JPS6354320A - 抗アルコ−ル症組成物 - Google Patents
抗アルコ−ル症組成物Info
- Publication number
- JPS6354320A JPS6354320A JP61199448A JP19944886A JPS6354320A JP S6354320 A JPS6354320 A JP S6354320A JP 61199448 A JP61199448 A JP 61199448A JP 19944886 A JP19944886 A JP 19944886A JP S6354320 A JPS6354320 A JP S6354320A
- Authority
- JP
- Japan
- Prior art keywords
- glutamine
- alanine
- alcohol
- group
- administration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 19
- 230000002075 anti-alcohol Effects 0.000 title abstract description 3
- 201000010099 disease Diseases 0.000 title abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 2
- QNAYBMKLOCPYGJ-REOHCLBHSA-N L-alanine Chemical compound C[C@H](N)C(O)=O QNAYBMKLOCPYGJ-REOHCLBHSA-N 0.000 claims abstract description 28
- 235000004279 alanine Nutrition 0.000 claims abstract description 27
- ZDXPYRJPNDTMRX-UHFFFAOYSA-N glutamine Natural products OC(=O)C(N)CCC(N)=O ZDXPYRJPNDTMRX-UHFFFAOYSA-N 0.000 claims abstract description 25
- 150000003839 salts Chemical class 0.000 claims abstract description 9
- 208000007848 Alcoholism Diseases 0.000 claims description 4
- 201000007930 alcohol dependence Diseases 0.000 claims description 4
- ZDXPYRJPNDTMRX-VKHMYHEASA-N L-glutamine Chemical compound OC(=O)[C@@H](N)CCC(N)=O ZDXPYRJPNDTMRX-VKHMYHEASA-N 0.000 abstract description 16
- 235000013305 food Nutrition 0.000 abstract description 13
- 239000003814 drug Substances 0.000 abstract description 4
- 235000011194 food seasoning agent Nutrition 0.000 abstract description 2
- 235000018102 proteins Nutrition 0.000 abstract description 2
- 108090000623 proteins and genes Proteins 0.000 abstract description 2
- 102000004169 proteins and genes Human genes 0.000 abstract description 2
- 239000000126 substance Substances 0.000 abstract description 2
- 239000000463 material Substances 0.000 abstract 3
- 229940079593 drug Drugs 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 41
- 235000001014 amino acid Nutrition 0.000 description 16
- 229940024606 amino acid Drugs 0.000 description 16
- 150000001413 amino acids Chemical class 0.000 description 16
- 241001465754 Metazoa Species 0.000 description 11
- 230000000694 effects Effects 0.000 description 11
- 239000000243 solution Substances 0.000 description 11
- 239000008280 blood Substances 0.000 description 8
- 210000004369 blood Anatomy 0.000 description 8
- 235000002639 sodium chloride Nutrition 0.000 description 6
- 235000000346 sugar Nutrition 0.000 description 5
- 201000004384 Alopecia Diseases 0.000 description 4
- 230000003247 decreasing effect Effects 0.000 description 4
- 208000024963 hair loss Diseases 0.000 description 4
- 230000003676 hair loss Effects 0.000 description 4
- 238000002360 preparation method Methods 0.000 description 4
- 125000003412 L-alanyl group Chemical group [H]N([H])[C@@](C([H])([H])[H])(C(=O)[*])[H] 0.000 description 3
- 241000699670 Mus sp. Species 0.000 description 3
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 3
- 229920002472 Starch Polymers 0.000 description 3
- 235000013527 bean curd Nutrition 0.000 description 3
- 230000003542 behavioural effect Effects 0.000 description 3
- 238000001802 infusion Methods 0.000 description 3
- 239000003921 oil Substances 0.000 description 3
