137705A1 JP 2010537175 A JP2010537175 A JP 2010537175A JP 2010537175 A JP2010537175 A JP 2010537175A JP WO2010137705 A1 JPWO2010137705 A1 JP WO2010137705A1
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- medical device
- body tissue
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
- A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/04—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
- A61B1/041—Capsule endoscopes for imaging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B34/00—Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
- A61B34/70—Manipulators specially adapted for use in surgery
- A61B34/73—Manipulators for magnetic surgery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/06—Devices, other than using radiation, for detecting or locating foreign bodies ; determining position of probes within or on the body of the patient
- A61B5/061—Determining position of a probe within the body employing means separate from the probe, e.g. sensing internal probe position employing impedance electrodes on the surface of the body
- A61B5/062—Determining position of a probe within the body employing means separate from the probe, e.g. sensing internal probe position employing impedance electrodes on the surface of the body using magnetic field
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/07—Endoradiosondes
- A61B5/073—Intestinal transmitters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14507—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14539—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring pH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/48—Other medical applications
- A61B5/4836—Diagnosis combined with treatment in closed-loop systems or methods
- A61B5/4839—Diagnosis combined with treatment in closed-loop systems or methods combined with drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
- A61B5/6861—Capsules, e.g. for swallowing or implanting
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6867—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive specially adapted to be attached or implanted in a specific body part
- A61B5/6873—Intestine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6879—Means for maintaining contact with the body
- A61B5/6882—Anchoring means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6879—Means for maintaining contact with the body
- A61B5/6884—Clamps or clips
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Surgery (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Robotics (AREA)
- Optics & Photonics (AREA)
- Pathology (AREA)
- Radiology & Medical Imaging (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Endoscopes (AREA)
Abstract
Description
1a,1b ドーム形状筐体
1c 筒状筐体
2a,2b 照明部
3a,3b 撮像部
4 無線部
5 制御部
6 電源
7 磁石
10,41,42,50,60,70,110 押圧部材
10a,41a,42a,51,61,71 基部
10b,41b,42b,51a〜51c,61a〜61e,71a,110b 枝部
11,31,31a,111 穿刺部材
12 収納部
13 バルーン
14 薬液
17 供給管
17a バルブ
18 アクチュエータ
20 体内組織
21 表層
22 臓器
100A,100B カプセル型医療装置
101,102 永久磁石
118 磁気アクチュエータ
Claims (11)
- 筐体と、
体内組織の表面を押圧する押圧部材と、
前記押圧部材を前記筐体から所定方向に突出させ、この突出させる方向と平行な回転軸を中心に前記押圧部材を回転させつつ該押圧部材に前記体内組織表面を押圧させる駆動部と、
前記押圧部材に設けられ、前記駆動部による前記押圧部材の回転駆動のもとに、前記体内組織表面に対し傾斜した方向から該体内組織を穿刺し、薬液を該体内組織に注入する針状の穿刺部材と、
を備えたことを特徴とするカプセル型医療装置。 - 前記穿刺部材は、前記押圧部材の回転軸に略垂直な平面内に設けられ、該穿刺部材の穿刺方向は、前記押圧部材の先端付近の回転軌道と接する方向であることを特徴とする請求項1に記載のカプセル型医療装置。
- 前記穿刺部材の基部は、前記押圧部材の先端から所定距離離間した基端側に位置し、かつ前記押圧部材が突出した状態下での前記穿刺部材の先端は、前記穿刺部材の基部よりも前記押圧部材の突出方向側に位置することを特徴とする請求項1に記載のカプセル型医療装置。
- 前記穿刺部材の長さおよび/または前記体内組織の表面に対する傾斜角度は、前記体内組織の表面から、薬液を注入すべき領域までの深さが大きいほど、大きな値を有することを特徴とする請求項1〜3のいずれか一つに記載のカプセル型医療装置。
- 前記押圧部材は、先端部が前記回転軸の径方向に広がるように展開することが可能であるとともに、展開前の状態に折り畳むことが可能な部材であり、前記筐体内に折り畳まれて収容され、前記筐体外に突出する場合に展開し、薬液の注入後、折り畳まれて前記筐体内に収納されることを特徴とする請求項1〜4のいずれか一つに記載のカプセル型医療装置。
- 前記押圧部材は、先端部が前記回転軸の径方向に広がるように展開することが可能な線状部材であることを特徴とする請求項1〜5のいずれか一つに記載のカプセル型医療装置。
- 前記押圧部材は、先端部が前記回転軸の径方向に広がるように展開して錐状をなす線状部材であることを特徴とする請求項6に記載のカプセル型医療装置。
- 前記駆動部は、前記穿刺部材による薬液の注入後、前記回転軸を中心に前記押圧部材を注入前とは逆方向に回転させつつ前記体内組織表面から離間させることを特徴とする請求項1〜7のいずれか一つに記載のカプセル型医療装置。
- 前記筐体内部に磁性体を設けたことを特徴とする請求項1〜8のいずれか一つに記載のカプセル型医療装置。
- 前記駆動部は、駆動用磁性体を有し、外部からの誘導磁界によって該駆動用磁性体を回転させることによって前記押圧部材を回転させつつ前記体内組織表面に押圧することを特徴とする請求項1〜9のいずれか一つに記載のカプセル型医療装置。
- 撮像手段および照明手段を備えたことを特徴とする請求項1〜10のいずれか一つに記載のカプセル型医療装置。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2009131365 | 2009-05-29 | ||
