JPS627169B2 - - Google Patents
Info
- Publication number
- JPS627169B2 JPS627169B2 JP52156546A JP15654677A JPS627169B2 JP S627169 B2 JPS627169 B2 JP S627169B2 JP 52156546 A JP52156546 A JP 52156546A JP 15654677 A JP15654677 A JP 15654677A JP S627169 B2 JPS627169 B2 JP S627169B2
- Authority
- JP
- Japan
- Prior art keywords
- activated carbon
- spherical
- constipation
- charcoal
- day
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 79
- 230000000694 effects Effects 0.000 claims description 22
- 206010010774 Constipation Diseases 0.000 claims description 20
- 239000011148 porous material Substances 0.000 claims description 8
- 239000000729 antidote Substances 0.000 claims description 3
- 239000003610 charcoal Substances 0.000 description 11
- 239000000126 substance Substances 0.000 description 8
- 238000000034 method Methods 0.000 description 7
- 239000000523 sample Substances 0.000 description 7
- 238000001784 detoxification Methods 0.000 description 5
- UFWIBTONFRDIAS-UHFFFAOYSA-N Naphthalene Chemical compound C1=CC=CC2=CC=CC=C21 UFWIBTONFRDIAS-UHFFFAOYSA-N 0.000 description 4
- 230000013872 defecation Effects 0.000 description 4
- 210000002249 digestive system Anatomy 0.000 description 4
- 229940079593 drug Drugs 0.000 description 4
- 239000003814 drug Substances 0.000 description 4
- 235000012054 meals Nutrition 0.000 description 4
- 239000002245 particle Substances 0.000 description 4
- 239000002994 raw material Substances 0.000 description 4
- 238000001179 sorption measurement Methods 0.000 description 4
- 208000024891 symptom Diseases 0.000 description 4
- 238000012360 testing method Methods 0.000 description 4
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
- 206010000496 acne Diseases 0.000 description 3
- 230000037396 body weight Effects 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 230000000968 intestinal effect Effects 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 230000036407 pain Effects 0.000 description 3
- 239000012798 spherical particle Substances 0.000 description 3
- 206010012735 Diarrhoea Diseases 0.000 description 2
- SIKJAQJRHWYJAI-UHFFFAOYSA-N Indole Chemical compound C1=CC=C2NC=CC2=C1 SIKJAQJRHWYJAI-UHFFFAOYSA-N 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
- 241000699670 Mus sp. Species 0.000 description 2
- 230000002159 abnormal effect Effects 0.000 description 2
- 230000005856 abnormality Effects 0.000 description 2
- 230000004913 activation Effects 0.000 description 2
- 231100000215 acute (single dose) toxicity testing Toxicity 0.000 description 2
- 238000011047 acute toxicity test Methods 0.000 description 2
- 239000007864 aqueous solution Substances 0.000 description 2
- 230000000052 comparative effect Effects 0.000 description 2
- 238000007796 conventional method Methods 0.000 description 2
- 230000003247 decreasing effect Effects 0.000 description 2
- 230000001747 exhibiting effect Effects 0.000 description 2
- 210000000936 intestine Anatomy 0.000 description 2
- JCQLYHFGKNRPGE-FCVZTGTOSA-N lactulose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 JCQLYHFGKNRPGE-FCVZTGTOSA-N 0.000 description 2
- 229960000511 lactulose Drugs 0.000 description 2
- PFCRQPBOOFTZGQ-UHFFFAOYSA-N lactulose keto form Natural products OCC(=O)C(O)C(C(O)CO)OC1OC(CO)C(O)C(O)C1O PFCRQPBOOFTZGQ-UHFFFAOYSA-N 0.000 description 2
- LQNUZADURLCDLV-UHFFFAOYSA-N nitrobenzene Chemical compound [O-][N+](=O)C1=CC=CC=C1 LQNUZADURLCDLV-UHFFFAOYSA-N 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- 210000002784 stomach Anatomy 0.000 description 2
- 238000012546 transfer Methods 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- QHGUCRYDKWKLMG-QMMMGPOBSA-N (R)-octopamine Chemical compound NC[C@H](O)C1=CC=C(O)C=C1 QHGUCRYDKWKLMG-QMMMGPOBSA-N 0.000 description 1
- 206010002091 Anaesthesia Diseases 0.000 description 1
- 241000193738 Bacillus anthracis Species 0.000 description 1
- 208000035143 Bacterial infection Diseases 0.000 description 1