- 235000019198 oils Nutrition 0.000 description 3
- 235000015067 sauces Nutrition 0.000 description 3
- 230000004580 weight loss Effects 0.000 description 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- AHLPHDHHMVZTML-BYPYZUCNSA-N L-Ornithine Chemical compound NCCC[C@H](N)C(O)=O AHLPHDHHMVZTML-BYPYZUCNSA-N 0.000 description 2
- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 description 2
- AYFVYJQAPQTCCC-GBXIJSLDSA-N L-threonine Chemical compound C[C@@H](O)[C@H](N)C(O)=O AYFVYJQAPQTCCC-GBXIJSLDSA-N 0.000 description 2
- KZSNJWFQEVHDMF-BYPYZUCNSA-N L-valine Chemical compound CC(C)[C@H](N)C(O)=O KZSNJWFQEVHDMF-BYPYZUCNSA-N 0.000 description 2
- 206010067125 Liver injury Diseases 0.000 description 2
- AHLPHDHHMVZTML-UHFFFAOYSA-N Orn-delta-NH2 Natural products NCCCC(N)C(O)=O AHLPHDHHMVZTML-UHFFFAOYSA-N 0.000 description 2
- UTJLXEIPEHZYQJ-UHFFFAOYSA-N Ornithine Natural products OC(=O)C(C)CCCN UTJLXEIPEHZYQJ-UHFFFAOYSA-N 0.000 description 2
- 241000700159 Rattus Species 0.000 description 2
- 235000013334 alcoholic beverage Nutrition 0.000 description 2
- 230000037396 body weight Effects 0.000 description 2
- 208000019425 cirrhosis of liver Diseases 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 235000005911 diet Nutrition 0.000 description 2
- 230000037213 diet Effects 0.000 description 2
- 239000003925 fat Substances 0.000 description 2
- 231100000234 hepatic damage Toxicity 0.000 description 2
- 230000005764 inhibitory process Effects 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 210000004185 liver Anatomy 0.000 description 2
- 230000008818 liver damage Effects 0.000 description 2
- 229960003104 ornithine Drugs 0.000 description 2
- 230000036470 plasma concentration Effects 0.000 description 2
- 235000019992 sake Nutrition 0.000 description 2
- 230000001953 sensory effect Effects 0.000 description 2
- 239000011780 sodium chloride Substances 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 235000019698 starch Nutrition 0.000 description 2
- 239000008107 starch Substances 0.000 description 2
- 210000001321 subclavian vein Anatomy 0.000 description 2
- 239000000725 suspension Substances 0.000 description 2
- 208000022309 Alcoholic Liver disease Diseases 0.000 description 1
- 241000972773 Aulopiformes Species 0.000 description 1
- 241000282472 Canis lupus familiaris Species 0.000 description 1
- 235000002568 Capsicum frutescens Nutrition 0.000 description 1
- 101000957724 Catostomus commersonii Corticoliberin-1 Proteins 0.000 description 1
- 241000238366 Cephalopoda Species 0.000 description 1
- 241000555825 Clupeidae Species 0.000 description 1
- 235000016795 Cola Nutrition 0.000 description 1
- 244000228088 Cola acuminata Species 0.000 description 1
- 235000011824 Cola pachycarpa Nutrition 0.000 description 1
- AEMOLEFTQBMNLQ-AQKNRBDQSA-N D-glucopyranuronic acid Chemical compound OC1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O AEMOLEFTQBMNLQ-AQKNRBDQSA-N 0.000 description 1
- 239000004278 EU approved seasoning Substances 0.000 description 1
- 208000004930 Fatty Liver Diseases 0.000 description 1
- IAJILQKETJEXLJ-UHFFFAOYSA-N Galacturonsaeure Natural products O=CC(O)C(O)C(O)C(O)C(O)=O IAJILQKETJEXLJ-UHFFFAOYSA-N 0.000 description 1
