JPS6281327A - 人トロンビン製剤の加熱処理方法 - Google Patents
人トロンビン製剤の加熱処理方法Info
- Publication number
- JPS6281327A JPS6281327A JP60222453A JP22245385A JPS6281327A JP S6281327 A JPS6281327 A JP S6281327A JP 60222453 A JP60222453 A JP 60222453A JP 22245385 A JP22245385 A JP 22245385A JP S6281327 A JPS6281327 A JP S6281327A
- Authority
- JP
- Japan
- Prior art keywords
- thrombin
- heat treatment
- stabilizer
- heating
- virus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP60222453A JPS6281327A (ja) | 1985-10-04 | 1985-10-04 | 人トロンビン製剤の加熱処理方法 |
KR1019860008265A KR950010321B1 (ko) | 1985-10-04 | 1986-10-02 | 인간 트롬빈 제제의 가열처리방법 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP60222453A JPS6281327A (ja) | 1985-10-04 | 1985-10-04 | 人トロンビン製剤の加熱処理方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS6281327A true JPS6281327A (ja) | 1987-04-14 |
JPH0376292B2 JPH0376292B2 (enrdf_load_stackoverflow) | 1991-12-05 |
Family
ID=16782647
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP60222453A Granted JPS6281327A (ja) | 1985-10-04 | 1985-10-04 | 人トロンビン製剤の加熱処理方法 |
Country Status (2)
Country | Link |
---|---|
JP (1) | JPS6281327A (enrdf_load_stackoverflow) |
KR (1) | KR950010321B1 (enrdf_load_stackoverflow) |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS649937A (en) * | 1987-05-22 | 1989-01-13 | Armour Pharma | Stabilization of biological and pharmacological product of virus and bacteria infected matter in thermal inactivation |
JPH01121224A (ja) * | 1987-11-04 | 1989-05-12 | Green Cross Corp:The | トロンビン含有医薬組成物 |
JPH0253732A (ja) * | 1988-08-18 | 1990-02-22 | Green Cross Corp:The | トロンビン乾燥製剤 |
JP2005530714A (ja) * | 2002-03-26 | 2005-10-13 | ソシエテ・ド・コンセイユ・ド・ルシエルシエ・エ・ダアツプリカーション・シヤンテイフイツク・(エス.セー.エール.アー.エス) | 第viii因子を含有する安定な医薬組成物 |
WO2007035455A3 (en) * | 2005-09-16 | 2007-07-26 | Merial Ltd | Stabilizers for freeze-dried vaccines |
JP2007304004A (ja) * | 2006-05-12 | 2007-11-22 | Sekisui Chem Co Ltd | 血液検査用容器 |
US9150637B2 (en) | 2010-11-05 | 2015-10-06 | Baxalta Inc. | Variant of antihemophilic factor VIII having increased specific activity |
CN105879038A (zh) * | 2016-05-27 | 2016-08-24 | 成都蓉生药业有限责任公司 | 一种制备人凝血酶原复合物的干热处理稳定剂及其用途 |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1986007302A1 (en) * | 1985-06-07 | 1986-12-18 | Somar Corporation | Method and device for boring films for film pasting apparatuses |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6089428A (ja) * | 1983-10-19 | 1985-05-20 | Green Cross Corp:The | 血漿蛋白の加熱処理方法 |
JPS6122022A (ja) * | 1983-12-28 | 1986-01-30 | Green Cross Corp:The | 血漿蛋白の加熱処理方法 |
-
1985
- 1985-10-04 JP JP60222453A patent/JPS6281327A/ja active Granted
-
1986
- 1986-10-02 KR KR1019860008265A patent/KR950010321B1/ko not_active Expired - Fee Related
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6089428A (ja) * | 1983-10-19 | 1985-05-20 | Green Cross Corp:The | 血漿蛋白の加熱処理方法 |
JPS6122022A (ja) * | 1983-12-28 | 1986-01-30 | Green Cross Corp:The | 血漿蛋白の加熱処理方法 |
Cited By (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS649937A (en) * | 1987-05-22 | 1989-01-13 | Armour Pharma | Stabilization of biological and pharmacological product of virus and bacteria infected matter in thermal inactivation |