- 206010008631 Cholera Diseases 0.000 description 1
- 235000013162 Cocos nucifera Nutrition 0.000 description 1
- 244000060011 Cocos nucifera Species 0.000 description 1
- 206010010071 Coma Diseases 0.000 description 1
- 208000022540 Consciousness disease Diseases 0.000 description 1
- IMROMDMJAWUWLK-UHFFFAOYSA-N Ethenol Chemical compound OC=C IMROMDMJAWUWLK-UHFFFAOYSA-N 0.000 description 1
- 206010016952 Food poisoning Diseases 0.000 description 1
- 208000019331 Foodborne disease Diseases 0.000 description 1
- 208000007882 Gastritis Diseases 0.000 description 1
- QHGUCRYDKWKLMG-MRVPVSSYSA-N Octopamine Natural products NC[C@@H](O)C1=CC=C(O)C=C1 QHGUCRYDKWKLMG-MRVPVSSYSA-N 0.000 description 1
- 239000004372 Polyvinyl alcohol Substances 0.000 description 1
- 241000700157 Rattus norvegicus Species 0.000 description 1
- 206010070863 Toxicity to various agents Diseases 0.000 description 1
- 208000037386 Typhoid Diseases 0.000 description 1
- 229940082079 activated charcoal / magnesium hydroxide Drugs 0.000 description 1
- 231100000354 acute hepatitis Toxicity 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 230000037005 anaesthesia Effects 0.000 description 1
- 238000010171 animal model Methods 0.000 description 1
- 239000007900 aqueous suspension Substances 0.000 description 1
- 208000022362 bacterial infectious disease Diseases 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 238000007664 blowing Methods 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 239000005539 carbonized material Substances 0.000 description 1
- 210000002318 cardia Anatomy 0.000 description 1
- 208000023652 chronic gastritis Diseases 0.000 description 1
- 239000003245 coal Substances 0.000 description 1
- 230000002301 combined effect Effects 0.000 description 1
- 239000010779 crude oil Substances 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000006866 deterioration Effects 0.000 description 1
- 208000002173 dizziness Diseases 0.000 description 1
- 239000003651 drinking water Substances 0.000 description 1
- 235000020188 drinking water Nutrition 0.000 description 1
- 239000003937 drug carrier Substances 0.000 description 1
- 208000001848 dysentery Diseases 0.000 description 1
- 201000006549 dyspepsia Diseases 0.000 description 1
- 206010015037 epilepsy Diseases 0.000 description 1
- -1 etc. Substances 0.000 description 1
- 238000002146 exchange transfusion Methods 0.000 description 1
- 230000029142 excretion Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 230000001815 facial effect Effects 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 238000000227 grinding Methods 0.000 description 1
- 230000002650 habitual effect Effects 0.000 description 1
- 208000006454 hepatitis Diseases 0.000 description 1
- PZOUSPYUWWUPPK-UHFFFAOYSA-N indole Natural products CC1=CC=CC2=C1C=CN2 PZOUSPYUWWUPPK-UHFFFAOYSA-N 0.000 description 1
- RKJUIXBNRJVNHR-UHFFFAOYSA-N indolenine Natural products C1=CC=C2CC=NC2=C1 RKJUIXBNRJVNHR-UHFFFAOYSA-N 0.000 description 1
- 208000028774 intestinal disease Diseases 0.000 description 1
- 239000002085 irritant Substances 0.000 description 1
- 231100000021 irritant Toxicity 0.000 description 1
- 208000019423 liver disease Diseases 0.000 description 1
- VTHJTEIRLNZDEV-UHFFFAOYSA-L magnesium dihydroxide Chemical compound [OH-].[OH-].[Mg+2] VTHJTEIRLNZDEV-UHFFFAOYSA-L 0.000 description 1
- 229910001862 magnesium hydroxide Inorganic materials 0.000 description 1
- 239000000347 magnesium hydroxide Substances 0.000 description 1
- 229940105082 medicinal charcoal Drugs 0.000 description 1
- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 description 1
- 229910052753 mercury Inorganic materials 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 229960001576 octopamine Drugs 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 230000007096 poisonous effect Effects 0.000 description 1
- 229920002451 polyvinyl alcohol Polymers 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000013094 purity test Methods 0.000 description 1
