JPS6281327A - 人トロンビン製剤の加熱処理方法 - Google Patents

人トロンビン製剤の加熱処理方法

Info

Publication number
JPS6281327A
JPS6281327A JP60222453A JP22245385A JPS6281327A JP S6281327 A JPS6281327 A JP S6281327A JP 60222453 A JP60222453 A JP 60222453A JP 22245385 A JP22245385 A JP 22245385A JP S6281327 A JPS6281327 A JP S6281327A
Authority
JP
Japan
Prior art keywords
thrombin
heat treatment
stabilizer
heating
virus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP60222453A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0376292B2 (enrdf_load_stackoverflow
Inventor
Hideo Nishimaki
西槇 秀雄
Matsuhisa Kameyama
松寿 亀山
Hideyuki Ishikawa
英之 石川
Hironobu Watanabe
渡辺 博信
Yoshiro Iga
伊賀 善郎
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Tanabe Pharma Corp
GC Biopharma Corp
Original Assignee
Green Cross Corp Japan
Green Cross Corp Korea
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Green Cross Corp Japan, Green Cross Corp Korea filed Critical Green Cross Corp Japan
Priority to JP60222453A priority Critical patent/JPS6281327A/ja
Priority to KR1019860008265A priority patent/KR950010321B1/ko
Publication of JPS6281327A publication Critical patent/JPS6281327A/ja
Publication of JPH0376292B2 publication Critical patent/JPH0376292B2/ja
Granted legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
JP60222453A 1985-10-04 1985-10-04 人トロンビン製剤の加熱処理方法 Granted JPS6281327A (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP60222453A JPS6281327A (ja) 1985-10-04 1985-10-04 人トロンビン製剤の加熱処理方法
KR1019860008265A KR950010321B1 (ko) 1985-10-04 1986-10-02 인간 트롬빈 제제의 가열처리방법

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP60222453A JPS6281327A (ja) 1985-10-04 1985-10-04 人トロンビン製剤の加熱処理方法

Publications (2)

Publication Number Publication Date
JPS6281327A true JPS6281327A (ja) 1987-04-14
JPH0376292B2 JPH0376292B2 (enrdf_load_stackoverflow) 1991-12-05

Family

ID=16782647

Family Applications (1)

Application Number Title Priority Date Filing Date
JP60222453A Granted JPS6281327A (ja) 1985-10-04 1985-10-04 人トロンビン製剤の加熱処理方法

Country Status (2)

Country Link
JP (1) JPS6281327A (enrdf_load_stackoverflow)
KR (1) KR950010321B1 (enrdf_load_stackoverflow)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS649937A (en) * 1987-05-22 1989-01-13 Armour Pharma Stabilization of biological and pharmacological product of virus and bacteria infected matter in thermal inactivation
JPH01121224A (ja) * 1987-11-04 1989-05-12 Green Cross Corp:The トロンビン含有医薬組成物
JPH0253732A (ja) * 1988-08-18 1990-02-22 Green Cross Corp:The トロンビン乾燥製剤
JP2005530714A (ja) * 2002-03-26 2005-10-13 ソシエテ・ド・コンセイユ・ド・ルシエルシエ・エ・ダアツプリカーション・シヤンテイフイツク・(エス.セー.エール.アー.エス) 第viii因子を含有する安定な医薬組成物
WO2007035455A3 (en) * 2005-09-16 2007-07-26 Merial Ltd Stabilizers for freeze-dried vaccines
JP2007304004A (ja) * 2006-05-12 2007-11-22 Sekisui Chem Co Ltd 血液検査用容器
US9150637B2 (en) 2010-11-05 2015-10-06 Baxalta Inc. Variant of antihemophilic factor VIII having increased specific activity
CN105879038A (zh) * 2016-05-27 2016-08-24 成都蓉生药业有限责任公司 一种制备人凝血酶原复合物的干热处理稳定剂及其用途

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986007302A1 (en) * 1985-06-07 1986-12-18 Somar Corporation Method and device for boring films for film pasting apparatuses

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6089428A (ja) * 1983-10-19 1985-05-20 Green Cross Corp:The 血漿蛋白の加熱処理方法
JPS6122022A (ja) * 1983-12-28 1986-01-30 Green Cross Corp:The 血漿蛋白の加熱処理方法

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6089428A (ja) * 1983-10-19 1985-05-20 Green Cross Corp:The 血漿蛋白の加熱処理方法
JPS6122022A (ja) * 1983-12-28 1986-01-30 Green Cross Corp:The 血漿蛋白の加熱処理方法