JPH01121224A (ja) * | 1987-11-04 | 1989-05-12 | Green Cross Corp:The | トロンビン含有医薬組成物 |
JPH0253732A (ja) * | 1988-08-18 | 1990-02-22 | Green Cross Corp:The | トロンビン乾燥製剤 |
JP2005530714A (ja) * | 2002-03-26 | 2005-10-13 | ソシエテ・ド・コンセイユ・ド・ルシエルシエ・エ・ダアツプリカーション・シヤンテイフイツク・(エス.セー.エール.アー.エス) | 第viii因子を含有する安定な医薬組成物 |
JP2013147508A (ja) * | 2002-03-26 | 2013-08-01 | Ipsen Pharma Sas | 第viii因子を含有する安定な医薬組成物 |
JP2015143245A (ja) * | 2002-03-26 | 2015-08-06 | イプセン ファルマ ソシエテ パール アクシオン サンプリフィエIpsen Pharma S.A.S. | 第viii因子を含有する安定な医薬組成物 |
WO2007035455A3 (en) * | 2005-09-16 | 2007-07-26 | Merial Ltd | Stabilizers for freeze-dried vaccines |
JP2007304004A (ja) * | 2006-05-12 | 2007-11-22 | Sekisui Chem Co Ltd | 血液検査用容器 |
US9150637B2 (en) | 2010-11-05 | 2015-10-06 | Baxalta Inc. | Variant of antihemophilic factor VIII having increased specific activity |
US10053500B2 (en) | 2010-11-05 | 2018-08-21 | Baxalta Incorporated | Variant of antihemophilic factor VIII having increased specific activity |
CN105879038A (zh) * | 2016-05-27 | 2016-08-24 | 成都蓉生药业有限责任公司 | 一种制备人凝血酶原复合物的干热处理稳定剂及其用途 |
CN105879038B (zh) * | 2016-05-27 | 2020-03-27 | 成都蓉生药业有限责任公司 | 一种制备人凝血酶原复合物的干热处理稳定剂及其用途 |
Also Published As
Publication number | Publication date |
---|---|
KR870003790A (ko) | 1987-05-04 |
KR950010321B1 (ko) | 1995-09-14 |
JPH0376292B2 (enrdf_load_stackoverflow) | 1991-12-05 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US4923815A (en) | Process for heat treating thrombin | |
RU2201252C2 (ru) | Устойчивая, свободная от альбумина лиофилизованная композиция рекомбинантного фактора viii | |
US5130244A (en) | Stable aqueous thrombin solution | |
US4327086A (en) | Process for heat treatment of aqueous solution containing human blood coagulation factor XIII | |
US4424206A (en) | Process for heat treatment of aqueous solution containing cold insoluble globulin to inactivate hepatitis virus | |
JPH0739348B2 (ja) | 血液生産物中の増殖性を有する▲ろ▼過性病原体の不活性化法および血液生産物の製造方法 | |
DK156698B (da) | Fremgangsmaade til pasteurisering af et materiale indeholdende et termisk foelsomt, terapeutisk aktivtprotein valgt blandt alfa-l-antitrypsin, antithrombin-iii, praekallikrein, antihaemofil faktor (faktorviii) og fibronectin | |
CA1237076A (en) | Hepatitis b vaccine | |
EP0278422B1 (en) | y-Globulin injectable solutions | |
JP2012051895A (ja) | ウイルス不活性化熱処理へ供するための血漿タンパク質の寒冷沈降物を安定化する方法 | |
JPH0378373B2 (enrdf_load_stackoverflow) | ||
JPS6281327A (ja) | 人トロンビン製剤の加熱処理方法 | |
JP2605102B2 (ja) | ウイルスおよびバクテリア汚染物の熱的不活性化中の生物学的および製薬的生成物の安定化 | |
JPH0366292B2 (enrdf_load_stackoverflow) | ||
JPS6054287B2 (ja) | 血漿蛋白の加熱処理方法 | |
US5116950A (en) | Process for heat treating fibrinogen | |
JPS6122022A (ja) | 血漿蛋白の加熱処理方法 | |
JPS6289628A (ja) | 人フイブリノゲン製剤の加熱処理法 | |
JPS62289523A (ja) | 静脈投与用免疫グロブリンの加熱処理方法 | |
JP2717638B2 (ja) | 人血液凝固第ix因子含有製剤 | |
JPS6140392B2 (enrdf_load_stackoverflow) | ||
JP4146525B2 (ja) | アンチトロンビン−iiiの精製法 | |
JPH0278633A (ja) | ウイルス不活化方法 | |
JP4105249B2 (ja) | α2プラスミンインヒビターの製造方法 | |
JPH0296536A (ja) | プラスミノゲン乾燥製剤 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
LAPS | Cancellation because of no payment of annual fees |