- 210000000664 rectum Anatomy 0.000 description 1
- 238000007873 sieving Methods 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 239000000375 suspending agent Substances 0.000 description 1
- 229920001059 synthetic polymer Polymers 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 108700012359 toxins Proteins 0.000 description 1
- 201000008297 typhoid fever Diseases 0.000 description 1
- 238000009423 ventilation Methods 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
- 238000004383 yellowing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/44—Elemental carbon, e.g. charcoal, carbon black
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Inorganic Chemistry (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Carbon And Carbon Compounds (AREA)
- External Artificial Organs (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Medicinal Preparation (AREA)
Priority Applications (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP15654677A JPS5489010A (en) | 1977-12-27 | 1977-12-27 | Spherical activated charcoal antidote |
| CA318,549A CA1112172A (en) | 1977-12-27 | 1978-12-22 | Antidote consisting of particles of activated carbon |
| GB7849806A GB2012257B (en) | 1977-12-27 | 1978-12-22 | Particles of activated carbon and their use in combatting gastrointrstinal illnesses |
| DE2855825A DE2855825C2 (de) | 1977-12-27 | 1978-12-22 | Verwendung von Aktivkohleteilchen als Antidot |
| ES476321A ES476321A1 (es) | 1977-12-27 | 1978-12-26 | Mejoras en la preparacion de antidotos cosistentes en parti-culas de carbono activado. |
| FR7836293A FR2413092A1 (fr) | 1977-12-27 | 1978-12-26 | Produit a base de particules de charbon actif et son application en tant qu'antidote |
| NL7812550A NL7812550A (nl) | 1977-12-27 | 1978-12-27 | Actieve kool als tegengif. |
| US06/759,933 US4761284A (en) | 1977-12-27 | 1985-07-29 | Antidote including activated carbon particles |
| US07/047,291 US4822765A (en) | 1977-12-27 | 1987-05-08 | Process for treating activated carbon with aqueous ammonia |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP15654677A JPS5489010A (en) | 1977-12-27 | 1977-12-27 | Spherical activated charcoal antidote |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5489010A JPS5489010A (en) | 1979-07-14 |
| JPS627169B2 true JPS627169B2 (es) | 1987-02-16 |
Family
ID=15630152
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP15654677A Granted JPS5489010A (en) | 1977-12-27 | 1977-12-27 | Spherical activated charcoal antidote |
Country Status (7)
| Country | Link |
|---|---|
| JP (1) | JPS5489010A (es) |
| CA (1) | CA1112172A (es) |
| DE (1) | DE2855825C2 (es) |
| ES (1) | ES476321A1 (es) |
| FR (1) | FR2413092A1 (es) |
| GB (1) | GB2012257B (es) |
| NL (1) | NL7812550A (es) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS565313A (en) * | 1979-06-26 | 1981-01-20 | Kureha Chem Ind Co Ltd | Detoxificating spherical active carbon and preparing the same |
| US4761284A (en) * | 1977-12-27 | 1988-08-02 | Kureha Kagaku Kogy Kabushiki Kaisha | Antidote including activated carbon particles |
| JPS5673542A (en) * | 1979-11-22 | 1981-06-18 | Kureha Chem Ind Co Ltd | Adsorbent |
| JPS5731864A (en) * | 1980-08-04 | 1982-02-20 | Teijin Ltd | Oral activated carbon microcapsule |
| DE3819000A1 (de) * | 1988-06-03 | 1989-12-14 | Hasso Von Bluecher | Beutel in der art eines teebeutels zur beseitigung von schadstoffen |
| IT1273678B (it) * | 1993-08-12 | 1997-07-09 | Bluecher Hasso Von | Processo per la produzione di carbone attivo |
| NL1000078C2 (nl) * | 1994-04-19 | 1996-04-22 | Bluecher Hasso Von | Geurfilter voor stofzuigers. |
| SE515506C2 (sv) * | 1994-06-17 | 2001-08-20 | Mhb Filtration Gmbh & Co Kg | Luktfilter för ventilationsutloppshuvar |
| SE509743C2 (sv) * | 1994-06-17 | 1999-03-01 | Bluecher Hasso Von | Adsorptionsfilterskikt |
| FR2745981B1 (fr) * | 1996-03-15 | 1998-06-05 | Agent adsorbant diminuant ou eliminant les effets secondaires lies a l'absorption d'agents edulcorants | |