- 108010010803 Gelatin Proteins 0.000 description 1
- 206010019708 Hepatic steatosis Diseases 0.000 description 1
- 208000013016 Hypoglycemia Diseases 0.000 description 1
- ODKSFYDXXFIFQN-BYPYZUCNSA-N L-arginine Chemical compound OC(=O)[C@@H](N)CCCN=C(N)N ODKSFYDXXFIFQN-BYPYZUCNSA-N 0.000 description 1
- CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 description 1
- ROHFNLRQFUQHCH-YFKPBYRVSA-N L-leucine Chemical compound CC(C)C[C@H](N)C(O)=O ROHFNLRQFUQHCH-YFKPBYRVSA-N 0.000 description 1
- KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 description 1
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 description 1
- COLNVLDHVKWLRT-QMMMGPOBSA-N L-phenylalanine Chemical compound OC(=O)[C@@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-QMMMGPOBSA-N 0.000 description 1
- QIVBCDIJIAJPQS-VIFPVBQESA-N L-tryptophane Chemical compound C1=CC=C2C(C[C@H](N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-VIFPVBQESA-N 0.000 description 1
- 244000137850 Marrubium vulgare Species 0.000 description 1
- -1 Merck Substances 0.000 description 1
- 241001502129 Mullus Species 0.000 description 1
- 241000237502 Ostreidae Species 0.000 description 1
- 235000010627 Phaseolus vulgaris Nutrition 0.000 description 1
- 244000046052 Phaseolus vulgaris Species 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 238000010171 animal model Methods 0.000 description 1
- 229960003589 arginine hydrochloride Drugs 0.000 description 1
- 125000003118 aryl group Chemical group 0.000 description 1
- 235000013405 beer Nutrition 0.000 description 1
- 150000005693 branched-chain amino acids Chemical class 0.000 description 1
- 238000009395 breeding Methods 0.000 description 1
- 230000001488 breeding effect Effects 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 235000013351 cheese Nutrition 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- ZPUCINDJVBIVPJ-LJISPDSOSA-N cocaine Chemical compound O([C@H]1C[C@@H]2CC[C@@H](N2C)[C@H]1C(=O)OC)C(=O)C1=CC=CC=C1 ZPUCINDJVBIVPJ-LJISPDSOSA-N 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 235000014113 dietary fatty acids Nutrition 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 239000008298 dragée Substances 0.000 description 1
- 235000015071 dressings Nutrition 0.000 description 1
- 239000000839 emulsion Substances 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 229930195729 fatty acid Natural products 0.000 description 1
- 239000000194 fatty acid Substances 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- 208000010706 fatty liver disease Diseases 0.000 description 1
- 230000037406 food intake Effects 0.000 description 1
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 1
- 229920000159 gelatin Polymers 0.000 description 1
- 239000008273 gelatin Substances 0.000 description 1
- 235000019322 gelatine Nutrition 0.000 description 1
- 235000011852 gelatine desserts Nutrition 0.000 description 1
- 230000003087 glucogenic effect Effects 0.000 description 1
- 229940097043 glucuronic acid Drugs 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 230000002440 hepatic effect Effects 0.000 description 1
- 230000002218 hypoglycaemic effect Effects 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 230000035987 intoxication Effects 0.000 description 1