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS649937A (en) * 1987-05-22 1989-01-13 Armour Pharma Stabilization of biological and pharmacological product of virus and bacteria infected matter in thermal inactivation
JPH01121224A (ja) * 1987-11-04 1989-05-12 Green Cross Corp:The トロンビン含有医薬組成物
JPH0253732A (ja) * 1988-08-18 1990-02-22 Green Cross Corp:The トロンビン乾燥製剤
JP2005530714A (ja) * 2002-03-26 2005-10-13 ソシエテ・ド・コンセイユ・ド・ルシエルシエ・エ・ダアツプリカーション・シヤンテイフイツク・(エス.セー.エール.アー.エス) 第viii因子を含有する安定な医薬組成物
JP2013147508A (ja) * 2002-03-26 2013-08-01 Ipsen Pharma Sas 第viii因子を含有する安定な医薬組成物
JP2015143245A (ja) * 2002-03-26 2015-08-06 イプセン ファルマ ソシエテ パール アクシオン サンプリフィエIpsen Pharma S.A.S. 第viii因子を含有する安定な医薬組成物
WO2007035455A3 (en) * 2005-09-16 2007-07-26 Merial Ltd Stabilizers for freeze-dried vaccines
JP2007304004A (ja) * 2006-05-12 2007-11-22 Sekisui Chem Co Ltd 血液検査用容器
US9150637B2 (en) 2010-11-05 2015-10-06 Baxalta Inc. Variant of antihemophilic factor VIII having increased specific activity
US10053500B2 (en) 2010-11-05 2018-08-21 Baxalta Incorporated Variant of antihemophilic factor VIII having increased specific activity
CN105879038A (zh) * 2016-05-27 2016-08-24 成都蓉生药业有限责任公司 一种制备人凝血酶原复合物的干热处理稳定剂及其用途
CN105879038B (zh) * 2016-05-27 2020-03-27 成都蓉生药业有限责任公司 一种制备人凝血酶原复合物的干热处理稳定剂及其用途

Also Published As

Publication number Publication date
KR870003790A (ko) 1987-05-04
KR950010321B1 (ko) 1995-09-14
JPH0376292B2 (enrdf_load_stackoverflow) 1991-12-05

Similar Documents

Publication Publication Date Title
US4923815A (en) Process for heat treating thrombin
RU2201252C2 (ru) Устойчивая, свободная от альбумина лиофилизованная композиция рекомбинантного фактора viii
US5130244A (en) Stable aqueous thrombin solution
US4327086A (en) Process for heat treatment of aqueous solution containing human blood coagulation factor XIII
US4424206A (en) Process for heat treatment of aqueous solution containing cold insoluble globulin to inactivate hepatitis virus
JPH0739348B2 (ja) 血液生産物中の増殖性を有する▲ろ▼過性病原体の不活性化法および血液生産物の製造方法
DK156698B (da) Fremgangsmaade til pasteurisering af et materiale indeholdende et termisk foelsomt, terapeutisk aktivtprotein valgt blandt alfa-l-antitrypsin, antithrombin-iii, praekallikrein, antihaemofil faktor (faktorviii) og fibronectin
CA1237076A (en) Hepatitis b vaccine
EP0278422B1 (en) y-Globulin injectable solutions
JP2012051895A (ja) ウイルス不活性化熱処理へ供するための血漿タンパク質の寒冷沈降物を安定化する方法
JPH0378373B2 (enrdf_load_stackoverflow)
JPS6281327A (ja) 人トロンビン製剤の加熱処理方法
JP2605102B2 (ja) ウイルスおよびバクテリア汚染物の熱的不活性化中の生物学的および製薬的生成物の安定化
JPH0366292B2 (enrdf_load_stackoverflow)
JPS6054287B2 (ja) 血漿蛋白の加熱処理方法
US5116950A (en) Process for heat treating fibrinogen
JPS6122022A (ja) 血漿蛋白の加熱処理方法
JPS6289628A (ja) 人フイブリノゲン製剤の加熱処理法
JPS62289523A (ja) 静脈投与用免疫グロブリンの加熱処理方法
JP2717638B2 (ja) 人血液凝固第ix因子含有製剤
JPS6140392B2 (enrdf_load_stackoverflow)
JP4146525B2 (ja) アンチトロンビン−iiiの精製法
JPH0278633A (ja) ウイルス不活化方法
JP4105249B2 (ja) α2プラスミンインヒビターの製造方法
JPH0296536A (ja) プラスミノゲン乾燥製剤

Legal Events

Date Code Title Description
LAPS Cancellation because of no payment of annual fees