JPS649573B2 - - Google Patents
Info
- Publication number
- JPS649573B2 JPS649573B2 JP55183836A JP18383680A JPS649573B2 JP S649573 B2 JPS649573 B2 JP S649573B2 JP 55183836 A JP55183836 A JP 55183836A JP 18383680 A JP18383680 A JP 18383680A JP S649573 B2 JPS649573 B2 JP S649573B2
- Authority
- JP
- Japan
- Prior art keywords
- reaction
- values
- measurement
- sample
- time
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000006243 chemical reaction Methods 0.000 claims description 24
- 238000000691 measurement method Methods 0.000 claims description 4
- 230000005856 abnormality Effects 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 238000005259 measurement Methods 0.000 description 20
- 239000000523 sample Substances 0.000 description 14
- 230000005284 excitation Effects 0.000 description 9
- 238000000034 method Methods 0.000 description 7
- 230000008569 process Effects 0.000 description 5
- 230000004044 response Effects 0.000 description 5
- 238000010586 diagram Methods 0.000 description 4
- 230000028161 membrane depolarization Effects 0.000 description 4
- 239000012472 biological sample Substances 0.000 description 3
- 210000004027 cell Anatomy 0.000 description 3
- 239000000725 suspension Substances 0.000 description 3
- 230000001360 synchronised effect Effects 0.000 description 3
- 230000002776 aggregation Effects 0.000 description 2
- 239000003153 chemical reaction reagent Substances 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000001914 filtration Methods 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 210000004698 lymphocyte Anatomy 0.000 description 2
- 238000005054 agglomeration Methods 0.000 description 1
- 238000004220 aggregation Methods 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 238000004062 sedimentation Methods 0.000 description 1
- 238000002798 spectrophotometry method Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/27—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration
- G01N21/272—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration for following a reaction, e.g. for determining photometrically a reaction rate (photometric cinetic analysis)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/21—Polarisation-affecting properties
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6445—Measuring fluorescence polarisation
Landscapes
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Pathology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Mathematical Physics (AREA)
- Theoretical Computer Science (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55183836A JPS57108643A (en) | 1980-12-26 | 1980-12-26 | Method for measuring reaction |
US06/333,413 US4429230A (en) | 1980-12-26 | 1981-12-22 | Fluorescence polarization analyzer |
EP81306039A EP0055914B1 (en) | 1980-12-26 | 1981-12-22 | Fluorescence polarization analyzer |
DE8181306039T DE3176092D1 (en) | 1980-12-26 | 1981-12-22 | Fluorescence polarization analyzer |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55183836A JPS57108643A (en) | 1980-12-26 | 1980-12-26 | Method for measuring reaction |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS57108643A JPS57108643A (en) | 1982-07-06 |
JPS649573B2 true JPS649573B2 (US08197722-20120612-C00042.png) | 1989-02-17 |
Family
ID=16142683
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP55183836A Granted JPS57108643A (en) | 1980-12-26 | 1980-12-26 | Method for measuring reaction |
Country Status (4)
Country | Link |
---|---|
US (1) | US4429230A (US08197722-20120612-C00042.png) |
EP (1) | EP0055914B1 (US08197722-20120612-C00042.png) |
JP (1) | JPS57108643A (US08197722-20120612-C00042.png) |
DE (1) | DE3176092D1 (US08197722-20120612-C00042.png) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6125030A (ja) * | 1984-07-13 | 1986-02-03 | Hitachi Ltd | 螢光偏光測定装置 |
JPH0650315B2 (ja) * | 1985-11-08 | 1994-06-29 | 株式会社日立製作所 | 免疫分析用試薬および免疫分析方法 |
US5166052A (en) * | 1986-05-27 | 1992-11-24 | Boris Cercek | Method for measuring polarization of bathochromically shifted fluorescence |
US5894532A (en) * | 1997-04-04 | 1999-04-13 | Massachusetts Institute Of Technology | Polarization desensitizer |
EP1489419A1 (en) * | 2002-03-27 | 2004-12-22 | Matsushita Electric Industrial Co., Ltd. | Fluorescent polarization method, kit used therefor and biosensor |
ITMI20061502A1 (it) * | 2006-07-28 | 2008-01-29 | Barilla Flli G & R Spa | Procedimento ed apparecchiatura per la determinazione rapida di deossinivalenolo in una matrice a base di cereali. |
US9006283B2 (en) * | 2007-07-12 | 2015-04-14 | Acumen Pharmaceuticals, Inc. | Methods of modifying amyloid β oligomers using non-peptidic compounds |
US20110098309A1 (en) * | 2007-07-12 | 2011-04-28 | Acumen Pharmaceuticals, Inc. | Methods of inhibiting the formation of amyloid-beta diffusable ligands using acylhydrazide compounds |
US8962677B2 (en) * | 2007-07-12 | 2015-02-24 | Acumen Pharmaceuticals, Inc. | Methods of restoring cognitive ability using non-peptidic compounds |
WO2009079566A2 (en) | 2007-12-18 | 2009-06-25 | Acumen Pharmaceuticals, Inc. | Novel addl receptor polypeptides, polynucleotides and host cells for recombinant production |
JP5599219B2 (ja) * | 2010-04-20 | 2014-10-01 | 株式会社日立ハイテクノロジーズ | 自動分析装置及び自動分析方法 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL49776A (en) * | 1976-06-13 | 1979-05-31 | Elscint Ltd | Method and appararus for differentiating of normal and abnormal mammalian cells |
JPS55109949A (en) * | 1979-02-16 | 1980-08-23 | Hitachi Ltd | Spectro-fluorophotometer |
-
1980
- 1980-12-26 JP JP55183836A patent/JPS57108643A/ja active Granted
-
1981
- 1981-12-22 US US06/333,413 patent/US4429230A/en not_active Expired - Fee Related
- 1981-12-22 EP EP81306039A patent/EP0055914B1/en not_active Expired
- 1981-12-22 DE DE8181306039T patent/DE3176092D1/de not_active Expired
Also Published As
Publication number | Publication date |
---|---|
EP0055914A3 (en) | 1983-11-23 |
DE3176092D1 (en) | 1987-05-14 |
US4429230A (en) | 1984-01-31 |
JPS57108643A (en) | 1982-07-06 |
EP0055914B1 (en) | 1987-04-08 |
EP0055914A2 (en) | 1982-07-14 |
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