JP2009131365 | 2009-05-29 | ||
PCT/JP2010/059140 WO2010137705A1 (ja) | 2009-05-29 | 2010-05-28 | カプセル型医療装置 |
Publications (2)
Publication Number | Publication Date |
---|---|
JP4642941B2 JP4642941B2 (ja) | 2011-03-02 |
JPWO2010137705A1 true JPWO2010137705A1 (ja) | 2012-11-15 |
Family
ID=43222808
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2010537175A Expired - Fee Related JP4642941B2 (ja) | 2009-05-29 | 2010-05-28 | カプセル型医療装置 |
Country Status (3)
Country | Link |
---|---|
US (1) | US8480562B2 (ja) |
JP (1) | JP4642941B2 (ja) |
WO (1) | WO2010137705A1 (ja) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4734475B2 (ja) * | 2009-02-16 | 2011-07-27 | オリンパスメディカルシステムズ株式会社 | カプセル型医療装置 |
US9149172B2 (en) * | 2011-12-29 | 2015-10-06 | Given Imaging Ltd. | System and apparatus for anchoring and operation of in-vivo medical devices |
US9743942B2 (en) * | 2013-03-15 | 2017-08-29 | Christopher V. Beckman | Nanotechnology and other small scale injectable machines with multistage external magnetic and electrostatic actuation |
WO2016155671A1 (zh) * | 2015-04-02 | 2016-10-06 | 傅君志 | 可吞咽式装置 |
JP7219723B2 (ja) | 2017-05-17 | 2023-02-08 | マサチューセッツ インスティテュート オブ テクノロジー | 自己復元システムならびに関連構成要素および方法 |
US11541015B2 (en) | 2017-05-17 | 2023-01-03 | Massachusetts Institute Of Technology | Self-righting systems, methods, and related components |
US11690550B2 (en) * | 2017-07-26 | 2023-07-04 | The General Hospital Corporation | System and method for an ingestible physiological monitor |
CN108095806B (zh) * | 2017-12-16 | 2023-04-28 | 重庆金山科技(集团)有限公司 | 带自锁功能的吸附穿刺固定装置 |
AU2019269636A1 (en) | 2018-05-17 | 2020-11-19 | Massachusetts Institute Of Technology | Systems for electrical stimulation |
AU2019269638A1 (en) * | 2018-05-17 | 2020-11-19 | Massachusetts Institute Of Technology | Quick release capsules |
EP3880177A4 (en) * | 2018-11-15 | 2022-10-12 | Massachusetts Institute of Technology | ACTUATION COMPONENTS AND RELATED PROCEDURES |
US11771829B2 (en) | 2019-02-01 | 2023-10-03 | Massachusetts Institute Of Technology | Systems and methods for liquid injection |
CN114650864A (zh) * | 2019-10-01 | 2022-06-21 | 拉尼医疗有限公司 | 用于将制剂递送到管腔壁的自定尺寸装置 |
US11541216B2 (en) | 2019-11-21 | 2023-01-03 | Massachusetts Institute Of Technology | Methods for manufacturing tissue interfacing components |
CN113598690B (zh) * | 2021-08-10 | 2023-07-28 | 安徽光阵光电科技有限公司 | 一种用于人体体内医疗的内窥镜药丸 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5819233A (ja) * | 1981-07-29 | 1983-02-04 | オリンパス光学工業株式会社 | 医療用カプセル |
JPH04144533A (ja) * | 1990-10-05 | 1992-05-19 | Olympus Optical Co Ltd | 内視鏡 |
US6102887A (en) * | 1998-08-11 | 2000-08-15 | Biocardia, Inc. | Catheter drug delivery system and method for use |
US7914442B1 (en) * | 1999-03-01 | 2011-03-29 | Gazdzinski Robert F | Endoscopic smart probe and method |
US6283947B1 (en) * | 1999-07-13 | 2001-09-04 | Advanced Cardiovascular Systems, Inc. | Local drug delivery injection catheter |
JP2002000556A (ja) * | 2000-06-26 | 2002-01-08 | Nonomura Tomosuke | 内視鏡 |
JP4231657B2 (ja) * | 2002-05-10 | 2009-03-04 | オリンパス株式会社 | カプセル型医療装置 |
JP2006512130A (ja) * | 2002-12-26 | 2006-04-13 | ギブン・イメージング・リミテツド | 不動化可能な生体内センシング装置 |
US7066879B2 (en) * | 2003-07-15 | 2006-06-27 | The Trustees Of Columbia University In The City Of New York | Insertable device and system for minimal access procedure |
WO2005112460A2 (en) * | 2004-05-17 | 2005-11-24 | Given Imaging Ltd. | Method, system and device for in-vivo biopsy |
JP4358821B2 (ja) * | 2005-12-15 | 2009-11-04 | オリンパス株式会社 | 被検体内導入装置 |
US20090137866A1 (en) * | 2007-11-28 | 2009-05-28 | Searete Llc, A Limited Liability Corporation Of The State Delaware | Medical or veterinary digestive tract utilization systems and methods |
-
2010
- 2010-05-28 WO PCT/JP2010/059140 patent/WO2010137705A1/ja active Application Filing
- 2010-05-28 JP JP2010537175A patent/JP4642941B2/ja not_active Expired - Fee Related
- 2010-10-05 US US12/897,955 patent/US8480562B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
US8480562B2 (en) | 2013-07-09 |
US20110207998A1 (en) | 2011-08-25 |
JP4642941B2 (ja) | 2011-03-02 |
WO2010137705A1 (ja) | 2010-12-02 |
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