- 231100000566 intoxication Toxicity 0.000 description 1
- 230000000873 masking effect Effects 0.000 description 1
- 239000008268 mayonnaise Substances 0.000 description 1
- 235000010746 mayonnaise Nutrition 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 235000020636 oyster Nutrition 0.000 description 1
- 210000004738 parenchymal cell Anatomy 0.000 description 1
- 238000007911 parenteral administration Methods 0.000 description 1
- 239000008194 pharmaceutical composition Substances 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- 235000013606 potato chips Nutrition 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 235000019685 rice crackers Nutrition 0.000 description 1
- 235000019515 salmon Nutrition 0.000 description 1
- 235000019512 sardine Nutrition 0.000 description 1
- 235000020083 shōchū Nutrition 0.000 description 1
- 235000014214 soft drink Nutrition 0.000 description 1
- 235000013555 soy sauce Nutrition 0.000 description 1
- 235000011496 sports drink Nutrition 0.000 description 1
- 231100000240 steatosis hepatitis Toxicity 0.000 description 1
- 239000007940 sugar coated tablet Substances 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 235000015193 tomato juice Nutrition 0.000 description 1
- 235000021419 vinegar Nutrition 0.000 description 1
- 239000000052 vinegar Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 235000015041 whisky Nutrition 0.000 description 1
- 235000014101 wine Nutrition 0.000 description 1
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP61199448A JPS6354320A (ja) | 1986-08-26 | 1986-08-26 | 抗アルコ−ル症組成物 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP61199448A JPS6354320A (ja) | 1986-08-26 | 1986-08-26 | 抗アルコ−ル症組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS6354320A true JPS6354320A (ja) | 1988-03-08 |
| JPH0420409B2 JPH0420409B2 (enExample) | 1992-04-02 |
Family
ID=16407982
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP61199448A Granted JPS6354320A (ja) | 1986-08-26 | 1986-08-26 | 抗アルコ−ル症組成物 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6354320A (enExample) |
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6339104B1 (en) | 1998-04-16 | 2002-01-15 | The City Of Osaka | Therapeutic agent for primary biliary cirrhosis |
| JP2002226369A (ja) * | 2001-01-30 | 2002-08-14 | Otsuka Pharmaceut Co Ltd | グルタミン含有経口組成物 |
| WO2002074302A1 (en) * | 2001-03-15 | 2002-09-26 | Riken | Amino acid compositions for ameliorating liver failure |
| WO2002098405A1 (fr) * | 2001-06-05 | 2002-12-12 | Ajinomoto Co., Inc. | Inhibiteurs de fibrose du foie |
| WO2003088987A1 (en) * | 2002-04-19 | 2003-10-30 | Sanwa Shurui Co., Ltd. | Composition obtained from barley shochu stillage and having effects of inhibiting the onset of alcoholic liver injury and healing it as well as favorable taste, and process for producing the same |
| WO2005058306A1 (ja) * | 2003-12-16 | 2005-06-30 | Riken | グルタミン含有エネルギー付加型アミノ酸組成物又はアミノ酸溶液 |
| JP5801515B1 (ja) * | 2014-05-08 | 2015-10-28 | アサヒグループホールディングス株式会社 | トマト含有飲食品 |
| JP2016086715A (ja) * | 2014-10-31 | 2016-05-23 | アサヒグループホールディングス株式会社 | ニンジン由来成分含有飲食品 |
| WO2016103544A1 (ja) * | 2014-12-22 | 2016-06-30 | アサヒグループホールディングス株式会社 | 食物繊維含有飲食品 |
