JPS63225509A - 炭酸アパタイト粉体の製造方法 - Google Patents
炭酸アパタイト粉体の製造方法Info
- Publication number
- JPS63225509A JPS63225509A JP5798787A JP5798787A JPS63225509A JP S63225509 A JPS63225509 A JP S63225509A JP 5798787 A JP5798787 A JP 5798787A JP 5798787 A JP5798787 A JP 5798787A JP S63225509 A JPS63225509 A JP S63225509A
- Authority
- JP
- Japan
- Prior art keywords
- reaction
- apatite powder
- producing carbonated
- carbonated apatite
- powder
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229910052586 apatite Inorganic materials 0.000 title claims description 15
- VSIIXMUUUJUKCM-UHFFFAOYSA-D pentacalcium;fluoride;triphosphate Chemical compound [F-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O VSIIXMUUUJUKCM-UHFFFAOYSA-D 0.000 title claims description 15
- 239000000843 powder Substances 0.000 title claims description 8
- 238000004519 manufacturing process Methods 0.000 title claims description 4
- 238000000034 method Methods 0.000 claims description 11
- 230000007062 hydrolysis Effects 0.000 claims description 3
- 238000006460 hydrolysis reaction Methods 0.000 claims description 3
- 229910052731 fluorine Inorganic materials 0.000 claims description 2
- 239000011737 fluorine Substances 0.000 claims description 2
- -1 fluorine ions Chemical class 0.000 claims description 2
- 238000006243 chemical reaction Methods 0.000 description 13
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 description 8
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 6
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 4
- 239000011575 calcium Substances 0.000 description 4
- 238000002156 mixing Methods 0.000 description 4
- 229910021529 ammonia Inorganic materials 0.000 description 3
- 238000007796 conventional method Methods 0.000 description 3
- 239000002994 raw material Substances 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 229910000019 calcium carbonate Inorganic materials 0.000 description 2
- 235000010216 calcium carbonate Nutrition 0.000 description 2
- 230000000052 comparative effect Effects 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 229910000392 octacalcium phosphate Inorganic materials 0.000 description 2
- 238000011017 operating method Methods 0.000 description 2
- 239000003960 organic solvent Substances 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- YIGWVOWKHUSYER-UHFFFAOYSA-F tetracalcium;hydrogen phosphate;diphosphate Chemical compound [Ca+2].[Ca+2].[Ca+2].[Ca+2].OP([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O YIGWVOWKHUSYER-UHFFFAOYSA-F 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 239000003463 adsorbent Substances 0.000 description 1
- LDDQLRUQCUTJBB-UHFFFAOYSA-N ammonium fluoride Chemical compound [NH4+].[F-] LDDQLRUQCUTJBB-UHFFFAOYSA-N 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 239000012620 biological material Substances 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- FUFJGUQYACFECW-UHFFFAOYSA-L calcium hydrogenphosphate Chemical compound [Ca+2].OP([O-])([O-])=O FUFJGUQYACFECW-UHFFFAOYSA-L 0.000 description 1
- 159000000007 calcium salts Chemical class 0.000 description 1
- 150000004649 carbonic acid derivatives Chemical class 0.000 description 1
- 239000013256 coordination polymer Substances 0.000 description 1
- 235000019700 dicalcium phosphate Nutrition 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 238000000227 grinding Methods 0.000 description 1
- 230000003301 hydrolyzing effect Effects 0.000 description 1
- 229910052588 hydroxylapatite Inorganic materials 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 229910010272 inorganic material Inorganic materials 0.000 description 1
- 239000013067 intermediate product Substances 0.000 description 1
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 description 1
- 235000021317 phosphate Nutrition 0.000 description 1
- 150000003013 phosphoric acid derivatives Chemical class 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 230000001376 precipitating effect Effects 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 239000012429 reaction media Substances 0.000 description 1
- 230000035484 reaction time Effects 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Landscapes
- Materials For Medical Uses (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP5798787A JPS63225509A (ja) | 1987-03-13 | 1987-03-13 | 炭酸アパタイト粉体の製造方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP5798787A JPS63225509A (ja) | 1987-03-13 | 1987-03-13 | 炭酸アパタイト粉体の製造方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS63225509A true JPS63225509A (ja) | 1988-09-20 |
| JPH0517167B2 JPH0517167B2 (enrdf_load_stackoverflow) | 1993-03-08 |
Family
ID=13071360
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP5798787A Granted JPS63225509A (ja) | 1987-03-13 | 1987-03-13 | 炭酸アパタイト粉体の製造方法 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS63225509A (enrdf_load_stackoverflow) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0625490A1 (en) * | 1993-05-19 | 1994-11-23 | Queen Mary And Westfield College | Method for the preparation of carbonated hydroxyapatite compositions |
| JP2008501643A (ja) * | 2004-05-06 | 2008-01-24 | イノフォス インコーポレーテッド | 新規ヒドロキシアパタイトリン酸カルシウム、その調製法およびその用途 |
| JP2012148903A (ja) * | 2011-01-17 | 2012-08-09 | Mikimoto Pharmaceut Co Ltd | ヒドロキシアパタイトの製造方法 |
| JP2020521597A (ja) * | 2017-06-02 | 2020-07-27 | ザ ユニバーシティ オブ ウェスタン オーストラリア | 石灰化組織代替物の製造方法 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61151011A (ja) * | 1984-12-25 | 1986-07-09 | Central Glass Co Ltd | 炭酸含有ヒドロキシアパタイトの製造法 |
-
1987
- 1987-03-13 JP JP5798787A patent/JPS63225509A/ja active Granted
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61151011A (ja) * | 1984-12-25 | 1986-07-09 | Central Glass Co Ltd | 炭酸含有ヒドロキシアパタイトの製造法 |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0625490A1 (en) * | 1993-05-19 | 1994-11-23 | Queen Mary And Westfield College | Method for the preparation of carbonated hydroxyapatite compositions |
| JP2008501643A (ja) * | 2004-05-06 | 2008-01-24 | イノフォス インコーポレーテッド | 新規ヒドロキシアパタイトリン酸カルシウム、その調製法およびその用途 |
| EP1753438A4 (en) * | 2004-05-06 | 2011-12-28 | Innophos Inc | New hydroxapatite calcium phosphates, their method of preparation and their applications |
| JP2012148903A (ja) * | 2011-01-17 | 2012-08-09 | Mikimoto Pharmaceut Co Ltd | ヒドロキシアパタイトの製造方法 |
| JP2020521597A (ja) * | 2017-06-02 | 2020-07-27 | ザ ユニバーシティ オブ ウェスタン オーストラリア | 石灰化組織代替物の製造方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0517167B2 (enrdf_load_stackoverflow) | 1993-03-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EXPY | Cancellation because of completion of term |