| JPH1129485A (ja) * | 1997-07-10 | 1999-02-02 | Kureha Chem Ind Co Ltd | 抗肥満剤 |
| JP3522708B2 (ja) * | 2001-04-11 | 2004-04-26 | 呉羽化学工業株式会社 | 経口投与用吸着剤 |
| CA2504514C (en) * | 2002-11-01 | 2008-08-12 | Kureha Chemical Industry Co., Ltd. | Adsorbent for oral administration |
| US7651974B2 (en) | 2002-11-01 | 2010-01-26 | Kureha Chemical Industry Co., Ltd. | Adsorbent for oral administration |
| KR101135260B1 (ko) | 2003-10-22 | 2012-04-12 | 가부시키가이샤 쿠레하 | 경구투여용 흡착제, 신질환 치료 또는 예방제 및 간질환치료 또는 예방제 |
| US20070231394A1 (en) * | 2004-02-06 | 2007-10-04 | Sumie Goto | Agent for Removing Circulatory Dysfunction Factor |
| TWI370012B (en) | 2004-04-02 | 2012-08-11 | Kureha Corp | Adsorbent for oral administration, and agent for treating or preventing renal or liver disease |
| TWI370013B (en) | 2004-04-02 | 2012-08-11 | Kureha Corp | Adsorbent for oral administration, and agent for treating or preventing renal or liver disease |
| WO2005115611A1 (ja) * | 2004-05-31 | 2005-12-08 | Teikoku Medix Co., Ltd. | 吸着剤およびその製造法 |
| US8247072B2 (en) | 2006-02-14 | 2012-08-21 | Eastman Chemical Company | Resol beads, methods of making them and methods of using them |
| CA2670683A1 (en) * | 2006-11-27 | 2008-06-05 | Denovo, Inc. | Decontaminant edible product, methods of production and uses thereof |
| JP5984352B2 (ja) * | 2010-10-12 | 2016-09-06 | フタムラ化学株式会社 | 経口投与用医薬用吸着剤の製造方法 |
| JP5985027B2 (ja) * | 2010-10-12 | 2016-09-06 | フタムラ化学株式会社 | 経口投与用医薬用吸着剤の製造方法 |
| WO2014044794A2 (en) | 2012-09-21 | 2014-03-27 | Ferring Bv | Pharmaceutical composition |
| US9682101B2 (en) | 2013-03-25 | 2017-06-20 | Ferring B.V. | Composition for the treatment of disease |
| KR101924201B1 (ko) * | 2014-02-07 | 2018-12-03 | 대원제약주식회사 | 강도가 증가된 경구 투여형 의약용 흡착제 |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4983690A (es) * | 1972-12-20 | 1974-08-12 | ||
| JPS49126591A (es) * | 1973-04-10 | 1974-12-04 | ||
| JPS5018879A (es) * | 1973-06-20 | 1975-02-27 | ||
| JPS5051996A (es) * | 1973-09-11 | 1975-05-09 | ||
| JPS51148291A (en) * | 1975-06-13 | 1976-12-20 | Teijin Ltd | Artificial organ |
| JPS51151693A (en) * | 1975-06-23 | 1976-12-27 | Eisai Co Ltd | Coated bead-like activated carbon for blood purification |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5018879B2 (es) * | 1971-08-27 | 1975-07-02 | ||
| DE2410372C2 (de) * | 1974-03-05 | 1982-03-04 | Kureha Kagaku Kogyo K.K., Tokyo | Verfahren zum Reaktivieren von verbrauchter praktisch kugelförmiger Aktivkohle kleiner Größe |
-
1977
- 1977-12-27 JP JP15654677A patent/JPS5489010A/ja active Granted
-
1978
- 1978-12-22 GB GB7849806A patent/GB2012257B/en not_active Expired
- 1978-12-22 CA CA318,549A patent/CA1112172A/en not_active Expired
- 1978-12-22 DE DE2855825A patent/DE2855825C2/de not_active Expired
- 1978-12-26 ES ES476321A patent/ES476321A1/es not_active Expired
- 1978-12-26 FR FR7836293A patent/FR2413092A1/fr active Granted
- 1978-12-27 NL NL7812550A patent/NL7812550A/xx active Search and Examination
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4983690A (es) * | 1972-12-20 | 1974-08-12 | ||
| JPS49126591A (es) * | 1973-04-10 | 1974-12-04 | ||
| JPS5018879A (es) * | 1973-06-20 | 1975-02-27 | ||
| JPS5051996A (es) * | 1973-09-11 | 1975-05-09 | ||
| JPS51148291A (en) * | 1975-06-13 | 1976-12-20 | Teijin Ltd | Artificial organ |
| JPS51151693A (en) * | 1975-06-23 | 1976-12-27 | Eisai Co Ltd | Coated bead-like activated carbon for blood purification |
Also Published As
| Publication number | Publication date |
|---|---|
| GB2012257A (en) | 1979-07-25 |
| ES476321A1 (es) | 1979-06-16 |
| DE2855825A1 (de) | 1979-06-28 |
| FR2413092B1 (es) | 1982-11-19 |
| FR2413092A1 (fr) | 1979-07-27 |
| NL7812550A (nl) | 1979-06-29 |
| GB2012257B (en) | 1983-03-30 |
| CA1112172A (en) | 1981-11-10 |
| JPS5489010A (en) | 1979-07-14 |
| DE2855825C2 (de) | 1984-03-01 |
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