| JP2016119880A (ja) * | 2014-12-25 | 2016-07-07 | アサヒグループホールディングス株式会社 | 野菜由来成分含有飲食品 |
| CN107177430A (zh) * | 2017-07-05 | 2017-09-19 | 无锡丝润生物技术有限公司 | 一种富含蚕蛹氨基酸的啤酒及生产工艺 |
-
1986
- 1986-08-26 JP JP61199448A patent/JPS6354320A/ja active Granted
Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6339104B1 (en) | 1998-04-16 | 2002-01-15 | The City Of Osaka | Therapeutic agent for primary biliary cirrhosis |
| JP2002226369A (ja) * | 2001-01-30 | 2002-08-14 | Otsuka Pharmaceut Co Ltd | グルタミン含有経口組成物 |
| WO2002074302A1 (en) * | 2001-03-15 | 2002-09-26 | Riken | Amino acid compositions for ameliorating liver failure |
| WO2002098405A1 (fr) * | 2001-06-05 | 2002-12-12 | Ajinomoto Co., Inc. | Inhibiteurs de fibrose du foie |
| WO2003088987A1 (en) * | 2002-04-19 | 2003-10-30 | Sanwa Shurui Co., Ltd. | Composition obtained from barley shochu stillage and having effects of inhibiting the onset of alcoholic liver injury and healing it as well as favorable taste, and process for producing the same |
| WO2005058306A1 (ja) * | 2003-12-16 | 2005-06-30 | Riken | グルタミン含有エネルギー付加型アミノ酸組成物又はアミノ酸溶液 |
| JP5801515B1 (ja) * | 2014-05-08 | 2015-10-28 | アサヒグループホールディングス株式会社 | トマト含有飲食品 |
| WO2015170605A1 (ja) * | 2014-05-08 | 2015-11-12 | アサヒグループホールディングス株式会社 | トマト含有飲食品 |
| JP2016086715A (ja) * | 2014-10-31 | 2016-05-23 | アサヒグループホールディングス株式会社 | ニンジン由来成分含有飲食品 |
| WO2016103544A1 (ja) * | 2014-12-22 | 2016-06-30 | アサヒグループホールディングス株式会社 | 食物繊維含有飲食品 |
| JPWO2016103544A1 (ja) * | 2014-12-22 | 2017-09-28 | アサヒグループホールディングス株式会社 | 食物繊維含有飲食品 |
| JP2016119880A (ja) * | 2014-12-25 | 2016-07-07 | アサヒグループホールディングス株式会社 | 野菜由来成分含有飲食品 |
| CN107177430A (zh) * | 2017-07-05 | 2017-09-19 | 无锡丝润生物技术有限公司 | 一种富含蚕蛹氨基酸的啤酒及生产工艺 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0420409B2 (enExample) | 1992-04-02 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CA2702045C (en) | Rapid-acting, blood-arginine-level-increasable oral preparation comprising citrulline and arginine | |
| CA2280612C (en) | Amino acid-sugar composition | |
| JP2014009216A (ja) | ペプチドおよび／または遊離アミノ酸を含有する組成物 | |
| JP6193229B2 (ja) | 血管内皮機能低下の予防または改善剤 | |
| JP2009173634A (ja) | ポリ−γ−グルタミン酸を含有する脂質吸収阻害剤 | |
| JPS6354320A (ja) | 抗アルコ−ル症組成物 | |
| JPWO2004019928A1 (ja) | 肝疾患治療剤 | |
| US4596825A (en) | Method of treating liver disturbances resulting from alcohol consumption and a composition therefor | |
| JP2002065212A (ja) | 筋強化用食品組成物及び筋強化剤 | |
| WO2001091762A1 (en) | Zinc-supplementary compositions for oral administration | |
| JPH0667831B2 (ja) | 肝物質合成機能障害改善用のアミノ酸組成物 | |
| US6506552B2 (en) | Amino acid-trehalose composition | |
| JP2002338473A (ja) | 抗疲労組成物 | |
| JP2006304792A (ja) | 内臓脂肪蓄積抑制食品 | |
| JPH0416166A (ja) | 経口摂取組成物 | |
| JP2008088162A (ja) | 睡眠補助剤および睡眠補助食品 | |
| JP4873778B2 (ja) | 抗疲労剤 | |
| WO2006006729A1 (ja) | Ｃ型肝炎ウイルス陽性ヒト肝硬変患者用肝癌発生・進展抑制剤 | |
| JP4300753B2 (ja) | 貧血抑制剤及び食欲抑制剤 | |
| JPH03275630A (ja) | 肝機能改善剤及び肝機能改善食品又は飲料 | |
| JP2004231585A (ja) | 生体内ホモシステインレベル低減用および上昇抑制用組成物 | |
| JP2010006764A (ja) | タンパク同化促進剤 | |
| JPH075459B2 (ja) | 抗アルコール性肝障害組成物 | |
| JP2007137816A (ja) | コレステロール再上昇抑制用組成物およびその用法 | |
| WO2007086565A1 (ja) | 成長ホルモンの分泌調節剤 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EXPY | Cancellation because of completion of term |